What's it like in Serra Mesa?

Guests are sure to enjoy their time checking out all that San Diego's Serra Mesa neighbourhood has to offer. Consider a visit to Stadium Golf Center & Batting Cages as part of your Serra Mesa travel plans.

How many hotels can I expect to find in the Serra Mesa area?

Expedia has 37 hotels and other accommodation options in Serra Mesa to choose from, making this an ideal home base for exploring the greater San Diego area.

If I need to cancel my hotel reservation in Serra Mesa, will I receive a refund?

Yes, most hotel reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review top deals in Serra Mesa.

What can I see and do in this San Diego neighbourhood?

Stadium Golf Center & Batting Cages is an attraction you might want to check out while you're in Serra Mesa. When you're sightseeing in San Diego, Convoy District and Old Cactus Garden are also worth a stop.

The Best Hotels in Serra Mesa, San Diego - 2026 Updated Prices

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Our top choices for Serra Mesa hotels

3 outdoor pools, pool cabanas (surcharge), pool umbrellas

Sycuan Casino Resort

28.8 km from Serra Mesa

Petrina

Standard Room, 1 King Bed, Non Smoking, Bay View | Premium bedding, pillow-top beds, in-room safe, desk

The DEXTRO Little Italy, BW Premier Collection

9.3 km from Serra Mesa

Topeka

₹12,372 total

includes taxes & fees

22 Feb - 23 Feb

3 restaurants, breakfast, lunch, dinner served; Regional cuisine

Wyndham San Diego Bayside

9.9 km from Serra Mesa

David

₹19,429 total

includes taxes & fees

1 Mar - 2 Mar

Hyatt Regency Mission Bay Spa and Marina

Mission Bay, 10.3 km from Serra Mesa

francisco

₹21,679 total

includes taxes & fees

5 Feb - 6 Feb

Premium bedding, pillow-top beds, desk, laptop workspace

Staypineapple, Hotel Z, Gaslamp San Diego

Gaslamp Quarter, 10.4 km from Serra Mesa

Simran

₹14,658 total

includes taxes & fees

16 Feb - 17 Feb

Wyndham Garden San Diego Near SeaWorld

9 km from Serra Mesa

Anya

₹9,945 total

includes taxes & fees

8 Feb - 9 Feb

Bay Club Hotel & Marina

12.6 km from Serra Mesa

sadra

₹13,228 total

includes taxes & fees

24 Feb - 25 Feb

Crowne Plaza San Diego - Mission Valley by IHG

6.4 km from Serra Mesa

Viviann

₹11,138 total

includes taxes & fees

22 Feb - 23 Feb

Comfort Inn San Diego Old Town

Old Town San Diego, 7.9 km from Serra Mesa

Steve

₹10,389 total

includes taxes & fees

8 Feb - 9 Feb

Kings Inn San Diego

6 km from Serra Mesa

Linzee

The Encinitan Hotel & Suites

30.8 km from Serra Mesa

todd

Days Inn by Wyndham San Diego Hotel Circle

5.4 km from Serra Mesa

Melissa

₹8,448 total

includes taxes & fees

8 Feb - 9 Feb

Hard Rock Hotel San Diego

Gaslamp Quarter, 10.8 km from Serra Mesa

CINDY

₹58,329 total

includes taxes & fees

3 Feb - 4 Feb

DoubleTree by Hilton San Diego - Del Mar

Carmel Valley, 17.4 km from Serra Mesa

Felipe Ramirez

₹13,666 total

includes taxes & fees

8 Feb - 9 Feb

Best Western San Diego/Miramar Hotel

10.1 km from Serra Mesa

Sharl

₹9,003 total

includes taxes & fees

8 Feb - 9 Feb

Superior Double Room Single Use, 2 Queen Beds, Non Smoking, City View | Terrace/patio

Ash&9th

9.4 km from Serra Mesa

Guillermo

₹8,287 total

includes taxes & fees

2 Mar - 3 Mar

Loews Coronado Bay Resort

19.1 km from Serra Mesa

Taryn

₹23,777 total

includes taxes & fees

8 Feb - 9 Feb

Holiday Inn Express Mira Mesa-San Diego by IHG

12.9 km from Serra Mesa

Alejandro

₹10,680 total

includes taxes & fees

16 Feb - 17 Feb

GreenTree Inn San Diego Mission Bay

Pacific Beach, 7.3 km from Serra Mesa

Curtis

₹9,286 total

includes taxes & fees

8 Feb - 9 Feb

Best Western Plus Island Palms Hotel & Marina

12.9 km from Serra Mesa

Joseph

₹14,296 total

includes taxes & fees

22 Feb - 23 Feb

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Where to stay in Serra Mesa

Find the best Serra Mesa areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

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Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

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Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

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Gaslamp Quarter

The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.

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Ocean Beach

With a secluded sunbathing beach, swimming-only beach, special surf beach, volleyball beach and dog beach, San Diego’s “OB” sure takes beaches seriously.

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