A marina with boats docked, a city skyline with high-rise buildings, and a sunset with pink and orange clouds.

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Check prices for these dates

This weekend
13 Nov - 15 Nov
Next weekend
20 Nov - 22 Nov

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Our top choices for Otay Mesa West hotels

A spacious lobby with a fireplace, wooden furniture, and a chandelier.

1. Best Western Americana Inn

Best Western Americana Inn
2.5 star property
2.1 km from Otay Mesa West
8.8 out of 10, Excellent, (1,431 reviews)
"Great service from the staff!"
United States
Erika
The price is ₹9,837
₹11,189 total
includes taxes & fees
22 Nov - 23 Nov
Best Western Americana Inn
A buffet with various food items, including omelets and other dishes, served in metal trays.

2. Holiday Inn Express San Diego South - Chula Vista by IHG

Holiday Inn Express San Diego South - Chula Vista by IHG
2.5 star property
8 km from Otay Mesa West
9.4 out of 10, Exceptional, (1,655 reviews)
"Great stay"
United States
Daniel
The price is ₹14,936
₹16,429 total
includes taxes & fees
10 Dec - 11 Dec
Holiday Inn Express San Diego South - Chula Vista by IHG
A hotel lobby with a patterned carpet, a reception desk, a sofa with cushions, and potted plants.

3. Comfort Inn Chula Vista San Diego South

Comfort Inn Chula Vista San Diego South
2.5 star property
7.9 km from Otay Mesa West
8.4 out of 10, Very good, (1,727 reviews)
"It was a nice hotel. I’d stay here again."
United States
Lori
The price is ₹10,230
₹11,273 total
includes taxes & fees
29 Nov - 30 Nov
Comfort Inn Chula Vista San Diego South
A spacious lobby with a modern design, featuring a large seating area, a reception desk, and large windows offering views of the city.

4. Ayres Hotel San Diego South - Chula Vista

Ayres Hotel San Diego South - Chula Vista
3.0 star property
9.2 km from Otay Mesa West
9.8 out of 10, Exceptional, (1,027 reviews)
"I was very impressed with this hotel. The rooms were comfortable and modern and the staff was warm and welcoming."
United States
Rosemary
The price is ₹16,609
₹18,302 total
includes taxes & fees
13 Dec - 14 Dec
Ayres Hotel San Diego South - Chula Vista
A breakfast bar with La Quinta branding, a coffee machine, and a waffle display.

5. La Quinta Inn by Wyndham San Diego Chula Vista

La Quinta Inn by Wyndham San Diego Chula Vista
3.0 star property
7.8 km from Otay Mesa West
8.6 out of 10, Excellent, (1,791 reviews)
"Clean room , friendly staff , always helpful, breakfast good , always great to return"
United States
Luis
The price is ₹9,661
₹10,627 total
includes taxes & fees
29 Nov - 30 Nov
La Quinta Inn by Wyndham San Diego Chula Vista
A modern hotel with a prominent 'Hercor Hotel' sign, multiple balconies, and a 'Urban Boutique' label.

6. Hercor Hotel - Urban Boutique

Hercor Hotel - Urban Boutique
3.0 star property
6.8 km from Otay Mesa West
8.8 out of 10, Excellent, (1,581 reviews)
"Really nice place"
United States
justin
The price is ₹10,431
₹11,494 total
includes taxes & fees
18 Nov - 19 Nov
Hercor Hotel - Urban Boutique
A spacious restaurant with high ceilings, exposed beams, and hanging plants. There are multiple seating areas with tables and chairs.

7. Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel
3.5 star property
10.4 km from Otay Mesa West
9.2 out of 10, Wonderful, (4,224 reviews)
"Clean room and really nice area for our stay"
United States
Brandon
The price is ₹12,598
₹13,882 total
includes taxes & fees
29 Nov - 30 Nov
Best Western Plus Marina Gateway Hotel
A retro-themed arcade with classic games, a foosball table, and a long communal table with stools.

8. The Rambler Hotel

The Rambler Hotel
3.0 star property
8 km from Otay Mesa West
9.0 out of 10, Wonderful, (2,208 reviews)
"Very nice retro hotel. Near highway and lots of restaurants. Would stay there again. Great coffee."
United States
Mark S.
The price is ₹8,719
₹10,087 total
includes taxes & fees
19 Nov - 20 Nov
The Rambler Hotel
A hotel room with a bed, a desk with a chair, a nightstand, and a wall-mounted TV displaying a sunset scene.

