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Check prices for these dates

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26 Jan - 27 Jan
Tomorrow
27 Jan - 28 Jan
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30 Jan - 1 Feb
Next weekend
6 Feb - 8 Feb

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Our top choices for Mayo Clinic Florida hotels

Breakfast, lunch, dinner served; American cuisine

Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic
4.5 star property
0.8 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (127 reviews)
"Great place to stay"
United States
Judy
The price is ₹16,514
₹18,743 total
includes taxes & fees
19 Feb - 20 Feb
Hilton Jacksonville At Mayo Clinic
Lobby

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
1.1 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (456 reviews)
"The staff was great at check in and the bar. Room was very clean, but the couch needed to be replaced."
United States
Wayne
The price is ₹16,093
₹18,265 total
includes taxes & fees
31 Jan - 1 Feb
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
Terrace/patio

TownePlace Suites by Marriott Jacksonville East

TownePlace Suites by Marriott Jacksonville East
3.0 star property
Golden Glades - The Woods, 3.1 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (568 reviews)
"Very good hotel"
United States
Careli
The price is ₹10,483
₹11,898 total
includes taxes & fees
5 Feb - 6 Feb
TownePlace Suites by Marriott Jacksonville East
Lobby

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
2.5 star property
Golden Glades - The Woods, 3.1 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,003 reviews)
"Clean and spacious room. Check-in staff very efficient and professional, great breakfast."
United States
Joe
The price is ₹10,481
₹11,896 total
includes taxes & fees
8 Feb - 9 Feb
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
Lobby sitting area

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
2.5 star property
2.6 km from Mayo Clinic Florida
8.6 out of 10, Excellent, (1,010 reviews)
"Great location - clean & quiet "
United States
Peter
The price is ₹10,483
₹11,898 total
includes taxes & fees
30 Jan - 31 Jan
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
Terrace/patio

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
3.0 star property
0.4 km from Mayo Clinic Florida
8.4 out of 10, Very good, (757 reviews)
"Great location "
United States
Josiah Christine
The price is ₹14,805
₹16,804 total
includes taxes & fees
7 Feb - 8 Feb
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
BBQ/picnic Area

Salt Air Inn & Suites

Salt Air Inn & Suites
2.5 star property
7.8 km from Mayo Clinic Florida
9.8 out of 10, Exceptional, (426 reviews)
"Amazing hotel absolute gem for Jacksonville beach "
United States
Justin
Salt Air Inn & Suites
Property amenity

Element Jacksonville Beach

Element Jacksonville Beach
3.0 star property
5.4 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (531 reviews)
"Great place (and location)!"
United States
Dale
The price is ₹12,414
₹14,090 total
includes taxes & fees
8 Feb - 9 Feb
Element Jacksonville Beach
Exterior

Holiday Inn Express & Suites Jacksonville - Town Center by IHG

Holiday Inn Express & Suites Jacksonville - Town Center by IHG
2.5 star property
Southside, 7.7 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (1,005 reviews)
"Location, cleanliness , property , staff was amazing"
United States
Justin
The price is ₹11,863
₹13,464 total
includes taxes & fees
5 Feb - 6 Feb
Holiday Inn Express & Suites Jacksonville - Town Center by IHG
Property amenity

TownePlace Suites by Marriott® Jacksonville Mayport

TownePlace Suites by Marriott® Jacksonville Mayport
3.0 star property
10.8 km from Mayo Clinic Florida
9.8 out of 10, Exceptional, (72 reviews)
"This was an awesome place to stay."
United States
Christine
The price is ₹11,495
₹13,046 total
includes taxes & fees
4 Feb - 5 Feb
TownePlace Suites by Marriott® Jacksonville Mayport
Standard Room, 2 Queen Beds, Non Smoking | Down duvets, minibar, iron/ironing board, WiFi

The Hotel Palms

The Hotel Palms
3.5 star property
7.8 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (293 reviews)
"stayed here for an event and it was awesome"
United States
clayton
The price is ₹15,541
₹17,639 total
includes taxes & fees
27 Jan - 28 Jan
The Hotel Palms
Exterior

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
2.5 star property
4.2 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,022 reviews)
"Clean room, good breakfast and location"
United States
Jesus
The price is ₹11,235
₹12,752 total
includes taxes & fees
4 Feb - 5 Feb
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
Couples treatment room(s), sauna, hot tub, steam room, body treatments

Ponte Vedra Inn & Club

Ponte Vedra Inn & Club
5.0 star property
6.3 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (815 reviews)
"Amazing. Loved it "
United States
Carol
The price is ₹45,593
₹53,503 total
includes taxes & fees
9 Feb - 10 Feb
Ponte Vedra Inn & Club
Beach/ocean view

