A grand church interior with high vaulted ceilings, large columns, and a central altar.

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Our top choices for Santo Spirito hotels

1. Hotel Horto Convento

Hotel Horto Convento
4.0 star property
Santo Spirito
9.8 out of 10, Exceptional, (701 reviews)
"Staff was friendly and helpful and the establishment is clean and modern!"
Canada
Giuliana
The price is ₹12,622
₹15,424 total
includes taxes & fees
13 Aug - 14 Aug
Hotel Horto Convento

2. UNA Hotels Vittoria Firenze

UNA Hotels Vittoria Firenze
4.0 star property
Santo Spirito
8.4 out of 10, Very good, (1,001 reviews)
"Great staff and well located especially for the West Bank of the city. Slightly too far out for the city etc"
United Kingdom
Glenn
The price is ₹7,830
₹10,153 total
includes taxes & fees
30 Aug - 31 Aug
UNA Hotels Vittoria Firenze

3. Palazzo Mannaioni Suites

Palazzo Mannaioni Suites
4.0 star property
Santo Spirito
9.2 out of 10, Wonderful, (1,152 reviews)
"Lovely place, perfect location. Easy to access!"
Canada
Jeanel
The price is ₹15,840
₹18,965 total
includes taxes & fees
9 Aug - 10 Aug
Palazzo Mannaioni Suites

4. Casa Santo Nome di Gesù

Casa Santo Nome di Gesù
Santo Spirito
8.8 out of 10, Excellent, (378 reviews)
"Excellent location and wonderful staff in a unique building with an amazing history."
United Kingdom
Matthew
The price is ₹11,748
₹14,239 total
includes taxes & fees
6 Aug - 7 Aug
Casa Santo Nome di Gesù

5. La Torre Del Cestello

La Torre Del Cestello
Santo Spirito
9.0 out of 10, Wonderful, (287 reviews)
"Only thing good view and location"
United States
Karen
The price is ₹9,583
₹12,077 total
includes taxes & fees
13 Aug - 14 Aug
La Torre Del Cestello

6. Ottantotto Firenze

Ottantotto Firenze
Santo Spirito
9.6 out of 10, Exceptional, (175 reviews)
"Really beautiful property and wonderful room. Hotel is immaculately clean and we thought the hotel had been renovated to a beautiful finish. We let the hotel know we were staying for our 10 year anniversary, and a bottle of Prosecco was left in our room with a note, which was extremely kind. A great location to stay in, just across the river. Passcode is provided for front door so can come and go as please. Have booked to stay in again in October!"
United Kingdom
Samantha
The price is ₹20,791
₹24,410 total
includes taxes & fees
8 Aug - 9 Aug
Ottantotto Firenze

7. 1900 Artevita

1900 Artevita
Santo Spirito
8.8 out of 10, Excellent, (199 reviews)
"Great place, very clean and as described in the listing. It has a good AC for the summer months and I highly recommend it."
United States
Jose Felipe
The price is ₹8,843
₹11,048 total
includes taxes & fees
20 Aug - 21 Aug
1900 Artevita

8. Foresteria Valdese di Firenze - Casa per Ferie

Foresteria Valdese di Firenze - Casa per Ferie
Santo Spirito
8.8 out of 10, Excellent, (233 reviews)
"I had a lovely stay! Staff were helpful"
United States
Alloura
The price is ₹7,809
₹9,910 total
includes taxes & fees
7 Aug - 8 Aug
Foresteria Valdese di Firenze - Casa per Ferie

9. Hotel Firenze 2000

Hotel Firenze 2000
2.0 star property
Santo Spirito
7.2 out of 10, Good, (201 reviews)
"Staff very good ! Good ! clean room"
United States
Salomon
The price is ₹6,702
₹8,360 total
includes taxes & fees
16 Aug - 17 Aug
Hotel Firenze 2000

10. Home in Florence

Home in Florence
Santo Spirito
9.0 out of 10, Wonderful, (77 reviews)
"Wonderful stay again here-our second time. Beautifully clean, perfect location and friendly staff-thankyou for another lovely stay!"
United Kingdom
Victoria
The price is ₹7,533
₹9,607 total
includes taxes & fees
9 Aug - 10 Aug
Home in Florence

