An aerial view of a town with industrial buildings, roads, and green areas.

St. Charles Hotels from ₹6,584

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Check prices for these dates

This weekend
24 Jul - 26 Jul
Next weekend
31 Jul - 2 Aug

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Our top choices for St. Charles hotels

Reception

1. Spark by Hilton Rochester South

Spark by Hilton Rochester South
3.0 star property
Rochester
9.2 out of 10, Wonderful, (533 reviews)
"Clean room, nice staff, good breakfast"
United States
Lijing
The price is ₹7,048
₹8,114 total
includes taxes & fees
16 Aug - 17 Aug
Spark by Hilton Rochester South
Studio Suite, 1 King Bed, Non Smoking | Desk, blackout curtains, iron/ironing board, free cots/infant beds

2. AmericInn by Wyndham Winona

AmericInn by Wyndham Winona
3.0 star property
Winona
9.2 out of 10, Wonderful, (968 reviews)
"Very clean, wonderful pool area and very good breakfast."
United States
Jacob
The price is ₹11,657
₹13,012 total
includes taxes & fees
9 Aug - 10 Aug
AmericInn by Wyndham Winona
Lobby

3. Comfort Inn & Suites Rochester South Mayo Clinic

Comfort Inn & Suites Rochester South Mayo Clinic
2.0 star property
Rochester
8.8 out of 10, Excellent, (1,006 reviews)
"Really like this hotel!"
United States
Stephanie
The price is ₹7,549
₹8,691 total
includes taxes & fees
9 Aug - 10 Aug
Comfort Inn & Suites Rochester South Mayo Clinic
Reception

4. Hampton Inn Rochester-South

Hampton Inn Rochester-South
2.5 star property
Rochester
9.0 out of 10, Wonderful, (1,003 reviews)
"Great hotel, excellent breakfast, friendly staff"
United States
Richard
The price is ₹8,014
₹9,226 total
includes taxes & fees
20 Aug - 21 Aug
Hampton Inn Rochester-South
Front of property

5. La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
3.0 star property
Rochester
7.4 out of 10, Good, (1,076 reviews)
"The staff was very helpful!!!"
United States
Jolene
The price is ₹7,306
₹8,411 total
includes taxes & fees
23 Aug - 24 Aug
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Lobby

6. Super 8 by Wyndham Rochester Mayo Clinic Area

Super 8 by Wyndham Rochester Mayo Clinic Area
2.0 star property
Rochester
7.8 out of 10, Good, (1,004 reviews)
"Will definitely be staying there again."
United States
Amber
The price is ₹5,007
₹5,765 total
includes taxes & fees
1 Aug - 2 Aug
Super 8 by Wyndham Rochester Mayo Clinic Area
In-room safe, desk, blackout curtains, iron/ironing board

7. Days Inn by Wyndham Winona

Days Inn by Wyndham Winona
2.0 star property
Winona
7.8 out of 10, Good, (1,000 reviews)
"My room was very nice very clean and it was an exceptional stay"
United States
Twila
The price is ₹6,567
₹7,330 total
includes taxes & fees
10 Aug - 11 Aug
Days Inn by Wyndham Winona
Terrace/patio

8. Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area
3.0 star property
Downtown Rochester
9.0 out of 10, Wonderful, (1,002 reviews)
"Great room and good breakfast!"
United States
Bridgett
The price is ₹15,355
₹17,677 total
includes taxes & fees
26 Jul - 27 Jul
Hyatt House Rochester/Mayo Clinic Area
Exterior

9. Holiday Inn Express Rochester South - Mayo Area by IHG

Holiday Inn Express Rochester South - Mayo Area by IHG
2.5 star property
Rochester
8.8 out of 10, Excellent, (1,000 reviews)
"Breakfast was good and had good options. Great location for movies, restaurants, and shopping!"
United States
Laura
The price is ₹8,743
₹10,065 total
includes taxes & fees
24 Aug - 25 Aug
Holiday Inn Express Rochester South - Mayo Area by IHG
Lobby lounge

10. Fairfield Inn & Suites by Marriott Winona

Fairfield Inn & Suites by Marriott Winona
3.0 star property
Winona
9.4 out of 10, Exceptional, (391 reviews)
"Clean sheets, hot shower, good breakfast with tons of options."
United States
Micaiah
The price is ₹14,389
₹16,062 total
includes taxes & fees
26 Jul - 27 Jul
Fairfield Inn & Suites by Marriott Winona
Indoor pool, open 9:00 AM to 10:00 PM, pool umbrellas, pool loungers

11. Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
2.5 star property
Rochester
8.2 out of 10, Very good, (1,000 reviews)
"Clean, breakfast, nice pool area and complimentary shuttle to Mayo"
United States
Barbara
The price is ₹9,083
₹10,456 total
includes taxes & fees
9 Aug - 10 Aug
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Serves lunch, dinner and happy hour

12. AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic
3.0 star property
Rochester
8.0 out of 10, Very good, (1,394 reviews)
"Our room was very nice and we liked that there was a restaurant attached that was very good. Would stay again!"
United States
Julie
The price is ₹7,524
₹8,662 total
includes taxes & fees
23 Aug - 24 Aug
AmericInn by Wyndham Rochester Near Mayo Clinic
In-room safe, desk, iron/ironing board, free cots/infant beds

13. Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
2.0 star property
Rochester
8.0 out of 10, Very good, (1,002 reviews)
"Clean place. Nice staff"
Canada
Leah
The price is ₹6,895
₹7,938 total
includes taxes & fees
5 Aug - 6 Aug
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
Free daily full breakfast

14. Econo Lodge Mayo Clinic Area

Econo Lodge Mayo Clinic Area
2.0 star property
Rochester
9.0 out of 10, Wonderful, (1,005 reviews)
"We had a nice stay"
United States
Daniel
The price is ₹6,855
₹7,891 total
includes taxes & fees
23 Aug - 24 Aug
Econo Lodge Mayo Clinic Area
Desk, laptop workspace, soundproofing, iron/ironing board

15. MainStay Suites Rochester South Mayo Clinic

MainStay Suites Rochester South Mayo Clinic
2.5 star property
Rochester
7.4 out of 10, Good, (125 reviews)
"This was a nice place to stay especially for the price!! I would recommend."
United States
Brian
The price is ₹5,963
₹6,865 total
includes taxes & fees
25 Jul - 26 Jul
MainStay Suites Rochester South Mayo Clinic
Room, 2 Queen Beds, Non Smoking (Pet-Friendly) | Desk, laptop workspace, blackout curtains, free WiFi

16. Super 8 by Wyndham Winona MN

Super 8 by Wyndham Winona MN
2.0 star property
Winona
7.8 out of 10, Good, (1,015 reviews)
"Great value for decent rooms and breakfast in the morning."
United States
Nicole
The price is ₹5,794
₹6,584 total
includes taxes & fees
26 Jul - 27 Jul
Super 8 by Wyndham Winona MN
Deluxe Double Room | Down duvets, pillow-top beds, blackout curtains, soundproofing

17. Country Trails Inn & Suites

Country Trails Inn & Suites
2.0 star property
Preston
9.4 out of 10, Exceptional, (131 reviews)
"Nicely run, clean, comfortable motel. I’d stay again."
United States
Robert
The price is ₹12,215
₹13,482 total
includes taxes & fees
27 Jul - 28 Jul
Country Trails Inn & Suites
Terrace/patio

18. Home2 Suites by Hilton Rochester Mayo Clinic Area

Home2 Suites by Hilton Rochester Mayo Clinic Area
3.0 star property
Rochester
9.6 out of 10, Exceptional, (1,001 reviews)
"Nice room great breakfast"
United States
Timothy
The price is ₹11,799
₹13,584 total
includes taxes & fees
8 Aug - 9 Aug
Home2 Suites by Hilton Rochester Mayo Clinic Area
Exterior

19. Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG

Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
2.5 star property
Kutzky Park
8.6 out of 10, Excellent, (815 reviews)
"I appreciated the location and the free Wi-Fi and parking."
United States
Dawn
The price is ₹9,754
₹11,229 total
includes taxes & fees
22 Aug - 23 Aug
Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
View from property

20. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
3.0 star property
Kutzky Park
9.6 out of 10, Exceptional, (725 reviews)
"Great location close to St. Marys. The hotel is nice, coffee is good, and overall a nice place to stay."
United States
Brian
The price is ₹12,081
₹13,908 total
includes taxes & fees
7 Aug - 8 Aug
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about St. Charles

St. Charles awaits: its natural setting and more!

See all hotels in St. Charles
An aerial view of a town with industrial buildings, roads, and green areas.

Top St. Charles Hotel Reviews

Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

10/10 Excellent
"My experience at the Hotel Indigo was fantastic. Sandy was absolutely amazing:! She went above and beyond to made an already stressful trip so comfortable and truly made us feel at home. Larry was also amazing, making sure that my daughter and I got to all her appointments on time, and back to the hotel safely. He also helped ensure in so many ways that our stay was as comfortable as possible. I highly recommend staying here!!"
Siobhan 4-night trip
Posted 7 hours ago
Hotel Indigo Rochester – Mayo Clinic Area by IHG

More cheap stays in St. Charles

Super 8 by Wyndham Winona MN

Super 8 by Wyndham Winona MN

1025 Sugar Loaf Rd Winona MN
The price is ₹5,794 per night from 26 Jul to 27 Jul
₹5,794
₹6,584 total
26 Jul - 27 Jul
includes taxes & fees

Frequently asked questions

Where is the best place to stay in St. Charles?
Kahler Grand Hotel, located 20.6 mi (33.1 km) from the heart of St. Charles, is a top choice for your stay, based on our traveller data. Two other options for your stay in the area are Kahler Inn and Suites - Mayo Clinic Area and Best Western Rochester Hotel Mayo Clinic Area/St. Mary's. See all available top hotels, or vacation rentals in St. Charles.
If I need to cancel my hotel reservation in St. Charles, will I receive a refund?
Yes! The majority of room reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in St. Charles.
What's it like to stay in St. Charles?
Visitors can enjoy all that St. Charles has to offer, including its parks. This city also attracts tourists with its welcoming locals. In St. Charles, there are 3 hotels and other accommodation options to choose from. Find out more about St. Charles.
What is there to see in St. Charles?
A couple of favourite places to visit are Whitewater State Park and Whitewater River. You'll also find Regional Sports Center and National Volleyball Center in the area. Take a look at what more there is to see and do in Expedia's St. Charles guide.
What's the weather like in St. Charles?
The hottest months are usually July and August, with an average temperature of 19°C, while the coldest months are January and February, with an average of -6°C. The snowiest months in St. Charles are January, March, February and April, with each month seeing an average of 20 cm of snowfall.

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