Medical Center District Travel Guide

San Antonio

River walk in San Antonio
Riverboat on the San Antonio River Walk, San Antonio, Texas, United States of America.
River walk in San Antonio
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Popular places to visit


Top hotels in Medical Center District

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3 out of 5
4431 Horizon Hill Blvd San Antonio TX
The price is ₹7,559 per night from 28 May to 29 May
₹7,559
₹8,935 total
28 May - 29 May
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (3,340 reviews)
Awesome staff as always great breakfast as always

Reviewed on 8 May 2026

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

3.5 out of 5
3233 NW Loop 410 San Antonio TX
The price is ₹9,557 per night from 15 May to 16 May
₹9,557
₹11,357 total
15 May - 16 May
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy a free local area shuttle, room service and a 24-hour fitness centre. Our guests praise the helpful ...
8.6/10 Excellent! (1,055 reviews)
Love this place. Nice and clean rooms.

Reviewed on 5 May 2026

San Antonio Marriott Northwest Medical Center
Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio

3 out of 5
8585 Marriott Dr San Antonio TX
The price is ₹9,236 per night from 24 May to 25 May
₹9,236
₹10,918 total
24 May - 25 May
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,009 reviews)
When I checked for a week and payed CASH IN TOWN FOR A MILITARY EVENT AT LACKLAND AFB DRIVE 25 hours, NO ONE INFORMED ME IF I HAD TO LEAVE EARLY I NEED TO GIVE A NOTICE OR THE HOTEL WOULD RETAIN A FEE OF 129.00. It just not a way to handle playing customers of over 25 years!

Reviewed on 8 May 2026

Courtyard by Marriott Medical Center San Antonio
Drury Plaza Hotel San Antonio Riverwalk

Drury Plaza Hotel San Antonio Riverwalk

4 out of 5
105 S Saint Marys Street San Antonio TX
The price is ₹14,172 per night from 7 Jun to 8 Jun
₹14,172
₹16,752 total
7 Jun - 8 Jun
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and 2 hot tubs. Our guests praise the breakfast and the pool in their reviews. ...
9.4/10 Exceptional! (4,605 reviews)
Staff is very accommodating and pleasant. From the front desk, dining and housekeeping staff. Each and Everyone working there that me and my husband have encountered or interacted with is just giving is the impression that they are just happy to be working there.

Reviewed on 9 May 2026

Drury Plaza Hotel San Antonio Riverwalk
Riverwalk Plaza

Riverwalk Plaza

4 out of 5
100 Villita Street San Antonio TX
Fully refundableReserve now, pay when you stay
The price is ₹8,398 per night from 11 May to 12 May
₹8,398
₹9,927 total
11 May - 12 May
includes taxes & fees
Stay at this family-friendly hotel in San Antonio. Enjoy free Wi-Fi, room service and a 24-hour fitness centre. Our guests praise the restaurant and the helpful ...
8/10 Very Good! (6,461 reviews)
There was a lot humidity in my room.. But other than that it was a good stay.

Reviewed on 8 May 2026

Riverwalk Plaza
Hyatt Regency Hill Country Resort and Villas

Hyatt Regency Hill Country Resort and Villas

4 out of 5
9800 Hyatt Resort Dr San Antonio TX
The price is ₹32,044 per night from 17 May to 18 May
₹32,044
₹45,279 total
17 May - 18 May
includes taxes & fees
Stay at this golf hotel in San Antonio. Enjoy free Wi-Fi, 3 outdoor pools and 5 restaurants. Our guests praise the helpful staff and the clean rooms in their ...
8.8/10 Excellent! (1,004 reviews)
Gorgeous place and jacob at the desk sang happy birthday to my wife upon check in! Beautiful stay!

Reviewed on 28 Apr 2026

Hyatt Regency Hill Country Resort and Villas
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Medical Center District

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Northwest Side

If you're spending some time in Northwest Side, Huebner Oaks and Convocation Center are top sights worth seeing.

Northwest Side
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Shearer Hills - Ridgeview

While visiting Shearer Hills - Ridgeview, you might make a stop by sights like North Star Mall and San Pedro Driving Range & Par 3 Course.

Shearer Hills - Ridgeview
River Walk in San Antonio, Texas

Midtown

Unique features of Midtown include the river views and bars. Make a stop by San Antonio Zoo and Aquarium or San Antonio River while you're exploring the area.

Midtown
Historic architecture Spanish San Antonio Texas Mission San Jose on a cloudy day

La Cantera District

If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

La Cantera District
Tobin Hill

Tobin Hill

Tobin Hill might not have many top sights, but San Antonio Zoo and Aquarium and San Antonio Museum of Art are two attractions nearby that you can check out.

Tobin Hill
Dallas Skyline Reflection on Trinity River During Sunset, Dallas, Texas.

Uptown

If you're spending some time in Uptown, San Antonio Zoo and Aquarium and Marion Koogler McNay Art Museum are top sights worth seeing.

Uptown


Medical Center District Travel Guide

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