TOP Business Hotels in South Naples, FL for 2026

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Our top choices for South Naples business-friendly hotels

Room, 1 King Bed, Accessible, Non Smoking (Mobility,Hearing Impaired) | Pillow-top beds, desk, iron/ironing board, free cots/infant beds

1. La Quinta Inn & Suites by Wyndham Naples East (I-75)

Naples

TONY

₹6,599

₹7,326 total

includes taxes & fees

9 Aug - 10 Aug

In-room safe, desk, blackout curtains, iron/ironing board

2. Holiday Inn Express Naples South I-75 by IHG

Rural Estates

Norelly

₹8,854

₹9,828 total

includes taxes & fees

7 Sept - 8 Sept

Suite, 1 Bedroom, Kitchen | Premium bedding, desk, laptop workspace, blackout curtains

3. Staybridge Suites Naples – Marco Island by IHG

Naples

Natalia

₹11,522

₹12,790 total

includes taxes & fees

26 Aug - 27 Aug

4. Fairfield Inn & Suites by Marriott Naples

Rural Estates

Katherine

₹8,570

₹9,513 total

includes taxes & fees

10 Aug - 11 Aug

Queen Room With 2 Queen Beds | Living area | TV

Family Double Room, 1 Double Bed, Non Smoking | Desk, iron/ironing board (on request), free WiFi, bed sheets

Queen Room With 2 Queen Beds | Desk, iron/ironing board (on request), free WiFi, bed sheets

5. Glades Motel

East Naples

thomas

₹5,010

₹6,312 total

includes taxes & fees

9 Aug - 10 Aug

Room, 2 Double Beds, Non Smoking | Pillow-top beds, desk, blackout curtains, iron/ironing board

6. La Quinta Inn & Suites by Wyndham Naples Downtown

East Naples

Lenar

₹6,356

₹7,056 total

includes taxes & fees

7 Sept - 8 Sept

Outdoor pool, pool umbrellas, pool loungers

7. Home2 Suites Naples I-75 Pine Ridge Road, FL

Naples

Manuel

₹8,511

₹9,448 total

includes taxes & fees

21 Aug - 22 Aug

Suite, Multiple Beds, Non Smoking, Kitchen (with Sofabed) | Hypo-allergenic bedding, in-room safe, desk, laptop workspace

8. Best Western Naples Plaza Hotel

Naples

Marcela

₹7,522

₹8,349 total

includes taxes & fees

9 Aug - 10 Aug

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Top South Naples Hotel Reviews

La Quinta Inn & Suites by Wyndham Naples East (I-75)

10/10 Excellent

"Si todo bien"

Conty's Motel

10/10 Excellent

"Great room for the price."

Holiday Inn Express Naples South I-75 by IHG

8/10 Good

"Hotel seemed smaller that normal Holiday Inn's (I.e. the lobby size, room size, breakfast area). Staff were polite, professional and helpful. The hotel was undergoing renovations at the time of our stay so that's probably why it didn't seem as clean."

Frequently asked questions

Why book your business-friendly hotel in South Naples with Expedia?

Here at Expedia, we make it our job to help you choose an ideal stay at the right price. From luxurious, corporate-friendly properties to affordable motor inns loaded with amenities, you'll have your next work trip organised in a few quick clicks.

How can I find cheap business-friendly hotels in South Naples?

Select the "business friendly" filter, listed just under the "traveller experience" heading, to find cheap business-friendly hotels in South Naples. Then refine your search by your per-night budget. Basing yourself in a less popular neighbourhood is another easy way to save.

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Check availability on South Naples Business Hotels

Our top choices for South Naples business-friendly hotels

1. La Quinta Inn & Suites by Wyndham Naples East (I-75)

2. Holiday Inn Express Naples South I-75 by IHG

3. Staybridge Suites Naples – Marco Island by IHG