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Top Trending Hotels Near Illinois Medical District, Chicago

Hyatt House Chicago Medical/University District

3.5 star property
Illinois Medical District
9.0 out of 10, Wonderful, (1236)
"Good staff and excellent room."
Mexico
Mario Alberto Cervera
The price is ₹8,338
₹9,788 total
includes taxes & fees
17 Dec - 18 Dec
Hyatt House Chicago Medical/University District

Hampton Inn & Suites Chicago Medical District UIC

2.5 star property
Illinois Medical District
9.6 out of 10, Exceptional, (356)
"Would stay there again...loved it!"
United States
Deborah
The price is ₹7,847
₹9,212 total
includes taxes & fees
17 Dec - 18 Dec
Hampton Inn & Suites Chicago Medical District UIC

Hyatt Place Chicago Medical/University District

3.0 star property
Illinois Medical District
9.0 out of 10, Wonderful, (1411)
"Bar was great "
United States
James
The price is ₹7,955
₹9,339 total
includes taxes & fees
30 Dec - 31 Dec
Hyatt Place Chicago Medical/University District

Eurostars Magnificent Mile

4.0 star property
River North, 4.8 km from Illinois Medical District
9.0 out of 10, Wonderful, (3153)
"Amazing and will be staying again!"
United States
Angie
The price is ₹8,423
₹9,888 total
includes taxes & fees
8 Jan - 9 Jan 2026
Eurostars Magnificent Mile

DoubleTree by Hilton Chicago - Magnificent Mile

4.0 star property
Streeterville, 5.2 km from Illinois Medical District
8.8 out of 10, Excellent, (2184)
"Nice Hotel"
United States
Alan
The price is ₹8,044
₹9,442 total
includes taxes & fees
8 Jan - 9 Jan 2026
DoubleTree by Hilton Chicago - Magnificent Mile

River Hotel

4.0 star property
The Loop, 4.6 km from Illinois Medical District
8.8 out of 10, Excellent, (4852)
"Location of the Hotel is very nice and the hotel is very clean."
United States
Khaing
The price is ₹6,947
₹8,155 total
includes taxes & fees
7 Jan - 8 Jan 2026
River Hotel

Hilton Chicago/Magnificent Mile Suites

3.5 star property
Streeterville, 5.6 km from Illinois Medical District
9.0 out of 10, Wonderful, (3454)
"Great place to stay "
United States
RaShawna
The price is ₹9,519
₹11,175 total
includes taxes & fees
15 Dec - 16 Dec
Hilton Chicago/Magnificent Mile Suites

Aloft Chicago Mag Mile

3.0 star property
Streeterville, 5.2 km from Illinois Medical District
8.6 out of 10, Excellent, (2956)
"Great location and great staff!!"
United States
lynne
The price is ₹7,477
₹8,777 total
includes taxes & fees
22 Dec - 23 Dec
Aloft Chicago Mag Mile

Sable at Navy Pier Chicago, Curio Collection by Hilton

4.0 star property
Streeterville, 6.4 km from Illinois Medical District
9.4 out of 10, Exceptional, (2263)
"Smooth check in and beautiful hotel"
United States
Monique
The price is ₹8,607
₹13,168 total
includes taxes & fees
6 Jan - 7 Jan 2026
Sable at Navy Pier Chicago, Curio Collection by Hilton

Hilton Garden Inn Chicago Downtown/Magnificent Mile

3.0 star property
River North, 4.7 km from Illinois Medical District
8.4 out of 10, Very good, (4237)
"Staff were amazing."
United States
Debra
The price is ₹7,387
₹8,671 total
includes taxes & fees
18 Dec - 19 Dec
Hilton Garden Inn Chicago Downtown/Magnificent Mile

Hilton Chicago

4.0 star property
The Loop, 4.2 km from Illinois Medical District
8.4 out of 10, Very good, (2365)
"We had a great stay and will be back again."
United States
Amber
The price is ₹10,257
₹14,682 total
includes taxes & fees
27 Dec - 28 Dec
Hilton Chicago

citizenM Chicago Downtown

4.0 star property
Theatre District, 4.6 km from Illinois Medical District
9.4 out of 10, Exceptional, (4101)
"Great stay"
United States
Ericka
The price is ₹9,629
₹11,304 total
includes taxes & fees
9 Jan - 10 Jan 2026
citizenM Chicago Downtown

FOUND Hotel Chicago River North

2.0 star property
River North, 4.3 km from Illinois Medical District
8.4 out of 10, Very good, (366)
"Good place, good location, friendly staff and a great bar! "
United States
Georgi
The price is ₹5,787
₹6,794 total
includes taxes & fees
5 Jan - 6 Jan 2026
FOUND Hotel Chicago River North