11. Oltrarno Splendid

Oltrarno Splendid
Santo Spirito
10.0 out of 10, Exceptional, (132 reviews)
"Amazing location, charming hotel and great breakfast"
Sweden
Carin
The price is ₹23,851
₹27,776 total
includes taxes & fees
23 Aug - 24 Aug
Oltrarno Splendid

12. Palazzo Oliveto

Palazzo Oliveto
Santo Spirito
7.6 out of 10, Good, (106 reviews)
"I really enjoyed my stay here. The host was also extremely kind and helpful."
Belgium
Mary Mariam
The price is ₹6,008
₹7,928 total
includes taxes & fees
30 Aug - 31 Aug
Palazzo Oliveto

13. Hotel Palazzo Guadagni

Hotel Palazzo Guadagni
3.0 star property
Santo Spirito
9.2 out of 10, Wonderful, (212 reviews)
"Historic vibes, clean room, nice view, helpful staff. Breakfast was included and all you can eat. Food was fresh and coffee was good."
United States
Samuel
The price is ₹23,425
₹27,088 total
includes taxes & fees
11 Aug - 12 Aug
Hotel Palazzo Guadagni

14. Drom Florence Rooms & Apartments

Drom Florence Rooms & Apartments
Santo Spirito
9.8 out of 10, Exceptional, (152 reviews)
"We had a very nice stay. Claudia was very friendly and service minded The place serves continental breakfast - and is a good idea to supplement it a little bit! Nice and quiet area, where you can walk to most things We can only recommend it Else Marie Hansen May 2026"
Denmark
Else Marie
The price is ₹9,721
₹12,014 total
includes taxes & fees
12 Aug - 13 Aug
Drom Florence Rooms & Apartments

15. La Fonderia Firenze

La Fonderia Firenze
Santo Spirito
9.6 out of 10, Exceptional, (183 reviews)
"Really nice, handy location"
United Kingdom
Kate
The price is ₹10,877
₹13,285 total
includes taxes & fees
25 Aug - 26 Aug
La Fonderia Firenze

16. AdAstra Suites

AdAstra Suites
Santo Spirito
9.8 out of 10, Exceptional, (238 reviews)
"This was our second time visiting Florence, staying at Astra. We loved the beauty of the rooms and surrounding gardens. The staff were very nice and helpful. It's the perfect blend of amenities and self-service for us. We had a B&B-style breakfast and service with 5-star rooms and vibes."
United Kingdom
Gary
The price is ₹27,436
₹31,719 total
includes taxes & fees
6 Aug - 7 Aug
AdAstra Suites

17. Torre di Bellosguardo

Torre di Bellosguardo
4.0 star property
Santo Spirito
9.0 out of 10, Wonderful, (103 reviews)
"Beautiful property and wonderful staff."
United States
Brad
The price is ₹53,682
₹60,590 total
includes taxes & fees
10 Aug - 11 Aug
Torre di Bellosguardo

18. Appartamenti degli Artisti by Mmega

Appartamenti degli Artisti by Mmega
Santo Spirito
8.6 out of 10, Excellent, (43 reviews)
"We stayed with our children and the space was excellent and the location was close enough to walk to everything. "
United States
Juliet
The price is ₹7,240
₹18,058 total
includes taxes & fees
16 Aug - 17 Aug
Appartamenti degli Artisti by Mmega

19. B&B Mia Palace

B&B Mia Palace
Santo Spirito
8.4 out of 10, Very good, (123 reviews)
"Breakfast was excellent and what a lovely host. "
United Kingdom
Wayne
The price is ₹7,355
₹9,411 total
includes taxes & fees
9 Aug - 10 Aug
B&B Mia Palace

20. Residenza D'Epoca Al Numero 8

Residenza D'Epoca Al Numero 8
Santo Spirito
9.0 out of 10, Wonderful, (165 reviews)
"Excellent place"
United States
Laura Patricia
The price is ₹8,775
₹11,192 total
includes taxes & fees
16 Aug - 17 Aug
Residenza D'Epoca Al Numero 8
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santo Spirito

Find the best Santo Spirito areas for the activities you enjoy most.

