The Best Hotels in Lake Nona Medical City, Orlando - 2026 Updated Prices

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Where to stay in Lake Nona Medical City

Find the best Lake Nona Medical City areas for the activities you enjoy most. Learn more about Lake Nona Medical City

The entrance to the Hollywood Studios area with a large sign and distinctive architecture.

Bay Lake

Exciting theme parks plentiful wildlife and top sights from Epcot® to Walt Disney World® Resort – discover Bay Lake, a destination also famous for its entertainment.

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A large Ferris wheel with a blue light, surrounded by a water fountain display and palm trees.

International Drive District

Adventure activities, iconic attractions, shopping and world-class dining destinations make this famous street one of Orlando’s most popular tourist attractions.

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A roller coaster at Universal Orlando Resort, featuring a tall palm tree and a clear blue sky.

Florida Center

If you're spending some time in Florida Center, Universal Orlando Resort and Universal Studios Florida are top sights worth seeing.

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A large Ferris wheel with blue lighting, surrounded by a parking lot and buildings.

Champions Gate

Ample dining options and top golf courses are well-reviewed features of Champions Gate. Make a stop by top sights like ChampionsGate Golf Club while you're exploring the area.

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A golf course with bunkers, water hazards, and a large lake.

Reunion

The top golf courses and fun-filled water parks are top of the list for many visitors to Reunion. A stop by Reunion Resort Golf Course or Jack Nicklaus Course might round out your trip.

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Top Lake Nona Medical City Hotel Reviews

Walt Disney World Dolphin

10/10 Excellent

"We really enjoyed our stay at the Dolphin. The amenities were great, it was clean and it was a 10 minute walk to Epcot. We enjoyed lunch at the restaurant by the pool, and Rosa Mexicano (our server James was a standout!). Overall, the service was wonderful everywhere. Would definitely recommend this hotel. Our only complaint was that the sign at the bus area said the first shuttle for Disney Springs arrives at 8:45 as did a staff member, but the shuttle was nowhere to be found and by 9:15 we got an Uber instead. We will definitely consider staying here again for a return trip to Disney!"

Kompose Boutique Resort at Theme Parks

10/10 Excellent

"We absolutely loved our stay at Kompose. The room felt more like a mini apartment than a hotel room. It was spacious, modern, and thoughtfully laid out with separate sleeping and living areas, a dining space, bar seating, two TVs, and plenty of room to spread out. We were genuinely surprised to find a washer/dryer combo in the room, along with laundry detergent, paper towels, dish soap, and even a fresh sponge. Those little touches made it feel like a true home away from home. The room was also incredibly quiet. We barely heard any neighboring guests, and I actually slept extremely well, which is rare for me when staying in hotels. The staff were wonderful from beginning to end. Everyone was welcoming, helpful, and genuinely friendly. Great customer service is not something you find everywhere anymore, and the team here really delivered service with a smile. The location was another huge plus. There were plenty of restaurants nearby and even a Super Walmart close by, which made everything convenient. Between the spacious room, thoughtful amenities, quiet atmosphere, great location, and outstanding service, this stay exceeded our expectations. We would absolutely stay here again."

Frequently asked questions

What's it like in Lake Nona Medical City?

Lake Nona Medical City is a neighbourhood that travellers like for its restaurants.

What's the best accommodation in Lake Nona Medical City?

Based on Expedia customer reviews, Aloft Orlando Lake Nona is the highest ranked property in Lake Nona Medical City. This hotel offers a restaurant and an outdoor pool. Other favourite options in the area include Residence Inn Orlando Lake Nona and Courtyard Orlando Lake Nona.

How many hotels will I find in Lake Nona Medical City?

Expedia has 5 Lake Nona Medical City hotels and other accommodation options, and one might make a good home base for venturing out into the greater Orlando area.

If I need to cancel my hotel reservation in Lake Nona Medical City, will I receive a refund?

Yes, the majority of hotel bookings are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to still cancel and get a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to view the best deals available in Lake Nona Medical City.

What is there to do around this Orlando neighbourhood?

Eagle Creek Golf Club, USTA National Campus and Austin-Tindall Regional Park are just a few of the places to visit in and around Lake Nona Medical City. When you're sightseeing around the area, Kissimmee Bay Country Club and Moss Park are a couple of other sights to visit.

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Our top choices for Lake Nona Medical City hotels

1. Courtyard Orlando Lake Nona

2. Residence Inn Orlando Lake Nona

3. Aloft by Marriott Orlando Lake Nona

4. Hyatt House Orlando Airport

5. Hampton Inn & Suites Orlando Airport @ Gateway Village

6. Wingate by Wyndham - Orlando International Airport

7. Wyndham Garden Orlando Airport

8. Cambria Hotel Orlando Airport

9. Ramada by Wyndham Suites Orlando Airport

10. Holiday Inn Express Orlando International Airport by IHG

11. Country Inn & Suites by Radisson, Orlando Airport, FL

12. Hyatt Place Orlando Airport

13. Fairfield Inn By Marriott Orlando Airport

14. La Quinta Inn & Suites by Wyndham Orlando Airport

15. Hampton Inn Orlando-International Airport

16. Comfort Suites Orlando International Airport

17. Sonesta Essential Orlando Airport

18. Florida Hotel & Conference Center in the Florida Mall

19. La Quinta Inn & Suites by Wyndham Orlando UCF

20. Holiday Inn Express Orlando – South Park by IHG

Where to stay in Lake Nona Medical City

Bay Lake

International Drive District

Florida Center

Champions Gate

Reunion

Top Lake Nona Medical City Hotel Reviews

Walt Disney World Dolphin

Frequently asked questions

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