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13 Mar - 14 Mar
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Our top choices for Mayo Clinic Florida hotels

Lobby lounge

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
1.1 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (470 reviews)
"Great stay! Clean room, friendly staff. "
United States
Sabrena
The price is ₹15,003
₹17,028 total
includes taxes & fees
21 Mar - 22 Mar
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
Breakfast, lunch, dinner served; American cuisine

Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic
4.5 star property
0.8 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (174 reviews)
"Great place to stay"
United States
Judy
The price is ₹15,045
₹17,076 total
includes taxes & fees
20 Mar - 21 Mar
Hilton Jacksonville At Mayo Clinic
Terrace/patio

TownePlace Suites by Marriott Jacksonville East

TownePlace Suites by Marriott Jacksonville East
3.0 star property
Golden Glades - The Woods, 3.1 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (587 reviews)
"Very nice accommodation , clean , and comfortable"
United States
Kevin
The price is ₹11,340
₹12,871 total
includes taxes & fees
29 Mar - 30 Mar
TownePlace Suites by Marriott Jacksonville East
Lobby

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
2.5 star property
Golden Glades - The Woods, 3.1 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,001 reviews)
"Nice room nice stay friendly staff"
United States
Thomas
The price is ₹10,131
₹11,498 total
includes taxes & fees
5 Apr - 6 Apr
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
Lobby sitting area

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
2.5 star property
2.6 km from Mayo Clinic Florida
8.8 out of 10, Excellent, (1,023 reviews)
"The staff was very friendly and knowledgeable and the morning breakfast was very good. Will be staying again in the future "
United States
Kimberly
The price is ₹10,326
₹11,720 total
includes taxes & fees
22 Mar - 23 Mar
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
Terrace/patio

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
3.0 star property
0.4 km from Mayo Clinic Florida
8.4 out of 10, Very good, (766 reviews)
"Room very clear; staff friendly and helpful; safe parking with accessibility to Mayo Clinic "
United States
Nancy
The price is ₹14,819
₹16,819 total
includes taxes & fees
21 Mar - 22 Mar
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
Exterior

Holiday Inn Express & Suites Jacksonville - Town Center by IHG

Holiday Inn Express & Suites Jacksonville - Town Center by IHG
2.5 star property
Southside, 7.7 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (1,000 reviews)
"Great location, friendly staff, nice rooms, great breakfast."
United States
Michelle
The price is ₹10,879
₹12,348 total
includes taxes & fees
2 Apr - 3 Apr
Holiday Inn Express & Suites Jacksonville - Town Center by IHG
Property amenity

Element Jacksonville Beach

Element Jacksonville Beach
3.0 star property
5.4 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (540 reviews)
"Great place (and location)!"
United States
Dale
The price is ₹14,844
₹16,847 total
includes taxes & fees
5 Apr - 6 Apr
Element Jacksonville Beach
Exterior

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
2.5 star property
4.2 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,041 reviews)
"Great staff and Clean hotel "
United States
Tyniesha
The price is ₹12,021
₹13,643 total
includes taxes & fees
22 Mar - 23 Mar
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
Standard Room, 1 King Bed, Non Smoking | Down duvets, minibar, iron/ironing board, WiFi

The Hotel Palms

The Hotel Palms
3.5 star property
7.8 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (294 reviews)
"stayed here for an event and it was awesome"
United States
clayton
The price is ₹17,396
₹19,745 total
includes taxes & fees
2 Apr - 3 Apr
The Hotel Palms
Property amenity

TownePlace Suites by Marriott® Jacksonville Mayport

TownePlace Suites by Marriott® Jacksonville Mayport
3.0 star property
10.8 km from Mayo Clinic Florida
9.8 out of 10, Exceptional, (86 reviews)
"Loved the staff, the cleanliness, and the food was excellent. Really enjoyed my stay here!!"
United States
Toni
The price is ₹11,525
₹13,080 total
includes taxes & fees
5 Apr - 6 Apr
TownePlace Suites by Marriott® Jacksonville Mayport
Lounge

AC Hotel Jacksonville St Johns Town Center

AC Hotel Jacksonville St Johns Town Center
2.5 star property
Southside, 8.1 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (181 reviews)
"Staff was excellent...highly recommend this Hotel"
Canada
Robert
The price is ₹17,425
₹19,778 total
includes taxes & fees
5 Apr - 6 Apr
AC Hotel Jacksonville St Johns Town Center
Lobby

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach
2.5 star property
5.9 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (3,732 reviews)
"Nice spot, friendly staff, nice bar and great beach location. "
United States
Keith
The price is ₹15,683
₹17,800 total
includes taxes & fees
5 Apr - 6 Apr
Margaritaville Jacksonville Beach
2 restaurants, breakfast served