9. Hotel Palmeras Chula Vista

Hotel Palmeras Chula Vista
2.0 star property
7.8 km from Otay Mesa West
7.4 out of 10, Good, (2,470 reviews)
"Clean rooms nice staff"
United States
Wendy
The price is ₹6,032
₹6,636 total
includes taxes & fees
18 Nov - 19 Nov
Hotel Palmeras Chula Vista
An outdoor seating area with fire pits, lounge chairs, and string lights against a sunset backdrop.

10. Loews Coronado Bay Resort

Loews Coronado Bay Resort
4.0 star property
9.6 km from Otay Mesa West
9.0 out of 10, Wonderful, (1,166 reviews)
"Lovely place to stay, beautiful scenery. The only downside is everything is far away- gas station, restaurants, you have to UBER or have a rental car to travel for amenities outside of what the resort offers."
United States
Josh
The price is ₹15,889
₹22,587 total
includes taxes & fees
13 Dec - 14 Dec
Loews Coronado Bay Resort
A modern kitchen area with a self-serve station, including a waffle maker, coffee machine, and various food items.

11. Best Western Chula Vista/Otay Valley Hotel

Best Western Chula Vista/Otay Valley Hotel
2.5 star property
2.4 km from Otay Mesa West
8.0 out of 10, Very good, (2,035 reviews)
"Me and my husband loved it we tried different ones and this one is one of the best from now on is going to be our favorite to stay,very clean and breakfast was so good so many options for breakfast"
United States
Edna
The price is ₹10,300
₹11,350 total
includes taxes & fees
22 Nov - 23 Nov
Best Western Chula Vista/Otay Valley Hotel
View from property

12. SpringHill Suites by Marriott Chula Vista Eastlake

SpringHill Suites by Marriott Chula Vista Eastlake
3.5 star property
12.4 km from Otay Mesa West
9.6 out of 10, Exceptional, (825 reviews)
"Great hotel"
United States
leslie
The price is ₹15,269
₹16,826 total
includes taxes & fees
6 Dec - 7 Dec
SpringHill Suites by Marriott Chula Vista Eastlake
A high-rise building complex with multiple floors, large windows, and a waterfront view.

13. Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego
4.0 star property
Marina District, 18.2 km from Otay Mesa West
9.0 out of 10, Wonderful, (2,899 reviews)
"Beautiful hotel would stay again!"
United States
Petra
The price is ₹15,700
₹23,322 total
includes taxes & fees
9 Dec - 10 Dec
Manchester Grand Hyatt San Diego
A swimming pool with palm trees and a mountain in the background.

14. Sycuan Casino Resort

Sycuan Casino Resort
4.0 star property
31.2 km from Otay Mesa West
9.4 out of 10, Exceptional, (2,222 reviews)
"Great stay!"
United States
Kimberly
The price is ₹8,543
₹10,525 total
includes taxes & fees
16 Nov - 17 Nov
Sycuan Casino Resort
A hotel room with a large window offering a city view, a bed, a chair, and a small table.

15. The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection
3.0 star property
19.1 km from Otay Mesa West
8.8 out of 10, Excellent, (2,369 reviews)
"Really enjoyed my stay!"
United States
Kelly
The price is ₹11,866
₹13,758 total
includes taxes & fees
18 Nov - 19 Nov
The DEXTRO Little Italy, BW Premier Collection
A modern hotel with a courtyard featuring outdoor seating, a chess table, and a well-maintained lawn.

16. Hampton Inn & Suites by Hilton San Diego SeaWorld Near Old Town

Hampton Inn & Suites by Hilton San Diego SeaWorld Near Old Town
4.0 star property
24.3 km from Otay Mesa West
9.2 out of 10, Wonderful, (1,487 reviews)
"The breakfast was amazing!"
United States
David
The price is ₹14,292
₹16,428 total
includes taxes & fees
17 Nov - 18 Nov
Hampton Inn & Suites by Hilton San Diego SeaWorld Near Old Town
A multi-story hotel with a brick facade, multiple windows, and a fire escape.

17. The Sofia Hotel

The Sofia Hotel
3.5 star property
18.5 km from Otay Mesa West
8.8 out of 10, Excellent, (2,777 reviews)
"Great location, clean rooms, friendly staff."
United States
Randy
The price is ₹10,523
₹14,500 total
includes taxes & fees
7 Dec - 8 Dec
The Sofia Hotel
A hotel with a Holiday Inn Express sign, a modern building with balconies, and a view of the city skyline at night.

