Santo Spirito Travel Guide
Florence
Visit Santo Spirito
Popular places to visit
Piazza Santo Spirito
Learn about the local history of Florence with a stop at Piazza Santo Spirito. Discover the fascinating museums and churches in this vibrant area.
Porta Romana
Porta Romana is just one of the places to see in Arcetri, so why not enjoy the other things to explore during your travels? Discover the fascinating museums and churches in this vibrant area.
Brancacci Chapel
A dazzling array of Renaissance frescoes adorn the walls of the most famous chapel of Florence’s 750-year-old Church of Santa Maria del Carmine.
Uffizi Gallery
A visit to Florence’s famous art gallery will bring you face to face with some of the world’s best-loved masterpieces.
Cathedral of Santa Maria del Fiore
The magnificent dome of Santa Maria del Fiore provides the Florentine skyline with one of its most iconic outlines.
Ponte Vecchio
The shop-lined Ponte Vecchio over the River Arno is one of Florence’s most familiar and most romantic landmarks.
Top hotels in Santo Spirito
Hotel Horto Convento
The room was great and a very nice bathroom. Breakfast was nice but not included so an extra 22E. The location wasn't terrible but not great. not near the subway and about .8 mile to the nearest subway and more then a mile to the more interesting part of town. Took a lot of taxis.
Reviewed on 6 May 2026
Palazzo Mannaioni Suites
Nice apartment with decent amenities. Bathroom are a little small for a suite. Very noisy at night especially the weekends
Reviewed on 29 Apr 2026
La Torre Del Cestello
Very convenient location, within walking distance of everything. Clean and spacious room with stunning view of the river. Very helpful staff.
Reviewed on 1 May 2026
Foresteria Valdese di Firenze - Casa per Ferie
Air conditioning doesn’t work and there’s no any instructions for how to run the air conditioning. There are lots of shops nearby and its location and public transportation are convenient. Another little problem is there no drinking water and hot water supplies.
Reviewed on 6 May 2026
Residenza D'Epoca Al Numero 8
great location and customer service was excellent.. little bit hard to find but ask restaurant on same street and they will tell you where it is exactly.
Reviewed on 25 Apr 2026
Palazzo Oliveto
Could be cleaner and more comfortable
Reviewed on 6 May 2026
Other neighbourhoods around Santo Spirito
San Frediano
San Frediano is known for its stunning river views, and you can plan a trip to Piazza Santo Spirito and Boboli Gardens while you're in town.
Oltrarno
Oltrarno is a destination visitors seek out for its fascinating museums, picturesque gardens and beautiful river views. You might also want to check out attractions like Pitti Palace or Pitti Vintage while you're exploring the neighbourhood.
Santa Maria Novella
Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.
San Giovanni
If you're spending some time in San Giovanni, Uffizi Gallery and Cathedral of Santa Maria del Fiore are top sights worth seeing.
Historic Centre of Florence
Known for its fascinating museums, stunning cathedral and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Cathedral of Santa Maria del Fiore and Uffizi Gallery are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.
Duomo
Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Cathedral of Santa Maria del Fiore or Uffizi Gallery while you're exploring the neighbourhood.
