Photo by Leonardo De Leon

Search Hotels in Otay Mesa West, San Diego

Most hotels are fully refundable. Because flexibility matters.

Save an average of 15% on thousands of hotels with Expedia Rewards

Search over 2.9 million properties and 550 airlines worldwide

Find properties with these dates

Tonight
May 14 - May 15
Tomorrow
May 15 - May 16
This weekend
May 17 - May 19
Next weekend
May 24 - May 26

Filter by

Popular filters
Popular filters
Price per night
Guest rating
Guest rating
Property class
Payment type
Payment type
Property type
Property type
Area
Area
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility
Traveller experience
Traveller experience

Top Trending Hotels Near Otay Mesa West, San Diego

Premium bedding, pillow-top beds, in-room safe, desk
Avid Hotels Tijuana Otay, an IHG Hotel
3.0 star property
9.6 out of 10, Exceptional, (731)
"Perfect. Only the parking lot required more security for cars the area is not the best or gate thanks k"
The price is ₹7,315
per night
31 May - 1 Jun
Avid Hotels Tijuana Otay, an IHG Hotel
Down duvets, in-room safe, desk, blackout curtains
Hotel Pueblo Amigo Plaza & Casino
3.5 star property
9.2 out of 10, Wonderful, (1003)
"Clean"
The price is ₹12,553
per night
3 Jun - 4 Jun
Hotel Pueblo Amigo Plaza & Casino
Breakfast, lunch, dinner served; American cuisine
Best Western Plus Marina Gateway Hotel
3.5 star property
9.0 out of 10, Wonderful, (2496)
"I enjoyed this hotel in National City. It had free parking and was right next to the freeway so easy to get to San Diego. The room was clean. The hotel also has a nice outdoor pool. I only experienced the loud music from the neighboring restaurant for 1 night, but i knew going in and asked for a quieter room during check in. The hotel is also located next to an In n Out and a Chik Fil A which is super convenient. Overall I would recommend booking this hotel."
The price is ₹13,452
per night
27 May - 28 May
Best Western Plus Marina Gateway Hotel
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free
View from room
The Rambler Motel
3.0 star property
9.0 out of 10, Wonderful, (1714)
"This is a clean renovated place. Beds are comfortable. Rooms are kinda small but still a nice place. "
The price is ₹10,437
per night
21 May - 22 May
The Rambler Motel
Property entrance
Hotel Ticuán
3.5 star property
9.0 out of 10, Wonderful, (1716)
"Everything thank you nice hotel"
The price is ₹7,700
per night
16 May - 17 May
Hotel Ticuán
Terrace/patio
Quartz Hotel & SPA
4.5 star property
9.0 out of 10, Wonderful, (1007)
"The staff was super friendly! We loved the spa and the couple's massage. It was very relaxing. The food was delicious, and our server was excellent. We will be staying here again."
The price is ₹13,573
per night
2 Jun - 3 Jun
Quartz Hotel & SPA
Outdoor pool
Grand Hotel Tijuana
3.5 star property
8.8 out of 10, Excellent, (2465)
"The staff is really nice. And they had nice views of the city and the golf course. Is very convenient to everything also"
The price is ₹10,098
per night
3 Jun - 4 Jun
Grand Hotel Tijuana
Reception
Best Western Americana Inn
2.5 star property
8.8 out of 10, Excellent, (1003)
"Great breakfast in the morning. Clean. Nice location. Quite. Friendly staff. "
The price is ₹9,479
per night
27 May - 28 May
Best Western Americana Inn
Exterior
Loews Coronado Bay Resort
4.0 star property
8.6 out of 10, Excellent, (1054)
"A quiet and peaceful place to relax"
The price is ₹18,286
per night
27 May - 28 May
Loews Coronado Bay Resort
Terrace/patio
Hotel Grand One Plaza
3.0 star property
8.4 out of 10, Very good, (598)
"A little noise, but staff very friendly and accommodating "
The price is ₹4,344
per night
15 May - 16 May
Hotel Grand One Plaza
Exterior
La Quinta Inn by Wyndham San Diego Chula Vista
2.5 star property
8.4 out of 10, Very good, (1000)
"The property is close to the freeway entrance."
The price is ₹10,233
per night
19 May - 20 May
La Quinta Inn by Wyndham San Diego Chula Vista
Bar (on property)
Real Inn Tijuana by Camino Real Hotels
4.5 star property
8.2 out of 10, Very good, (1492)
"Great as always!"
The price is ₹9,612
per night
14 Jun - 15 Jun
Real Inn Tijuana by Camino Real Hotels
Reception
One Tijuana Otay
3.0 star property
8.2 out of 10, Very good, (1007)
"Perfect location for a quick stay"
The price is ₹8,350
per night
17 May - 18 May
One Tijuana Otay
Outdoor pool
Hotel Lucerna Tijuana
4.5 star property
8.2 out of 10, Very good, (1002)
"View was amazing"
The price is ₹13,421
per night
2 Jun - 3 Jun
Hotel Lucerna Tijuana
Daily continental breakfast (USD 6.95 per person)
Hercor Hotel - Urban Boutique
3.0 star property
8.2 out of 10, Very good, (1003)
"Very quiet. "
The price is ₹8,443
per night
30 May - 31 May
Hercor Hotel - Urban Boutique
Outdoor pool
Fiesta Inn Tijuana Otay
3.5 star property
8.2 out of 10, Very good, (1001)
"Excellent property! Clean, safe area, nice mall nearby"
The price is ₹10,229
per night
25 May - 26 May
Fiesta Inn Tijuana Otay
Standard Double Room, 2 Double Beds | Premium bedding, in-room safe, desk, blackout curtains
Hotel Principado Tijuana Zona Aeropuerto
3.0 star property
8.0 out of 10, Very good, (999)
"Its ok"
The price is ₹6,954
per night
15 May - 16 May
Hotel Principado Tijuana Zona Aeropuerto
3 outdoor pools
Rosarito Beach Hotel
3.0 star property
7.8 out of 10, Good, (1001)
"Room was spacious and clean booked one of the suites Staff was great and helpful during our whole stay There's a lot you can do walking distance from the hotel "
The price is ₹8,446
per night
21 May - 22 May
Rosarito Beach Hotel
Front of property
MISION 11
3.0 star property
7.8 out of 10, Good, (390)
"Clean parking lot is a storage"
The price is ₹5,851
per night
15 May - 16 May
MISION 11
Reception
Ibis Tijuana Zona Rio
3.0 star property
7.8 out of 10, Good, (1106)
"."
The price is ₹8,048
per night
9 Jun - 10 Jun
Ibis Tijuana Zona Rio
Don't see what you're looking for?
See all available properties in Otay Mesa West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Otay Mesa West