Historic Centre of Florence

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Duomo

Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Cathedral of Santa Maria del Fiore or Piazza del Duomo while you're exploring the neighbourhood.

San Giovanni

If you're spending some time in San Giovanni, Cathedral of Santa Maria del Fiore and Piazza della Signoria are top sights worth seeing.

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

Santa Croce

Santa Croce is known for its interesting museums, and you can plan a trip to Basilica of Santa Croce and Piazza Santa Croce while you're in town.

Top Santo Spirito Hotel Reviews

Find out more about Santo Spirito

Top reasons to visit Santo Spirito

  • Vibrant Piazza Santo Spirito: Experience the lively atmosphere of this charming square, perfect for relaxation and people-watching.
  • Cultural Immersion: Explore notable attractions like the San Spirito Church and historic palaces that showcase the area's rich heritage.
  • Local Wine Tours: Indulge in Tuscany's viniculture by joining wine tours that offer a taste of local flavours.
  • Quaint Streets and Romantic Charm: Wander through picturesque streets filled with friendly locals and captivating ambiance.
  • Unique Accommodations: Stay in charming hotels and bed & breakfasts that blend modern comforts with historic allure.

Find great hotels near Santo Spirito

Discover charming hotel options in Santo Spirito, Florence, where you can enjoy a delightful blend of modern comforts and historic allure. This vibrant area offers a variety of accommodations, including hotels and bed & breakfasts, perfect for travellers seeking a city-themed experience. Explore unique lodgings featuring antique furniture and enjoy the nearby attractions, such as Palazzo Ridolfi and the artistic heritage of Fra Bartolomeo, all while indulging in a pet-friendly stay.

  • The Social Hub Florence Lavagnini: Nestled approximately 2km from Santo Spirito, The Social Hub Florence Lavagnini is a vibrant 4-star hotel ideal for adventurous travellers and business professionals alike. This contemporary accommodation fosters a lively atmosphere, offering a range of adventure sports and recreational activities both on-site and nearby. Guests can enjoy modern amenities, comfortable rooms, and a communal space that encourages social interaction, making it a great choice for those looking to blend work and leisure during their stay in Florence.
  • B&B Hotel Firenze Pitti Palace al Ponte Vecchio: Located just 1km from Santo Spirito, this 4-star establishment is perfect for families seeking adventure and memorable experiences. B&B Hotel Firenze Pitti Palace al Ponte Vecchio features children’s amenities such as babysitting and childcare services, ensuring a family-friendly atmosphere. The hotel also offers exciting options like nearby bicycle rentals for exploration. With its welcoming environment and proximity to family-oriented activities, this accommodation caters well to those travelling with children.
  • Grand Hotel Cavour: Situated around 2km from Santo Spirito, the Grand Hotel Cavour combines elegance with a family-oriented approach in the heart of Florence. This 4-star hotel is noted for its superior guest rating of 9.2 and offers services tailored specifically for families, including childcare facilities. Its central location provides easy access to the city’s cultural landmarks, making it a convenient base for exploration. With spacious rooms and commendable amenities, Grand Hotel Cavour ensures a comfortable stay for families looking to immerse themselves in the rich architectural heritage of Florence.

Where to stay near Santo Spirito

Exploring Santo Spirito offers a delightful blend of culture and charm in the heart of Florence. This trendy neighbourhood, known for its lively Piazza Santo Spirito, invites travellers to immerse themselves in the Florentine Renaissance. Wander through its quaint streets, where friendly locals and romantic atmospheres create a relaxing escape. Nearby, the allure of historic sites and secluded spots awaits, making it an ideal destination for those seeking both luxury and authenticity in Tuscany.

