Santo Spirito Trip

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to ₹100,000 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Where to stay in Santo Spirito

Find the best Santo Spirito areas and neighborhoods for the activities you enjoy most. Learn more about Santo Spirito
Historic Centre of Florence

Historic Centre of Florence

10 out of top 10 points of interest in this area

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Find hotels in Historic Centre of Florence

Top hotels in Santo Spirito

Hotel Horto Convento

Hotel Horto Convento

4 out of 5
Viale Ariosto, 13 Florence FI
The price is ₹28,420 per night from 26 May to 27 May
₹28,420
₹32,819 total
26 May - 27 May
includes taxes & fees
9.8/10 Exceptional! (646 reviews)
We got upgraded to there other hotel in the same area and it was amazing

Reviewed on 29 Apr 2026

Hotel Horto Convento
Palazzo Mannaioni Suites

Palazzo Mannaioni Suites

4 out of 5
Via Maffia 9 - 17r Florence FI
The price is ₹26,652 per night from 11 May to 12 May
₹26,652
₹30,875 total
11 May - 12 May
includes taxes & fees
9.2/10 Wonderful! (1,106 reviews)
Nice apartment with decent amenities. Bathroom are a little small for a suite. Very noisy at night especially the weekends

Reviewed on 29 Apr 2026

Palazzo Mannaioni Suites
La Torre Del Cestello

La Torre Del Cestello

Via Borgo San Frediano, 8 Florence FI
Fully refundableReserve now, pay when you stay
The price is ₹14,336 per night from 7 May to 8 May
₹14,336
₹17,327 total
7 May - 8 May
includes taxes & fees
9/10 Wonderful! (252 reviews)
Very convenient location, within walking distance of everything. Clean and spacious room with stunning view of the river. Very helpful staff.

Reviewed on 1 May 2026

La Torre Del Cestello
See all 497 properties in Santo Spirito
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santo Spirito holiday package cost?
From just . Yes, you read that right. Our Santo Spirito packages are the best way to make your dollar go further. Bundle your favourite hotels, flights and rental car and explore this wonderful destination.
How do I get a cheap travel package to Santo Spirito?
If you love scoring a bargain, bundle your bookings into a Santo Spirito holiday package. Whether you need hotels, flights, activities or rental cars, you can book everything in one place. You'll have endless choice at your fingertips as well. Expedia has more than 550 partner airlines and 1,000,000 hotels across the globe to choose from. Fly with who you want, stay in a place you like and save precious dollars — now that's the ideal getaway!
What are the top hotels in Santo Spirito?
Reserve a room at Sweet Home Campuccio, 2 Double Bedrooms In San Frediano. It's one of this area's most sought-after hotels. Another well-known option in Santo Spirito is Residenza Oltrarno, An Elegant Apartment In The Historic Centre Of Florence.
How far in advance should I book my Santo Spirito holiday?
To score cheap prices, book as soon as you can. Airlines typically release tickets, along with some of the lowest fares, up to a year in advance. Hotels, activities and car rental should also be booked early to avoid disappointment. If you were hoping for a last-minute getaway in Santo Spirito, there are always lots of great deals on Expedia. Check them out now!
What does an Expedia Santo Spirito travel package include?
Rental cars, flights and hotels, or any combination of the three — it's totally up to you. Whether you're headed to Santo Spirito with the entire family or enjoying a solo break, there's a bundle to match every budget and style. Once you've made your booking, why not add on a couple of tours as well?
What should I know before booking a Santo Spirito travel package?
Locking in all the parts of your trip together is one of the best ways to save. Combine car rentals, airfares and hotels into a neat little package. But you're not restricted to hotels. Expedia features all sorts of properties, including holiday rentals like oceanfront condos and city residences. The list goes on!
Can I choose my airline with a Santo Spirito Expedia holiday package?
Yes — and it's simple too. Expedia has access to more than 550 partner airlines all over the world. Our holiday packages give you the freedom to pick from available flights, hotels and activities that suit you.
If I'm not able to travel, can I cancel my Santo Spirito holiday package?
If your holiday plans in Santo Spirito have been upended, it's a relief to know that it is possible to cancel your booking. If you made your booking within the last 24 hours, you may be eligible for a refund. If your booking is older than that, your airline, hotel or car rental company may charge a fee. For more details, check our Customer Service Portal.

Popular places to visit

Uffizi Gallery in Florence in Italy

Uffizi Gallery

A visit to Florence’s famous art gallery will bring you face to face with some of the world’s best-loved masterpieces.

Uffizi Gallery
Cathedral of Santa Maria del Fiore

Cathedral of Santa Maria del Fiore

The magnificent dome of Santa Maria del Fiore provides the Florentine skyline with one of its most iconic outlines.

Cathedral of Santa Maria del Fiore
Piazza del Duomo

Piazza del Duomo

The beating heart of Florence is the perfect place to chill out, surrounded by some of the city’s most breathtaking architectural treasures.

Piazza del Duomo
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.