TOP Business Hotels in St. Louis, MO for 2026

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Our top choices for St. Louis business-friendly hotels

A well-lit lobby with a chandelier, potted plants, and a seating area.

1. Truitt Hotel

Lafayette Square

Gabrielle

₹19,365 total

includes taxes & fees

3 Nov - 4 Nov

A rooftop terrace with rows of metal chairs and a view of city buildings.

2. Drury Plaza Hotel St. Louis at the Arch

Downtown St. Louis

Nicole

₹15,987 total

includes taxes & fees

9 Nov - 10 Nov

A modern outdoor lounge area with seating, a bar, and a view of a cityscape.

3. Live by Loews - St.Louis

Downtown St. Louis

brandon

₹15,697 total

includes taxes & fees

15 Nov - 16 Nov

A modern hotel lobby with a glass facade, seating area, and a staircase.

4. Four Seasons Hotel St Louis

Downtown St. Louis

JEFFREY

₹41,636 total

includes taxes & fees

3 Nov - 4 Nov

A multi-story building with a grand entrance, large windows, and a well-lit facade at night.

5. Grand Center Inn

Grand Center

Leon and Janis

₹18,842 total

includes taxes & fees

3 Nov - 4 Nov

An outdoor seating area with multiple tables and chairs, large umbrellas, and a built-in fire feature against a stone wall.

6. Fairfield Inn & Suites by Marriott St. Louis Downtown

Downtown West

Demarco

₹13,373 total

includes taxes & fees

22 Nov - 23 Nov

A multi-story building with a classic architectural style, featuring numerous windows and a brick facade.

7. Courtyard by Marriott St. Louis Downtown/Convention Center

Downtown St. Louis

CESAR

₹10,943 total

includes taxes & fees

23 Nov - 24 Nov

A modern lobby with a large glass sphere, seating areas, and a reception desk.

8. 21C Museum Hotel St Louis

Downtown West

A.R.

₹16,424 total

includes taxes & fees

22 Nov - 23 Nov

9. Pear Tree Inn St. Louis Near Union Station

Downtown West

Larry

₹11,546 total

includes taxes & fees

15 Nov - 16 Nov

A multi-story hotel with a prominent corner location, large windows, and a well-lit facade.

10. Embassy Suites by Hilton St. Louis Downtown

Downtown St. Louis

Megan

₹12,863 total

includes taxes & fees

23 Nov - 24 Nov

An indoor swimming pool with clear glass ceilings, large windows, and a sunlit area with umbrellas.

11. Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Downtown St. Louis

Andrew

₹11,745 total

includes taxes & fees

22 Nov - 23 Nov

A spacious lobby with high ceilings, ornate columns, and a blue patterned carpet.

12. St. Louis Union Station Hotel, Curio Collection by Hilton

Downtown West

William

₹17,502 total

includes taxes & fees

22 Nov - 23 Nov

A spacious lobby with modern seating arrangements, a large chandelier, and a view of the cityscape through large windows.

13. Hilton Pennywell St. Louis at the Arch

Downtown St. Louis

Tabitha

₹12,174 total

includes taxes & fees

15 Nov - 16 Nov

An outdoor patio area with seating, planters, and a grill.

14. Element by Marriott St. Louis Midtown

Midtown

Julie

₹15,877 total

includes taxes & fees

15 Nov - 16 Nov

A spacious lobby with a polished floor, a large chandelier, and a central table with a potted plant.

15. Missouri Athletic Club

Downtown St. Louis

Heather

₹17,387 total

includes taxes & fees

3 Nov - 4 Nov

A rooftop terrace with outdoor seating, string lights, and a city skyline view.

16. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Grand Center

Gregory

₹11,572 total

includes taxes & fees

22 Nov - 23 Nov

A grand lobby with a large chandelier, a bar area, and classical architecture.

17. Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Downtown St. Louis

Anastasia

₹10,728 total

includes taxes & fees

23 Nov - 24 Nov

A grand lobby with a high ceiling, ornate chandeliers, and a central seating area with blue upholstered chairs.

18. Hotel Saint Louis, Autograph Collection

Downtown St. Louis

Shawn

₹19,086 total

includes taxes & fees

15 Nov - 16 Nov

A modern outdoor seating area with a fire pit, surrounded by wicker furniture and a landscaped garden.

19. Courtyard by Marriott St. Louis Downtown West

Downtown West

nadia

₹12,891 total

includes taxes & fees

15 Nov - 16 Nov

A lobby with a sofa, two armchairs, a coffee table, and a staircase.

20. Hyatt Regency St. Louis at The Arch

Downtown St. Louis

Tracy

₹14,009 total

includes taxes & fees

25 Nov - 26 Nov

View all properties

Top St. Louis Hotel Reviews

Moonrise Hotel

10/10 Excellent

"Cool hotel!"

Courtyard by Marriott St. Louis Downtown/Convention Center

8/10 Good

"It was a great hotel with lovely service, clean rooms, good water pressure, extremely hot water available, soft towels, and helpful staff. The only problems I had were that the parking garage was a block over from the hotel so anytime we wanted to go anywhere, we had to walk to the next street over. It wasn’t a big deal but a slight inconvenience especially if you’re in a rush. There is a place to eat downstairs that has things like muffins, coffee, and real meals BUT it’s only open from 5pm-10pm? Just inconvenient times. Other than those things, it was great."

Frequently asked questions

How much do business-friendly hotels in St. Louis cost?

You can expect to pay between ₹7,774 and ₹15,987 per night for business-friendly hotels in St. Louis. Awesome deals on properties that are suitable for work-related guests are just a few clicks away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.

What are the best business-friendly hotels in St. Louis?

A lot of corporate travellers recommend Drury Inn & Suites St. Louis Brentwood. This 3-stars property offers amenities such as a swimming pool and WiFi. Drury Plaza Hotel St. Louis at the Arch is another sought-after option. It has a 3-stars rating and conveniences including a swimming pool and a terrace. You'll have your pick of multiple business-friendly hotels in St. Louis that have a total average guest review rating of 9.2.

How many business-friendly hotels are there in St. Louis?

When your job takes you on the road in St. Louis, you'll have 195 business-friendly hotels to pick from. These stays offer a well-suited location with the conveniences corporate travellers need.

What are the best cheap business-friendly hotels in St. Louis?

Save money on your work trip to St. Louis by choosing one of our business-friendly hotels that start from only ₹7,774 per night. One inexpensive property is Hampton Inn & Suites St. Louis at Forest Park, which comes with amenities like a swimming pool and pillow top mattresses. Hampton Inn St. Louis-Downtown (At the Gateway Arch) is another leading pick for corporate travellers with a tight budget. It features pool sun loungers and an electric car charging station. However, your St. Louis visit shouldn't be all work and no play. Explore some fun and free attractions, such as Forest Park and Anheuser-Busch Brewery. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.

Are there any family-friendly hotels in St. Louis that are also business friendly?

Drury Plaza Hotel St. Louis at the Arch is popular with both business and leisure guests. Complimentary breakfast and WiFi are just a couple of the amenities available at this 3-stars St. Louis escape. Alternatively, holiday with the family and get down to work at Drury Inn & Suites St. Louis Forest Park. Enjoy the use of conveniences such as complimentary breakfast and housekeeping services at this top 3-stars option. St. Louis has tons of family-friendly attractions to check out when you're done with work. Take the kids on an outing to St. Louis Zoo and Forest Park.

Are there any 5-star business-friendly hotels in St. Louis?

St. Louis has some great 5-star options for corporate guests. Enjoy luxury perks after a busy day with clients at Four Seasons Hotel St Louis. Amenities at this business-friendly stay, around 2 kilometres from St. Louis's centre, include a sauna and treatment rooms. Another high-end property that has everything you need for a work trip is The Ritz-Carlton, St. Louis. It features designer toiletries and concierge services and is 11 kilometres from the downtown area.