The Lodge and Club at Ponte Vedra Beach

The Lodge and Club at Ponte Vedra Beach
5.0 star property
6.3 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (688 reviews)
"Clean room, excellent service and only steps from the ocean. The facility could use some TLC but, all in all, a wonderful place to stay. We’ll be back for sure. "
United States
Robert
The price is ₹45,887
₹53,831 total
includes taxes & fees
1 Feb - 2 Feb
The Lodge and Club at Ponte Vedra Beach
Lobby

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach
2.5 star property
5.9 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (3,560 reviews)
"Friendly staff, clean rooms and great atmosphere!"
United States
Susan
The price is ₹12,332
₹13,996 total
includes taxes & fees
27 Jan - 28 Jan
Margaritaville Jacksonville Beach
Lounge

AC Hotel Jacksonville St Johns Town Center

AC Hotel Jacksonville St Johns Town Center
2.5 star property
Southside, 8.1 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (176 reviews)
"Staff was excellent...highly recommend this Hotel"
Canada
Robert
The price is ₹18,300
₹20,770 total
includes taxes & fees
29 Jan - 30 Jan
AC Hotel Jacksonville St Johns Town Center
On the beach

Best Western Oceanfront

Best Western Oceanfront
3.0 star property
5.7 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,010 reviews)
"Great location, breakfast was delicious "
United States
Paul
The price is ₹11,328
₹12,858 total
includes taxes & fees
2 Feb - 3 Feb
Best Western Oceanfront
Bar (on property)

Springhill Suites By Marriott Jacksonville Beach Oceanfront

Springhill Suites By Marriott Jacksonville Beach Oceanfront
4.0 star property
5.8 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (631 reviews)
"The hotel was great! Very clean room and staff were very courteous and professional"
United States
Mike
The price is ₹16,368
₹18,578 total
includes taxes & fees
8 Feb - 9 Feb
Springhill Suites By Marriott Jacksonville Beach Oceanfront
Free daily buffet breakfast

Holiday Inn Express Jacksonville Beach by IHG

Holiday Inn Express Jacksonville Beach by IHG
3.0 star property
4.6 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,006 reviews)
"Great for the quick stay! "
United States
Aaron
The price is ₹10,575
₹12,003 total
includes taxes & fees
4 Feb - 5 Feb
Holiday Inn Express Jacksonville Beach by IHG
Outdoor pool, pool umbrellas, pool loungers

Four Points by Sheraton Jacksonville Beachfront

Four Points by Sheraton Jacksonville Beachfront
3.0 star property
5.6 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,002 reviews)
"Beds very comfortable. Check-in seamless. I loved my stay."
United States
Pizza
The price is ₹17,104
₹19,413 total
includes taxes & fees
22 Feb - 23 Feb
Four Points by Sheraton Jacksonville Beachfront
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mayo Clinic Florida Hotel Reviews

Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic

10/10 Excellent
"Spotless"
Herman 1-night trip
Posted 2 days ago
Hilton Jacksonville At Mayo Clinic

Hotels near other Mayo Clinic Florida attractions

Adventure Landing

4.1/5 (157 reviews)
This amusement park east of Jacksonville is a fun daytrip for the whole family with thrilling rides, exciting attractions for kids and a shipwreck-themed waterpark.
See properties

Windsor Parke Golf Club

Enjoy a round of golf in Jacksonville at Windsor Parke Golf Club. Amble around the area's beautiful beaches or attend a sporting event.
See properties

Frequently asked questions

What's the area like around Mayo Clinic Florida?
Mayo Clinic Florida is located in a welcoming area of Jacksonville known for its beautiful beaches and surfing. If you're looking for a convenient place to stay, take a look at the 46 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay close to Mayo Clinic Florida?
Adjacent to Mayo Clinic Florida, Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an outdoor pool. Other good choices close by include Hilton Jacksonville At Mayo Clinic and Residence Inn By Marriott Jacksonville - Mayo Clinic Area.
How many hotels are there near Mayo Clinic Florida?
Expedia has 46 hotels and other accommodation options within a mile from Mayo Clinic Florida.
If I need to cancel the hotel reservation for my stay near Mayo Clinic Florida, will I receive a refund?
Yes! You'll find that most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to view the top deals on offer near Mayo Clinic Florida.
What can I see and do near Mayo Clinic Florida?
You can enjoy live performances at Wilson Center For the Arts and Players by the Sea. Spend some time exploring the the natural beauty of Huguenot Park, Oceanfront Park and Cradle Creek Preserve. Lounge by the water at Northeast Florida Beaches and Ponte Vedra Beach.

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