The Lodge and Club at Ponte Vedra Beach

The Lodge and Club at Ponte Vedra Beach
5.0 star property
6.3 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (689 reviews)
"Clean room, excellent service and only steps from the ocean. The facility could use some TLC but, all in all, a wonderful place to stay. We’ll be back for sure. "
United States
Robert
The price is ₹46,006
₹53,970 total
includes taxes & fees
12 Apr - 13 Apr
The Lodge and Club at Ponte Vedra Beach
Sports facility

Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center
3.0 star property
Southside, 8.6 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,002 reviews)
"Everything was great"
United States
Antonio
The price is ₹10,510
₹11,929 total
includes taxes & fees
5 Apr - 6 Apr
Hyatt Place Jacksonville / St. Johns Town Center
Lobby

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
3.0 star property
8.5 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,013 reviews)
"Great stay all around "
United States
Jeffrey
The price is ₹14,364
₹16,016 total
includes taxes & fees
5 Apr - 6 Apr
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
Free daily buffet breakfast

Holiday Inn Express Jacksonville Beach by IHG

Holiday Inn Express Jacksonville Beach by IHG
3.0 star property
4.6 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,000 reviews)
"Overall a very convenient and clean facility."
United States
Chuck
The price is ₹12,078
₹13,708 total
includes taxes & fees
26 Mar - 27 Mar
Holiday Inn Express Jacksonville Beach by IHG
Property amenity

Sheraton Jacksonville Hotel

Sheraton Jacksonville Hotel
4.0 star property
Deerwood, 9.6 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,000 reviews)
"Beautiful property and great staff "
United States
Andrew
The price is ₹12,460
₹14,142 total
includes taxes & fees
27 Mar - 28 Mar
Sheraton Jacksonville Hotel
2 outdoor pools, open 7:00 AM to 9:00 PM, pool umbrellas, pool loungers

Hampton Inn Jacksonville Beach/Oceanfront

Hampton Inn Jacksonville Beach/Oceanfront
3.0 star property
6.3 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (2,639 reviews)
"Great place!"
United States
Kathleen
The price is ₹15,574
₹17,676 total
includes taxes & fees
13 Apr - 14 Apr
Hampton Inn Jacksonville Beach/Oceanfront
Bar (on property)

Springhill Suites By Marriott Jacksonville Beach Oceanfront

Springhill Suites By Marriott Jacksonville Beach Oceanfront
4.0 star property
5.8 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (648 reviews)
"Had an amazing getaway! "
United States
Meena
The price is ₹17,978
₹20,405 total
includes taxes & fees
22 Mar - 23 Mar
Springhill Suites By Marriott Jacksonville Beach Oceanfront
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mayo Clinic Florida Hotel Reviews

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

8/10 Good
"Pool is not heated, but facilities are clean and staff is great."
John 2-night trip
Posted 12 hours ago
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Hotels near other Mayo Clinic Florida attractions

Windsor Parke Golf Club

Enjoy a round of golf in Jacksonville at Windsor Parke Golf Club. Amble around the area's beautiful beaches or attend a sporting event.
See properties

Windsor Commons Shopping Center

You can find the perfect gifts to bring home at Windsor Commons Shopping Center during your trip to Jacksonville. Experience the area's acclaimed theatre scene and great live music.
See properties

Frequently asked questions

What's the area like around Mayo Clinic Florida?
Mayo Clinic Florida is located in a welcoming area of Jacksonville known for its beautiful beaches and surfing. If you're looking for a convenient place to stay, take a look at the 48 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay close to Mayo Clinic Florida?
Adjacent to Mayo Clinic Florida, Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an outdoor pool. Other good choices close by include Hilton Jacksonville At Mayo Clinic and Residence Inn By Marriott Jacksonville - Mayo Clinic Area.
How many hotels are there near Mayo Clinic Florida?
Expedia has 48 hotels and other accommodation options within a mile from Mayo Clinic Florida.
If I need to cancel the hotel reservation for my stay near Mayo Clinic Florida, will I receive a refund?
Yes! You'll find that most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to view the top deals on offer near Mayo Clinic Florida.
What can I see and do near Mayo Clinic Florida?
You can catch a show at SeaWalk Pavillion, Players by the Sea and SeaWalk Pavillion. Spend some time exploring the the natural beauty of Huguenot Park, Oceanfront Park and Cradle Creek Preserve. Lounge by the water at Northeast Florida Beaches and Ponte Vedra Beach.

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