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Our top choices for Panama luxury hotels

Reception
DoubleTree by Hilton Jamestown

DoubleTree by Hilton Jamestown

DoubleTree by Hilton Jamestown
4.0 star property
Jamestown
8.8 out of 10, Excellent, (919)
"Clean, comfortable, and nice staff."
United States
Julie
The price is ₹8,854
₹10,005 total
includes taxes & fees
2 Jan - 3 Jan 2026
DoubleTree by Hilton Jamestown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Panama Hotel Reviews

Holiday Inn Express Hotel & Suites in North East (Erie) by IHG

Holiday Inn Express Hotel & Suites in North East (Erie) by IHG

10/10 Excellent
"Clean and wonderful staff. Location was perfect and the place was quiet. "
Patricia 2-night trip
Posted 2 days ago
Holiday Inn Express Hotel & Suites in North East (Erie) by IHG

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Frequently asked questions

Are you looking for a luxury hotel for your stay in Panama?
Use Expedia to arrange your flight to Jamestown, NY (JHW-Chautauqua County) airport or Erie, PA (ERI-Erie Intl.) airport, and then choose from a variety of places to stay that will deliver the luxury you seek. Amenities are an important consideration when you plan a trip, so we make it easy to get what you'd like to make your stay special. If you want a posh hotel with fine dining, a spa or several swimming pools, Expedia can assist you in finding the best luxury hotel experience that Panama has to offer.
When can I expect good weather in Panama?
Planning for the weather is a good way to make your trip to Panama relaxing and enjoyable, especially when you're splurging. The hottest months are usually July and August, with an average temperature of 19°C, while the coldest months are January and February, with an average of -2°C. The snowiest months in Panama are January, November, March and December, with each month seeing an average of 21 cm of snowfall.
What's there to see and do in Panama?
When you're in Panama, enjoy exploring the sights and attractions here including Ashville Bay, Whitney Bay and Chautauqua Lake. If you have a little extra time during your trip, you might want to check out Long Point on Lake Chatauqua State Park and Chautauqua Institution.