Photo by Rebecca Friedland

Search Hotels Near UCSF Mission Bay, San Francisco

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
5 Dec - 6 Dec
Tomorrow
6 Dec - 7 Dec
This weekend
5 Dec - 7 Dec
Next weekend
12 Dec - 14 Dec

Filter by

Guest rating
Guest rating
Star rating

Top Trending Hotels Near UCSF Mission Bay

Exterior
LUMA Hotel San Francisco

LUMA Hotel San Francisco

4.0 star property
0.7 km from UCSF Mission Bay
9.6 out of 10, Exceptional, (2362)
"Amazing hotel"
United States
Leslie
The price is ₹17,545
₹20,650 total
includes taxes & fees
23 Dec - 24 Dec
LUMA Hotel San Francisco
Lobby
Galleria Park Hotel

Galleria Park Hotel

4.0 star property
Financial District, 2.5 km from UCSF Mission Bay
9.6 out of 10, Exceptional, (1004)
"I had a great stay. The room was nice, the bed was comfortable, and the staff were very helpful."
United States
Luke
The price is ₹10,591
₹16,171 total
includes taxes & fees
4 Jan - 5 Jan 2026
Galleria Park Hotel
Property entrance
Orchard Garden Hotel

Orchard Garden Hotel

4.0 star property
Chinatown, 2.7 km from UCSF Mission Bay
9.6 out of 10, Exceptional, (1004)
"Great location "
Canada
Jorge
The price is ₹12,066
₹14,402 total
includes taxes & fees
29 Dec - 30 Dec
Orchard Garden Hotel
Outdoor spa tub
Inn San Francisco

Inn San Francisco

2.5 star property
2.5 km from UCSF Mission Bay
9.6 out of 10, Exceptional, (577)
"Amazing breakfast and staff is super helpful."
United States
Stephanie
The price is ₹21,604
₹25,128 total
includes taxes & fees
8 Dec - 9 Dec
Inn San Francisco
Exterior
Hyatt Regency San Francisco Downtown SOMA

Hyatt Regency San Francisco Downtown SOMA

4.0 star property
South of Market, 2.2 km from UCSF Mission Bay
9.4 out of 10, Exceptional, (1302)
"Great stay"
United States
Eliran
The price is ₹14,149
₹20,242 total
includes taxes & fees
1 Jan - 2 Jan 2026
Hyatt Regency San Francisco Downtown SOMA
Room, 1 King Bed (High Floor) | City view
citizenM San Francisco Union Square

citizenM San Francisco Union Square

4.0 star property
Union Square, 2.3 km from UCSF Mission Bay
9.4 out of 10, Exceptional, (1417)
"Enjoyed our stay staff was friendly and helpful! Location was perfect!"
United States
Ana
The price is ₹9,629
₹11,333 total
includes taxes & fees
24 Dec - 25 Dec
citizenM San Francisco Union Square
Terrace/patio
Four Seasons Hotel San Francisco

Four Seasons Hotel San Francisco

5.0 star property
South of Market, 2.2 km from UCSF Mission Bay
9.4 out of 10, Exceptional, (1001)
"great room and staff. "
United States
chunguang
The price is ₹28,343
₹33,358 total
includes taxes & fees
3 Jan - 4 Jan 2026
Four Seasons Hotel San Francisco
Front of property – evening/night
Hotel Nikko San Francisco

Hotel Nikko San Francisco

4.5 star property
Union Square, 2.4 km from UCSF Mission Bay
9.4 out of 10, Exceptional, (2627)
"The entire hotel was fabulous!"
United States
Nicole
The price is ₹13,690
₹20,249 total
includes taxes & fees
17 Dec - 18 Dec
Hotel Nikko San Francisco
Suite, 1 Bedroom, Corner | Frette Italian sheets, premium bedding, down duvets, pillow-top beds
The St. Regis San Francisco

The St. Regis San Francisco

5.0 star property
South of Market, 2.1 km from UCSF Mission Bay
9.4 out of 10, Exceptional, (691)
"Had a great stay "
United Kingdom
Thomas
The price is ₹32,481
₹42,328 total
includes taxes & fees
23 Dec - 24 Dec
The St. Regis San Francisco
Exterior
Hyatt Place San Francisco Downtown

Hyatt Place San Francisco Downtown

3.0 star property
1.1 km from UCSF Mission Bay
9.2 out of 10, Wonderful, (1834)
"Great stay. "
United States
Jon
The price is ₹14,486
₹17,049 total
includes taxes & fees
3 Jan - 4 Jan 2026
Hyatt Place San Francisco Downtown
Sun deck
Hotel VIA

Hotel VIA

4.0 star property
1.2 km from UCSF Mission Bay
9.2 out of 10, Wonderful, (1491)
"Clean room, really friendly/ helpful staff, amazing views from the room."
United States
Breanni
The price is ₹15,308
₹18,016 total
includes taxes & fees
28 Dec - 29 Dec
Hotel VIA
Exterior
InterContinental San Francisco by IHG

InterContinental San Francisco by IHG

4.0 star property
South of Market, 1.8 km from UCSF Mission Bay
9.2 out of 10, Wonderful, (1017)
"Beautiful room and excellent food!"
United States
Melissa
The price is ₹13,949
₹20,125 total
includes taxes & fees
21 Dec - 22 Dec
InterContinental San Francisco by IHG
Lobby
The Clancy, Autograph Collection by Marriott

The Clancy, Autograph Collection by Marriott

4.0 star property
1.9 km from UCSF Mission Bay
9.2 out of 10, Wonderful, (1000)
"cleanliness,good service, convenient location"
United States
Harry
The price is ₹14,403
₹20,681 total
includes taxes & fees
23 Dec - 24 Dec
The Clancy, Autograph Collection by Marriott
View from property
Palace Hotel, a Luxury Collection Hotel, San Francisco

