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Check prices for these dates

Tonight
16 Jan - 17 Jan
Tomorrow
17 Jan - 18 Jan
This weekend
16 Jan - 18 Jan
Next weekend
23 Jan - 25 Jan

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Our top choices for Serra Mesa hotels

3 restaurants, breakfast, lunch, dinner served; Regional cuisine

Wyndham San Diego Bayside

Wyndham San Diego Bayside
4.0 star property
9.9 km from Serra Mesa
8.4 out of 10, Very good, (5,996 reviews)
"Perfect location for cruise"
United States
blasimar
The price is ₹12,203
₹17,291 total
includes taxes & fees
19 Jan - 20 Jan
Wyndham San Diego Bayside
Lobby lounge

The Bristol Hotel San Diego

The Bristol Hotel San Diego
3.5 star property
9.9 km from Serra Mesa
8.6 out of 10, Excellent, (1,469 reviews)
"Newly remodeled rooms, clean and wonderful staff. "
United States
Zoe
The price is ₹33,455
₹38,790 total
includes taxes & fees
9 Feb - 10 Feb
The Bristol Hotel San Diego
Outdoor pool, open 7:00 AM to 10:00 PM, pool cabanas (surcharge)

San Diego Mission Bay Resort

San Diego Mission Bay Resort
4.0 star property
Mission Bay, 7.2 km from Serra Mesa
8.4 out of 10, Very good, (1,336 reviews)
"Great place for our family getaway! Loved the S’mores on the beach! "
United States
Dani
The price is ₹13,734
₹20,561 total
includes taxes & fees
2 Feb - 3 Feb
San Diego Mission Bay Resort
5 outdoor pools, a heated pool, pool umbrellas, pool loungers

Paradise Point Resort & Spa

Paradise Point Resort & Spa
4.0 star property
Mission Bay, 9.9 km from Serra Mesa
8.6 out of 10, Excellent, (2,366 reviews)
"Great facility and amenities. We look forward to taking our family back again. "
United States
Andy
The price is ₹10,998
₹17,421 total
includes taxes & fees
19 Jan - 20 Jan
Paradise Point Resort & Spa
3 outdoor pools, pool cabanas (surcharge), pool umbrellas

Sycuan Casino Resort

Sycuan Casino Resort
4.0 star property
28.8 km from Serra Mesa
9.2 out of 10, Wonderful, (1,671 reviews)
"Very clean resort. "
United States
Petrina
Sycuan Casino Resort
Exterior

Loews Coronado Bay Resort

Loews Coronado Bay Resort
4.0 star property
19.1 km from Serra Mesa
8.8 out of 10, Excellent, (1,063 reviews)
"The staff and amenities were spectacular. "
United States
Andrew
The price is ₹17,066
₹23,339 total
includes taxes & fees
8 Feb - 9 Feb
Loews Coronado Bay Resort
Poolside bar

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego
4.0 star property
Gaslamp Quarter, 10.8 km from Serra Mesa
9.0 out of 10, Wonderful, (3,225 reviews)
"Great view easy checking in fun atmosphere and good food "
United States
Sergio
The price is ₹44,615
₹56,031 total
includes taxes & fees
17 Jan - 18 Jan
Hard Rock Hotel San Diego
2 outdoor pools, a heated pool, pool loungers

The Dana on Mission Bay

The Dana on Mission Bay
3.5 star property
Mission Bay, 10.1 km from Serra Mesa
9.0 out of 10, Wonderful, (3,990 reviews)
"We had a wonderful stay!"
United States
Megan
The price is ₹14,357
₹18,578 total
includes taxes & fees
18 Jan - 19 Jan
The Dana on Mission Bay
Standard Room, 1 King Bed, Non Smoking, Bay View | Premium bedding, pillow-top beds, in-room safe, desk

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection
3.0 star property
9.3 km from Serra Mesa
9.0 out of 10, Wonderful, (912 reviews)
"Great stay. Would definitely stay again."
United States
Zoraima
The price is ₹10,362
₹12,014 total
includes taxes & fees
19 Jan - 20 Jan
The DEXTRO Little Italy, BW Premier Collection
Exterior

Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego
4.0 star property
Marina District, 10.7 km from Serra Mesa
9.0 out of 10, Wonderful, (2,882 reviews)
"Excellent stay...wonderful staff"
United States
Michelle
The price is ₹17,608
₹25,335 total
includes taxes & fees
23 Jan - 24 Jan
Manchester Grand Hyatt San Diego
Property grounds

Humphreys Half Moon Inn

Humphreys Half Moon Inn
3.5 star property
12.3 km from Serra Mesa
9.2 out of 10, Wonderful, (2,740 reviews)
"Great stay, highly recommend."
United States
Ryan
The price is ₹13,454
₹17,271 total
includes taxes & fees
2 Feb - 3 Feb
Humphreys Half Moon Inn
Restaurant

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
3.0 star property
Gaslamp Quarter, 10.6 km from Serra Mesa
9.0 out of 10, Wonderful, (1,246 reviews)
"Friendly staff, great location, excellent value overall "
United States
Maryann
The price is ₹14,375
₹16,667 total
includes taxes & fees
19 Jan - 20 Jan
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
Lobby sitting area