Holiday Inn & Suites Chicago - Downtown by IHG

3.0 star property
West Loop, 3 km from Illinois Medical District
8.4 out of 10, Very good, (1009)
"Amazing staff clean and secure hotel "
United States
Aniyah
The price is ₹9,098
₹11,761 total
includes taxes & fees
25 Dec - 26 Dec
Holiday Inn & Suites Chicago - Downtown by IHG

Hotel Riu Plaza Chicago

4.0 star property
Streeterville, 5.1 km from Illinois Medical District
9.4 out of 10, Exceptional, (2948)
"Excellent stay great location and great rooms"
United States
Joseph
The price is ₹8,910
₹12,995 total
includes taxes & fees
17 Dec - 18 Dec
Hotel Riu Plaza Chicago

Freehand Chicago

4.0 star property
River North, 4.7 km from Illinois Medical District
8.0 out of 10, Very good, (2633)
"The room was spotless and the staff where great!"
United States
Maria
The price is ₹5,540
₹8,088 total
includes taxes & fees
6 Jan - 7 Jan 2026
Freehand Chicago

Crowne Plaza Chicago West Loop by IHG

3.5 star property
2.7 km from Illinois Medical District
9.0 out of 10, Wonderful, (1750)
"The location was great!!"
United States
Yvette
The price is ₹7,702
₹9,041 total
includes taxes & fees
14 Dec - 15 Dec
Crowne Plaza Chicago West Loop by IHG

Silversmith Hotel Chicago Downtown

4.0 star property
Theatre District, 4.3 km from Illinois Medical District
9.2 out of 10, Wonderful, (2117)
"Great hotel. Very affordable for such a perfect location."
United States
Nicholas
Silversmith Hotel Chicago Downtown

Best Western River North Hotel

2.5 star property
River North, 4.4 km from Illinois Medical District
7.8 out of 10, Good, (1025)
"Loved it will be back. "
United States
Antonio
The price is ₹7,743
₹9,089 total
includes taxes & fees
10 Dec - 11 Dec
Best Western River North Hotel

Congress Plaza Hotel

3.5 star property
The Loop, 4.2 km from Illinois Medical District
8.0 out of 10, Very good, (9647)
"Great stay comfortable bed and great location!"
United States
Kimberly Noel
The price is ₹7,948
₹9,330 total
includes taxes & fees
11 Dec - 12 Dec
Congress Plaza Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Illinois Medical District

Find the best Illinois Medical District areas for the activities you enjoy most.

Downtown Chicago

The heart of the Midwest’s glittering metropolis has many offerings, from shopping and dining to parks, museums and exciting contemporary public art.

Magnificent Mile

A dazzling array of boutiques, luxury shops, famous department stores and pleasant cafés, where shopaholics can lose themselves for hours.

The Loop

Bordered roughly by the surrounding elevated train circuit, this Chicago neighborhood has restaurants, galleries, parks and a giant silver bean.

River North

Known for its fantastic nightlife, stunning river views and popular shops, there's plenty to explore in River North. Top attractions like Merchandise Mart and Bally's Casino Chicago are major draws. Catch the metro at Merchandise Mart Station or Chicago Station (Brown Line) to see more of the city.

Theatre District

While you're in Theatre District, take in top sights like Michigan Avenue or State Street, and hop on the metro to see more of the city at Washington Station or Monroe Station (Blue Line).

Top Illinois Medical District Hotel Reviews

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Frequently asked questions

What's it like in Illinois Medical District?
Guests are sure to enjoy their time checking out all that Chicago's Illinois Medical District neighbourhood has to offer.
Where is the best place to stay in Illinois Medical District?
Based on Expedia customer reviews, Hampton Inn & Suites Chicago Medical District UIC is the highest ranked property in Illinois Medical District. This hotel is a short 15-minute walk from United Center, and it offers free breakfast and an indoor pool. Other top choices in the neighbourhood include Hyatt House Chicago Medical/University District and Hyatt Place Chicago Medical/University District.
How many hotels are there in the Illinois Medical District area?
If you're searching for places to stay in Chicago, choose from one of Expedia's 11 hotels and other accommodation options in Illinois Medical District.
If I need to cancel my hotel reservation in Illinois Medical District, will I receive a refund?
Yes, most room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If your reservation is non-refundable, you might be able to cancel it and be given a refund within 24 hours of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to view the top deals on offer in Illinois Medical District.
What can I see and do in this Chicago neighbourhood?
Don't miss favourite places to visit in the surrounding area, such as Michigan Avenue, United Center and Soldier Field. Michael Jordan Statue and National Museum of Mexican Art are also worth a visit when you're out sightseeing in Chicago.
How can I get around Illinois Medical District and the greater Chicago area?
Ready to get out and explore the city? Polk Station (Pink Line) is the closest metro station.