Search Hotels in Lake Nona Medical City, Orlando

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6 Nov - 7 Nov
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Our top choices for Lake Nona Medical City hotels

Exterior

1. Aloft by Marriott Orlando Lake Nona

Aloft by Marriott Orlando Lake Nona
3.0 star property
Lake Nona Medical City
9.6 out of 10, Exceptional, (467 reviews)
"nice clean hotel, close to restaurants"
United States
Ali
The price is ₹13,132
₹14,921 total
includes taxes & fees
25 Nov - 26 Nov
Aloft by Marriott Orlando Lake Nona
A swimming pool with sun loungers and palm trees.

2. Courtyard Orlando Lake Nona

Courtyard Orlando Lake Nona
3.0 star property
Lake Nona Medical City
9.6 out of 10, Exceptional, (666 reviews)
"Great place and safe with families. There was a Halloween festival both nights so lots of people in the courtyard at Boxi Park. Music from festival was loud and didn’t stop until 11pm so FYI if you go to bed early."
United States
Lynn
The price is ₹14,738
₹16,746 total
includes taxes & fees
22 Nov - 23 Nov
Courtyard Orlando Lake Nona
A swimming pool with sun loungers and palm trees, surrounded by a modern building.

3. Residence Inn Orlando Lake Nona

Residence Inn Orlando Lake Nona
3.0 star property
Lake Nona Medical City
9.6 out of 10, Exceptional, (347 reviews)
"Hotel was very nice."
United States
Christine
The price is ₹17,037
₹19,358 total
includes taxes & fees
22 Nov - 23 Nov
Residence Inn Orlando Lake Nona
A modern restaurant with multiple dining tables and chairs, a bar area, and a television mounted on the wall.

4. Wingate by Wyndham - Orlando International Airport

Wingate by Wyndham - Orlando International Airport
3.0 star property
Airport North, 11.1 km from Lake Nona Medical City
8.8 out of 10, Excellent, (4,363 reviews)
"Great stay."
United States
Diana
The price is ₹7,468
₹8,402 total
includes taxes & fees
16 Nov - 17 Nov
Wingate by Wyndham - Orlando International Airport
An outdoor patio area with seating, a bar, and a fire feature.

5. Hyatt House Orlando Airport

Hyatt House Orlando Airport
3.5 star property
Airport North, 10.5 km from Lake Nona Medical City
9.6 out of 10, Exceptional, (2,857 reviews)
"Great place to stay."
United States
CHRIS
The price is ₹11,734
₹13,200 total
includes taxes & fees
22 Nov - 23 Nov
Hyatt House Orlando Airport
An outdoor seating area with green chairs and umbrellas, a fire pit, and a building with large windows in the background.

6. Hampton Inn & Suites Orlando Airport @ Gateway Village

Hampton Inn & Suites Orlando Airport @ Gateway Village
3.0 star property
Airport North, 10.6 km from Lake Nona Medical City
9.4 out of 10, Exceptional, (2,931 reviews)
"Clean room, friendly staff, and great breakfast options"
United States
Imran
The price is ₹10,359
₹11,654 total
includes taxes & fees
22 Nov - 23 Nov
Hampton Inn & Suites Orlando Airport @ Gateway Village
A modern hotel with a glass facade, palm trees, and a sign reading "DoubleTree by Hilton."

7. DoubleTree by Hilton Orlando Airport

DoubleTree by Hilton Orlando Airport
4.0 star property
Airport North, 11.2 km from Lake Nona Medical City
8.6 out of 10, Excellent, (2,741 reviews)
"Clean room, great area for food and nice pool."
United States
Lizette
The price is ₹9,993
₹11,243 total
includes taxes & fees
22 Nov - 23 Nov
DoubleTree by Hilton Orlando Airport
A hotel pool area with lounge chairs and umbrellas, surrounded by tall buildings and a sunset sky.

8. Drury Plaza Hotel Orlando - Disney Springs Area

Drury Plaza Hotel Orlando - Disney Springs Area
4.0 star property
22.9 km from Lake Nona Medical City
9.8 out of 10, Exceptional, (6,224 reviews)
"Best place ever to stay!"
United States
Jace
The price is ₹16,438
₹18,492 total
includes taxes & fees
25 Nov - 26 Nov
Drury Plaza Hotel Orlando - Disney Springs Area
A Holiday Inn Express building with a modern design, featuring a prominent entrance and a covered walkway.

9. Holiday Inn Express Orlando International Airport by IHG

Holiday Inn Express Orlando International Airport by IHG
2.5 star property
11.1 km from Lake Nona Medical City
9.0 out of 10, Wonderful, (2,029 reviews)
"Very close to airport Free airport shuttle and breakfast was a plus"
United States
cathy
The price is ₹9,164
₹10,310 total
includes taxes & fees
22 Nov - 23 Nov
Holiday Inn Express Orlando International Airport by IHG
A modern hotel room with a large bed, a nightstand, a drawer, a wall-mounted light, and a window with a view of trees.

