Search Hotels in Serra Mesa, San Diego

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Our top choices for Serra Mesa hotels

Sycuan Casino Resort

Sycuan Casino Resort
4.0 star property
28.8 km from Serra Mesa
9.2 out of 10, Wonderful, (1,789 reviews)
"Great stay! Extremely clean facility, friendly/attentive staff, beautiful location. Can’t wait to stay again!"
United States
Mary
Sycuan Casino Resort

Ayres Hotel San Diego South - Chula Vista

Ayres Hotel San Diego South - Chula Vista
3.0 star property
26 km from Serra Mesa
9.8 out of 10, Exceptional, (1,110 reviews)
"Great location "
United States
Irma
The price is ₹19,954
₹21,988 total
includes taxes & fees
22 Mar - 23 Mar
Ayres Hotel San Diego South - Chula Vista

Hampton Inn & Suites San Diego Airport Liberty Station

Hampton Inn & Suites San Diego Airport Liberty Station
2.5 star property
10.6 km from Serra Mesa
9.2 out of 10, Wonderful, (1,726 reviews)
"Great location for the airport stay"
United States
Christopher
The price is ₹16,108
₹18,515 total
includes taxes & fees
22 Mar - 23 Mar
Hampton Inn & Suites San Diego Airport Liberty Station

Valli Hi Motel

Valli Hi Motel
2.5 star property
28.3 km from Serra Mesa
8.4 out of 10, Very good, (1,000 reviews)
"Excelente "
Mexico
Julio
Valli Hi Motel

Best Western Americana Inn

Best Western Americana Inn
2.5 star property
28.1 km from Serra Mesa
9.0 out of 10, Wonderful, (1,238 reviews)
"Great place and service. Will definitely stay there again. "
United States
Maria
The price is ₹10,945
₹12,450 total
includes taxes & fees
26 Mar - 27 Mar
Best Western Americana Inn

Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel
3.5 star property
16.1 km from Serra Mesa
9.2 out of 10, Wonderful, (3,752 reviews)
"Nice and clean hotel when visiting the San Diego area! We have stayed here multiple times. Located next to a nice restaurant as well."
United States
Laura
The price is ₹14,925
₹16,446 total
includes taxes & fees
29 Mar - 30 Mar
Best Western Plus Marina Gateway Hotel

Holiday Inn Express San Diego Airport - Old Town by IHG

Holiday Inn Express San Diego Airport - Old Town by IHG
2.5 star property
7.9 km from Serra Mesa
9.2 out of 10, Wonderful, (1,063 reviews)
"Clean room, friendly staff, and only a 15 minute walk to Old Town. Also conveniently located close to the airport just a short shuttle drive away. "
United States
Olivia
The price is ₹12,599
₹14,482 total
includes taxes & fees
5 Apr - 6 Apr
Holiday Inn Express San Diego Airport - Old Town by IHG

Embassy Suites by Hilton San Diego La Jolla

Embassy Suites by Hilton San Diego La Jolla
4.0 star property
10.3 km from Serra Mesa
8.8 out of 10, Excellent, (1,888 reviews)
"Very clean property, nice location. Breakfast was great. "
United States
Vicki
The price is ₹16,378
₹21,465 total
includes taxes & fees
29 Mar - 30 Mar
Embassy Suites by Hilton San Diego La Jolla

SpringHill Suites by Marriott Chula Vista Eastlake

SpringHill Suites by Marriott Chula Vista Eastlake
3.5 star property
23.9 km from Serra Mesa
9.6 out of 10, Exceptional, (598 reviews)
"Excellent!"
United States
Robert
The price is ₹16,675
₹18,375 total
includes taxes & fees
29 Mar - 30 Mar
SpringHill Suites by Marriott Chula Vista Eastlake

Sheraton San Diego Resort

Sheraton San Diego Resort
4.0 star property
10.1 km from Serra Mesa
8.4 out of 10, Very good, (3,382 reviews)
"Beautiful resort! Clean, well decorated and sights are stunning - will stay again! "
Canada
Emily
The price is ₹11,580
₹17,386 total
includes taxes & fees
1 Apr - 2 Apr
Sheraton San Diego Resort

HYATT house San Diego/Sorrento Mesa

HYATT house San Diego/Sorrento Mesa
3.0 star property
11.8 km from Serra Mesa
9.0 out of 10, Wonderful, (1,000 reviews)
"Enjoyed our stay very much "
United States
Peggy Sue
The price is ₹14,451
₹16,611 total
includes taxes & fees
29 Mar - 30 Mar
HYATT house San Diego/Sorrento Mesa

