Search Hotels in Serra Mesa, San Diego

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Our top choices for Serra Mesa hotels

Berkshire Motor Hotel

Berkshire Motor Hotel
2.5 star property
North Park, 5.3 km from Serra Mesa
8.4 out of 10, Very good, (1,000 reviews)
"Clean, very chill easy check in"
United States
Susana
The price is ₹8,275
₹9,330 total
includes taxes & fees
15 Mar - 16 Mar
Berkshire Motor Hotel

Urban Boutique Hotel

Urban Boutique Hotel
3.0 star property
Little Italy, 9.3 km from Serra Mesa
8.6 out of 10, Excellent, (1,275 reviews)
"Great location for a short stay "
Canada
William
Urban Boutique Hotel

Gaslamp Plaza Suites

Gaslamp Plaza Suites
3.5 star property
Gaslamp Quarter, 10 km from Serra Mesa
9.0 out of 10, Wonderful, (1,026 reviews)
"Very friendly/kind staff, loved their enthusiasm! "
United States
Haley
The price is ₹11,413
₹12,982 total
includes taxes & fees
5 Apr - 6 Apr
Gaslamp Plaza Suites

GreenTree Inn San Diego Mission Bay

GreenTree Inn San Diego Mission Bay
2.5 star property
Pacific Beach, 7.3 km from Serra Mesa
8.0 out of 10, Very good, (1,966 reviews)
"Great stay"
United States
Lizeth
The price is ₹9,593
₹11,026 total
includes taxes & fees
18 Mar - 19 Mar
GreenTree Inn San Diego Mission Bay

La Pensione Hotel

La Pensione Hotel
3.0 star property
Little Italy, 9.3 km from Serra Mesa
8.6 out of 10, Excellent, (1,930 reviews)
"Great location and staff "
United States
morgan
La Pensione Hotel

Heritage Inn San Diego

Heritage Inn San Diego
2.0 star property
9.1 km from Serra Mesa
7.4 out of 10, Good, (1,317 reviews)
"Clean room, staff was great during check in and checking out. "
United States
Amber
The price is ₹5,486
₹6,306 total
includes taxes & fees
19 Mar - 20 Mar
Heritage Inn San Diego

Ash&9th

Ash&9th
2.0 star property
9.4 km from Serra Mesa
8.2 out of 10, Very good, (407 reviews)
"Great location as we could walk to Balboa Park, zoo, port etc."
Australia
Jocelyn
The price is ₹7,207
₹8,198 total
includes taxes & fees
7 Apr - 8 Apr
Ash&9th

Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld
3.0 star property
9 km from Serra Mesa
7.4 out of 10, Good, (4,181 reviews)
"The room was spotless and the staff were very helpful and welcoming would definitely stay here again "
United States
Raul
The price is ₹9,029
₹10,379 total
includes taxes & fees
22 Mar - 23 Mar
Wyndham Garden San Diego Near SeaWorld

SureStay Hotel by Best Western San Diego Pacific Beach

SureStay Hotel by Best Western San Diego Pacific Beach
2.5 star property
Pacific Beach, 7.3 km from Serra Mesa
8.0 out of 10, Very good, (1,551 reviews)
"Room was nice, clean, staff was friendly, "
United States
philip
The price is ₹9,719
₹10,977 total
includes taxes & fees
29 Mar - 30 Mar
SureStay Hotel by Best Western San Diego Pacific Beach

Comfort Inn Sea World Area

Comfort Inn Sea World Area
3.5 star property
8.2 km from Serra Mesa
8.6 out of 10, Excellent, (3,470 reviews)
"It was very clean and comfortable would stay again "
United States
Amparo
The price is ₹9,388
₹10,791 total
includes taxes & fees
5 Apr - 6 Apr
Comfort Inn Sea World Area

The Sofia Hotel

The Sofia Hotel
3.5 star property
10 km from Serra Mesa
8.6 out of 10, Excellent, (1,796 reviews)
"Very nice hotel with a recognition of its history in a great location."
United States
Steven
The price is ₹11,527
₹15,618 total
includes taxes & fees
7 Apr - 8 Apr
The Sofia Hotel

