Medical Center District Travel Guide
San Antonio
Visit Medical Center District
Popular places to visit
River Walk
River Walk is just one of the places to see in San Antonio, so why not enjoy the other things to explore during your travels? Discover the lively festivals and shops in this walkable area.
Six Flags Fiesta Texas
Enjoy the excitement at Six Flags Fiesta Texas and see why people love this theme park in San Antonio. Experience the acclaimed theatre scene and entertainment choices in this family-friendly area.
Lackland Air Force Base
Lackland Air Force Base is just one of the places to see in San Antonio, so why not enjoy the other things to explore during your travels? Discover the entertainment venues and shops in this family-friendly area.
San Antonio SeaWorld
Make time to visit the sea life at San Antonio SeaWorld, and find out why this is a popular attraction in San Antonio. Amble around this family-friendly area's seaside or experience its lively festivals.
Henry B. González Convention Center
During your trip, find out what's happening in Henry B. González Convention Center, a top convention centre in San Antonio. Experience the lively festivals and great live music in this walkable area.
Alamodome
Catch an event at Alamodome during your trip to San Antonio. Experience the fascinating museums and lively festivals in this walkable area.
Top hotels in Medical Center District
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
Great
Reviewed on 29 Apr 2026
San Antonio Marriott Northwest Medical Center
Room was clean and very spacious. We arrived early and the staff member Ricky was very accommodating to us! He was very friendly and went beyond for us to get in the room early.
Reviewed on 28 Apr 2026
Courtyard by Marriott Medical Center San Antonio
Very courteous staff, quiet area, excellent bed and amenities, convenient location for medical care, easy access to shopping and great restaurants.
Reviewed on 27 Apr 2026
Drury Plaza Hotel San Antonio Riverwalk
Excellent breakfast and supper. The location is very good. The room is outdated but it is clean. Staff are very friendly and helpful.
Reviewed on 29 Apr 2026
Riverwalk Plaza
Good stay in downtown SA.
Reviewed on 29 Apr 2026
Sonesta ES Suites San Antonio Downtown Alamo Plaza
Hotel is great nice and clean great breakfast, the staff at the desk is not the nicest that’s all I got to say about that
Reviewed on 29 Apr 2026
Check Medical Center District hotel availability
Other neighbourhoods around Medical Center District
Northwest Side
If you're spending some time in Northwest Side, Huebner Oaks and Crystal Ice Palace are top sights worth seeing.
Shearer Hills - Ridgeview
While visiting Shearer Hills - Ridgeview, you might make a stop by sights like North Star Mall and San Pedro Driving Range & Par 3 Course.
Midtown
Unique features of Midtown include the river views and bars. Make a stop by San Antonio Zoo and Aquarium or The DoSeum while you're exploring the area.
La Cantera District
If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.
Tobin Hill
Tobin Hill might not have many top sights, but San Antonio Zoo and Aquarium and San Antonio Museum of Art are two attractions nearby that you can check out.
Uptown
If you're spending some time in Uptown, San Antonio Zoo and Aquarium and Marion Koogler McNay Art Museum are top sights worth seeing.
Medical Center District Travel Guide
Explore a world of travel with Expedia
- Hotels near Alamodome
- Cheap Hotels in Bandera
- Resorts in Bigfoot
- Canyon Lake Hotels
- Castroville Hotels
- Boutique Hotels in Bexar County
- Luxury Hotels in Bexar County
- B&B in Devine
- Devine Hotels
- Business Hotels in Downtown San Antonio
- Historic Hotels in Downtown San Antonio
- Hotels near Museums in Downtown San Antonio
- Hotels with Balcony in Downtown San Antonio
- Hotels with Hot Tubs in Downtown San Antonio
- Riverside Hotels in Downtown San Antonio
- Downtown San Antonio Hotels
- Hotels with Airport Transfers in Fort Sam Houston
- Garden Ridge Hotels
- Hotels Suites in Gruene
- Gruene Hotels
- Cheap Hotels in Helotes
- Hotels near Hemisfair Park
- Hotels near Henry B. González Convention Center
- Adults Only Resorts & in Hill Country
- Hotels with Connecting Rooms in Hill Country
- Hill Country Hotels
- Hotels Suites in Jefferson
- Hotels near Joint Base San Antonio
- King William Hotels
- Cheap Hotels in Kirby
- Hotels near La Villita
- Hotels near Lackland Air Force Base
- Hotels Suites in Medical Center District
- Spa Hotels in Medical Center District
- Medical Center District Hotels
- Aparthotels in Natalia
- Hotels near Natural Bridge Caverns
- Aparthotels in New Braunfels
- Hyatt Hotels in New Braunfels
- New Braunfels Hotels
- Hotels near New Braunfels Town Center at Creekside
- Treehouses in New Braunfels
- Hotels near Northside Neighborhood Park
- Luxury Hotels in Northwest San Antonio
- Cheap Hotels in Oak Creek
- Motels in Pleasanton
- Hotels near Port San Antonio
- Hotels near Randolph Air Force Base
- Hotels near River Walk
- Aparthotels in San Antonio
- Holiday Parks in San Antonio
- Aimbridge Hospitality Hotels in San Antonio
- Cheap Hotels in San Antonio
- Hotels with a Bar in San Antonio
- Hotels with Airport Transfers in San Antonio
- Hotels with Early Check-in in San Antonio
- Hotels with smoking rooms in San Antonio
- San Antonio Hotels
- Aparthotels in San Antonio Station
- Hotels near San Antonio Station
- Motels in San Antonio Station
- Town Houses in San Antonio
- Aparthotels in Schertz
- Hotels near Schlitterbahn New Braunfels Waterpark
- Cheap Hotels in Seguin
- Business Hotels in Seguin
- Hotels near Six Flags Fiesta Texas
- Aparthotels in Somerset
- Southtown Hotels
- Hotels near St. Mary's University
- Stone Oak Hotels
- Hotels near Texas Ski Ranch
- Hotels near The Rim Shopping Center
- Hotels near The Shops of La Cantera
- Hotels near Tower of the Americas
- Hotels near University of Texas at San Antonio
- Hotels near University of Texas Health and Science Center at San Antonio
- Adults Only Resorts & in Uptown
- Hotels near USAA Corporate Office Headquarters
- Car hire near Alamo Heights
- Car hire near Alamo
- Car hire near Blue Star Contemporary Art Center
- Car hire Comfort
- Car hire Devine
- Car hire near Edison
- Car hire near Jefferson
- Car hire near Lackland Air Force Base
- Car hire near Longhorn Ranch and Golf Club
- Car hire Natalia
- Car hire New Berlin
- Rental cars San Antonio Intl. airport
- Car hire Santa Clara
- Car hire near Texas Tubes
- Car hire Universal City
- Car hire near Vance Jackson
- Car hire near Vietnam War Memorial
