Santo Spirito Travel Guide
Florence
Visit Santo Spirito
Popular places to visit
Piazza Santo Spirito
Learn about the local history of Florence with a stop at Piazza Santo Spirito. Discover the acclaimed art galleries and stunning cathedral in this vibrant area.
Porta Romana
Porta Romana is just one of the places to see in Arcetri, so why not enjoy the other things to explore during your travels? Discover the acclaimed art galleries and churches in this vibrant area.
Brancacci Chapel
A dazzling array of Renaissance frescoes adorn the walls of the most famous chapel of Florence’s 750-year-old Church of Santa Maria del Carmine.
Uffizi Gallery
A visit to Florence’s famous art gallery will bring you face to face with some of the world’s best-loved masterpieces.
Piazza di Santa Maria Novella
After visiting Piazza di Santa Maria Novella, make a plan to see the other sights and activities in Florence. Stroll along the riverfront or experience the fascinating museums in this vibrant area.
Ponte Vecchio
The shop-lined Ponte Vecchio over the River Arno is one of Florence’s most familiar and most romantic landmarks.
Top hotels in Santo Spirito
Hotel Horto Convento
"What a historically interesting and beautiful property. My only regret is that I didn't book for longer than one night. The staff is wonderfully helpful and the room was beautiful. I had tickets to Maggio Musicale and it was an easy walk across the bridge with directions provided by staff. My only ..."
Reviewed on 21 Jun 2026
La Torre Del Cestello
"Great location in Oltrarno; clean, comfortable and well-appointed room; helpful and responsive staff. Ask for restaurant recommendations, they won’t disappoint."
Reviewed on 14 Jun 2026
Palazzo Mannaioni Suites
"Muy buena estadía! Muy confotable"
Reviewed on 21 Jun 2026
UNA Hotels Vittoria Firenze
"Great staff and well located especially for the West Bank of the city. Slightly too far out for the city etc"
Reviewed on 12 May 2026
Foresteria Valdese di Firenze - Casa per Ferie
"Excellent location, terrace room was incredibly spacious. Very clean and great customer service."
Reviewed on 21 Jun 2026
Torre di Bellosguardo
"This was by far the best hotel I have ever stayed at, as someone who travels solo often sometimes you are just looking for some peace and not having to do everything on your own. I am in awe of the property. If you are looking for privacy, story book views, and gardens this is the place to be. The ..."
Reviewed on 29 Oct 2025
Where to stay in Santo Spirito
Historic Centre of Florence
Known for its fascinating museums, stunning cathedral and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Cathedral of Santa Maria del Fiore and Piazza della Signoria are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.
Duomo
Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Cathedral of Santa Maria del Fiore or Uffizi Gallery while you're exploring the neighbourhood.
San Giovanni
If you're spending some time in San Giovanni, Uffizi Gallery and Cathedral of Santa Maria del Fiore are top sights worth seeing.
Santa Maria Novella
Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.
Santa Croce
Santa Croce is known for its interesting museums, and you can plan a trip to Basilica of Santa Croce and Piazza Santa Croce while you're in town.
