Medical Center District Travel Guide
San Antonio
Visit Medical Center District
Stay near popular Medical Center District attractions
Top hotels in Medical Center District
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
4431 Horizon Hill Blvd San Antonio TX
The price is ₹8,446 per night from 15 Jun to 16 Jun
₹8,446
₹9,983 total
15 Jun - 16 Jun
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (3,437 reviews)
"I chose to stay at this Laquinta's location again because it is conveniently close to where I had to do business. The staff are always courteous, helpful and available to assist me to help make my stay more pleasant. The room was clean the breakfast had delicious variety to chose from and the outside ..."
Reviewed on 14 Jun 2026
San Antonio Marriott Northwest Medical Center
3233 NW Loop 410 San Antonio TX
The price is ₹9,621 per night from 11 Jul to 12 Jul
₹9,621
₹11,432 total
11 Jul - 12 Jul
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy a free local area shuttle, room service and a 24-hour fitness centre. Our guests praise the helpful ...
8.6/10 Excellent! (1,079 reviews)
"No water on the sing no Internet bad service"
Reviewed on 13 Jun 2026
Drury Inn & Suites San Antonio Northwest Medical Center
9806 Interstate Hwy 10 W San Antonio TX
The price is ₹8,559 per night from 21 Jun to 22 Jun
₹8,559
₹10,118 total
21 Jun - 22 Jun
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,357 reviews)
"Breakfast was incredible.....Only bad thing was only 1 elevator working the whole time I was there (3 days)."
Reviewed on 14 Jun 2026
Drury Plaza Hotel San Antonio Riverwalk
105 S Saint Marys Street San Antonio TX
The price is ₹13,410 per night from 1 Jul to 2 Jul
₹13,410
₹15,852 total
1 Jul - 2 Jul
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and 2 hot tubs. Our guests praise the breakfast and the pool in their reviews. ...
9.4/10 Exceptional! (4,749 reviews)
"Great location in downtown with imediate access to Riverwalk. The property is a bit older in a regal historical type of way. Stay was great, the included breakfast a little perk, gym needs a bit of an update, and the valet was a little slow at times but is likely like this thru most high-rise hotels ..."
Reviewed on 13 Jun 2026
Hotel Valencia Riverwalk
150 E Houston St San Antonio TX
The price is ₹13,408 per night from 5 Jul to 6 Jul
₹13,408
₹18,567 total
5 Jul - 6 Jul
includes taxes & fees
Stay at this luxury hotel in San Antonio. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff and the clean rooms in ...
9.4/10 Exceptional! (2,833 reviews)
"Housekeeping didn't service the room everyday. Roof leak due to rain and humid hallways could be improved upon. Doorman/Valets were exceptional."
Reviewed on 13 Jun 2026
Riverwalk Plaza
100 Villita Street San Antonio TX
The price is ₹8,475 per night from 21 Jun to 22 Jun
₹8,475
₹10,017 total
21 Jun - 22 Jun
includes taxes & fees
Stay at this family-friendly hotel in San Antonio. Enjoy free Wi-Fi, room service and a 24-hour fitness centre. Our guests praise the restaurant and the helpful ...
8/10 Very Good! (6,520 reviews)
"Close to places around the Riverwalk. Restaurant was nice I love the mini taco which I ate twice in a row. So good. The Cafe side was ok wishing they expand the menu to a more breakfast kind not just pastries and coffee. Room was very close to the pool, clean and have toiletries inside the shower ..."
Reviewed on 14 Jun 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Medical Center District
Find the best Medical Center District areas for the activities you enjoy most. Learn more about Medical Center District
Learn more about Medical Center District
Downtown San Antonio
A scenic riverfront great entertainment and top sights from San Antonio River to Alamodome – discover Downtown San Antonio, a destination also famous for its historic sites.
Far West Side
While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.
Photo by Sarah C.
Open Photo by Sarah C.
Uptown
If you're spending some time in Uptown, San Antonio River and Marion Koogler McNay Art Museum are top sights worth seeing.
