What's it like in Illinois Medical District?

Guests are sure to enjoy their time checking out all that Chicago's Illinois Medical District neighbourhood has to offer.

Where is the best place to stay in Illinois Medical District?

Based on Expedia customer reviews, Hampton Inn & Suites Chicago Medical District UIC is the highest ranked property in Illinois Medical District. This hotel is a short 15-minute walk from United Center, and it offers free breakfast and an indoor pool. Other top choices in the neighbourhood include Hyatt House Chicago Medical/University District and Hyatt Place Chicago Medical/University District .

How many hotels are there in the Illinois Medical District area?

If you're searching for places to stay in Chicago, choose from one of Expedia's 16 hotels and other accommodation options in Illinois Medical District.

If I need to cancel my hotel reservation in Illinois Medical District, will I receive a refund?

Yes, most room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If your reservation is non-refundable, you might be able to cancel it and be given a refund within 24 hours of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to view the top deals on offer in Illinois Medical District.

What can I see and do in this Chicago neighbourhood?

Don't miss favourite places to visit in the surrounding area, such as Soldier Field, United Center and Michigan Avenue. Malcolm X College and Michael Jordan Statue are also worth a visit when you're out sightseeing in Chicago.

How can I get around Illinois Medical District and the greater Chicago area?

Ready to get out and explore the city? Polk Station (Pink Line) is the closest metro station.

The Best Hotels in Illinois Medical District, Chicago - 2026 Updated Prices

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Our top choices for Illinois Medical District hotels

1. Hyatt Place Chicago Medical/University District

Illinois Medical District

Kirby

₹25,533 total

includes taxes & fees

27 Sept - 28 Sept

2. Hyatt House Chicago Medical/University District

Illinois Medical District

Enrique

₹26,559 total

includes taxes & fees

27 Sept - 28 Sept

3. Hampton Inn & Suites Chicago Medical District UIC

Illinois Medical District

John

₹26,063 total

includes taxes & fees

27 Sept - 28 Sept

4. Crowne Plaza Chicago West Loop by IHG

2.7 km from Illinois Medical District

Victoria

₹21,511 total

includes taxes & fees

27 Sept - 28 Sept

5. Hyatt House Chicago/West Loop-Fulton Market

2.3 km from Illinois Medical District

Joel

₹27,015 total

includes taxes & fees

27 Sept - 28 Sept

6. Hyatt Place Chicago/Downtown - The Loop

The Loop, 3.6 km from Illinois Medical District

LISA

₹25,077 total

includes taxes & fees

27 Sept - 28 Sept

7. Homewood Suites by Hilton Chicago West Loop Fulton Mkt Area

3.1 km from Illinois Medical District

Brock

₹32,651 total

includes taxes & fees

2 Oct - 3 Oct

8. Hampton Inn Chicago West Loop Fulton Market Area

3.1 km from Illinois Medical District

Rebecca

₹20,470 total

includes taxes & fees

27 Sept - 28 Sept

9. La Quinta Inn & Suites by Wyndham Chicago Downtown

The Loop, 3.6 km from Illinois Medical District

Mythli

₹25,641 total

includes taxes & fees

27 Sept - 28 Sept

10. Hilton Vacation Club Hotel Blake Chicago

The Loop, 3.8 km from Illinois Medical District

Ann

₹28,342 total

includes taxes & fees

14 Oct - 15 Oct

11. InterContinental Chicago Magnificent Mile by IHG

Magnificent Mile, 4.9 km from Illinois Medical District

Darryl Halbert

₹35,272 total

includes taxes & fees

27 Sept - 28 Sept

55-inch LCD TV with cable channels, TV, pay films

12. L7 Chicago by LOTTE

Theatre District, 4.5 km from Illinois Medical District

christina

₹32,726 total

includes taxes & fees

27 Sept - 28 Sept

13. Hilton Chicago/Magnificent Mile Suites

Streeterville, 5.6 km from Illinois Medical District

Brian

₹23,060 total

includes taxes & fees

1 Oct - 2 Oct

14. Hyatt Regency Chicago

The Loop, 4.8 km from Illinois Medical District

Whitney

₹42,632 total

includes taxes & fees

27 Sept - 28 Sept

15. Embassy Suites by Hilton Chicago Downtown River North

River North, 4.7 km from Illinois Medical District

Shweta

₹24,799 total

includes taxes & fees

27 Sept - 28 Sept

16. Hyatt Place Chicago/River North

River North, 4.4 km from Illinois Medical District

Iminique

₹27,585 total

includes taxes & fees

27 Sept - 28 Sept

Suite, 1 Bedroom, Corner | Private kitchen | Coffee/tea maker, full-sized fridge, microwave, stovetop

