What is Otay Mesa West like?

Otay Mesa West is a neighbourhood that travellers like for its cathedral.

If I need to cancel my hotel reservation in Otay Mesa West, will I receive a refund?

Yes! The majority of room reservations are refundable if you cancel before the hotel’s cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of your booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to review top deals in Otay Mesa West.

What is there to do around this San Diego neighbourhood?

A few places to visit in the area around Otay Mesa West include San Ysidro Border Crossing, Las Americas Premium Outlets and Sesame Place San Diego. While you're out sightseeing in San Diego, make sure that you visit other sights such as Tijuana Customs - Garita El Chaparral or North Island Credit Union Amphitheatre.

How can I get around Otay Mesa West and the greater San Diego area?

Ready to get out and explore the city? Iris Avenue Trolley Station is the closest metro station.

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Dates

January 2026

16

February 2026

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Our top choices for Otay Mesa West hotels

3 restaurants, breakfast, lunch, dinner served; Regional cuisine

Wyndham San Diego Bayside

19.2 km from Otay Mesa West

blasimar

₹17,291 total

includes taxes & fees

18 Jan - 19 Jan

The Bristol Hotel San Diego

18.5 km from Otay Mesa West

Zoe

₹39,257 total

includes taxes & fees

9 Feb - 10 Feb

Outdoor pool, open 7:00 AM to 10:00 PM, pool cabanas (surcharge)

San Diego Mission Bay Resort

Mission Bay, 26.8 km from Otay Mesa West

Dani

₹20,561 total

includes taxes & fees

2 Feb - 3 Feb

5 outdoor pools, a heated pool, pool umbrellas, pool loungers

Paradise Point Resort & Spa

Mission Bay, 27.9 km from Otay Mesa West

Andy

₹17,421 total

includes taxes & fees

19 Jan - 20 Jan

Loews Coronado Bay Resort

9.7 km from Otay Mesa West

Taryn

₹23,339 total

includes taxes & fees

8 Feb - 9 Feb

Westgate Hotel

18.5 km from Otay Mesa West

Victor

3 outdoor pools, pool cabanas (surcharge), pool umbrellas

Sycuan Casino Resort

31.2 km from Otay Mesa West

Flavia

Hard Rock Hotel San Diego

Gaslamp Quarter, 17.5 km from Otay Mesa West

Sergio

₹22,341 total

includes taxes & fees

19 Jan - 20 Jan

2 outdoor pools, a heated pool, pool loungers

The Dana on Mission Bay

Mission Bay, 27.1 km from Otay Mesa West

Megan

₹18,578 total

includes taxes & fees

18 Jan - 19 Jan

Standard Room, 1 King Bed, Non Smoking, Bay View | Premium bedding, pillow-top beds, in-room safe, desk

The DEXTRO Little Italy, BW Premier Collection

19.1 km from Otay Mesa West

Zoraima

₹11,558 total

includes taxes & fees

22 Jan - 23 Jan

Manchester Grand Hyatt San Diego

Marina District, 18.2 km from Otay Mesa West

Michelle

₹25,754 total

includes taxes & fees

22 Jan - 23 Jan

Humphreys Half Moon Inn

22.3 km from Otay Mesa West

Ryan

₹17,790 total

includes taxes & fees

2 Feb - 3 Feb

GreenTree Inn San Diego Mission Bay

Pacific Beach, 29.3 km from Otay Mesa West

Curtis

₹7,583 total

includes taxes & fees

25 Jan - 26 Jan

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

Gaslamp Quarter, 17.6 km from Otay Mesa West

Maryann

₹16,667 total

includes taxes & fees

18 Jan - 19 Jan

Hampton Inn San Diego/Mission Valley

23.5 km from Otay Mesa West

bill

₹9,996 total

includes taxes & fees

25 Jan - 26 Jan

Embassy Suites by Hilton San Diego Bay Downtown

Marina District, 18.4 km from Otay Mesa West

Kathy

₹23,021 total

includes taxes & fees

30 Jan - 31 Jan

The Sofia Hotel

18.5 km from Otay Mesa West

Stephanie

Best Western Seven Seas

22.9 km from Otay Mesa West

Thuan

₹7,286 total

includes taxes & fees

25 Jan - 26 Jan

Fairfield Inn & Suites by Marriott San Diego Pacific Beach

Pacific Beach, 29 km from Otay Mesa West

Cynthia

₹9,445 total

includes taxes & fees

25 Jan - 26 Jan

Margaritaville Hotel San Diego Gaslamp Quarter

Gaslamp Quarter, 17.6 km from Otay Mesa West

Ginger

₹22,263 total

includes taxes & fees

30 Jan - 31 Jan

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Where to stay in Otay Mesa West

Find the best Otay Mesa West areas for the activities you enjoy most. Learn more about Otay Mesa West

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

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Gaslamp Quarter

The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.

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Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

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Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

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Ocean Beach

With a secluded sunbathing beach, swimming-only beach, special surf beach, volleyball beach and dog beach, San Diego’s “OB” sure takes beaches seriously.

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