𝗧𝗢𝗣 𝟭𝟬 𝗛𝗼𝘁𝗲𝗹𝘀 𝗶𝗻 Southeast Minnesota (2026)

A mural of Red Wing with a steamship, houses, and a bridge.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Go beyond your typical stay in Southeast Minnesota

Pet friendly

Apartment

Spa

Pool

Hot tub

Condo

Family friendly

Cottage

Waterpark

Check prices for these dates

Tonight

Tomorrow

Next weekend

In two weeks

Our top choices for Southeast Minnesota hotels

A modern dining area with high tables, chairs, and pendant lighting.

A reception desk with a large digital screen displaying a cityscape and the word "happy."

A multi-story hotel with a modern design, featuring a prominent entrance with a covered area and a parking lot in front.

A hotel room with two beds, a desk with a computer, a chair, and a window with a view.

1. Hampton Inn & Suites Rochester-North

Rochester

Mark

₹9,732

₹11,204 total

includes taxes & fees

6 Nov - 7 Nov

An outdoor seating area with a fire feature, blue cushioned chairs, and a modern building with large windows in the background.

A modern indoor pool area with lounge chairs and a pool.

A modern Hyatt House hotel with a prominent 'Hyatt House' sign, multiple floors, and a parking garage.

A modern bar area with seating and a counter.

2. Hyatt House Rochester/Mayo Clinic Area

Downtown Rochester

Arlan

₹12,058

₹13,881 total

includes taxes & fees

13 Nov - 14 Nov

A coffee shop interior with a wooden counter, menu boards, and seating area.

A hotel exterior with a 'Townplace Suites' sign, outdoor seating area, and 'OPEN' signage.

A hotel room with a bed, bedside table, and a window with curtains.

An outdoor seating area with tables and chairs, a neon sign, and flower arrangements.

3. TownePlace Suites by Marriott Rochester Mayo Clinic Area

Kutzky Park

Cory

₹13,007

₹14,974 total

includes taxes & fees

6 Nov - 7 Nov

A Comfort Inn hotel with a stone facade, a covered entrance, and a parking area.

A spacious lobby with a central seating area, a reception desk, and a fireplace.

A spacious living room with a stone fireplace, blue sofas, and a flat-screen TV.

A modern dining area with wooden tables and chairs, a kitchen with granite countertops, and a view of the outdoors through large windows.

4. Comfort Inn & Suites West - Medical Center

Rochester

Tammy

₹8,192

₹9,431 total

includes taxes & fees

15 Nov - 16 Nov

A modern indoor patio with a fire feature, seating, and large windows.

A modern hotel lobby with a large glass wall, a green wall mural, and a seating area with sofas and chairs.

A modern living room with a fireplace, large windows, and a flat-screen TV mounted on the wall.

A reception area with a curved reception desk, wooden shelving, and a green moss wall with the text "I ♥ EVEN".

5. EVEN Hotel Rochester - Mayo Clinic Area by IHG

Kutzky Park

James

₹10,444

₹13,306 total

includes taxes & fees

6 Nov - 7 Nov

An outdoor patio area with a concrete floor, wooden fence, and string lights.

A Fairfield Inn & Suites hotel with a modern design, featuring a prominent entrance and a parking area.

A breakfast bar with a wooden counter, a coffee machine, and a refrigerator.

A modern living room with a stone fireplace, a blue armchair, a round coffee table, and a large window offering a view of the outdoors.

6. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Kutzky Park

Brien

₹11,023

₹12,690 total

includes taxes & fees

6 Nov - 7 Nov

A modern hotel lobby with multiple seating areas, including a central dining table with chairs, a bar area, and a seating section with cushioned chairs.

A modern conference room with a long table, multiple chairs, and a wooden partition.

A modern hotel room with a large bed, two bedside tables, and built-in lighting.

A modern lounge area with a curved sofa, a round table, and a seating area with chairs.

7. SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

Kutzky Park

Jackie

₹10,596

₹12,198 total

includes taxes & fees

1 Nov - 2 Nov

An outdoor seating area with wooden pillars, colorful striped cushions, and potted plants.

An indoor swimming pool with wooden ceiling beams, yellow chairs, and tables along the sides.

A modern hotel room with a bed, desk, and kitchenette.

A modern restaurant with a counter, seating area, and a TV screen.

8. Home2 Suites by Hilton Rochester Mayo Clinic Area

Rochester

howard

₹10,410

₹11,985 total

includes taxes & fees

7 Nov - 8 Nov

A spacious lobby with a reception desk, sofas, and a coffee table.

