Search Hotels in Serra Mesa, San Diego

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Our top choices for Serra Mesa hotels

Sycuan Casino Resort

Sycuan Casino Resort
4.0 star property
28.8 km from Serra Mesa
9.2 out of 10, Wonderful, (1,700 reviews)
"Very clean resort. "
United States
Petrina
Sycuan Casino Resort

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection
3.0 star property
9.3 km from Serra Mesa
9.0 out of 10, Wonderful, (1,004 reviews)
"Clean rooms and friendly staff"
United States
Topeka
The price is ₹10,671
₹12,372 total
includes taxes & fees
22 Feb - 23 Feb
The DEXTRO Little Italy, BW Premier Collection

Wyndham San Diego Bayside

Wyndham San Diego Bayside
4.0 star property
9.9 km from Serra Mesa
8.4 out of 10, Very good, (6,032 reviews)
"Great place to stay"
United States
David
The price is ₹13,996
₹19,429 total
includes taxes & fees
1 Mar - 2 Mar
Wyndham San Diego Bayside

Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina
4.0 star property
Mission Bay, 10.3 km from Serra Mesa
8.4 out of 10, Very good, (1,594 reviews)
"Balcony view is awesome, clean room, staff at counter and restaurant service was stunning."
United States
francisco
The price is ₹14,626
₹21,679 total
includes taxes & fees
5 Feb - 6 Feb
Hyatt Regency Mission Bay Spa and Marina

Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego
3.0 star property
Gaslamp Quarter, 10.4 km from Serra Mesa
9.4 out of 10, Exceptional, (1,004 reviews)
"Great location and stay. "
United States
Simran
The price is ₹10,349
₹14,658 total
includes taxes & fees
16 Feb - 17 Feb
Staypineapple, Hotel Z, Gaslamp San Diego

Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld
3.0 star property
9 km from Serra Mesa
7.4 out of 10, Good, (4,158 reviews)
"Good location friendly staff"
United States
Anya
The price is ₹8,652
₹9,945 total
includes taxes & fees
9 Feb - 10 Feb
Wyndham Garden San Diego Near SeaWorld

Bay Club Hotel & Marina

Bay Club Hotel & Marina
3.5 star property
12.6 km from Serra Mesa
9.2 out of 10, Wonderful, (3,355 reviews)
"We had great time and enjoyed our stay "
United States
sadra
The price is ₹11,508
₹13,228 total
includes taxes & fees
24 Feb - 25 Feb
Bay Club Hotel & Marina

Crowne Plaza San Diego - Mission Valley by IHG

Crowne Plaza San Diego - Mission Valley by IHG
3.5 star property
6.4 km from Serra Mesa
8.0 out of 10, Very good, (1,009 reviews)
"Great stay"
United States
Viviann
The price is ₹9,659
₹11,138 total
includes taxes & fees
22 Feb - 23 Feb
Crowne Plaza San Diego - Mission Valley by IHG

Comfort Inn San Diego Old Town

Comfort Inn San Diego Old Town
2.5 star property
Old Town San Diego, 7.9 km from Serra Mesa
8.2 out of 10, Very good, (1,958 reviews)
"Room was nice and clean, staff was very accomidating and friendly."
United States
Steve
The price is ₹9,038
₹10,389 total
includes taxes & fees
8 Feb - 9 Feb
Comfort Inn San Diego Old Town

Kings Inn San Diego

Kings Inn San Diego
2.5 star property
6 km from Serra Mesa
8.8 out of 10, Excellent, (3,626 reviews)
"Love the Kings Inn, always on our travel list!!"
United States
Linzee
Kings Inn San Diego

The Encinitan Hotel & Suites

The Encinitan Hotel & Suites
3.0 star property
30.8 km from Serra Mesa
8.2 out of 10, Very good, (1,355 reviews)
"Perfect location with great value. We always like to visit this hotel."
United States
todd
The Encinitan Hotel & Suites

Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle
3.0 star property
5.4 km from Serra Mesa
8.0 out of 10, Very good, (2,457 reviews)
"Very easy to check in and check out, room was clean and location was fantastic. "
United States
Melissa
The price is ₹7,350
₹8,448 total
includes taxes & fees
8 Feb - 9 Feb
Days Inn by Wyndham San Diego Hotel Circle