10. Ramada by Wyndham Suites Orlando Airport

Ramada by Wyndham Suites Orlando Airport
3.0 star property
Airport North, 10.4 km from Lake Nona Medical City
8.2 out of 10, Very good, (6,210 reviews)
"Very nice and close to the airport"
United States
Donald
The price is ₹7,321
₹8,236 total
includes taxes & fees
30 Nov - 1 Dec
Ramada by Wyndham Suites Orlando Airport
A modern hotel lobby with a large flat-screen TV, a blue sofa, a round wooden table, and a curved reception desk.

11. Cambria Hotel Orlando Airport

Cambria Hotel Orlando Airport
3.0 star property
11.1 km from Lake Nona Medical City
9.0 out of 10, Wonderful, (2,030 reviews)
"We felt very comfortable, their staff very friendly and the food of very good quality"
United States
Jaime
The price is ₹9,372
₹10,543 total
includes taxes & fees
30 Nov - 1 Dec
Cambria Hotel Orlando Airport
A hotel with a prominent tower, palm trees, and a red roof.

12. La Quinta Inn & Suites by Wyndham Orlando Airport

La Quinta Inn & Suites by Wyndham Orlando Airport
3.0 star property
Airport North, 10.9 km from Lake Nona Medical City
7.6 out of 10, Good, (2,949 reviews)
"Great location"
United States
Cesar
The price is ₹4,553
₹5,122 total
includes taxes & fees
23 Nov - 24 Nov
La Quinta Inn & Suites by Wyndham Orlando Airport
A modern dining area with a large table, chairs, and a coffee station.

13. avid hotel Orlando International Airport by IHG

avid hotel Orlando International Airport by IHG
2.5 star property
11.2 km from Lake Nona Medical City
9.2 out of 10, Wonderful, (2,181 reviews)
"Airport shuttle was nice, the hotel was very clean"
United States
Jamie
The price is ₹8,613
₹9,690 total
includes taxes & fees
7 Dec - 8 Dec
avid hotel Orlando International Airport by IHG
A modern gym with treadmills, stationary bikes, and elliptical machines.

14. Wyndham Garden Orlando Airport

Wyndham Garden Orlando Airport
3.0 star property
Belle Isle, 11.9 km from Lake Nona Medical City
9.0 out of 10, Wonderful, (4,247 reviews)
"Excellent staff, dining options and clean property with convenient location."
United States
Linette
The price is ₹8,314
₹9,353 total
includes taxes & fees
17 Nov - 18 Nov
Wyndham Garden Orlando Airport
A modern hotel with a red carpet leading to the entrance, a wooden walkway, and a clear view of the building's facade.

15. EVEN Hotel Orlando International Airport by IHG

EVEN Hotel Orlando International Airport by IHG
3.5 star property
Airport North, 11.1 km from Lake Nona Medical City
9.4 out of 10, Exceptional, (988 reviews)
"Good hotel"
United States
Bryan
The price is ₹9,275
₹10,435 total
includes taxes & fees
7 Dec - 8 Dec
EVEN Hotel Orlando International Airport by IHG
A spacious lobby with a wooden staircase, a reception desk, and a large wall clock.

16. Country Inn & Suites by Radisson, Orlando Airport, FL

Country Inn & Suites by Radisson, Orlando Airport, FL
3.0 star property
Airport North, 11 km from Lake Nona Medical City
8.0 out of 10, Very good, (5,170 reviews)
"Wonderful stay!"
United States
ashley
The price is ₹7,308
₹8,221 total
includes taxes & fees
16 Nov - 17 Nov
Country Inn & Suites by Radisson, Orlando Airport, FL
A hotel room with two beds, a sofa, a small table, a lamp, and a framed abstract artwork on the wall.

17. Hyatt Place Orlando Airport

Hyatt Place Orlando Airport
3.0 star property
Airport North, 11 km from Lake Nona Medical City
9.0 out of 10, Wonderful, (1,959 reviews)
"Had a great stay, clean and very friendly staff will stay again"
United States
Bethanie
The price is ₹9,556
₹10,751 total
includes taxes & fees
16 Nov - 17 Nov
Hyatt Place Orlando Airport
A pool area with people swimming and relaxing.

18. Universal's Endless Summer Resort - Dockside Inn and Suites

Universal's Endless Summer Resort - Dockside Inn and Suites
3.0 star property
Florida Center, 21 km from Lake Nona Medical City
9.2 out of 10, Wonderful, (5,796 reviews)
"Great stay!"
United States
Stephanie
The price is ₹14,077
₹15,836 total
includes taxes & fees
29 Nov - 30 Nov
Universal's Endless Summer Resort - Dockside Inn and Suites
Exterior

19. Holiday Inn Orlando - I-Drive North by IHG

Holiday Inn Orlando - I-Drive North by IHG
3.0 star property
International Drive District, 21.1 km from Lake Nona Medical City
9.4 out of 10, Exceptional, (1,652 reviews)
"Location and hotel are great"
United States
Hector
The price is ₹9,079
₹10,213 total
includes taxes & fees
6 Dec - 7 Dec
Holiday Inn Orlando - I-Drive North by IHG
A modern kitchen with wooden cabinets, a central island, and a breakfast bar.

