TOP Gay-Friendly Hotels in Lake Nona Medical City, FL for 2026

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Our top choices for Lake Nona Medical City LGBT-friendly hotels

A swimming pool with sun loungers and palm trees.

1. Courtyard Orlando Lake Nona

Lake Nona

Yashira

₹17,241 total

includes taxes & fees

26 Nov - 27 Nov

A swimming pool with sun loungers and palm trees, surrounded by a modern building.

2. Residence Inn Orlando Lake Nona

Lake Nona

Christine

₹19,277 total

includes taxes & fees

24 Nov - 25 Nov

An outdoor patio area with tables and chairs, string lights, and palm trees.

3. Holiday Inn Express & Suites - Orlando - Southeast by IHG

Lake Hart

Bernice

₹11,769 total

includes taxes & fees

13 Dec - 14 Dec

A hotel with a prominent tower, palm trees, and a red roof.

4. La Quinta Inn & Suites by Wyndham Orlando Airport

Airport North

Reinaldo

₹5,359 total

includes taxes & fees

8 Dec - 9 Dec

A spacious lobby with a wooden staircase, a reception desk, and a large wall clock.

5. Country Inn & Suites by Radisson, Orlando Airport, FL

Airport North

Martin

₹8,021 total

includes taxes & fees

23 Nov - 24 Nov

An outdoor seating area with green chairs and umbrellas, a fire pit, and a building with large windows in the background.

6. Hampton Inn & Suites Orlando Airport @ Gateway Village

Airport North

William

₹11,176 total

includes taxes & fees

22 Nov - 23 Nov

A modern living room with a stone fireplace, a sofa, a coffee table, and a lamp.

7. Fairfield Inn By Marriott Orlando Airport

Airport North

Eddie

₹8,922 total

includes taxes & fees

14 Dec - 15 Dec

A modern hotel lobby with a large flat-screen TV, a blue sofa, a round wooden table, and a curved reception desk.

8. Cambria Hotel Orlando Airport

Orlando

SHAEA

₹10,094 total

includes taxes & fees

7 Dec - 8 Dec

9. Rosen Shingle Creek

Orlando

Dominic

₹10,743 total

includes taxes & fees

24 Nov - 25 Nov

A Hampton Inn hotel with a modern design, featuring a clear entrance, a flag, and a well-lit exterior.

10. Hampton Inn Kissimmee North

Kissimmee

Robert

₹11,730 total

includes taxes & fees

13 Dec - 14 Dec

View all properties

Compare popular hotels in Lake Nona Medical City

Property	Property class	Guest rating
Courtyard Orlando Lake Nona	3.0 star property	9.6 Exceptional 669 reviews	View
Residence Inn Orlando Lake Nona	3.0 star property	9.6 Exceptional 347 reviews	View
Holiday Inn Express & Suites - Orlando - Southeast by IHG	2.5 star property	9.2 Wonderful 1,042 reviews	View
La Quinta Inn & Suites by Wyndham Orlando Airport	3.0 star property	7.6 Good 3,008 reviews	View
Country Inn & Suites by Radisson, Orlando Airport, FL	3.0 star property	8.0 Very good 5,189 reviews	View

Top Lake Nona Medical City Hotel Reviews

Holiday Inn Express & Suites - Orlando - Southeast by IHG

Lake Hart

10/10 Excellent

Ben

Residence Inn Orlando Lake Nona

Lake Nona

10/10 Excellent

Anonymous traveller

Hampton Inn & Suites Orlando Airport @ Gateway Village

Airport North

10/10 Excellent

Mark

Fairfield Inn By Marriott Orlando Airport

Airport North

10/10 Excellent

Christopher

A Holiday Inn Express building with a modern design, featuring a prominent entrance and a covered walkway.

Holiday Inn Express Orlando International Airport by IHG

Orlando

10/10 Excellent

Lauren

A breakfast bar with various food items and a sign that reads "Happy Breakfast Starts Here."

Hampton Inn Orlando/Lake Buena Vista

Orlando

10/10 Excellent

Caroline

An outdoor seating area with a fire pit, sofas, and tables.

Home2 Suites by Hilton Orlando Airport

Airport North

10/10 Excellent

Lauryl

A hotel with a swimming pool surrounded by lounge chairs and palm trees.