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego
4.0 star property
Gaslamp Quarter, 10.8 km from Serra Mesa
9.0 out of 10, Wonderful, (3,283 reviews)
"Great place to stay!"
United States
CINDY
The price is ₹46,529
₹58,329 total
includes taxes & fees
3 Feb - 4 Feb
Hard Rock Hotel San Diego

DoubleTree by Hilton San Diego - Del Mar

DoubleTree by Hilton San Diego - Del Mar
4.0 star property
Carmel Valley, 17.4 km from Serra Mesa
8.4 out of 10, Very good, (2,029 reviews)
"Nice hotel, staff is great."
United States
Felipe Ramirez
The price is ₹11,994
₹13,666 total
includes taxes & fees
8 Feb - 9 Feb
DoubleTree by Hilton San Diego - Del Mar

Best Western San Diego/Miramar Hotel

Best Western San Diego/Miramar Hotel
2.5 star property
10.1 km from Serra Mesa
7.8 out of 10, Good, (1,180 reviews)
"Great hotel. "
United States
Sharl
The price is ₹7,832
₹9,003 total
includes taxes & fees
8 Feb - 9 Feb
Best Western San Diego/Miramar Hotel

Ash&9th

Ash&9th
2.0 star property
9.4 km from Serra Mesa
8.4 out of 10, Very good, (306 reviews)
"Very nice peaceful stay "
United States
Guillermo
The price is ₹7,286
₹8,287 total
includes taxes & fees
2 Mar - 3 Mar
Ash&9th

Loews Coronado Bay Resort

Loews Coronado Bay Resort
4.0 star property
19.1 km from Serra Mesa
8.8 out of 10, Excellent, (1,073 reviews)
"Clean room, gorgeous grounds, very friendly staff "
United States
Taryn
The price is ₹17,386
₹23,777 total
includes taxes & fees
8 Feb - 9 Feb
Loews Coronado Bay Resort

Holiday Inn Express Mira Mesa-San Diego by IHG

Holiday Inn Express Mira Mesa-San Diego by IHG
2.5 star property
12.9 km from Serra Mesa
8.4 out of 10, Very good, (1,003 reviews)
"Great place to stay for a night. The bedroom was clean and comfy and the staff were courteous. The free breakfast was also great. "
United States
Alejandro
The price is ₹9,291
₹10,680 total
includes taxes & fees
16 Feb - 17 Feb
Holiday Inn Express Mira Mesa-San Diego by IHG

GreenTree Inn San Diego Mission Bay

GreenTree Inn San Diego Mission Bay
2.5 star property
Pacific Beach, 7.3 km from Serra Mesa
8.0 out of 10, Very good, (1,919 reviews)
"The staff was very nice and great location"
United States
Curtis
The price is ₹8,079
₹9,286 total
includes taxes & fees
8 Feb - 9 Feb
GreenTree Inn San Diego Mission Bay

Best Western Plus Island Palms Hotel & Marina

Best Western Plus Island Palms Hotel & Marina
3.0 star property
12.9 km from Serra Mesa
8.8 out of 10, Excellent, (1,577 reviews)
"Great place.very clean great for family would definitely stay there again."
United States
Joseph
The price is ₹12,437
₹14,296 total
includes taxes & fees
22 Feb - 23 Feb
Best Western Plus Island Palms Hotel & Marina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Serra Mesa

Find the best Serra Mesa areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Gaslamp Quarter

The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.

Ocean Beach

With a secluded sunbathing beach, swimming-only beach, special surf beach, volleyball beach and dog beach, San Diego’s “OB” sure takes beaches seriously.

Top Serra Mesa Hotel Reviews

Frequently asked questions

What's it like in Serra Mesa?
Guests are sure to enjoy their time checking out all that San Diego's Serra Mesa neighbourhood has to offer. Consider a visit to Stadium Golf Center & Batting Cages as part of your Serra Mesa travel plans.
How many hotels can I expect to find in the Serra Mesa area?
Expedia has 37 hotels and other accommodation options in Serra Mesa to choose from, making this an ideal home base for exploring the greater San Diego area.
If I need to cancel my hotel reservation in Serra Mesa, will I receive a refund?
Yes, most hotel reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review top deals in Serra Mesa.
What can I see and do in this San Diego neighbourhood?
Stadium Golf Center & Batting Cages is an attraction you might want to check out while you're in Serra Mesa. When you're sightseeing in San Diego, Convoy District and Old Cactus Garden are also worth a stop.

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