San Diego Mission Bay Resort

San Diego Mission Bay Resort
4.0 star property
Mission Bay, 7.2 km from Serra Mesa
8.4 out of 10, Very good, (1,374 reviews)
"Clean room, excellent friendly staff, comfortable beds"
Canada
Shauna
The price is ₹22,140
₹30,348 total
includes taxes & fees
5 Apr - 6 Apr
San Diego Mission Bay Resort

Hampton Inn Cardiff Beach Encinitas, CA Near Del Mar

Hampton Inn Cardiff Beach Encinitas, CA Near Del Mar
3.0 star property
28 km from Serra Mesa
9.2 out of 10, Wonderful, (1,035 reviews)
"Awesome Staff, clean and great room and dog friendly! We loved the breakfast!"
United States
Marina
The price is ₹14,403
₹15,844 total
includes taxes & fees
22 Mar - 23 Mar
Hampton Inn Cardiff Beach Encinitas, CA Near Del Mar

Hilton Garden Inn San Diego Old Town/SeaWorld Area

Hilton Garden Inn San Diego Old Town/SeaWorld Area
3.0 star property
Old Town San Diego, 7.4 km from Serra Mesa
8.8 out of 10, Excellent, (1,377 reviews)
"Great location, clean room, nice atmosphere."
United States
Jon T
The price is ₹14,502
₹16,670 total
includes taxes & fees
3 Apr - 4 Apr
Hilton Garden Inn San Diego Old Town/SeaWorld Area

Old Town Inn

Old Town Inn
2.5 star property
8.1 km from Serra Mesa
9.2 out of 10, Wonderful, (1,820 reviews)
"Clean room, staff friendly and helpful, close to Old Town"
United States
Craig
Old Town Inn

The Rambler Hotel

The Rambler Hotel
3.0 star property
18.7 km from Serra Mesa
9.2 out of 10, Wonderful, (2,081 reviews)
"Great for a quick weekend stay."
United States
Jason
The price is ₹11,024
₹12,754 total
includes taxes & fees
13 Apr - 14 Apr
The Rambler Hotel

Kings Inn San Diego

Kings Inn San Diego
2.5 star property
6 km from Serra Mesa
8.8 out of 10, Excellent, (3,625 reviews)
"Enjoyed my stay here. "
United States
Gary
Kings Inn San Diego

Hilton San Diego/Del Mar

Hilton San Diego/Del Mar
4.0 star property
22.3 km from Serra Mesa
8.6 out of 10, Excellent, (1,003 reviews)
"Nice hotel, great location "
United States
Jared
The price is ₹17,395
₹19,787 total
includes taxes & fees
12 Apr - 13 Apr
Hilton San Diego/Del Mar

Best Western Plus La Mesa San Diego

Best Western Plus La Mesa San Diego
2.5 star property
14 km from Serra Mesa
8.4 out of 10, Very good, (1,000 reviews)
"Great accommodations, friendly staff, they met all our needs."
United States
Scott
The price is ₹12,127
₹13,340 total
includes taxes & fees
5 Apr - 6 Apr
Best Western Plus La Mesa San Diego

Country Inn & Suites by Radisson, San Diego North, CA

Country Inn & Suites by Radisson, San Diego North, CA
3.0 star property
11.7 km from Serra Mesa
9.0 out of 10, Wonderful, (1,442 reviews)
"Staff were friendly, my stay was comfortable. Felt safe traveling solo. "
United States
Jasmine
The price is ₹13,307
₹15,296 total
includes taxes & fees
29 Mar - 30 Mar
Country Inn & Suites by Radisson, San Diego North, CA
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Serra Mesa

Find the best Serra Mesa areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Gaslamp Quarter

The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.

Ocean Beach

With a secluded sunbathing beach, swimming-only beach, special surf beach, volleyball beach and dog beach, San Diego’s “OB” sure takes beaches seriously.

Top Serra Mesa Hotel Reviews

Frequently asked questions

What's it like in Serra Mesa?
Guests are sure to enjoy their time checking out all that San Diego's Serra Mesa neighbourhood has to offer. Consider a visit to Stadium Golf Center & Batting Cages as part of your Serra Mesa travel plans.
How many hotels can I expect to find in the Serra Mesa area?
Expedia has 38 hotels and other accommodation options in Serra Mesa to choose from, making this an ideal home base for exploring the greater San Diego area.
If I need to cancel my hotel reservation in Serra Mesa, will I receive a refund?
Yes, most hotel reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review top deals in Serra Mesa.
What can I see and do in this San Diego neighbourhood?
Stadium Golf Center & Batting Cages is an attraction you might want to check out while you're in Serra Mesa. When you're sightseeing in San Diego, Convoy District and Old Cactus Garden are also worth a stop.

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