  • Florence: The vibrant heart of Tuscany, Florence is a cultural gem renowned for its art, architecture, and history. Nestled along the banks of the Arno River, this city offers a plethora of experiences for every traveller. From the iconic Uffizi Gallery to the stunning Ponte Vecchio, Florence is a feast for the senses. The city boasts a bustling shopping area and a variety of theatres, perfect for those seeking entertainment. Don't miss the charming piazzas, where you can soak up the local atmosphere and indulge in delicious Tuscan cuisine.
  • Historic Centre of Florence: Located a mile from Santo Spirito, the Historic Centre of Florence is a UNESCO World Heritage site bursting with rich history and architectural marvels. This neighbourhood is alive with activity, especially in the warmer months, when visitors flock to its vibrant public markets and open-air theatres. Here, you can wander through picturesque piazzas and cross the famous historic bridges that connect the city. The blend of culture and commerce makes this area a must-visit for families and culture enthusiasts alike.
  • Duomo: Just 1km from Santo Spirito, the Duomo area is famed for its stunning cathedral, Santa Maria del Fiore, whose iconic dome dominates the Florence skyline. This neighbourhood is a hub for shopping, with a variety of markets and boutiques to explore, making it perfect for those looking to indulge in retail therapy. The vibrant piazzas and historic sites nearby offer plenty of opportunities for sightseeing and relaxation, making the Duomo an essential stop on your Florence itinerary.

Things to do near Santo Spirito

Shopping

Santo Spirito offers a charming shopping experience with local boutiques and artisan shops. Explore the vibrant Piazza Santo Spirito for unique souvenirs and handmade crafts. For a wider selection, head to the nearby Mercato di Sant'Ambrogio, where you can find fresh produce and traditional Tuscan products.

Recreation

Experience holistic rejuvenation at the Centro Benessere in Santo Spirito, where you can indulge in therapeutic massages and yoga classes. Explore the tranquil gardens nearby for a peaceful stroll, and immerse yourself in the local culture at the nearby artisan workshops.

Adventure

Mugello Circuit, located 27km from Santo Spirito, offers an exhilarating motor racing experience. Feel the adrenaline rush as you watch thrilling races or even participate in track days. The atmosphere is filled with excitement and a true sense of adventure, making it a must-visit for motorsport enthusiasts.

Nightlife

Explore the vibrant nightlife in Santo Spirito with a visit to Caffè Cibrèo for a relaxed atmosphere and delightful cocktails. For a lively evening, check out Kitsch for eclectic music and a diverse crowd, or head to La Ménagerie for unique drinks and a charming ambiance.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Santo Spirito

When visiting Santo Spirito, Florence, consider travelling during the cheaper months of January to February and November to save on accommodation. Book your hotel about a month in advance and aim for a Monday stay, as it's the least expensive day. Use Expedia’s search tool to filter results by budget and preferences, and look for last-minute deals. Combine your hotel booking with flights and activities for additional savings. Explore free attractions in the area and utilise public transport for economical travel around Tuscany.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around Santo Spirito are January to February and November, where the prices are slightly lower. This is in comparison to May to June and September, where prices are slightly higher.
  • The best time to book a hotel: Book your hotel around Santo Spirito about 1 month out to secure some of the cheapest prices. If you're the spontaneous type, Expedia's last minute deals and discounts are indicated via the green label below the price.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay around Santo Spirito is Monday. The most expensive day to stay around Santo Spirito is Friday.
  • Find cheap hotels on Expedia: Expedia’s search tool enables you to specify your budget, desired location, and additional preferences. You can arrange your results to display prices from lowest to highest, allowing you to identify the most affordable hotels first. Additionally, you have the option to refine your search by hotel type—selecting the Eco-certified filter will showcase sustainable and environmentally friendly hotels available for booking.
  • Consider bundling your trip: You can potentially save money by combining your hotel reservation in Santo Spirito with your flights and activities by opting for an Expedia package.

Find the best attractions near Santo Spirito

Santo Spirito in Florence is perfect for those seeking a cultural and city-themed getaway. Visitors can explore notable attractions such as Santo Spirito Square and the San Spirito Church, along with historic palaces that reflect the area's rich heritage. This vibrant neighbourhood caters to families and culture enthusiasts alike, offering a delightful mix of outdoor experiences and historical sites to enjoy during your stay.

