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Check prices for these dates

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31 Jul - 2 Aug
Next weekend
7 Aug - 9 Aug

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Our top choices for Mayo Clinic Florida hotels

Breakfast, lunch and dinner served

1. Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic
4.5 star property
0.8 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (301 reviews)
"Great hotel and very convenient to Mayo."
United States
Margaret
The price is ₹16,313
₹18,516 total
includes taxes & fees
22 Aug - 23 Aug
Hilton Jacksonville At Mayo Clinic
Terrace/patio

2. Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
3.0 star property
0.4 km from Mayo Clinic Florida
8.4 out of 10, Very good, (790 reviews)
"Nice hotel for the money."
United States
Troy
The price is ₹14,538
₹16,501 total
includes taxes & fees
22 Aug - 23 Aug
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
Lobby

3. Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
1.1 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (566 reviews)
"I stayed at this hotel for 3 days. It was super clean and comfortable to stay the night for vacation."
United States
Devonta
The price is ₹13,076
₹14,841 total
includes taxes & fees
29 Aug - 30 Aug
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
Lobby

4. Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach
2.5 star property
5.9 km from Mayo Clinic Florida
8.8 out of 10, Excellent, (4,272 reviews)
"Excellent place to stay"
United States
stephen
The price is ₹16,089
₹18,261 total
includes taxes & fees
2 Aug - 3 Aug
Margaritaville Jacksonville Beach
Free daily buffet breakfast

5. Holiday Inn Express Jacksonville Beach by IHG

Holiday Inn Express Jacksonville Beach by IHG
3.0 star property
4.6 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,000 reviews)
"Great staff and location"
United States
Tiffany
The price is ₹10,534
₹11,956 total
includes taxes & fees
13 Aug - 14 Aug
Holiday Inn Express Jacksonville Beach by IHG
Exterior

6. Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
2.5 star property
4.2 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,197 reviews)
"Attentive and friendly staff, good location, generous breakfast"
Canada
Dagmar Maria
The price is ₹11,382
₹12,918 total
includes taxes & fees
30 Aug - 31 Aug
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
2 outdoor pools, open 7:00 AM to 9:00 PM, pool umbrellas, pool loungers

7. Hampton Inn Jacksonville Beach/Oceanfront

Hampton Inn Jacksonville Beach/Oceanfront
3.0 star property
6.3 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (2,644 reviews)
"Great place"
United States
Kevin
The price is ₹16,179
₹18,363 total
includes taxes & fees
17 Aug - 18 Aug
Hampton Inn Jacksonville Beach/Oceanfront
Terrace/patio

8. TownePlace Suites by Marriott Jacksonville East

TownePlace Suites by Marriott Jacksonville East
3.0 star property
Golden Glades - The Woods, 3.1 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (642 reviews)
"This is always a great place to stay especially because it’s close to the Mayo Clinic …a five minute drive"
United States
Miriam
The price is ₹11,886
₹13,491 total
includes taxes & fees
14 Aug - 15 Aug
TownePlace Suites by Marriott Jacksonville East
Lobby sitting area

9. Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
2.5 star property
2.6 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,021 reviews)
"Very helpful staff and nice view to the golf course."
United States
Jorge
The price is ₹9,462
₹10,740 total
includes taxes & fees
23 Aug - 24 Aug
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
Lobby

10. Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
2.5 star property
Golden Glades - The Woods, 3.1 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,000 reviews)
"Nice friendly hotel. Front desk so delightful, the breakfast staff goes above and beyond making sure everything is filled for breakfast ."
United States
Grace
The price is ₹10,926
₹12,401 total
includes taxes & fees
16 Aug - 17 Aug
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
Bar (on property)

11. Springhill Suites By Marriott Jacksonville Beach Oceanfront

Springhill Suites By Marriott Jacksonville Beach Oceanfront
4.0 star property
5.8 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (756 reviews)
"Great location, room was nice and we really enjoyed the pool and restaurant. Staff was helpful and can’t beat beachfront location."
United States
STEPHEN
The price is ₹17,805
₹20,208 total
includes taxes & fees
17 Aug - 18 Aug
Springhill Suites By Marriott Jacksonville Beach Oceanfront
On the beach

12. Best Western Oceanfront

Best Western Oceanfront
3.0 star property
5.7 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,002 reviews)
"Great place overall!!"
United States
Harkirat
The price is ₹13,466
₹15,284 total
includes taxes & fees
11 Aug - 12 Aug
Best Western Oceanfront
Point of interest

13. Dune House Hotel & Spa

Dune House Hotel & Spa
4.5 star property
8 km from Mayo Clinic Florida
8.8 out of 10, Excellent, (1,012 reviews)
"The Dune House is beautiful and the staff is so friendly! Will definitely be going back!"
United States
Jennifer
The price is ₹17,271
₹23,715 total
includes taxes & fees
9 Aug - 10 Aug
Dune House Hotel & Spa
Executive Suite, 1 Bedroom, Oceanfront | View from room

14. Courtyard by Marriott Jacksonville Beach Oceanfront

Courtyard by Marriott Jacksonville Beach Oceanfront
3.0 star property
6.4 km from Mayo Clinic Florida
8.6 out of 10, Excellent, (1,001 reviews)
"Beach was amazing! Love how close!"
United States
Vance
The price is ₹16,547
₹18,781 total
includes taxes & fees
30 Aug - 31 Aug
Courtyard by Marriott Jacksonville Beach Oceanfront
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to Mayo Clinic Florida

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Lobby
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
9.4
Exceptional
566 reviews
View
Breakfast, lunch and dinner served
Hilton Jacksonville At Mayo Clinic
4.5 star property
9.4
Exceptional
301 reviews
View
Terrace/patio
TownePlace Suites by Marriott Jacksonville East
3.0 star property
9.2
Wonderful
642 reviews
View
Lobby sitting area
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
2.5 star property
9.0
Wonderful
1,021 reviews
View
Lobby
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
2.5 star property
9.0
Wonderful
1,000 reviews
View

Top Mayo Clinic Florida Hotel Reviews

Best Western Oceanfront

Best Western Oceanfront

10/10 Excellent
"Great location! Beach view , clean and friendly"
Jasmine 4-night trip
Posted 8 hours ago
Best Western Oceanfront

Frequently asked questions

What's the area like around Mayo Clinic Florida?
Mayo Clinic Florida is located in a welcoming area of Jacksonville known for its beautiful beaches and surfing. If you're looking for a convenient place to stay, take a look at the 46 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay close to Mayo Clinic Florida?
Adjacent to Mayo Clinic Florida, Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an outdoor pool. Other good choices close by include Hilton Jacksonville At Mayo Clinic and Residence Inn By Marriott Jacksonville - Mayo Clinic Area.
How many hotels are there near Mayo Clinic Florida?
Expedia has 46 hotels and other accommodation options within a mile from Mayo Clinic Florida.
If I need to cancel the hotel reservation for my stay near Mayo Clinic Florida, will I receive a refund?
Yes! You'll find that most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to view the top deals on offer near Mayo Clinic Florida.
What can I see and do near Mayo Clinic Florida?
You can catch a show at Players by the Sea, SeaWalk Pavillion and SeaWalk Pavillion. Spend some time exploring the the natural beauty of Cradle Creek Preserve, Huguenot Park and Oceanfront Park. Lounge by the water at Northeast Florida Beaches and Ponte Vedra Beach.

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