Santo Spirito Travel Guide
Florence
Visit Santo Spirito
Popular places to visit
Piazza Santo Spirito
Learn about the local history of Florence with a stop at Piazza Santo Spirito. Discover the fascinating museums and notable monuments in this vibrant area.
Porta Romana
Find out about the history of Arcetri when you spend time at Porta Romana. Amble around this vibrant area's riverfront or experience its fascinating museums.
Brancacci Chapel
A dazzling array of Renaissance frescoes adorn the walls of the most famous chapel of Florence’s 750-year-old Church of Santa Maria del Carmine.
Uffizi Gallery
A visit to Florence’s famous art gallery will bring you face to face with some of the world’s best-loved masterpieces.
Ponte Vecchio
The shop-lined Ponte Vecchio over the River Arno is one of Florence’s most familiar and most romantic landmarks.
Cathedral of Santa Maria del Fiore
The magnificent dome of Santa Maria del Fiore provides the Florentine skyline with one of its most iconic outlines.
Top hotels in Santo Spirito
Hotel Horto Convento
It’s the perfect hotel for Florence - want to keep it a secret ! So it remains a haven away from the crowds of central Florence. Beautiful vicinity and lovely independent shops.
Reviewed on 24 Oct 2025
UNA Hotels Vittoria Firenze
Amazing place, love the decor!
Reviewed on 28 Jul 2025
Palazzo Mannaioni Suites
Awesome staff and a great location!
Reviewed on 14 Oct 2025
La Torre Del Cestello
I had an amazing stay! My room was great - spacious and clean - and the view from my room was incredible! I also found it to be in a great location - the walk from the train station was easy, and it’s close to the main attractions while also being far enough away to be a little quiet. I’d easily ...
Reviewed on 15 Oct 2025
Hostel Santa Monaca
Clean room , friendly staffs & very accessible to any amenities . Separate toilet , shower & lavatory specific for women only , away from male rooms & toilets . Have ample space for kitchen with utensils, tables & chairs . Highly recommended ! Love it
Reviewed on 18 Sept 2025
Foresteria Valdese di Firenze - Casa per Ferie
Very nice and interesting hotel located in Oltrarno, the artsy, lively area of Florence center, but a few blocks away from the crowds. Location is excellent! The hotel is quiet and has a wonderful history. I would stay there again.
Reviewed on 21 Oct 2025
Other neighbourhoods around Santo Spirito
San Frediano
San Frediano is known for its stunning river views, and you can plan a trip to Piazza Santo Spirito and Santo Spirito Basilica while you're in town.
Oltrarno
Oltrarno is a destination visitors seek out for its fascinating museums, picturesque gardens and beautiful river views. You might also want to check out attractions like Pitti Palace or Pitti Vintage while you're exploring the neighbourhood.
Santa Maria Novella
Enjoy the popular shops in Santa Maria Novella. The New Florence Opera House is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.
San Giovanni
If you're spending some time in San Giovanni, Uffizi Gallery and Cathedral of Santa Maria del Fiore are top sights worth seeing.
Duomo
Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Cathedral of Santa Maria del Fiore or Uffizi Gallery while you're exploring the neighbourhood.
Historic Centre of Florence
Known for its fascinating museums, stunning cathedral and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Cathedral of Santa Maria del Fiore and Uffizi Gallery are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.
