Santo Spirito Travel Guide

Florence

A grand church interior with high vaulted ceilings, large columns, and a central altar.
A stone bridge over a calm river, with historic buildings on either side.
A bustling outdoor market with white tents and various stalls.
A church with a bell tower, a circular window, and a weather vane.
A cityscape with a river, a bridge, and mountains in the background.

Stay near popular Santo Spirito attractions

A historic church with a dome and bell tower, surrounded by trees and a fountain in a public square.

Piazza Santo Spirito

9.6/10 (8 reviews)
Learn about the local history of Florence with a stop at Piazza Santo Spirito. Discover the fascinating museums and notable monuments in this vibrant area.
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Top hotels in Santo Spirito

Hotel Horto Convento

Hotel Horto Convento

4 out of 5
Viale Ariosto, 13 Florence FI
The price is ₹12,185 per night from 1 Dec to 2 Dec
₹12,185
₹14,890 total
1 Dec - 2 Dec
includes taxes & fees
Stay at this hotel in Florence. Enjoy free breakfast, free Wi-Fi and room service. Our guests praise the breakfast and the helpful staff in their reviews. Popular ...
Hotel Horto Convento
La Torre Del Cestello

La Torre Del Cestello

Via Borgo San Frediano, 8 Florence FI
The price is ₹7,330 per night from 8 Nov to 9 Nov
₹7,330
₹9,549 total
8 Nov - 9 Nov
includes taxes & fees
Stay at this residence in Florence. Enjoy free Wi-Fi, valet parking (surcharge) and daily housekeeping. Popular attractions Ponte Vecchio and Piazza del Duomo ...
9/10 Wonderful! (373 reviews)
"This was a lovely place to stay in the heart of Florence. Short walk from everywhere. Very helpful staff. Lovely room, well maintained. Not good if you need room service as that wasn’t available but restaurants and cafes are all close by. Would definitely stay there again."

Reviewed on 2 Nov 2026

La Torre Del Cestello
UNA Hotels Vittoria Firenze

UNA Hotels Vittoria Firenze

4 out of 5
Via Pisana 59 Florence FI
The price is ₹7,029 per night from 15 Nov to 16 Nov
₹7,029
₹9,219 total
15 Nov - 16 Nov
includes taxes & fees
Stay at this boutique hotel in Florence. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff in their reviews. Popular ...
8.4/10 Very good! (1,000 reviews)
"Conveniently located, easy parking, extremely friendly staff, delicious breakfast, quirky rooms."

Reviewed on 27 Oct 2026

UNA Hotels Vittoria Firenze
Palazzo Mannaioni Suites

Palazzo Mannaioni Suites

4 out of 5
Via Maffia 9 - 17r Florence FI
Fully refundableReserve now, pay when you stay
The price is ₹8,602 per night from 30 Nov to 1 Dec
₹8,602
₹10,949 total
30 Nov - 1 Dec
includes taxes & fees
Stay at this residence in Florence. Enjoy free Wi-Fi, concierge services and premium bedding. Our guests praise the helpful staff in their reviews. Popular attractions ...
9.2/10 Wonderful! (1,198 reviews)
"I absolutely love my stay in this place!! The room was beautiful with an amazing balcony view. It was clean and spacious. The people at the reception was super nice and helpful, great hospitality. The location was just perfect! It is at a walkable distance to everything."

Reviewed on 2 Nov 2026

Palazzo Mannaioni Suites
Hostel Santa Monaca

Hostel Santa Monaca

Via Santa Monaca 6 Florence FI
The price is ₹6,076 per night from 24 Nov to 25 Nov
₹6,076
₹7,533 total
24 Nov - 25 Nov
includes taxes & fees
Stay at this hostel in Florence. Enjoy free Wi-Fi, daily housekeeping and dry cleaning or laundry services. Popular attractions Ponte Vecchio and Piazza del ...
Hostel Santa Monaca
Hotel Firenze 2000

Hotel Firenze 2000

2 out of 5
Viale Raffaello Sanzio, 16 Florence FI
The price is ₹6,587 per night from 6 Dec to 7 Dec
₹6,587
₹8,201 total
6 Dec - 7 Dec
includes taxes & fees
Stay at this hotel in Florence. Enjoy free breakfast, free Wi-Fi and parking (surcharge). Popular attractions Ponte Vecchio and Piazza del Duomo are located ...
Hotel Firenze 2000
See all 525 properties in Santo Spirito
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santo Spirito

Find the best Santo Spirito areas for the activities you enjoy most.
A river with buildings on the right bank.

Historic Centre of Florence

Known for its fascinating museums, stunning cathedral and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Piazza del Duomo and Piazza di Santa Maria Novella are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.

A historic church with intricate architecture and a large open plaza with people.

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Florence.

A historic building with intricate architectural details, including a dome and ornate facades.

Duomo

Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Piazza del Duomo or Piazza di Santa Maria Novella while you're exploring the neighbourhood.

A historic bridge with arches over a river, surrounded by yellow buildings and a crowd of people.

San Giovanni

If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.

A grand cathedral with intricate architectural details, including statues and ornate decorations.

Santa Croce

Santa Croce is known for its interesting museums, and you can plan a trip to Basilica of Santa Croce and Piazza Santa Croce while you're in town.

Santo Spirito Travel Guide