Search Hotels in Otay Mesa West, San Diego

Start date: Check-in selected.
To Date
End date: Check-out

    Change your mind

    Book hotels with free cancellation

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
16 Oct - 17 Oct
Tomorrow
17 Oct - 18 Oct
This weekend
17 Oct - 19 Oct
Next weekend
24 Oct - 26 Oct

Filter by

Guest rating
Guest rating
Star rating

Top Trending Hotels Near Otay Mesa West, San Diego

Rooftop terrace
Palihotel San Diego Gaslamp Quarter
Palihotel San Diego Gaslamp Quarter
4.0 star property
8.8 out of 10, Excellent, (1919)
"Staff was great location was great"
The price is ₹11,008
₹12,764 total
includes taxes & fees
20 Oct - 21 Oct
Palihotel San Diego Gaslamp Quarter
Lobby
El Cordova Hotel on Coronado Island
El Cordova Hotel on Coronado Island
3.5 star property
8.8 out of 10, Excellent, (1004)
"Cute and unique hotel！"
El Cordova Hotel on Coronado Island
Serves dinner and happy hour
The Horton Grand, Downtown/Gaslamp Quarter
The Horton Grand, Downtown/Gaslamp Quarter
3.5 star property
9.0 out of 10, Wonderful, (2608)
"Great location and friendly staff"
The Horton Grand, Downtown/Gaslamp Quarter
Outdoor pool
Ramada Suites by Wyndham San Diego/Hotel Circle Area
Ramada Suites by Wyndham San Diego/Hotel Circle Area
2.5 star property
6.2 out of 10, (1009)
"Clean room, friendly staff"
The price is ₹6,288
₹7,228 total
includes taxes & fees
21 Oct - 22 Oct
Ramada Suites by Wyndham San Diego/Hotel Circle Area
Exterior
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
3.0 star property
9.0 out of 10, Wonderful, (1172)
"Clean room ,friendly staff, great location "
The price is ₹11,390
₹13,206 total
includes taxes & fees
20 Oct - 21 Oct
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
Terrace/patio
Wyndham San Diego Bayside
Wyndham San Diego Bayside
4.0 star property
8.4 out of 10, Very good, (5979)
"Enjoyed our stay very much."
The price is ₹13,363
₹18,040 total
includes taxes & fees
23 Oct - 24 Oct
Wyndham San Diego Bayside
Suite, 2 Queen Beds, Non Smoking, Refrigerator (with Sofabed) | Premium bedding, in-room safe, desk, laptop workspace
Best Western Plus Marina Gateway Hotel
Best Western Plus Marina Gateway Hotel
3.5 star property
9.2 out of 10, Wonderful, (3350)
"Nice place to stay !"
The price is ₹11,018
₹12,141 total
includes taxes & fees
2 Nov - 3 Nov
Best Western Plus Marina Gateway Hotel
Outdoor pool, pool loungers
Best Western Plus Suites Hotel Coronado Island
Best Western Plus Suites Hotel Coronado Island
2.5 star property
8.8 out of 10, Excellent, (1012)
"Great staff and breakfast "
The price is ₹14,545
₹16,000 total
includes taxes & fees
26 Oct - 27 Oct
Best Western Plus Suites Hotel Coronado Island
Standard Room, 1 King Bed, Smoking | Desk, laptop workspace, iron/ironing board, free WiFi
Days Inn by Wyndham San Diego-East/El Cajon
Days Inn by Wyndham San Diego-East/El Cajon
2.0 star property
7.6 out of 10, Good, (1003)
"Place was nice and comfy. Decent stay at a very genuine price. "
The price is ₹7,230
₹7,967 total
includes taxes & fees
16 Nov - 17 Nov
Days Inn by Wyndham San Diego-East/El Cajon
Lobby
Gaslamp Plaza Suites
Gaslamp Plaza Suites
3.5 star property
8.8 out of 10, Excellent, (1018)
"Had a great stay "
The price is ₹9,511
₹10,819 total
includes taxes & fees
29 Oct - 30 Oct
Gaslamp Plaza Suites
Lobby
Super 8 by Wyndham El Cajon/San Diego
Super 8 by Wyndham El Cajon/San Diego
2.0 star property
7.8 out of 10, Good, (1006)
"Over all it was good."
The price is ₹6,345
₹6,992 total
includes taxes & fees
16 Nov - 17 Nov
Super 8 by Wyndham El Cajon/San Diego
Outdoor pool
Hard Rock Hotel San Diego
Hard Rock Hotel San Diego
4.0 star property
9.0 out of 10, Wonderful, (3026)
"Great stay"
The price is ₹18,151
₹25,087 total
includes taxes & fees
20 Oct - 21 Oct
Hard Rock Hotel San Diego
Lobby
Best Western Plus La Mesa San Diego
Best Western Plus La Mesa San Diego
2.5 star property
8.2 out of 10, Very good, (1010)
"Excelent place to stay."
The price is ₹9,441
₹10,385 total
includes taxes & fees
2 Nov - 3 Nov
Best Western Plus La Mesa San Diego
Front of property
The Sofia Hotel
The Sofia Hotel
3.5 star property
8.4 out of 10, Very good, (1621)
"I loved the stay here, highly recommended "
The Sofia Hotel
Exterior
Loews Coronado Bay Resort
Loews Coronado Bay Resort
4.0 star property
8.8 out of 10, Excellent, (1049)
"Beautiful quiet hotel."
The price is ₹17,525
₹23,461 total
includes taxes & fees
26 Oct - 27 Oct
Loews Coronado Bay Resort
Property entrance
The Bristol Hotel San Diego
The Bristol Hotel San Diego
3.5 star property
8.4 out of 10, Very good, (1404)
"Very nice staff from check in, clean rooms, quiet and comfortable. "
The price is ₹27,407
₹31,777 total
includes taxes & fees
18 Oct - 19 Oct
The Bristol Hotel San Diego
Lobby
Days Inn by Wyndham Chula Vista/San Diego
Days Inn by Wyndham Chula Vista/San Diego
2.0 star property
6.2 out of 10, (1027)
"Great visit. Staff was very helpful"
The price is ₹6,662
₹7,342 total
includes taxes & fees
19 Oct - 20 Oct
Days Inn by Wyndham Chula Vista/San Diego
Exterior
AC Hotel by Marriott San Diego Downtown Gaslamp Quarter
AC Hotel by Marriott San Diego Downtown Gaslamp Quarter
4.0 star property
8.8 out of 10, Excellent, (935)
"Would definitely stay again!"
The price is ₹13,386
₹15,521 total
includes taxes & fees
21 Oct - 22 Oct
AC Hotel by Marriott San Diego Downtown Gaslamp Quarter
Premium bedding, pillow-top beds, desk, laptop workspace
Staypineapple, Hotel Z, Gaslamp San Diego
Staypineapple, Hotel Z, Gaslamp San Diego
3.0 star property
9.4 out of 10, Exceptional, (1002)
"Perfect location. "
The price is ₹12,012
₹16,473 total
includes taxes & fees
2 Nov - 3 Nov
Staypineapple, Hotel Z, Gaslamp San Diego
Exterior
La Pensione Hotel
La Pensione Hotel
3.0 star property
8.6 out of 10, Excellent, (1888)
"Very happy with our stay "
La Pensione Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Where to stay in Otay Mesa West