A lobby with a brown sofa, yellow armchairs, a coffee table, and a clock on the wall.

A Sleep Inn hotel with a covered entrance, stone pillars, and a clear blue sky.

A hotel room with a large bed, a sofa, a TV, and a desk.

9. Sleep Inn & Suites West-Near Medical Center

Rochester

Jacqueline

₹7,348

₹8,459 total

includes taxes & fees

22 Nov - 23 Nov

A Comfort Inn & Suites hotel with a modern design, featuring a prominent signage and a parking lot.

A modern living room with a sofa, two armchairs, a coffee table, and a large window offering a view of the outdoors.

A modern dining area with tables and chairs, a kitchen area with appliances, and a large window providing natural light.

A reception desk with a wooden finish, a large illuminated 'C' sign, and a modern light fixture on the ceiling.

10. Comfort Inn & Suites Rochester South Mayo Clinic

Rochester

Terri

₹7,126

₹8,204 total

includes taxes & fees

7 Nov - 8 Nov

A self-service breakfast station with a waffle maker, coffee machines, and a variety of condiments.

A reception area with a wooden reception desk, a red doormat, and framed awards on the wall.

A compact laundry area with a washing machine, dryer, and a water fountain.

A hotel lobby with leather sofas, a stone fireplace, and a patterned carpet.

11. Econo Lodge Mayo Clinic Area

Rochester

Ashley

₹6,275

₹7,224 total

includes taxes & fees

15 Nov - 16 Nov

A restaurant with wooden tables and bar stools, a bar area with a counter, and multiple televisions mounted on the walls.

A modern kitchen with wooden cabinets, a microwave, an oven, and a dishwasher.

A hotel room with two beds, a desk, a chair, and a mirror.

An indoor swimming pool with a slide, seating area, and a large frog statue.

12. AmericInn by Wyndham Rochester Near Mayo Clinic

Rochester

blake

₹7,162

₹8,246 total

includes taxes & fees

8 Nov - 9 Nov

A hotel reception desk with a wooden counter, a computer, and a vase with flowers.

A living room with stone walls, a fireplace, leather furniture, and a ceiling fan.

A hotel room with a large bed, a separate bathroom with a bathtub, and a skylight ceiling.

A hotel room with a large bed, a view through a sliding glass door to an outdoor area, a nightstand with a lamp, and a wooden headboard.

13. Baymont by Wyndham Kasson Rochester Area

Kasson

Dana

₹6,214

₹6,672 total

includes taxes & fees

1 Nov - 2 Nov

A modern living room with a flat-screen TV, a fireplace, a sofa, a coffee table, and a view of a cityscape through large windows.

A hotel swimming pool with lounge chairs, a changing room, and a view of the cityscape.

A spacious lobby with modern furniture, a staircase, and large windows.

A spacious lobby with a curved staircase, comfortable seating areas, and large windows offering views of the outdoors.

14. Hilton Rochester Mayo Clinic Area

Downtown Rochester

Jennifer

₹16,867

₹19,418 total

includes taxes & fees

7 Nov - 8 Nov

A swimming pool with a glass ceiling, a neon sign for the KAFFLER HOTEL, and a view of the city skyline at dusk.

A hotel entrance with a modern design, large windows, and a sign indicating it's a Grand Hotel.

A banquet hall with round tables, chairs, chandeliers, and a fireplace.

A hotel room with a large bed, a desk, a chair, a microwave, and a framed picture on the wall.

15. Kahler Grand Hotel

Downtown Rochester

Christina

₹13,435

₹15,467 total

includes taxes & fees

7 Nov - 8 Nov

A reception area with a wooden reception desk, a "Welcome to the Bread & Butter State" sign, and a "Please Center" sign.

A hotel room with a bed, a desk, a chair, a TV, and a bathroom visible through an open door.

A coffee station with four coffee dispensers, a stack of disposable cups, and a tray with various coffee-related items.

A pool area with a table and chairs, a lifeguard chair, and a pool lift.

16. Hampton Inn Rochester-South

Rochester

dennis

₹9,281

₹10,684 total

includes taxes & fees

1 Nov - 2 Nov

A spacious outdoor dining area with multiple tables and chairs, large windows, and a wooden ceiling structure.

An outdoor dining area with wooden beams, tables, and chairs.

A bar area with a central island, bar stools, and hanging pendant lights.

A modern hotel building with a prominent sign for 'Hotel Indigo' and a 'Crave Drink' establishment.

