A calm lake reflecting trees with autumn foliage, a clear sky, and a distant shoreline.

Search Luxury Hotels in St. Charles

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on St. Charles Luxury Hotels

Tonight
29 Sept - 30 Sept
Tomorrow
30 Sept - 1 Oct
This weekend
2 Oct - 4 Oct
Next weekend
9 Oct - 11 Oct

Our top choices for St. Charles luxury hotels

An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.
A bar area with multiple seating arrangements, a stage, and a chandelier.
A modern tavern with a large sign, glass doors, and indoor seating visible through the windows.
A grand lobby with a central chandelier, multiple levels, and rows of liquor bottles.

1. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
St. Charles
  • Indulge in lavish comfort at this St. Charles retreat featuring a full-service spa, seasonal pool, and 6 exceptional restaurants.
₹14,326
₹18,335 total
includes taxes & fees
13 Oct - 14 Oct
Ameristar Casino Resort and Spa
An indoor dining area with a long table, chairs, hanging plants, and a view of a brick building through large windows.
A lobby with a fireplace, two armchairs, a round table, and a bench.
A bar area with leather seating, a bar counter, and shelves of bottles.
An outdoor seating area with modern furniture, a bar, and large windows offering views of a cityscape.

2. The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
Clayton
  • Ritz-Carlton elegance defines this St. Louis retreat with indulgent spa services and dining excellence.
₹59,417
₹69,362 total
includes taxes & fees
26 Oct - 27 Oct
The Ritz-Carlton, St. Louis
A spacious lobby with a brown leather sofa, multiple chairs, a coffee table with a skull decoration, and a large chandelier.
A hotel room with orange furniture, a glass coffee table, a dining area with a table and chairs, and a patterned carpet.
A hotel room with a large bed, a desk with a chair, a television, a mirror, and a wardrobe.
An indoor tennis court with multiple courts, a net, and players.

3. DoubleTree by Hilton Hotel St. Louis - Chesterfield

DoubleTree by Hilton Hotel St. Louis - Chesterfield
Chesterfield
  • Chesterfield hotel offers plush comforts with indoor tennis courts, dual pools, and premium bedding.
₹13,302
₹15,429 total
includes taxes & fees
25 Oct - 26 Oct
DoubleTree by Hilton Hotel St. Louis - Chesterfield
A modern hotel lobby with a glass facade, seating area, and a staircase.
A bar area with a bartender, a bar counter with various bottles, and a view of the Gateway Arch.
A room with large windows overlooking a bridge and water, featuring wooden chairs and a small table.
A modern dining area with a long table set for a meal, large windows offering a view of a bridge, and a stone accent wall.

4. Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
Downtown St. Louis
  • Lavish riverside luxury awaits at the Four Seasons St. Louis with spa indulgences and poolside bliss.
₹35,933
₹42,016 total
includes taxes & fees
7 Oct - 8 Oct
Four Seasons Hotel St Louis
A restaurant with round tables and chairs, a bar area, and a patterned ceiling.
A Drury Plaza Hotel with a large parking lot and multiple cars parked in front.
A spa bath with a sign indicating a capacity of 8 persons.
A lobby with a reception desk, seating area with sofas and ottomans, and a patterned rug.

5. Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood
Brentwood
₹13,031
₹15,471 total
includes taxes & fees
11 Oct - 12 Oct
Drury Plaza Hotel St. Louis Brentwood
A hotel with a swimming pool, lounge chairs, and a courtyard with palm trees.
A bar area with a marble counter, bar stools, and a variety of liquor bottles.
An outdoor patio with a brick fireplace, wicker furniture, and a dining table set with food and drinks.
A grand lobby with a central seating area, a staircase, and a decorative ceiling.

6. The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
Central West End
  • Indulge in historic elegance at this St. Louis gem featuring 3 restaurants, a spectacular pool area, and luxurious rooms near Forest Park.
₹14,590
₹20,036 total
includes taxes & fees
4 Oct - 5 Oct
The Royal Sonesta Chase Park Plaza St. Louis
A modern hotel room with a large bed, a nightstand, a mirror, and a view of the city through arched windows.
A modern restaurant interior with high tables, chairs, and a central bar area.
A lobby with wooden paneling, a green wall, and two armchairs.
A bar area with wooden paneling, a counter, and multiple stools.

