A marina with numerous boats docked, a lighthouse, and a sunset in the background.

Search Business Hotels in Mexico and Central America

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Mexico and Central America Accommodation: Most Popular Cities to Stay

A bustling street with historic buildings, flags, and pedestrians.
HotelsHotels

Mexico City

Mexico City

Check availability on Mexico and Central America Business Hotels

Our top choices for Mexico and Central America business-friendly hotels

A rooftop pool with sun loungers and umbrellas, surrounded by palm trees and modern buildings.

1. Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (6,102 reviews)
"Pleasant staff throughout, definitely will stay there next time in Panama."
United States
Damien
The price is ₹11,359
₹12,495 total
includes taxes & fees
26 Oct - 27 Oct
Hotel Riu Plaza Panama
A rooftop pool area with lounge chairs and a yoga studio.

2. Galeria Plaza Reforma

Galeria Plaza Reforma
4.0 star property
Reforma
9.4 out of 10, Exceptional, (3,677 reviews)
"Great location, clean rooms and friendly staff"
Australia
Abhishek
The price is ₹12,688
₹15,162 total
includes taxes & fees
8 Nov - 9 Nov
Galeria Plaza Reforma
A restaurant with wooden flooring, round tables, and leather booths.

3. InterContinental Presidente Mexico City by IHG

InterContinental Presidente Mexico City by IHG
4.0 star property
Polanco
9.4 out of 10, Exceptional, (2,480 reviews)
"GREAT LOCATION"
United States
Alfonso
The price is ₹41,673
₹49,799 total
includes taxes & fees
25 Oct - 26 Oct
InterContinental Presidente Mexico City by IHG
A spacious living room with a large window offering a city view, a dining area with a table and chairs, and a comfortable seating arrangement.

4. Sheraton Maria Isabel Mexico City Reforma

Sheraton Maria Isabel Mexico City Reforma
4.0 star property
Reforma
9.2 out of 10, Wonderful, (2,372 reviews)
"Excelente hotel"
Mexico
Julian
The price is ₹17,163
₹20,509 total
includes taxes & fees
15 Nov - 16 Nov
Sheraton Maria Isabel Mexico City Reforma
A spacious lobby with a modern staircase, two armchairs, and a large abstract wall structure.

5. Hyatt Regency Mexico City

Hyatt Regency Mexico City
5.0 star property
Polanco
9.4 out of 10, Exceptional, (1,508 reviews)
"Amazing location, Amazing Staff and Great rooms !"
United States
Angel
The price is ₹36,654
₹43,801 total
includes taxes & fees
13 Nov - 14 Nov
Hyatt Regency Mexico City
An indoor venue with tables and chairs arranged for dining, surrounded by draped fabric and string lights.

6. Barceló Guatemala City

Barceló Guatemala City
4.5 star property
Zona 9
9.2 out of 10, Wonderful, (3,315 reviews)
"Nice place"
United States
Maritza
The price is ₹9,384
₹11,448 total
includes taxes & fees
25 Oct - 26 Oct
Barceló Guatemala City
Front of property

7. Camino Real Aeropuerto Mexico

Camino Real Aeropuerto Mexico
4.0 star property
Venustiano Carranza
8.8 out of 10, Excellent, (14,280 reviews)
"Great and convenient property with very nice and attentive staff."
United States
Catalina
The price is ₹12,990
₹15,523 total
includes taxes & fees
7 Nov - 8 Nov
Camino Real Aeropuerto Mexico
A swimming pool with two smaller pools and a glass ceiling structure.

8. Barceló México Reforma

Barceló México Reforma
4.5 star property
Reforma
9.4 out of 10, Exceptional, (5,535 reviews)
"Great location and delicious breakfast."
United States
GABRIELA
The price is ₹17,134
₹20,475 total
includes taxes & fees
15 Nov - 16 Nov
Barceló México Reforma
A modern hotel entrance with a prominent 'NOVOTEL' sign, large glass windows, and geometric light patterns on the facade.

9. Novotel Panama City

Novotel Panama City
4.0 star property
Bella Vista
9.2 out of 10, Wonderful, (1,296 reviews)
"Nice place to stay."
United States
CARLOS
The price is ₹10,423
₹11,465 total
includes taxes & fees
8 Nov - 9 Nov
Novotel Panama City
An outdoor seating area with wicker chairs and tables, overlooking a cityscape.

10. Hotel Riu Plaza Guadalajara

Hotel Riu Plaza Guadalajara
5.0 star property
Zona Expo
9.2 out of 10, Wonderful, (4,561 reviews)
"Excelente hotel"
United States
Armando
The price is ₹11,471
₹13,880 total
includes taxes & fees
3 Nov - 4 Nov
Hotel Riu Plaza Guadalajara
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Mexico and Central America Hotel Reviews

Live Aqua Cancun - Adults Only - All-Inclusive

Live Aqua Cancun - Adults Only - All-Inclusive

10/10 Excellent
"This was me and my husband’s first time in Cancun and it could not have been better! We stayed in the oceanfront aqua club and it was absolutely perfect. The room was extremely clean, the view was breathtaking. The food at this resort was very very good for a resort. You are only a few mins uber ride from the restaurants on the strip if you want to leave but you don’t really need to with all the restaurants on the property. This is NOT a party resort so if you are looking for that, you will not find that here. But if you are looking for a relaxing vacation where you don’t need to leave the property, this is it! We will be coming back every year."
Elijah 3-night trip
Posted 5 hours ago
Live Aqua Cancun - Adults Only - All-Inclusive

Explore a world of travel with Expedia