Palace Hotel, a Luxury Collection Hotel, San Francisco

5.0 star property
Financial District, 2.4 km from UCSF Mission Bay
9.2 out of 10, Wonderful, (1000)
"Everything was fantastic including the breakfast!"
United States
David
The price is ₹24,213
₹28,497 total
includes taxes & fees
3 Jan - 4 Jan 2026
Palace Hotel, a Luxury Collection Hotel, San Francisco
Room (Private Apartment) | Egyptian cotton sheets, premium bedding, minibar, in-room safe
The Clift Royal Sonesta San Francisco

The Clift Royal Sonesta San Francisco

4.0 star property
2.6 km from UCSF Mission Bay
9.2 out of 10, Wonderful, (1364)
"The hotel room was clean and above all else, the staff was incredible... We will only stay at this hotel when we come into town!"
United States
Jennie
The price is ₹13,406
₹19,288 total
includes taxes & fees
7 Dec - 8 Dec
The Clift Royal Sonesta San Francisco
Lobby
Beacon Grand, A Union Square Hotel

Beacon Grand, A Union Square Hotel

4.0 star property
Union Square, 2.6 km from UCSF Mission Bay
9.2 out of 10, Wonderful, (1808)
"Amazing place"
Australia
David
The price is ₹14,423
₹20,681 total
includes taxes & fees
18 Dec - 19 Dec
Beacon Grand, A Union Square Hotel
Premium bedding, pillow-top beds, in-room safe, desk
Inn At Union Square

Inn At Union Square

3.5 star property
2.6 km from UCSF Mission Bay
9.2 out of 10, Wonderful, (1005)
"Clean room, welcoming staff, we would stay again. "
United States
Natalie
The price is ₹9,313
₹13,209 total
includes taxes & fees
16 Dec - 17 Dec
Inn At Union Square
City view
Taj Campton Place

Taj Campton Place

5.0 star property
Union Square, 2.6 km from UCSF Mission Bay
9.2 out of 10, Wonderful, (1005)
"Wonderful Staff and hospitality."
United States
Rachel
The price is ₹16,016
₹21,957 total
includes taxes & fees
16 Dec - 17 Dec
Taj Campton Place
3 bars/lounges
Canopy by Hilton San Francisco SoMa

Canopy by Hilton San Francisco SoMa

4.0 star property
1.7 km from UCSF Mission Bay
9.0 out of 10, Wonderful, (1000)
"Good room , good service, good location "
United States
Albina
The price is ₹13,649
₹16,065 total
includes taxes & fees
26 Dec - 27 Dec
Canopy by Hilton San Francisco SoMa
Exterior
W San Francisco

W San Francisco

4.5 star property
2 km from UCSF Mission Bay
9.0 out of 10, Wonderful, (1005)
"Friendly staff, clean rooms, hotel near various venues."
United States
Eugene
The price is ₹13,586
₹19,170 total
includes taxes & fees
23 Dec - 24 Dec
W San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top UCSF Mission Bay Hotel Reviews

Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

10/10 Excellent
"Easily accessible and I liked having the bar/restaurant in the lobby"
Joanna 1-night trip
Posted 1 hour ago
Holiday Inn Golden Gateway by IHG

Hotels near other UCSF Mission Bay attractions

Chase Center San Francisco Skyline Aerial Photography

Chase Center

Catch an event at Chase Center during your trip to San Francisco. Amble around this vibrant area's Chinatown or experience its entertainment choices.
See properties
Anchor Brewing Company

Anchor Brewing Company

During your trip to San Francisco, you can do some window-shopping at Anchor Brewing Company. Discover the top-notch restaurants and acclaimed art galleries in this vibrant area.
See properties

Frequently asked questions

What's the area like around UCSF Mission Bay?
UCSF Mission Bay is located in a vibrant area of San Francisco known for its top museums and stunning architecture. If you're looking for a convenient place to stay, take a look at the 80 hotels and other accommodation options you'll find within a mile.
What's the best place to stay near UCSF Mission Bay?
LUMA Hotel San Francisco is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and a fitness centre. It's located just a short 0.4 mi (0.7 km) from UCSF Mission Bay. Other good choices within a short distance include Hyatt Place San Francisco Downtown and Hotel VIA.
How many hotels will I be able to find close to UCSF Mission Bay?
Expedia has 80 hotels and other accommodation options within a mile from UCSF Mission Bay.
If I need to cancel the hotel reservation for my stay near UCSF Mission Bay, will I receive a refund?
Yes! Most room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you have a reservation that's non-refundable, you might be able to cancel it and get a refund within a 24-hour period of your booking. Add dates, click "Search", then use the filter option "fully refundable" to view top deals close to UCSF Mission Bay.
What can I see and do near UCSF Mission Bay?
Study the collections at San Francisco Museum of Modern Art, Asian Art Museum of San Francisco or Market Street Railway Museum. Sights like San Francisco Mint, 450 Sutter Building and Ferry Building are landmarks to visit in the area. You can check out the local talent at Golden Gate Theatre, Warfield Theatre and Orpheum Theatre.
How can I get to UCSF Mission Bay?
With so many choices for transport, seeing all of the area near UCSF Mission Bay is simple. You can access metro transport at Market St & 5th St Stop, Market St & Taylor St Stop and Powell St & Market St Stop. If you're hopping a train into the city, San Francisco Station is the closest station to Downtown San Francisco.

Explore a world of travel with Expedia