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South America Accommodation: Most Popular Cities to Stay

Rio de Janeiro featuring general coastal views, mountains and a sunset
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Rio de Janeiro

Rio de Janeiro

Check availability on South America Business Hotels

Tonight
30 Nov - 1 Dec
Tomorrow
1 Dec - 2 Dec
Next weekend
5 Dec - 7 Dec
In two weeks
12 Dec - 14 Dec

Top South America Business Hotels

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Radisson Blu Plaza El Bosque Santiago

Radisson Blu Plaza El Bosque Santiago

4.0 star property
Las Condes
8.8 out of 10, Excellent, (1003)
"clean room, location, breakfast"
United States
Marita de
The price is ₹11,674
₹11,674 total
13 Dec - 14 Dec
Radisson Blu Plaza El Bosque Santiago
Reception
Grand Hyatt Sao Paulo

Grand Hyatt Sao Paulo

5.0 star property
Itaim Bibi
9.4 out of 10, Exceptional, (1011)
"Very nice room. "
United States
Reinaldo
The price is ₹14,059
₹14,762 total
includes taxes & fees
26 Dec - 27 Dec
Grand Hyatt Sao Paulo
Outdoor pool, free pool cabanas, pool umbrellas
Pullman Santiago Vitacura

Pullman Santiago Vitacura

5.0 star property
Vitacura
9.0 out of 10, Wonderful, (907)
"Clean and quiet"
United States
Nathan
The price is ₹5,421
₹5,421 total
31 Dec - 1 Jan 2026
Pullman Santiago Vitacura
Outdoor pool, pool umbrellas, pool loungers
NH Collection Medellín Royal

NH Collection Medellín Royal

5.0 star property
El Poblado
9.2 out of 10, Wonderful, (1015)
"Excellent service, breakfast, room service…."
United States
Mauricio
The price is ₹8,611
₹8,611 total
14 Dec - 15 Dec
NH Collection Medellín Royal
Free daily buffet breakfast
NM Lima Hotel

NM Lima Hotel

4.0 star property
San Isidro
9.2 out of 10, Wonderful, (1007)
"Excelent place, great food, nice people"
United States
Renato
The price is ₹5,815
₹6,396 total
1 Dec - 2 Dec
NM Lima Hotel
Breakfast, lunch, dinner served; Peruvian cuisine
Pullman Lima San Isidro

Pullman Lima San Isidro

4.0 star property
San Isidro
9.2 out of 10, Wonderful, (793)
"."
United States
Daniel
The price is ₹5,904
₹6,495 total
27 Dec - 28 Dec
Pullman Lima San Isidro
Reception
Hotel Plaza El Bosque Ebro

Hotel Plaza El Bosque Ebro

4.0 star property
Las Condes
9.0 out of 10, Wonderful, (1005)
"The breakfast and views were great"
United States
Michael
The price is ₹11,003
₹11,898 total
5 Dec - 6 Dec
Hotel Plaza El Bosque Ebro
Outdoor treatment area, sauna, hot tub, body treatments
Hotel Madero Buenos Aires, WorldHotels Elite

Hotel Madero Buenos Aires, WorldHotels Elite

4.5 star property
Puerto Madero
9.2 out of 10, Wonderful, (1010)
"Spacious room with a view. Clean facility. Courteous staff. Highly recommended!"
United States
Emile
The price is ₹20,853
₹21,121 total
14 Dec - 15 Dec
Hotel Madero Buenos Aires, WorldHotels Elite
Exterior
Regal Pacific Buenos Aires

Regal Pacific Buenos Aires

4.5 star property
El Centro
9.0 out of 10, Wonderful, (1004)
"This is an excellent hotel in Buenos Aires "Microcentro". Good hotel and close by walking distance to Buenos Aires main attractions. Good place to stay also for business purposes."
United States
Jorge
Regal Pacific Buenos Aires
Lobby sitting area
GHL Hotel Capital

GHL Hotel Capital

4.0 star property
Fontibon
9.2 out of 10, Wonderful, (1354)
"CLEAN ROOM EXCELLENT SERVICE GOOD BREAKFAST"
United States
karl
The price is ₹7,171
₹7,171 total
14 Dec - 15 Dec
GHL Hotel Capital
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top South America Hotel Reviews

Amérian Buenos Aires

Amérian Buenos Aires

10/10 Excellent
"It was clean and nice. Me and my brother enjoyed our stay. The staff was also very helpful and pleasant."
Gregory 1-night trip
Posted 3 days ago
Amérian Buenos Aires

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Frequently asked questions

Why book your business-friendly hotel in South America with Expedia?
Here at Expedia, our top task is to help you choose the perfect stay at the right price. From luxurious, corporate-friendly getaways to affordable hotels filled with handy amenities, you'll have your next work trip organised in just a few clicks.
How can I find cheap business-friendly hotels in South America?
When work takes you to South America, our "business friendly" filter will help you find the right hotel. From fast WiFi to meeting rooms and workspaces, they have the amenities you need to do your job. You can also narrow your search by your budget and preferred star rating to view the cheapest properties.