20. Hampton Inn Orlando-International Airport

Hampton Inn Orlando-International Airport
2.5 star property
Airport North, 10.8 km from Lake Nona Medical City
9.0 out of 10, Wonderful, (2,195 reviews)
"Hotel and room were clean, will stay again."
United States
Crystal
The price is ₹9,155
₹10,299 total
includes taxes & fees
24 Nov - 25 Nov
Hampton Inn Orlando-International Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Lake Nona Medical City

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Exterior
Aloft by Marriott Orlando Lake Nona
3.0 star property
9.6
Exceptional
467 reviews
View
A swimming pool with sun loungers and palm trees.
Courtyard Orlando Lake Nona
3.0 star property
9.6
Exceptional
666 reviews
View
A swimming pool with sun loungers and palm trees, surrounded by a modern building.
Residence Inn Orlando Lake Nona
3.0 star property
9.6
Exceptional
347 reviews
View
Outdoor banquet area
Rosen Shingle Creek
4.5 star property
9.6
Exceptional
4,977 reviews
View
A hotel pool area with lounge chairs and umbrellas, surrounded by tall buildings and a sunset sky.
Drury Plaza Hotel Orlando - Disney Springs Area
4.0 star property
9.8
Exceptional
6,224 reviews
View

Where to stay in Lake Nona Medical City

Find the best Lake Nona Medical City areas for the activities you enjoy most. Learn more about Lake Nona Medical City
Learn more about Lake Nona Medical City
The entrance to the Hollywood Studios area with a large sign and distinctive architecture.
Photo by Gary Burke
Open Photo by Gary Burke

Bay Lake

Exciting theme parks plentiful wildlife and top sights from Epcot® to Walt Disney World® Resort – discover Bay Lake, a destination also famous for its entertainment.

A large Ferris wheel with blue lights, surrounded by a cityscape with illuminated buildings and a tall green tower.

International Drive District

Adventure activities, iconic attractions, shopping and world-class dining destinations make this famous street one of Orlando’s most popular tourist attractions.

A roller coaster at Universal Orlando Resort, featuring a tall palm tree and a clear blue sky.
Photo by Peter Sutton
Open Photo by Peter Sutton

Florida Center

If you're spending some time in Florida Center, Universal Orlando Resort and Universal Studios Florida are top sights worth seeing.

A large Ferris wheel with blue lighting, surrounded by a parking lot and buildings.

Champions Gate

Ample dining options and top golf courses are well-reviewed features of Champions Gate. Make a stop by top sights like ChampionsGate Golf Club while you're exploring the area.

A golf course with bunkers, water hazards, and a large lake.

Reunion

The top golf courses and fun-filled water parks are top of the list for many visitors to Reunion. A stop by Reunion Resort Golf Course or Jack Nicklaus Course might round out your trip.

Top Lake Nona Medical City Hotel Reviews

Exterior
Aloft by Marriott Orlando Lake Nona

Aloft by Marriott Orlando Lake Nona

Aloft by Marriott Orlando Lake Nona
Lake Nona

10/10 Excellent

This is a great option for a night or two if you need to go to the airport and want to stop over. Very nice hotel indeed. Staff are lovely. Great bar and an impressive restaurant too. Recommended!
United Kingdom
Martin
Reviewed June 19, 2025
Aloft by Marriott Orlando Lake Nona

Frequently Asked Questions

What's it like in Lake Nona Medical City?

Lake Nona Medical City is a neighbourhood that travellers like for its restaurants.

What's the best accommodation in Lake Nona Medical City?

Based on Expedia customer reviews, Aloft Orlando Lake Nona is the highest ranked property in Lake Nona Medical City. This hotel offers a restaurant and an outdoor pool. Other favourite options in the area include Residence Inn Orlando Lake Nona and Courtyard Orlando Lake Nona.

How many hotels will I find in Lake Nona Medical City?

Expedia has 5 Lake Nona Medical City hotels and other accommodation options, and one might make a good home base for venturing out into the greater Orlando area.

If I need to cancel my hotel reservation in Lake Nona Medical City, will I receive a refund?

Yes, the majority of hotel bookings are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to still cancel and get a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to view the best deals available in Lake Nona Medical City.

What is there to do around this Orlando neighbourhood?

Eagle Creek Golf Club, USTA National Campus and Austin-Tindall Regional Park are just a few of the places to visit in and around Lake Nona Medical City. When you're sightseeing around the area, Lake Hart and Kissimmee Bay Country Club are a couple of other sights to visit.

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