The Beau Hotel Gaslamp Quarter San Diego

The Beau Hotel Gaslamp Quarter San Diego
3.0 star property
Gaslamp Quarter, 9.9 km from Serra Mesa
9.0 out of 10, Wonderful, (640 reviews)
"Staff was amazing and room was spacious and clean. "
Canada
Olga
The price is ₹13,980
₹15,902 total
includes taxes & fees
6 Apr - 7 Apr
The Beau Hotel Gaslamp Quarter San Diego

Westgate Hotel

Westgate Hotel
4.5 star property
9.9 km from Serra Mesa
9.2 out of 10, Wonderful, (1,002 reviews)
"Specious room, very nice gym and spa. "
United States
Sanae Kusakabe
Westgate Hotel

Sea Harbor Hotel

Sea Harbor Hotel
2.0 star property
12.2 km from Serra Mesa
8.6 out of 10, Excellent, (1,000 reviews)
"Great location with Key West-like classic charm. "
United States
Matthew
Sea Harbor Hotel

The Bristol Hotel San Diego

The Bristol Hotel San Diego
3.5 star property
9.9 km from Serra Mesa
8.6 out of 10, Excellent, (1,519 reviews)
"Great stay, great location, great staff."
United States
Jodie
The Bristol Hotel San Diego

Comfort Inn San Diego Airport At The Harbor

Comfort Inn San Diego Airport At The Harbor
3.5 star property
11.9 km from Serra Mesa
7.8 out of 10, Good, (1,350 reviews)
"The breakfast had a good variety."
United States
Lauryn
The price is ₹9,083
₹10,259 total
includes taxes & fees
6 Apr - 7 Apr
Comfort Inn San Diego Airport At The Harbor

La Quinta Inn & Suites by Wyndham San Diego Mission Bay

La Quinta Inn & Suites by Wyndham San Diego Mission Bay
3.0 star property
North Pacific Beach, 7.4 km from Serra Mesa
8.0 out of 10, Very good, (1,490 reviews)
"Great staff, clean rooms "
United States
Hala
The price is ₹11,015
₹12,664 total
includes taxes & fees
5 Apr - 6 Apr
La Quinta Inn & Suites by Wyndham San Diego Mission Bay

Hampton Inn San Diego/Mission Valley

Hampton Inn San Diego/Mission Valley
2.5 star property
6.4 km from Serra Mesa
8.6 out of 10, Excellent, (1,456 reviews)
"Good breakfast and clean rooms. Helpful staff."
United States
Jacquelyn
The price is ₹11,432
₹13,140 total
includes taxes & fees
5 Apr - 6 Apr
Hampton Inn San Diego/Mission Valley

Best Western Yacht Harbor Hotel

Best Western Yacht Harbor Hotel
2.5 star property
11.8 km from Serra Mesa
8.4 out of 10, Very good, (1,767 reviews)
"Great breakfast, comfortable room. "
United States
Rebecca
The price is ₹9,548
₹10,956 total
includes taxes & fees
31 Mar - 1 Apr
Best Western Yacht Harbor Hotel

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
3.0 star property
Gaslamp Quarter, 10.6 km from Serra Mesa
9.0 out of 10, Wonderful, (1,291 reviews)
"A good hotel"
United States
Graer
The price is ₹13,222
₹15,330 total
includes taxes & fees
2 Apr - 3 Apr
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Serra Mesa

Find the best Serra Mesa areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Gaslamp Quarter

The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.

Ocean Beach

With a secluded sunbathing beach, swimming-only beach, special surf beach, volleyball beach and dog beach, San Diego’s “OB” sure takes beaches seriously.

Top Serra Mesa Hotel Reviews

Frequently asked questions

What's it like in Serra Mesa?
Guests are sure to enjoy their time checking out all that San Diego's Serra Mesa neighbourhood has to offer. Consider a visit to Stadium Golf Center & Batting Cages as part of your Serra Mesa travel plans.
How many hotels can I expect to find in the Serra Mesa area?
Expedia has 38 hotels and other accommodation options in Serra Mesa to choose from, making this an ideal home base for exploring the greater San Diego area.
If I need to cancel my hotel reservation in Serra Mesa, will I receive a refund?
Yes, most hotel reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review top deals in Serra Mesa.
What can I see and do in this San Diego neighbourhood?
Stadium Golf Center & Batting Cages is an attraction you might want to check out while you're in Serra Mesa. When you're sightseeing in San Diego, Convoy District and Old Cactus Garden are also worth a stop.

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