17. Hotel Indigo Rochester – Mayo Clinic Area by IHG

Downtown Rochester

Naomi

₹9,779

₹11,258 total

includes taxes & fees

14 Nov - 15 Nov

A modern hotel lobby with a reception desk, seating area, and a dining space.

A Holiday Inn Express building with a stone facade and illuminated signage.

A modern hotel room with a wooden desk, orange chair, dark sofa, and a small table.

A modern breakfast area with a counter displaying various food items, a water dispenser, and a sign indicating a bakery section.

18. Holiday Inn Express Rochester South - Mayo Area by IHG

Rochester

Rick

₹8,545

₹9,838 total

includes taxes & fees

13 Nov - 14 Nov

An outdoor patio with a brick floor, stone fireplace, and wooden pergola.

An indoor swimming pool with clear pool rules posted on the wall, a lifeguard chair, and a pool lift sign.

A conference room with tables set for a meeting, a projector screen, and a view of the outside.

A gym with exercise equipment, a clock, and a window with blinds.

19. Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

Kutzky Park

Lin

₹10,410

₹11,985 total

includes taxes & fees

25 Nov - 26 Nov

A Staybridge Suites hotel with a stone facade, a covered entrance, and multiple windows.

An indoor swimming pool with clear water, surrounded by lounge chairs and a sunbed.

An outdoor patio area with stone walls, outdoor seating, and landscaped gardens.

A modern kitchen with dark wood cabinets, stainless steel appliances, and a central island with seating.

20. Staybridge Suites Rochester - Commerce Dr NW by IHG

Rochester

MATTHEW

₹11,013

₹12,679 total

includes taxes & fees

7 Nov - 8 Nov

View all properties

Holiday Rentals in Southeast Minnesota

Aparthotel

A spacious living area with a modern staircase, leather sofas, and contemporary lighting.

An outdoor seating area with blue sofas and wicker chairs, a wooden table, and green ottomans on a tiled patio.

A modern pool table in a spacious, well-lit room with large windows and a bar area.

A rooftop pool area with lounge chairs and umbrellas, surrounded by a modern building with a brick facade.

The Berkman

Folwell

"Excellent service and wonderful room!"

Apartment

A bedroom with a large bed, a TV on a dresser, and a view of the city through large windows.

A multi-story building with the sign 'Broadway Plaza' indicating a commercial or hotel property.

An indoor swimming pool with a clock on the wall, lounge chairs, and a lifeguard warning sign.

A modern kitchen with wooden cabinets, a granite countertop, and a stainless steel stove.

Broadway Plaza, Trademark Collection by Wyndham

Downtown Rochester

"Clean room and great location"

Apartment

A wooden interior with a kitchen, bar area, and a staircase.

A wooden cabin interior with a bed, a ceiling light, and a window.

A modern kitchen with stainless steel appliances, wooden cabinets, and a stone tile floor.

A two-story building with a storefront featuring a sign for coffee, ice cream, and craft drinks. There are steps leading to the entrance, a bench outside, and potted plants.

Lake Pepin Escape: Loft Cottage & Fireplace

Pepin

"Great location and very well furnished with new appliances."

Apartment

A modern kitchen with a central island, bar stools, and a large window.

A spacious living room with a large sofa set, a wooden coffee table, and a large window.

A deck with two wooden chairs and a fire pit.

A spacious living area with a large sofa, a coffee table, and a dining table with chairs. There is a ceiling fan and a floor lamp.

1 Block to Lake City Marina: Condo w/ Rooftop Deck

Lake City

"Wonderful property, spacious, well-appointed and comfortable. Would definitely rent again."

Apartment

A bedroom with a bed, a chair, a table, a fireplace, and a ceiling fan.

A kitchen with wooden cabinets, stainless steel appliances, and a dining table with chairs.

A single-story house with a front porch, a small staircase leading to a deck, and a stone retaining wall.

A wooden deck with Adirondack chairs lined up against a building with a flag.

Pet-friendly Wabasha Studio: Boat, Ski & Explore!

Wabasha

"Great property! Very convenient location as well."

Cottage

A modern interior with a stone fireplace, wooden walls, a leather sofa, and a dining area.

A log cabin interior with a wooden ceiling, a red sofa, a brown leather couch, and a person seated on a chair.

A cozy interior with a wooden ceiling, a fireplace, a red sofa, a leather couch, and a foosball table.

A kitchen with wooden cabinets, a stove, a sink, and a window with a view of trees.