17. Homewood Suites by Hilton Chicago Downtown South Loop

The Loop, 4.1 km from Illinois Medical District

Pramukha

₹27,517 total

includes taxes & fees

27 Sept - 28 Sept

18. Hotel Riu Plaza Chicago

Streeterville, 5.1 km from Illinois Medical District

Sean Robert

₹30,757 total

includes taxes & fees

13 Oct - 14 Oct

19. Hyatt Centric The Loop Chicago

Theatre District, 3.9 km from Illinois Medical District

Tamika

₹30,783 total

includes taxes & fees

27 Sept - 28 Sept

Outdoor pool, pool cabanas (surcharge), pool umbrellas

20. DoubleTree by Hilton Chicago - Magnificent Mile

Streeterville, 5.3 km from Illinois Medical District

Madelyn

₹24,499 total

includes taxes & fees

27 Sept - 28 Sept

View all properties

Where to stay in Illinois Medical District

Find the best Illinois Medical District areas for the activities you enjoy most.

A cityscape with tall skyscrapers and a historic tower.

Downtown Chicago

The heart of the Midwest’s glittering metropolis has many offerings, from shopping and dining to parks, museums and exciting contemporary public art.

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A busy urban street at dusk with tall buildings, a historic tower, and pedestrians.

Magnificent Mile

A dazzling array of boutiques, luxury shops, famous department stores and pleasant cafés, where shopaholics can lose themselves for hours.

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A river with yellow boats, a bridge, and tall buildings.

The Loop

Bordered roughly by the surrounding elevated train circuit, this Chicago neighborhood has restaurants, galleries, parks and a giant silver bean.

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A large, historic building with a central tower and multiple windows, located near a body of water.

River North

Known for its fantastic nightlife, stunning river views and popular shops, there's plenty to explore in River North. Top attractions like Merchandise Mart and Bally's Casino Chicago are major draws. Catch the metro at Merchandise Mart Station or Chicago Station (Brown Line) to see more of the city.

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A river with a city skyline in the background, surrounded by green trees and grass.

Lincoln Park

Both a neighborhood and a park, this northern Chicago area has gorgeous scenery, residential streets lined with stately homes and extensive shopping and dining.

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Top Illinois Medical District Hotel Reviews

Hilton Chicago

8/10 Good

"We loved the historic aspects of the hotel. It takes up an entire city block and is packed with so much history celebrating nearly 100 years in business. However that comes with the downside of lower ceilings, older rooms, etc. the room was small but very clean and reasonable, I just prefer something more spacious than a bed 3ft from the bathroom. The hotel was absolutely beautiful and had a ton of amenities and was walkable to all of Chicago’s touristy spots which was a plus. Nina told us a bunch of fun fact and offered us water (please take it… it’s $9 a bottle at the store downstairs). Would definitely tell friends and family to stay here."

Travelodge by Wyndham Downtown Chicago

8/10 Good

"Property location is walkable to Grant Park. The hotel is in need of an upgrade but if you can get past that it is very clean and safe. Our room faced the front and even though on the 12th floor you could hear the train all night long. The curtain in the room did not completely cover the window so there was a shaft of light coming in all night. Hotels were sold out and there was no other place in our budget to check in to; and restaurants were packed. There was a major trade show in town."

Search Hotels in Illinois Medical District, Chicago

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Our top choices for Illinois Medical District hotels

1. Hyatt Place Chicago Medical/University District

2. Hyatt House Chicago Medical/University District

3. Hampton Inn & Suites Chicago Medical District UIC

4. Crowne Plaza Chicago West Loop by IHG

5. Hyatt House Chicago/West Loop-Fulton Market

6. Hyatt Place Chicago/Downtown - The Loop

7. Homewood Suites by Hilton Chicago West Loop Fulton Mkt Area

8. Hampton Inn Chicago West Loop Fulton Market Area

9. La Quinta Inn & Suites by Wyndham Chicago Downtown

10. Hilton Vacation Club Hotel Blake Chicago

11. InterContinental Chicago Magnificent Mile by IHG

12. L7 Chicago by LOTTE

13. Hilton Chicago/Magnificent Mile Suites

14. Hyatt Regency Chicago

15. Embassy Suites by Hilton Chicago Downtown River North

16. Hyatt Place Chicago/River North

17. Homewood Suites by Hilton Chicago Downtown South Loop

18. Hotel Riu Plaza Chicago

19. Hyatt Centric The Loop Chicago

20. DoubleTree by Hilton Chicago - Magnificent Mile

Where to stay in Illinois Medical District

Downtown Chicago

Magnificent Mile

The Loop

River North

Lincoln Park

Top Illinois Medical District Hotel Reviews

Hilton Chicago

Frequently asked questions

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