Holiday Inn Express & Suites Orlando at SeaWorld by IHG

International Drive District

10/10 Excellent

Amanda

A hotel lobby with a reception desk, seating area, and a large mirror.

Hampton Inn & Suites Orlando-John Young Pkwy/S. Park

Orlando

10/10 Excellent

I broke up a long journey with a stay here as it was reasonably priced and close to the turnpike. The rooms are not super modern but they are very clean, huge and and they have a bath with I loved after a long day. The breakfast was free and started early which was good and the staff were really nice. Large comfortable bed and a quiet neighbourhood. If you’re in Orlando for business and aren’t looking for proximity to the parks as a priority, I can highly recommend this place.

jayne

An indoor swimming pool with clear blue water, surrounded by beige walls and a tiled floor.

Drury Inn & Suites near Universal Orlando Resort

Orlando

10/10 Excellent

Anonymous traveller

Frequently Asked Questions

Looking for a gay-friendly hotel in Lake Nona Medical City?

Consider this your open invitation to pack your bags and find Lake Nona Medical City hotels that are members of the International Gay & Lesbian Travel Association on our website. Visitors are sure to enjoy all Lake Nona Medical City has to offer including its restaurants.

What is the top LGBTQ-friendly place to stay in Lake Nona Medical City?

Courtyard Orlando Lake Nona is a top LGBTQ-friendly hotel that features free Wi-Fi and free parking. Residence Inn Orlando Lake Nona is another good option for your trip.

How many gay-friendly accommodation options are there in Lake Nona Medical City?

There are currently 2 gay-friendly hotels in Lake Nona Medical City.

What should I do while I'm visiting Lake Nona Medical City?

During your trip, get out and enjoy everything Lake Nona Medical City has to offer. You and your travelling companions may want to visit Universal Studios Florida, Walt Disney World® Resort and Universal Orlando Resort. While you're here, capture some great memories of your trip with stops at Disney Springs™, Orange County Convention Center and Epcot®.

What is a gay-friendly hotel in Lake Nona Medical City?

LGBTQ-friendly hotels are places where lesbian, gay, bisexual and transgender travellers are proudly welcomed. Expedia has worked with the International Gay and Lesbian Travel Association (IGLTA) to compile a selection of LGBTQ-friendly hotels worldwide. In Lake Nona Medical City, hotels affiliated with IGLTA operate in a spirit of inclusiveness, prioritising a diverse environment in which guests are welcomed, respected and not obliged to declare or hide their sexual orientation.

What can I expect from LGBTQ-friendly accommodation in Lake Nona Medical City?

Take a holiday from the ordinary; stay at an LGBTQ-friendly hotel in Lake Nona Medical City, and the staff will help you explore the local gay scene and the LGBTQ+ culture. Some of Expedia's LGBTQ-friendly hotels go the extra mile and offer wedding ceremonies and honeymoon packages for same-sex couples.

Search Gay-Friendly Hotels in Lake Nona Medical City

Change your mind

Treat yourself

Be picky

Check prices for these dates

Our top choices for Lake Nona Medical City LGBT-friendly hotels

1. Courtyard Orlando Lake Nona

2. Residence Inn Orlando Lake Nona

3. Holiday Inn Express & Suites - Orlando - Southeast by IHG

4. La Quinta Inn & Suites by Wyndham Orlando Airport

5. Country Inn & Suites by Radisson, Orlando Airport, FL

6. Hampton Inn & Suites Orlando Airport @ Gateway Village

7. Fairfield Inn By Marriott Orlando Airport

8. Cambria Hotel Orlando Airport

9. Rosen Shingle Creek

10. Hampton Inn Kissimmee North

Compare popular hotels in Lake Nona Medical City

Top Lake Nona Medical City Hotel Reviews

Holiday Inn Express & Suites - Orlando - Southeast by IHG

10/10 Excellent

Frequently Asked Questions

Looking for a gay-friendly hotel in Lake Nona Medical City?

What is the top LGBTQ-friendly place to stay in Lake Nona Medical City?

How many gay-friendly accommodation options are there in Lake Nona Medical City?

What should I do while I'm visiting Lake Nona Medical City?

What is a gay-friendly hotel in Lake Nona Medical City?

What can I expect from LGBTQ-friendly accommodation in Lake Nona Medical City?

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