Pet-friendly Cabin Retreat: Walk to Lake Pepin!

Pepin

"What a fun place! Plenty of room. We played foosball had a fire outside. We enjoyed the fireplace too. We hadn’t anticipated no TV though. You might want to add that to your description. The water is definitely smelly, so we truly appreciated the 40 bottles of water you provided. Definitely a great place for a girl’s weekend or family reunion!"

See all holiday rentals

Hotels recommended for families in Southeast Minnesota

Hampton Inn & Suites Rochester-North

Rochester

₹9,732

₹11,204 total

includes taxes & fees

6 Nov - 7 Nov

EVEN Hotel Rochester - Mayo Clinic Area by IHG

Kutzky Park

₹10,444

₹13,306 total

includes taxes & fees

6 Nov - 7 Nov

Hyatt House Rochester/Mayo Clinic Area

Downtown Rochester

₹12,058

₹13,881 total

includes taxes & fees

13 Nov - 14 Nov

Comfort Inn & Suites West - Medical Center

Rochester

₹8,192

₹9,431 total

includes taxes & fees

15 Nov - 16 Nov

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Kutzky Park

₹11,023

₹12,690 total

includes taxes & fees

6 Nov - 7 Nov

TownePlace Suites by Marriott Rochester Mayo Clinic Area

Kutzky Park

₹13,007

₹14,974 total

includes taxes & fees

6 Nov - 7 Nov

Home2 Suites by Hilton Rochester Mayo Clinic Area

Rochester

₹10,410

₹11,985 total

includes taxes & fees

7 Nov - 8 Nov

Comfort Inn & Suites Rochester South Mayo Clinic

Rochester

₹7,126

₹8,204 total

includes taxes & fees

7 Nov - 8 Nov

Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Southeast Minnesota attractions

Villa Bellezza

8.4/10 (31 reviews)

You can enjoy a tasting or tour at Villa Bellezza during your travels to Pepin. While you're in the area, stroll along the lakeside.

See properties

Mayo Civic Center

9.2/10 (818 reviews)

Catch an event at Mayo Civic Center during your trip to Rochester. Attend a sporting event or simply visit the area's shops.

See properties

Apache Mall

8.6/10 (1,101 reviews)

During your visit to Rochester, you can find the perfect gifts to bring home at Apache Mall. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

See properties

Rochester Recreation Center

8.0/10 (205 reviews)

Catch an event at Rochester Recreation Center during your trip to Rochester. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

See properties

National Volleyball Center

7.8/10 (151 reviews)

Catch an event at National Volleyball Center during your trip to Rochester. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

See properties

Welch Village Ski Area

8.6/10 (16 reviews)

Hit the slopes in Welch with a visit to Welch Village Ski Area. Stroll along the area's riverfront or simply enjoy its cafes.

See properties

Shattuck-St. Mary's School

9.6/10 (69 reviews)

Explore the campus of Shattuck-St. Mary's School during your trip to Faribault. Visit the shops in this family-friendly area or simply enjoy its cafes.

See properties

Mayowood Mansion

9.4/10 (29 reviews)

You can spend time studying the exhibits at Mayowood Mansion in Rochester. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

See properties

Learn more about Southeast Minnesota

Discover the family-friendly area of Southeast Minnesota—sports teams, a scenic riverfront and sights from Mayowood Mansion to Apache Mall.

See all hotels in Southeast Minnesota

A lake surrounded by dense forest and a distant hill with a fort.

Top Southeast Minnesota Hotel Reviews

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

8/10 Good

"Comfortable place. Nice patio that allows pets."

Treasure Island Resort & Casino

8/10 Good

"Clean room but no microwave."

Cobblestone Hotel & Suites - Austin

8/10 Good

"We chose this hotel because it had a bar. I wanted to take a glass of wine back to my room. What a disappointment! There was one bottle of very bad of red and a warm Chardonnay. Okay I’ll have a gin and tonic. Nope. No tonic. The receptionist doubled a bartender. She did her best but didn’t have much to work with"

AmericInn by Wyndham Rochester Near Mayo Clinic

8/10 Good

"The room had some noise like water going thru some pipes during the early morning hours. Could be something due to the swimming pool. No sleep after that started."

Hotel Indigo Rochester – Mayo Clinic Area by IHG

10/10 Excellent

"Staff was extremely helpful and knowledgeable. Restaurant was clean and food was great. Very close to everything and parking was easy and inexpensive."

