San Luis Obispo Wine Country Luxury Holidays

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Top Luxury San Luis Obispo Wine Country Hotels

Madonna Inn
Madonna Inn
3.5 out of 5
100 Madonna Road, San Luis Obispo, CA
  • 6 min drive from California Polytechnic State University
Stay at this 3.5-star spa hotel in San Luis Obispo. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the pool and the bar in their reviews. ...
9.2/10 Wonderful! (1,182 reviews)
"Amazing, unique experience!"

Reviewed on 2 Jul 2025

Madonna Inn
Avenue Inn Downtown San Luis Obispo
Avenue Inn Downtown San Luis Obispo
2.5 out of 5
345 Marsh St, San Luis Obispo, CA
  • 4 min drive from California Polytechnic State University
Stay at this motel in San Luis Obispo. Enjoy free Wi-Fi, free parking and premium TV channels. Our guests praise the helpful staff and the clean rooms in their ...
9/10 Wonderful! (1,022 reviews)
"The hotel as one of the first as you exit the 101-N and is very convenient. While it's not to far of a walk from downtown, some may want to drive. The staff is friendly and welcoming, the rooms are clean, and the area is quiet."

Reviewed on 2 Jul 2025

Avenue Inn Downtown San Luis Obispo
Avila La Fonda Hotel
Avila La Fonda Hotel
4 out of 5
101 San Miguel St, Avila Beach, CA
  • 22 min drive from California Polytechnic State University
Stay at this 4-star golf hotel in Avila Beach. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular ...
9.4/10 Exceptional! (1,000 reviews)
wonderful
"Had a golf tournament. Love that hotel.. Wish I lived there. How much to stay there for a month?"

Reviewed on 28 Jun 2025

Avila La Fonda Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.