What is West Second Street Historic District like?

Travellers will be sure to enjoy their time in Mesa's West Second Street Historic District neighbourhood.

How many hotels can I expect to find in the West Second Street Historic District area?

Book one of Expedia's 7 hotels and other accommodation options in West Second Street Historic District and start exploring everything Mesa has to offer.

If I need to cancel my hotel reservation in West Second Street Historic District, will I receive a refund?

Yes! Most room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and receive a refund within 24 hours of booking. Add dates, click "Search", then you can filter by "fully refundable" to view the best deals in West Second Street Historic District.

What are the top things to see and do in West Second Street Historic District?

Arizona Museum of Natural History, Mesa Amphitheatre and Arizona Museum for Youth are just a few of the places to visit in and around West Second Street Historic District. Nile Theater and Lo-fi Coffee are also worth a visit when you're out sightseeing in Mesa.

The Best Hotels in West Second Street Historic District, Phoenix - 2026 Updated Prices

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Our top choices for West Second Street Historic District hotels

1. Drew 251 Mesa

West Second Street Historic District

Jeanne

₹39,223 total

includes taxes & fees

22 Sept - 23 Sept

2. Drew 253 Mesa

West Second Street Historic District

₹41,118 total

includes taxes & fees

21 Oct - 22 Oct

3. Hyatt Place Phoenix/Mesa

Mesa Grande, 3.1 km from West Second Street Historic District

greg

₹11,065 total

includes taxes & fees

28 Sept - 29 Sept

4. The Azure Hotel

Downtown, 1.7 km from West Second Street Historic District

Alison Veronica

₹5,410 total

includes taxes & fees

22 Sept - 23 Sept

5. Days Inn & Suites by Wyndham Mesa Near Phoenix

US 60 Corridor, 4.2 km from West Second Street Historic District

Kevin

₹7,264 total

includes taxes & fees

29 Sept - 30 Sept

6. Holiday Inn Express & Suites Phoenix - Airport North by IHG

14.9 km from West Second Street Historic District

Sabra

₹12,142 total

includes taxes & fees

27 Sept - 28 Sept

7. Hampton Inn & Suites Tempe/Phoenix Airport, AZ

12.6 km from West Second Street Historic District

barry

₹8,881 total

includes taxes & fees

27 Sept - 28 Sept

Premium bedding, desk, laptop workspace, blackout curtains

8. Country Inn & Suites by Radisson, Phoenix Airport, AZ

13.6 km from West Second Street Historic District

Aurilia

₹9,490 total

includes taxes & fees

4 Oct - 5 Oct

9. Springhill Suites Phoenix Scottsdale Marriott

10 km from West Second Street Historic District

Marie

₹11,963 total

includes taxes & fees

27 Sept - 28 Sept

10. Hampton Inn & Suites Phoenix Tempe

9 km from West Second Street Historic District

Kirsten Alexandra

₹7,982 total

includes taxes & fees

27 Sept - 28 Sept

11. Drury Inn & Suites Phoenix Airport

16.2 km from West Second Street Historic District

Robert

₹12,899 total

includes taxes & fees

26 Sept - 27 Sept

12. City Express by Marriott Tempe

8.8 km from West Second Street Historic District

Maria de los Angeles

₹9,327 total

includes taxes & fees

28 Sept - 29 Sept

Premium bedding, down duvets, in-room safe, desk

13. Hyatt Place Tempe Phoenix Airport

12 km from West Second Street Historic District

Michelle

₹9,537 total

includes taxes & fees

27 Sept - 28 Sept

14. Extended Stay America Premier Suites Phoenix Chandler Downto

13.4 km from West Second Street Historic District

Jordan

₹8,382 total

includes taxes & fees

27 Sept - 28 Sept

Premium bedding, pillow-top beds, desk, laptop workspace

15. Comfort Suites Scottsdale Talking Stick Entertainment District

14.2 km from West Second Street Historic District

William

₹8,953 total

includes taxes & fees

27 Sept - 28 Sept

16. Holiday Inn Express Hotel & Suites Phoenix-Airport by IHG

16.1 km from West Second Street Historic District

Michael

₹10,841 total

includes taxes & fees

27 Sept - 28 Sept

17. Hilton Garden Inn Phoenix Airport North

15.6 km from West Second Street Historic District

Aaliyah

₹10,583 total

includes taxes & fees

27 Sept - 28 Sept

18. Tempe Oasis

9.1 km from West Second Street Historic District

Ashley

₹8,563 total

includes taxes & fees

22 Sept - 23 Sept

19. Hampton Inn & Suites Phoenix/Gilbert

16.1 km from West Second Street Historic District

Michael

₹8,806 total

includes taxes & fees

27 Sept - 28 Sept

20. Hyatt House Tempe/Phoenix/University

8.9 km from West Second Street Historic District

Daniela

₹13,343 total

includes taxes & fees

28 Sept - 29 Sept

View all properties

Where to stay in West Second Street Historic District

Find the best West Second Street Historic District areas for the activities you enjoy most.

A cityscape with prominent buildings including a Chase bank and The Arizona Republic building.

Downtown Phoenix

Cheer on the Phoenix Suns at an NBA game or walk around the city’s historic precinct as you explore the state capital.

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A fountain with three horses, surrounded by red flowers and storefronts.

Old Town

Gourmet restaurants interesting history and top sights from Scottsdale Waterfront to Scottsdale Fashion Square – discover Old Town, a destination also famous for its shopping.

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A rocky hill with palm trees and a body of water.

Camelback East

You might take some time to check out the abundant dining options in Camelback East. Spend some time visiting top spots like Biltmore Fashion Park, and catch the metro at 44th Street - Washington Station or 50th Street Station to see more of the area.

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A hiker on a rocky trail with mountains in the background.

Rio Verde Foothills

If you're looking for some top things to see and do in Rio Verde Foothills and surrounding area, you can visit Golf Club Scottsdale and Tom's Thumb Trail.

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A mountainous landscape with a city in the valley below.

North Phoenix

While you're in North Phoenix, take in top sights like Reach 11 Sports Complex and jump on the metro at 19th Avenue/ Dunlap Station to see more of the city.

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