Stone Oak
Stone Oak is known for its abundant dining options, and you can plan a trip to Stone Ridge Market and Shops at Hardy Oak while you're in town.
La Cantera District
If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.
Medical Center District Travel Guide
Explore a world of travel with Expedia
- Hotels near Alamodome
- Cheap Hotels in Bandera
- Resorts in Bigfoot
- Canyon Lake Hotels
- Castroville Hotels
- Boutique Hotels in Bexar County
- Luxury Hotels in Bexar County
- B&B in Devine
- Devine Hotels
- Business Hotels in Downtown San Antonio
- Historic Hotels in Downtown San Antonio
- Hotels near Museums in Downtown San Antonio
- Hotels with Balcony in Downtown San Antonio
- Hotels with Hot Tubs in Downtown San Antonio
- Riverside Hotels in Downtown San Antonio
- Downtown San Antonio Hotels
- Hotels with Airport Transfers in Fort Sam Houston
- Garden Ridge Hotels
- Hotels Suites in Gruene
- Gruene Hotels
- Cheap Hotels in Helotes
- Hotels near Hemisfair Park
- Hotels near Henry B. González Convention Center
- Adults Only Resorts & in Hill Country
- Hotels with Connecting Rooms in Hill Country
- Hill Country Hotels
- Hotels Suites in Jefferson
- Hotels near Joint Base San Antonio
- King William Hotels
- Cheap Hotels in Kirby
- Hotels near La Villita
- Hotels near Lackland Air Force Base
- Hotels Suites in Medical Center District
- Spa Hotels in Medical Center District
- Medical Center District Hotels
- Aparthotels in Natalia
- Hotels near Natural Bridge Caverns
- Aparthotels in New Braunfels
- Hyatt Hotels in New Braunfels
- New Braunfels Hotels
- Hotels near New Braunfels Town Center at Creekside
- Treehouses in New Braunfels
- Hotels near Northside Neighborhood Park
- Luxury Hotels in Northwest San Antonio
- Cheap Hotels in Oak Creek
- Motels in Pleasanton
- Hotels near Port San Antonio
- Hotels near Randolph Air Force Base
- Hotels near River Walk
- Aparthotels in San Antonio
- Holiday Parks in San Antonio
- Aimbridge Hospitality Hotels in San Antonio
- Cheap Hotels in San Antonio
- Hotels with a Bar in San Antonio
- Hotels with Airport Transfers in San Antonio
- Hotels with Early Check-in in San Antonio
- Hotels with smoking rooms in San Antonio
- San Antonio Hotels
- Aparthotels in San Antonio Station
- Hotels near San Antonio Station
- Motels in San Antonio Station
- Town Houses in San Antonio
- Aparthotels in Schertz
- Hotels near Schlitterbahn New Braunfels Waterpark
- Cheap Hotels in Seguin
- Business Hotels in Seguin
- Hotels near Six Flags Fiesta Texas
- Aparthotels in Somerset
- Southtown Hotels
- Hotels near St. Mary's University
- Stone Oak Hotels
- Hotels near Texas Ski Ranch
- Hotels near The Rim Shopping Center
- Hotels near The Shops of La Cantera
- Hotels near Tower of the Americas
- Hotels near University of Texas at San Antonio
- Hotels near University of Texas Health and Science Center at San Antonio
- Adults Only Resorts & in Uptown
- Hotels near USAA Corporate Office Headquarters
- Car hire near Alamo Heights
- Car hire near Alamo
- Car hire near Blue Star Contemporary Art Center
- Car hire Comfort
- Car hire Devine
- Car hire near Edison
- Car hire near Jefferson
- Car hire near Lackland Air Force Base
- Car hire near Longhorn Ranch and Golf Club
- Car hire Natalia
- Car hire New Berlin
- Rental cars San Antonio Intl. airport
- Car hire Santa Clara
- Car hire near Texas Tubes
- Car hire Universal City
- Car hire near Vance Jackson
- Car hire near Vietnam War Memorial
