Search Business Hotels in Downtown San Diego

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Check availability on Downtown San Diego Business Hotels

Tonight
7 Dec - 8 Dec
Tomorrow
8 Dec - 9 Dec
Next weekend
12 Dec - 14 Dec
In two weeks
19 Dec - 21 Dec

Top Downtown San Diego Business Hotels

Outdoor pool, pool loungers
Hilton San Diego Bayfront

Hilton San Diego Bayfront

4.0 star property
Downtown San Diego
8.6 out of 10, Excellent, (1852)
"Enjoyed my stay"
United States
Brandon
The price is ₹7,289
₹12,871 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hilton San Diego Bayfront
Hypo-allergenic bedding, in-room safe, desk, iron/ironing board
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (2871)
"It was nice and the bar up top was great"
United States
Brent
The price is ₹15,839
₹23,268 total
includes taxes & fees
14 Dec - 15 Dec
Manchester Grand Hyatt San Diego
Standard Room, 1 King Bed, Non Smoking, Bay View | Premium bedding, pillow-top beds, in-room safe, desk
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3.0 star property
Downtown San Diego
8.8 out of 10, Excellent, (718)
"Great little boutique hotel ! Friendly staff as well"
Canada
Caroll
The price is ₹9,287
₹10,768 total
includes taxes & fees
15 Dec - 16 Dec
The DEXTRO Little Italy, BW Premier Collection
Lobby
Hotel Republic San Diego, Autograph Collection

Hotel Republic San Diego, Autograph Collection

4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (1181)
"Amazing stay "
United States
Aaron
The price is ₹11,492
₹17,500 total
includes taxes & fees
23 Dec - 24 Dec
Hotel Republic San Diego, Autograph Collection
2 outdoor pools, open 6 AM to 10:00 PM, pool cabanas (surcharge)
Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina

4.0 star property
Downtown San Diego
9.2 out of 10, Wonderful, (1940)
"Great hotel"
United States
Farzana
The price is ₹14,309
₹21,323 total
includes taxes & fees
18 Dec - 19 Dec
Marriott Marquis San Diego Marina
Meeting facility
The Westin San Diego Bayview

The Westin San Diego Bayview

4.0 star property
Downtown San Diego
8.6 out of 10, Excellent, (1050)
"I loved the hotel rooms bar area jacuzzi area everything was great it was in a pretty location will definitely come back "
United States
Alliyah
The price is ₹12,167
₹16,716 total
includes taxes & fees
19 Dec - 20 Dec
The Westin San Diego Bayview
Terrace/patio
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4.0 star property
Downtown San Diego
8.4 out of 10, Very good, (6074)
"Always an amazing stay"
United States
Jana
The price is ₹12,162
₹16,712 total
includes taxes & fees
10 Dec - 11 Dec
Wyndham San Diego Bayside
Exterior
San Diego Marriott Gaslamp Quarter

San Diego Marriott Gaslamp Quarter

4.0 star property
Downtown San Diego
8.6 out of 10, Excellent, (1590)
"All was very nice!"
United States
Tim
The price is ₹12,927
₹14,989 total
includes taxes & fees
14 Dec - 15 Dec
San Diego Marriott Gaslamp Quarter
Lobby sitting area
Omni San Diego Hotel at the Ballpark

Omni San Diego Hotel at the Ballpark

4.0 star property
Downtown San Diego
9.2 out of 10, Wonderful, (2044)
"It was an amazing stay "
United States
Alejandra
The price is ₹16,753
₹23,494 total
includes taxes & fees
4 Jan - 5 Jan 2026
Omni San Diego Hotel at the Ballpark
Outdoor pool, pool umbrellas, pool loungers
Hampton Inn San Diego-Downtown

Hampton Inn San Diego-Downtown

2.5 star property
Downtown San Diego
8.2 out of 10, Very good, (2268)
"Great stay, I recommend it"
United States
Furio
The price is ₹9,334
₹10,823 total
includes taxes & fees
21 Dec - 22 Dec
Hampton Inn San Diego-Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Downtown San Diego Hotel Reviews

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

10/10 Excellent
"The room was pretty great there was a nice view of the town, but we could see homeless people in tents sleeping, so there was that. Front desk was amazing. The bar downstairs was great my husband went down and had a drink and watched some sports. Overall a great trip: for a three-star hotel, it was fantastic! Price of room was average, but the parking was a little much at $37.50 for one 24 hour peri[parking fr 9:00 p.m. to 5:00 a.m. was steep."
Jennifer 1-night trip
Posted 1 day ago
The DEXTRO Little Italy, BW Premier Collection

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Frequently asked questions

Why book your business-friendly hotel in Downtown San Diego with Expedia?
Expedia is here to help you find a fantastic business-friendly hotel when work takes you out of town. From free parking and WiFi to on-site restaurants and cafés, our stays come with all you'll need to settle that big contract.
How can I find cheap business-friendly hotels in Downtown San Diego?
Expedia can help you easily find cheap business-friendly hotels in Downtown San Diego. Head to our "traveller experience" filter and click on "business friendly." This will show you stays with amenities designed to help you work and rest comfortably, like free WiFi and included breakfast. You can also choose your budget and hotel star rating to keep costs down.