Find the best Otay Mesa West areas for the activities you enjoy most. Learn more about Otay Mesa West
Learn more about Otay Mesa West

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Gaslamp Quarter featuring a bar, night scenes and street scenes

Gaslamp Quarter

The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.

Pacific Beach Park showing a beach

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Belmont Park featuring a park and rides

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Ocean Beach

With a secluded sunbathing beach, swimming-only beach, special surf beach, volleyball beach and dog beach, San Diego’s “OB” sure takes beaches seriously.

Top Otay Mesa West Hotel Reviews

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

10/10 Excellent
"Great"
Christopher 1-night trip
Posted 19 hours ago
Hard Rock Hotel San Diego

Explore a world of travel with Expedia

Frequently asked questions

What is Otay Mesa West like?
Otay Mesa West is a neighbourhood that travellers like for its cathedral.
If I need to cancel my hotel reservation in Otay Mesa West, will I receive a refund?
Yes! The majority of room reservations are refundable if you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of your booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to review top deals in Otay Mesa West.
What is there to do around this San Diego neighbourhood?
A few places to visit in the area around Otay Mesa West include San Ysidro Border Crossing, Las Americas Premium Outlets and Sesame Place San Diego. While you're out sightseeing in San Diego, make sure that you visit other sights such as Tijuana Customs - Garita El Chaparral or North Island Credit Union Amphitheatre.
How can I get around Otay Mesa West and the greater San Diego area?
Ready to get out and explore the city? Iris Avenue Trolley Station is the closest metro station.