Illinois Medical District Trip

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Where to stay in Illinois Medical District

Find the best Illinois Medical District areas and neighborhoods for the activities you enjoy most. Learn more about Illinois Medical District
Downtown Chicago

Downtown Chicago

4 out of top 10 points of interest in this area

The heart of the Midwest’s glittering metropolis has many offerings, from shopping and dining to parks, museums and exciting contemporary public art.

Find hotels in Downtown Chicago

Top hotels in Illinois Medical District

Hotel Felix River North/Magnificent Mile

Hotel Felix River North/Magnificent Mile

4 out of 5
111 W Huron St Chicago IL
Fully refundableReserve now, pay when you stay
The price is ₹8,212 per night from 25 May to 26 May
₹8,212
₹12,651 total
25 May - 26 May
includes taxes & fees
8.2/10 Very Good! (2,689 reviews)
Place is in a great location but once you go past the lobby its very dated. Small rooms and had lots of trouble getting in touch with the front desk when we needed something.

Reviewed on 7 May 2026

Hotel Felix River North/Magnificent Mile
Congress Plaza Hotel

Congress Plaza Hotel

3.5 out of 5
520 South Michigan Avenue Chicago IL
Fully refundableReserve now, pay when you stay
The price is ₹11,853 per night from 8 May to 9 May
₹11,853
₹14,093 total
8 May - 9 May
includes taxes & fees
8/10 Very Good! (10,182 reviews)
For the price this place shouldn’t really exist anymore and the whole property redone. Food is also depressing level. If you come from London you will know.

Reviewed on 7 May 2026

Congress Plaza Hotel
River Hotel

River Hotel

4 out of 5
75 East Wacker Drive Chicago IL
Fully refundableReserve now, pay when you stay
The price is ₹13,591 per night from 25 May to 26 May
₹13,591
₹16,158 total
25 May - 26 May
includes taxes & fees
8.8/10 Excellent! (5,176 reviews)
Oh, River Hotel, how do I hate you? Let me count the ways. It was very difficult to find the hotel. It's narrow and short squished between two buildings which are much bigger. The hotels directions are terrible. All I have to say is that it's right next to the Sofitel, and I would've found it immediately. ...

Reviewed on 7 May 2026

River Hotel
See all 4,748 properties in Illinois Medical District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does an Illinois Medical District holiday package cost?
Starting from just , a holiday package is your portal to affordable travel. Custom make your Illinois Medical District trip by picking from our great range of airfares, hotels and rental cars.
How do I get a cheap travel package to Illinois Medical District?
By bundling. Hotels, rental cars and flights — combine whatever you need into an Illinois Medical District holiday package to save loads of cash. Score even more deals when you add extras such as activities or tours to your booking. But that's not the only impressive part. You have the freedom to tailor your holiday your way. We offer more than 550 partner airlines and 1,000,000 hotel options globally, so that everyone has a chance to travel and live out those holiday fantasies.
Where should I stay in Illinois Medical District?
Most travellers who visit Illinois Medical District put both University of Illinois Chicago and United Centre on their sightseeing itineraries. Why not choose a hotel that's close to these great attractions?
What are the top hotels in Illinois Medical District?
Reserve a room at Hyatt Place Chicago Medical/University District. It's one of the area's most in-demand hotels. Another great option in Illinois Medical District is Hyatt House Chicago Medical/University District.
How far in advance should I book my Illinois Medical District holiday?
Browse Expedia to compare international flights as soon as possible. In most cases, you can purchase a seat up to 12 months in advance. If you can't find your preferred air carrier, or you've left things to the last moment, don't worry. The lowest prices to Illinois Medical District sometimes occur just weeks before the date of departure.
What does an Expedia Illinois Medical District travel package include?
That depends on what kind of trip you're contemplating. Illinois Medical District holiday deals can include hotels, car rentals and flights. You can mix and match to create the package that suits your budget and style. You can also add on activities and experiences after you've booked to pick up even bigger discounts.
What should I know before booking an Illinois Medical District travel package?
A travel package can be easier on the wallet than separately booking everything you need for your getaway. For example, combine your hotels, flights and rental cars and save a packet. Whatever type of holiday you have in mind, there's bound to be a package that's perfect for you.
Can I choose my airline with an Illinois Medical District Expedia holiday package?
Most definitely. We offer more than 550 airlines around the world, so you can design your Illinois Medical District trip according to your budget and style.
If I'm not able to travel, can I cancel my Illinois Medical District holiday package?
Certainly, and we're here to help. You may be able to change or cancel your Illinois Medical District holiday package for free if you booked in the last 24 hours. But you may be charged a fee by your hotel, airline or car rental company if you booked more than 24 hours ago. If life throws you a curveball, look up our Customer Service Portal for more information.

Popular places to visit

Wrigley Field

Wrigley Field

4.5/5(40 reviews)

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Wrigley Field
Chicago Skyline, Chicago, Illinois shows amazing architecture in panoramic format

Naval Base Great Lakes

5/5(1 review)

After visiting Naval Base Great Lakes, make a plan to see the other sights and activities in North Chicago. Wander the lakeside in this family-friendly area.

Naval Base Great Lakes
Navy Pier

Navy Pier

4/5(127 reviews)

A waterfront entertainment strip with fun diversions for both young and old, with shops, restaurants and even a Ferris wheel.

Navy Pier
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.