  • Piazza di Santa Maria Novella: This lively square, located 1km from Santo Spirito, is a hub of city life, boasting beautiful architecture and vibrant cafés. It's an ideal spot to immerse yourself in Florentine culture, with the stunning church of Santa Maria Novella as its focal point.
  • Cathedral of Santa Maria del Fiore: Situated 2km away, this magnificent cathedral is renowned for its iconic dome designed by Brunelleschi. Its intricate façade and artistic treasures offer a profound glimpse into Tuscany's rich cultural heritage.
  • Uffizi Gallery: Just 1km from Santo Spirito, the Uffizi Gallery houses an impressive collection of Renaissance art. Visitors can admire masterpieces by Botticelli, Michelangelo, and Da Vinci, making it a must-visit for art enthusiasts.

Best time to go to Santo Spirito

The best time to visit Santo Spirito is dependent on what kind of holiday you are seeking. July and August are its hottest month on average. At the time of August, visitor numbers are moderately high and weather is sunny. January is its coolest month on average. At this time, visitor numbers are moderately low and weather is mostly sunny with light rain.

calendar iconCalendar Monthtemperature iconTemperaturerain iconPrecipitationmostly cloudy iconCloudinessoccupation rate iconOccupancyprice iconPricing
January41.4°F (5.2°C)Light RainMostly SunnyModerately LowSlightly Low
February43.0°F (6.1°C)Light RainMostly SunnyModerately LowSlightly Low
March47.8°F (8.8°C)Light RainMostly SunnyAverageAverage
April54.3°F (12.4°C)Light RainMostly SunnyAverageAverage
May60.4°F (15.8°C)Light RainMostly SunnyAverageSlightly High
June69.6°F (20.9°C)Light RainSunnyAverageSlightly High
July75.2°F (24.0°C)No RainSunnyModerately HighAverage
August75.2°F (24.0°C)No RainSunnyModerately HighAverage
September67.3°F (19.6°C)Light RainMostly SunnyModerately HighSlightly High
October58.8°F (14.9°C)Light RainMostly SunnyAverageAverage
November50.2°F (10.1°C)Light RainMostly SunnyAverageSlightly Low
December43.5°F (6.4°C)Light RainMostly SunnyModerately LowAverage

The nearest major airports for your trip to Santo Spirito

Flying into Santo Spirito, Florence, is convenient with several major airports nearby. Florence (FLR-Peretola) is approximately 5km away, with luxurious hotels like the 5-star Bernini Palace and Palazzo Montebello offering transportation services. Bologna (BLQ-Guglielmo Marconi) is situated 85km from Santo Spirito, featuring the Grand Hotel Majestic già Baglioni and Starhotels Excelsior, which provide shuttle services. Pisa (PSA-Galileo Galilei) lies 68km away, with notable options like the Bagni di Pisa Palace & Thermal Spa and Hotel Pisa Tower Plaza, both offering easy access to the airport. Each airport offers a range of transport options to facilitate your journey to this chaRMIng neighbourhood.

Frequently asked questions

What is Santo Spirito like?
Santo Spirito is a trendy neighbourhood known for its stunning river views. Make sure that you visit Piazza Santo Spirito and Santo Spirito Basilica as part of your Santo Spirito travel plans.
What's a favourite place to stay in Santo Spirito?
Based on our traveller data, Hotel Horto Convento is one of the top choices for your stay in Santo Spirito. This hotel is a short 14-minute walk from Piazza di Santa Maria Novella, and it offers free breakfast and a bar. Other good options for your stay in the neighbourhood include La Torre Del Cestello and UNA Hotels Vittoria Firenze.
How many hotels can I expect to find in the Santo Spirito area?
Expedia has 524 hotels and other accommodation options in Santo Spirito to choose from, making this an ideal home base for exploring the greater Florence area.
If I need to cancel my hotel reservation in Santo Spirito, will I receive a refund?
Yes, the majority of hotel reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within 24 hours of booking. Enter dates in and click on "Search", then filter by "fully refundable" to get top deals in Santo Spirito.
What can I see and do in this Florence neighbourhood?
Spend some time exploring the natural setting of Santo Spirito with a visit to Arno River and Torrigiani Garden. As you're discovering the neighbourhood, Piazza Santo Spirito and Santo Spirito Basilica are some other places worth a visit. Favourite places to visit in the surrounding area include Cathedral of Santa Maria del Fiore, Piazza di Santa Maria Novella and Piazza della Signoria. When you're sightseeing in Florence, Piazza del Duomo and Piazza del Carmine are also worth a stop.

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