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Our top choices for Little Italy hotels with a spa

Hilton San Diego Bayfront

Hilton San Diego Bayfront
4.0 star property
Downtown San Diego
8.6 out of 10, Excellent, (1856)
"Enjoyed my stay"
United States
Brandon
The price is ₹7,483
₹13,089 total
includes taxes & fees
3 Jan - 4 Jan 2026
Hilton San Diego Bayfront

Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina
4.0 star property
Mission Bay
8.4 out of 10, Very good, (1570)
"Loved our stay "
United States
Jeremy
The price is ₹10,445
₹16,766 total
includes taxes & fees
16 Dec - 17 Dec
Hyatt Regency Mission Bay Spa and Marina

The Westin San Diego Bayview

The Westin San Diego Bayview
4.0 star property
Downtown San Diego
8.6 out of 10, Excellent, (1060)
"I loved the hotel rooms bar area jacuzzi area everything was great it was in a pretty location will definitely come back "
United States
Alliyah
The price is ₹12,152
₹16,696 total
includes taxes & fees
19 Dec - 20 Dec
The Westin San Diego Bayview

San Diego Mission Bay Resort

San Diego Mission Bay Resort
4.0 star property
Mission Bay
8.4 out of 10, Very good, (1309)
"great stay! Food was great and my kids loved the pool and location"
United States
ANDREA
The price is ₹10,585
₹16,222 total
includes taxes & fees
14 Dec - 15 Dec
San Diego Mission Bay Resort

Loews Coronado Bay Resort

Loews Coronado Bay Resort
4.0 star property
Silver Strand
8.8 out of 10, Excellent, (1066)
"My stay was wonderful! "
United States
Jeanine
The price is ₹16,089
₹22,223 total
includes taxes & fees
19 Dec - 20 Dec
Loews Coronado Bay Resort

Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa
4.0 star property
Mission Valley
9.2 out of 10, Wonderful, (2941)
"Everything was super comfortable and the room was surprisingly affordable for the amenities you get. We will definitely stay there again if we go to San Diego."
United States
Eric
The price is ₹13,676
₹15,720 total
includes taxes & fees
21 Dec - 22 Dec
Legacy Resort Hotel & Spa

Kona Kai San Diego

Kona Kai San Diego
4.0 star property
Point Loma
8.2 out of 10, Very good, (1000)
"had a wonderful time for our honey moon here "
United States
Anna
The price is ₹13,543
₹20,964 total
includes taxes & fees
10 Jan - 11 Jan 2026
Kona Kai San Diego

Best Western Plus Island Palms Hotel & Marina

Best Western Plus Island Palms Hotel & Marina
3.0 star property
Point Loma
8.8 out of 10, Excellent, (1554)
"Every time i have stayed here everything is always clean...no complaints!"
United States
Joseline
The price is ₹10,283
₹11,819 total
includes taxes & fees
5 Jan - 6 Jan 2026
Best Western Plus Island Palms Hotel & Marina

Paradise Point Resort & Spa

Paradise Point Resort & Spa
4.0 star property
Mission Bay
8.6 out of 10, Excellent, (2349)
"Great stay, top tier service and excellent customer care "
Canada
Meriem
The price is ₹11,626
₹18,121 total
includes taxes & fees
21 Dec - 22 Dec
Paradise Point Resort & Spa

Omni San Diego Hotel at the Ballpark

Omni San Diego Hotel at the Ballpark
4.0 star property
Downtown San Diego
9.2 out of 10, Wonderful, (2048)
"It was an amazing stay "
United States
Alejandra
The price is ₹16,733
₹23,465 total
includes taxes & fees
5 Jan - 6 Jan 2026
Omni San Diego Hotel at the Ballpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about Little Italy

Top Little Italy attractions for a relaxing vacation

Little Italy, a vibrant enclave brimming with culture and charm, offers an array of experiences perfect for travellers seeking spa hotels. Begin your day with a leisurely stroll through the historic streets, where the scent of fresh pasta wafts from authentic Italian eateries. Don’t miss the chance to indulge in a culinary class at a local trattoria, learning to make classic dishes while enjoying a glass of fine Italian wine. For art enthusiasts, the nearby San Diego Museum of Art showcases an impressive collection, making for a culturally enriching afternoon. After a day of exploration, unwind at one of the area's luxurious hotels featuring on-site spas, where treatments often incorporate local ingredients, providing a unique sense of place. Imagine soaking in a hot stone massage while gazing out at the charming streets below. In the evening, enjoy an alfresco dinner at a rooftop restaurant, where you can savour exquisite cuisine accompanied by stunning views of the San Diego skyline. With attention to detail and exceptional service, hotels in Little Italy ensure that every aspect of your stay is pampered and enjoyable.

Top Little Italy Hotel Reviews

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Frequently asked questions

Looking to holiday at a spa hotel in Little Italy?
Treat yourself to some pampering and book a hotel with a spa. Travellers highly recommend the restaurants in Little Italy. Enjoy the museums and cafes during your holiday. Spa hotels are a great way to take a break from your routine and add a layer of luxury to your holiday.
What's there to see and do in Little Italy?
When you're in Little Italy, enjoy exploring the sights and attractions here including Maritime Museum of San Diego, San Diego Bay and Star of India. If you have a little extra time during your trip, you might want to make a stop at San Diego Zoo and Port of San Diego.
What is a Little Italy spa hotel?
Spa hotels in Little Italy feature full on-site spas and offer services including couples massages and a range of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are a must if you want to give yourself an extra treat while on holiday.