Why book your business-friendly hotel in St. Louis with Expedia?

With useful amenities like conference rooms, 24-hour front desk support and free parking, our business-friendly hotels come with all you'll need to settle that big contract — and then relax in the comfort of your room. Enter your preferred dates and travel destination and Expedia will help you plan the rest.

How can I find cheap business-friendly hotels in St. Louis?

Select the "business friendly" filter, listed just under the "traveller experience" heading, to find cheap business-friendly hotels in St. Louis. Then narrow your search by your budget and preferred hotel star rating. Looking for stays away from the centre is another easy way to save.

What is there to do in St. Louis near my business-friendly hotel?

Whatever you love to do, St. Louis has a whole lot to keep you on the go. St. Louis Zoo, Forest Park and Fox Theatre are on most visitors' sightseeing plans. Don't head home without exploring Anheuser-Busch Brewery, St. Louis Aquarium at Union Station and St. Louis Science Centre either. With Expedia's business-friendly hotel deals, you can discover more renowned attractions like these with the cash you save.

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Check availability on St. Louis Business Hotels

Our top choices for St. Louis business-friendly hotels

1. Truitt Hotel

2. Drury Plaza Hotel St. Louis at the Arch

3. Live by Loews - St.Louis

4. Four Seasons Hotel St Louis

5. Grand Center Inn

6. Fairfield Inn & Suites by Marriott St. Louis Downtown

7. Courtyard by Marriott St. Louis Downtown/Convention Center

8. 21C Museum Hotel St Louis

9. Pear Tree Inn St. Louis Near Union Station

10. Embassy Suites by Hilton St. Louis Downtown

11. Hampton Inn St. Louis-Downtown (At the Gateway Arch)

12. St. Louis Union Station Hotel, Curio Collection by Hilton

13. Hilton Pennywell St. Louis at the Arch

14. Element by Marriott St. Louis Midtown

15. Missouri Athletic Club

16. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

17. Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

18. Hotel Saint Louis, Autograph Collection

19. Courtyard by Marriott St. Louis Downtown West

20. Hyatt Regency St. Louis at The Arch

Top St. Louis Hotel Reviews

Moonrise Hotel

Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis at the Arch

Clayton Plaza Hotel & Extended Stay

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hollywood Casino & Hotel St. Louis

Pear Tree Inn St. Louis Airport

Courtyard by Marriott St. Louis Downtown/Convention Center

Frequently asked questions

Explore a world of travel with Expedia

Search Business Hotels in St. Louis

Change your mind

Treat yourself

Be picky

Check availability on St. Louis Business Hotels

Our top choices for St. Louis business-friendly hotels

1. Truitt Hotel

2. Drury Plaza Hotel St. Louis at the Arch

3. Live by Loews - St.Louis

4. Four Seasons Hotel St Louis

5. Grand Center Inn

6. Fairfield Inn & Suites by Marriott St. Louis Downtown

7. Courtyard by Marriott St. Louis Downtown/Convention Center

8. 21C Museum Hotel St Louis

9. Pear Tree Inn St. Louis Near Union Station

10. Embassy Suites by Hilton St. Louis Downtown

11. Hampton Inn St. Louis-Downtown (At the Gateway Arch)

12. St. Louis Union Station Hotel, Curio Collection by Hilton

13. Hilton Pennywell St. Louis at the Arch

14. Element by Marriott St. Louis Midtown

15. Missouri Athletic Club

16. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

17. Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

18. Hotel Saint Louis, Autograph Collection

19. Courtyard by Marriott St. Louis Downtown West

20. Hyatt Regency St. Louis at The Arch

Top St. Louis Hotel Reviews

Moonrise Hotel

Frequently asked questions

Explore a world of travel with Expedia