18. Holiday Inn Express San Diego Downtown by IHG

Holiday Inn Express San Diego Downtown by IHG
2.5 star property
18.6 km from Otay Mesa West
8.4 out of 10, Very good, (1,718 reviews)
"It was a good place to stay"
United States
Angel
The price is ₹12,648
₹14,665 total
includes taxes & fees
10 Dec - 11 Dec
Holiday Inn Express San Diego Downtown by IHG
A breakfast buffet area with a stone wall, a coffee station, and a fruit display.

19. Hampton Inn San Diego-Kearny Mesa

Hampton Inn San Diego-Kearny Mesa
2.5 star property
29.7 km from Otay Mesa West
9.2 out of 10, Wonderful, (1,013 reviews)
"Fantastic hotel with very friendly staff"
United States
Jeffrey
The price is ₹10,220
₹11,728 total
includes taxes & fees
11 Dec - 12 Dec
Hampton Inn San Diego-Kearny Mesa
A hotel lobby with a waterfall feature, outdoor seating area, and multiple floors with balconies.

20. Crowne Plaza San Diego - Mission Valley by IHG

Crowne Plaza San Diego - Mission Valley by IHG
3.5 star property
23.7 km from Otay Mesa West
8.4 out of 10, Very good, (1,498 reviews)
"Had a good stay"
United States
Yesenia
The price is ₹10,681
₹12,312 total
includes taxes & fees
18 Nov - 19 Nov
Crowne Plaza San Diego - Mission Valley by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Otay Mesa West

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A spacious lobby with a fireplace, wooden furniture, and a chandelier.
Best Western Americana Inn
2.5 star property
8.8
Excellent
1,431 reviews
View
A buffet with various food items, including omelets and other dishes, served in metal trays.
Holiday Inn Express San Diego South - Chula Vista by IHG
2.5 star property
9.4
Exceptional
1,655 reviews
View
A spacious lobby with a modern design, featuring a large seating area, a reception desk, and large windows offering views of the city.
Ayres Hotel San Diego South - Chula Vista
3.0 star property
9.8
Exceptional
1,027 reviews
View
A breakfast bar with La Quinta branding, a coffee machine, and a waffle display.
La Quinta Inn by Wyndham San Diego Chula Vista
3.0 star property
8.6
Excellent
1,791 reviews
View
A retro-themed arcade with classic games, a foosball table, and a long communal table with stools.
The Rambler Hotel
3.0 star property
9.0
Wonderful
2,208 reviews
View

Hotels recommended for families in Otay Mesa West

A spacious lobby with a fireplace, wooden furniture, and a chandelier.

Best Western Americana Inn

Best Western Americana Inn
2.5 star property
San Ysidro
8.8 out of 10, Excellent, (1,431)
The price is ₹9,837
₹11,189 total
includes taxes & fees
22 Nov - 23 Nov
Best Western Americana Inn

Where to stay in Otay Mesa West

Find the best Otay Mesa West areas for the activities you enjoy most. Learn more about Otay Mesa West
Learn more about Otay Mesa West
A large stadium with the sign "Cobo Park" and palm trees around it.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

A pier extending into the ocean with buildings at the end, under a partly cloudy sky.

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

A theater marquee with ornate designs and the name "Gaslamp Quarter".

Gaslamp Quarter

The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.

A coastal cityscape with a long sandy beach, a pier, and dense urban buildings.

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

An aerial view of a coastal city with a marina, a large body of water, and a peninsula with buildings.

Mission Bay

If you're spending some time in Mission Bay, Mission Bay and Ski Beach are top sights worth seeing.

Top Otay Mesa West Hotel Reviews

Best Western Seven Seas

Best Western Seven Seas

10/10 Excellent
"The pool and jacuzzis are very clean and relaxing. The rooms are comfortable. The staff try their best to accommodate guests with disabilities. I have tried other BW hotels in San Diego. This one is my favorite by far."
Maria 1-night trip
Posted less than an hour ago
Best Western Seven Seas

Frequently asked questions

What is Otay Mesa West like?
Otay Mesa West is a neighbourhood that travellers like for its cathedral.
If I need to cancel my hotel reservation in Otay Mesa West, will I receive a refund?
Yes! The majority of room reservations are refundable if you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of your booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to review top deals in Otay Mesa West.
What is there to do around this San Diego neighbourhood?
A few places to visit in the area around Otay Mesa West include San Ysidro Border Crossing, Las Americas Premium Outlets and Sesame Place San Diego. While you're out sightseeing in San Diego, make sure that you visit other sights such as Tijuana Customs - Garita El Chaparral or North Island Credit Union Amphitheatre.
How can I get around Otay Mesa West and the greater San Diego area?
Ready to get out and explore the city? Iris Avenue Trolley Station is the closest metro station.

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