Hyatt House Rochester/Mayo Clinic Area

10/10 Excellent

"B"

Brentwood Inn & Suites

8/10 Good

"While the property is old, I found it very clean. Location is excellent. Bed was not great. Staff was incredibly accommodating."

More cheap stays in Southeast Minnesota

Super 8 by Wyndham Winona MN

1025 Sugar Loaf Rd Winona MN

₹4,614

₹5,242 total

15 Nov - 16 Nov

includes taxes & fees

Quality Inn near Medical Center

5708 Bandel Road NW Rochester MN

₹5,972

₹6,875 total

15 Nov - 16 Nov

includes taxes & fees

Med City Inn & Suites - Mayo Clinic Area

435 16th Ave Nw Rochester MN

₹6,747

₹7,767 total

25 Nov - 26 Nov

includes taxes & fees

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

1517 16th St Sw Rochester MN

₹9,417

₹10,842 total

1 Nov - 2 Nov

includes taxes & fees

Cobblestone Hotel & Suites - Austin

1000 16th Avenue NW Austin MN

₹10,102

₹11,200 total

1 Nov - 2 Nov

includes taxes & fees

8.8/10 Excellent! (836 reviews)

Brentwood Inn & Suites

123 Fourth Ave. NW Rochester MN

₹11,393

₹13,116 total

29 Oct - 30 Oct

includes taxes & fees

8.8/10 Excellent! (1,005 reviews)

Hotels in Southeast Minnesota with star rating

Explore a world of travel with Expedia

Book Hotels in Southeast Minnesota on Expedia.com

Southeast Minnesota Hotels from ₹5,242

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Southeast Minnesota

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Southeast Minnesota hotels

1. Hampton Inn & Suites Rochester-North

2. Hyatt House Rochester/Mayo Clinic Area

3. TownePlace Suites by Marriott Rochester Mayo Clinic Area

4. Comfort Inn & Suites West - Medical Center

5. EVEN Hotel Rochester - Mayo Clinic Area by IHG

6. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

7. SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

8. Home2 Suites by Hilton Rochester Mayo Clinic Area

9. Sleep Inn & Suites West-Near Medical Center

10. Comfort Inn & Suites Rochester South Mayo Clinic

11. Econo Lodge Mayo Clinic Area

12. AmericInn by Wyndham Rochester Near Mayo Clinic

13. Baymont by Wyndham Kasson Rochester Area

14. Hilton Rochester Mayo Clinic Area

15. Kahler Grand Hotel

16. Hampton Inn Rochester-South

17. Hotel Indigo Rochester – Mayo Clinic Area by IHG

18. Holiday Inn Express Rochester South - Mayo Area by IHG

19. Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

20. Staybridge Suites Rochester - Commerce Dr NW by IHG

Holiday Rentals in Southeast Minnesota

The Berkman

Broadway Plaza, Trademark Collection by Wyndham

Lake Pepin Escape: Loft Cottage & Fireplace

1 Block to Lake City Marina: Condo w/ Rooftop Deck

Pet-friendly Wabasha Studio: Boat, Ski & Explore!

Pet-friendly Cabin Retreat: Walk to Lake Pepin!

Hotels recommended for families in Southeast Minnesota

Hampton Inn & Suites Rochester-North

EVEN Hotel Rochester - Mayo Clinic Area by IHG

Hyatt House Rochester/Mayo Clinic Area

Comfort Inn & Suites West - Medical Center

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

TownePlace Suites by Marriott Rochester Mayo Clinic Area

Home2 Suites by Hilton Rochester Mayo Clinic Area

Comfort Inn & Suites Rochester South Mayo Clinic

Stay near popular Southeast Minnesota attractions

Villa Bellezza

Mayo Civic Center

Apache Mall

Rochester Recreation Center

National Volleyball Center

Welch Village Ski Area

Shattuck-St. Mary's School

Mayowood Mansion

Learn more about Southeast Minnesota

Top Southeast Minnesota Hotel Reviews

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Treasure Island Resort & Casino

Cobblestone Hotel & Suites - Austin

AmericInn by Wyndham Rochester Near Mayo Clinic

Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hyatt House Rochester/Mayo Clinic Area

Brentwood Inn & Suites

More cheap stays in Southeast Minnesota

Super 8 by Wyndham Winona MN

Quality Inn near Medical Center

Med City Inn & Suites - Mayo Clinic Area

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Cobblestone Hotel & Suites - Austin

Brentwood Inn & Suites

Hotels in Southeast Minnesota with star rating

Explore a world of travel with Expedia

Go further with the Expedia app