7. The Westin St. Louis

The Westin St. Louis
Downtown St. Louis
  • Opulent city centre retreat with pillowtop beds, soaking tubs, and Italian dining moments from Busch Stadium.
₹12,587
₹14,718 total
includes taxes & fees
18 Oct - 19 Oct
The Westin St. Louis
A multi-story building with a symmetrical facade, large windows, and a central entrance with a canopy.
A reception area with a curved wooden desk, a laptop, and a chair. The wall has a sign reading "Locust Street Athletic and Swim Club."
A reception desk with a wooden finish and the name "IDOL WOLF" on it.
A spacious lobby with a large spherical sculpture, a seating area, and a view of the outside through a large window.

8. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
Downtown West
  • Indulge in artistic luxury at this city centre St. Louis hotel with spa services and indoor pool.
₹13,765
₹16,574 total
includes taxes & fees
25 Oct - 26 Oct
21C Museum Hotel St Louis
A bar area with wooden tables, leather seating, and a bar counter.
A large white building with a central tower, a parking lot, and a tree with red leaves.
A bar area with a wooden counter, hanging glasses, and a liquor display.
A covered outdoor area with two tables and two chairs, a white railing, and a view of a road and trees.

9. The Inn at Elijah McLeans

The Inn at Elijah McLeans
Washington
₹12,936
₹14,728 total
includes taxes & fees
30 Sept - 1 Oct
The Inn at Elijah McLeans
View all properties

Top St. Charles Hotel Reviews

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

10/10 Excellent
"Write a review and help other travelers plan better. Ideas to write about: Clean room Staff Breakfast Laundry Whether it was amazing or not-so-good, your experience helps other travellers make their choice. Details about cleanliness are especially helpful. Minimum 25 characters 0/1500 Next We were very pleased with everything with our stay. The room was great as was the tub and shower.They have wonderful breakfast buffet with a huge variety of items to choose froom."
William 2-night trip
Posted 1 hour ago
Clayton Plaza Hotel & Extended Stay
Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District

8/10 Good
"nice size free parking spots in the garage. Breakfast was slim. one morning just had sausage and eggs and waffles. next morning had biscuits and gravy and waffles. hotel was clean staffing was friendly. location was good. The cookies were delicious."
Scott 2-night trip
Posted 11 hours ago
Country Inn & Suites by Radisson, St. Charles Historic District
Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis Union Station

10/10 Excellent
"You should use a lot of taxies."
spandana 2-night trip
Posted 12 hours ago
Drury Plaza Hotel St. Louis Union Station
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

10/10 Excellent
"Very nice hotel. Staff very friendly."
Cynthia 1-night trip
Posted 16 hours ago
Ameristar Casino Resort and Spa
Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles

10/10 Excellent
"Cory greeted me well before our check in time, allowed me to drop bags. I asked for some time to do work and needed WiFi, he said he couldn’t unless I was a Hilton honors member and helped me create. Also gave me a breakfast pass even thought we weren’t officially checked in. Very accommodating to our needs. Great stay! Would very much go back again!"
James 4-night trip
Posted 18 hours ago
Embassy Suites by Hilton St. Louis St. Charles
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

8/10 Good
"I would go back and stay again because the overall experience was good."
Sai Krishna 1-night trip
Posted 23 hours ago
Pear Tree Inn St. Louis Near Union Station
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

10/10 Excellent
"Great stay with a great view and amenities…."
Laura 3-night trip
Posted 1 day ago
Hyatt Regency St. Louis at The Arch
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

10/10 Excellent
"Staff was great! Would come back to stay."
Isaac 4-night trip
Posted 2 days ago
Renaissance St. Louis Airport Hotel

Frequently asked questions

Are you looking for a luxury hotel for your stay in St. Charles?
During your visit, you might want to enjoy the casinos and shopping which St. Charles is known for.
What's the best luxury hotel in St. Charles?
Ameristar Casino Resort and Spa is a luxury hotel with 6 restaurants and 2 bars, and it's a popular choice for Expedia travellers looking for an elegant place to stay.
When can I expect good weather in St. Charles?
Planning for the weather is an important factor for making your trip to St. Charles a success, especially when you're splurging. The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for St. Charles is 1172 mm.
What's there to see and do in St. Charles?
When you're in St. Charles, enjoy exploring the sights and attractions here including Historic Main Street, Katy Trail and Lewis & Clark Boathouse and Nature Center. If you have a little extra time during your trip, you might want to make a stop at St Charles Convention Center and Ameristar Casino St. Charles.

Explore a world of travel with Expedia