Hotels in top San Diego neighborhoods Learn more about Otay Mesa West
Default Image

Downtown San Diego

2 out of top 10 points of interest in this area
4.5/5(138 area reviews)

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and USS Midway Museum are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Find hotels in Downtown San Diego

Otay Mesa West hotels information

Number of reviews
Accommodation
 hotels
Lowest Price
Highest Price

Frequently asked questions

What is Otay Mesa West like?

Otay Mesa West is a neighbourhood that travellers like for its cathedral.

How many hotels are there in the Otay Mesa West area?

When you want to find places to stay in San Diego, start by booking one of Expedia's 5 hotels and other accommodation options in Otay Mesa West.

If I need to cancel my hotel reservation in Otay Mesa West, will I receive a refund?

Yes! The majority of room reservations are refundable if you cancel before the hotel’s cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of your booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to review top deals in Otay Mesa West.

What is there to do around this San Diego neighbourhood?

A few places to visit in the area around Otay Mesa West include San Ysidro Border Crossing, Las Americas Premium Outlets and Aquatica. While you're out sightseeing in San Diego, make sure that you visit other sights such as Tijuana Customs - Garita El Chaparral or North Island Credit Union Amphitheatre.

How can I get around Otay Mesa West and the greater San Diego area?

Ready to get out and explore the city? Iris Avenue Trolley Station is the closest metro station.

Otay Mesa West Hotel Reviews

Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

5/5 Excellent
"Stayed at this property over 20 times and it never disappoints!"
A verified traveller stayed at Manchester Grand Hyatt San Diego
Posted 5 hours ago
Manchester Grand Hyatt San Diego