GreenTree Inn San Diego Mission Bay

GreenTree Inn San Diego Mission Bay
2.5 star property
Pacific Beach, 7.3 km from Serra Mesa
8.0 out of 10, Very good, (1,902 reviews)
"The staff was very nice and great location"
United States
Curtis
The price is ₹6,597
₹7,583 total
includes taxes & fees
25 Jan - 26 Jan
GreenTree Inn San Diego Mission Bay
Lobby

Embassy Suites by Hilton San Diego Bay Downtown

Embassy Suites by Hilton San Diego Bay Downtown
4.0 star property
Marina District, 10.6 km from Serra Mesa
9.0 out of 10, Wonderful, (1,577 reviews)
"Very easy vacation, convenient breakfast as well as location."
United States
Kathy
The price is ₹17,030
₹23,021 total
includes taxes & fees
30 Jan - 31 Jan
Embassy Suites by Hilton San Diego Bay Downtown
Exterior

Hampton Inn San Diego/Mission Valley

Hampton Inn San Diego/Mission Valley
2.5 star property
6.4 km from Serra Mesa
8.6 out of 10, Excellent, (1,364 reviews)
"Great breakfast-comfortable rooms-helpful staff-great location for events"
United States
bill
The price is ₹8,695
₹9,995 total
includes taxes & fees
25 Jan - 26 Jan
Hampton Inn San Diego/Mission Valley
Front of property

The Sofia Hotel

The Sofia Hotel
3.5 star property
10 km from Serra Mesa
8.6 out of 10, Excellent, (1,689 reviews)
"Great location and history to the hotel "
United States
Stephanie
The Sofia Hotel
Terrace/patio

DoubleTree by Hilton San Diego - Del Mar

DoubleTree by Hilton San Diego - Del Mar
4.0 star property
Carmel Valley, 17.4 km from Serra Mesa
8.4 out of 10, Very good, (1,972 reviews)
"We had a great stay. The room was clean, the staff friendly and helpful, and the breakfast was excellent."
United States
Christine
The price is ₹11,476
₹13,077 total
includes taxes & fees
2 Feb - 3 Feb
DoubleTree by Hilton San Diego - Del Mar
Lobby

Margaritaville Hotel San Diego Gaslamp Quarter

Margaritaville Hotel San Diego Gaslamp Quarter
4.0 star property
Gaslamp Quarter, 10.5 km from Serra Mesa
9.0 out of 10, Wonderful, (1,199 reviews)
"Perfect location in the Gaslamp District. Rooms were large & clean with friendly staff. "
United States
Ginger
The price is ₹16,041
₹22,263 total
includes taxes & fees
30 Jan - 31 Jan
Margaritaville Hotel San Diego Gaslamp Quarter
Lobby

Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld
3.0 star property
9 km from Serra Mesa
7.4 out of 10, Good, (4,131 reviews)
"Get location to the airport, safe, great staff, & overall wonderful stay"
United States
Tyler
The price is ₹7,634
₹8,775 total
includes taxes & fees
25 Jan - 26 Jan
Wyndham Garden San Diego Near SeaWorld
Exterior

Best Western Seven Seas

Best Western Seven Seas
3.0 star property
5.3 km from Serra Mesa
8.0 out of 10, Very good, (3,125 reviews)
"Breakfast was good and the staff was friendly and excellent. "
United States
Thuan
The price is ₹6,339
₹7,286 total
includes taxes & fees
25 Jan - 26 Jan
Best Western Seven Seas
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Serra Mesa

Find the best Serra Mesa areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Gaslamp Quarter featuring a bar, night scenes and street scenes

Gaslamp Quarter

The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.

Pacific Beach Park showing a beach

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Belmont Park featuring a park and rides

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Ocean Beach

With a secluded sunbathing beach, swimming-only beach, special surf beach, volleyball beach and dog beach, San Diego’s “OB” sure takes beaches seriously.

Top Serra Mesa Hotel Reviews

Sentral Gaslamp Quarter

Sentral Gaslamp Quarter

10/10 Excellent
"Everything from the great hospitality to the innovative technology. I've never heard of a washer and dryer combined into one machine! I was able to do my laundry in my room. Never been able to do that before. It was so cool 😎"
ROBIN 1-night trip
Posted 2 days ago
Sentral Gaslamp Quarter

Frequently asked questions

What's it like in Serra Mesa?
Guests are sure to enjoy their time checking out all that San Diego's Serra Mesa neighbourhood has to offer. Consider a visit to Stadium Golf Center & Batting Cages as part of your Serra Mesa travel plans.
How many hotels can I expect to find in the Serra Mesa area?
Expedia has 36 hotels and other accommodation options in Serra Mesa to choose from, making this an ideal home base for exploring the greater San Diego area.
If I need to cancel my hotel reservation in Serra Mesa, will I receive a refund?
Yes, most hotel reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review top deals in Serra Mesa.
What can I see and do in this San Diego neighbourhood?
Stadium Golf Center & Batting Cages is an attraction you might want to check out while you're in Serra Mesa. When you're sightseeing in San Diego, Convoy District and Old Cactus Garden are also worth a stop.

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