Defiance Hotels from ₹5,840

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Our top choices for Defiance hotels

Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters
2.5 star property
St. Charles
8.0 out of 10, Very good, (1,006 reviews)
"Great location and friendly staff "
United States
Heather
The price is ₹8,596
₹9,879 total
includes taxes & fees
8 Feb - 9 Feb
Hampton Inn St. Charles St. Peters

Quality Inn Foristell

Quality Inn Foristell
2.5 star property
Foristell
8.2 out of 10, Very good, (923 reviews)
"Clean rooms, pleasant staff."
United States
Karen
The price is ₹6,776
₹7,653 total
includes taxes & fees
1 Feb - 2 Feb
Quality Inn Foristell

Comfort Inn & Suites St. Louis - O'Fallon

Comfort Inn & Suites St. Louis - O'Fallon
2.5 star property
O'Fallon
7.6 out of 10, Good, (1,003 reviews)
"Nice room, good front desk help"
United States
jeffrey
The price is ₹6,425
₹7,578 total
includes taxes & fees
20 Feb - 21 Feb
Comfort Inn & Suites St. Louis - O'Fallon

Sleep Inn & Suites O'Fallon MO - Technology Drive

Sleep Inn & Suites O'Fallon MO - Technology Drive
2.5 star property
O'Fallon
9.0 out of 10, Wonderful, (1,004 reviews)
"Very good place to stay"
United States
Jasur
The price is ₹7,251
₹8,552 total
includes taxes & fees
25 Jan - 26 Jan
Sleep Inn & Suites O'Fallon MO - Technology Drive

The Wildwood Hotel

The Wildwood Hotel
3.5 star property
Wildwood
9.2 out of 10, Wonderful, (1,626 reviews)
"Yes, the breakfast menu was very nice"
United States
Gregg
The price is ₹8,111
₹9,807 total
includes taxes & fees
27 Jan - 28 Jan
The Wildwood Hotel

Super 8 by Wyndham Warrenton

Super 8 by Wyndham Warrenton
2.0 star property
Warrenton
7.4 out of 10, Good, (625 reviews)
"Room was clean. Staff very helpful, accommodating. "
United States
Ranata
The price is ₹5,002
₹5,714 total
includes taxes & fees
18 Feb - 19 Feb
Super 8 by Wyndham Warrenton

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
3.0 star property
Fenton
8.0 out of 10, Very good, (1,085 reviews)
"Clean room, friendly staff and good breakfast"
United States
Elisabeth
The price is ₹7,816
₹9,028 total
includes taxes & fees
1 Feb - 2 Feb
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

WoodSpring Suites St Peters-OFallon

WoodSpring Suites St Peters-OFallon
2.5 star property
St. Peters
9.2 out of 10, Wonderful, (35 reviews)
"Super clean , quiet place "
United States
Phoenix
The price is ₹8,184
₹9,690 total
includes taxes & fees
25 Jan - 26 Jan
WoodSpring Suites St Peters-OFallon

Baymont by Wyndham Warrenton

Baymont by Wyndham Warrenton
2.5 star property
Warrenton
7.4 out of 10, Good, (1,001 reviews)
"Nice place and nice people "
United States
Columbus
The price is ₹6,773
₹7,736 total
includes taxes & fees
26 Jan - 27 Jan
Baymont by Wyndham Warrenton

Best Western Plus St. Louis West-Westport

Best Western Plus St. Louis West-Westport
2.5 star property
Maryland Heights
8.0 out of 10, Very good, (1,036 reviews)
"Excellent"
United States
Melanie
The price is ₹6,957
₹8,069 total
includes taxes & fees
1 Feb - 2 Feb
Best Western Plus St. Louis West-Westport

Holiday Inn Express & Suites Wentzville St Louis West by IHG

Holiday Inn Express & Suites Wentzville St Louis West by IHG
2.5 star property
Wentzville
9.4 out of 10, Exceptional, (864 reviews)
"Beautiful hotel, friendly staff, good breakfast."
United States
Erika
The price is ₹12,046
₹14,367 total
includes taxes & fees
31 Jan - 1 Feb
Holiday Inn Express & Suites Wentzville St Louis West by IHG

Drury Inn & Suites Southwest St. Louis

Drury Inn & Suites Southwest St. Louis
3.0 star property
Valley Park
9.6 out of 10, Exceptional, (1,006 reviews)
"Great stay"
United States
Maureen
Drury Inn & Suites Southwest St. Louis

Comfort Inn Near Six Flags St. Louis

Comfort Inn Near Six Flags St. Louis
2.5 star property
Pacific
8.4 out of 10, Very good, (887 reviews)
"The room was impeccable and the front desk and custodial staff incredibly hospitable."
United States
Scott
The price is ₹8,379
₹9,592 total
includes taxes & fees
9 Feb - 10 Feb
Comfort Inn Near Six Flags St. Louis

Best Western Plus The Charles Hotel

Best Western Plus The Charles Hotel
3.0 star property
St. Charles
8.2 out of 10, Very good, (1,006 reviews)
"Very nice at service desk, room clean and comfortable, breakfast really good. Would recommend, would stay again!"
United States
Melisa
The price is ₹7,738
₹8,971 total
includes taxes & fees
29 Jan - 30 Jan
Best Western Plus The Charles Hotel

Wingate by Wyndham St. Louis/Fenton Route 66

Wingate by Wyndham St. Louis/Fenton Route 66
3.0 star property
Fenton
7.8 out of 10, Good, (1,139 reviews)
"Clean rooms, quiet, AC worked great and good breakfast "
United States
Karen
The price is ₹7,243
₹8,365 total
includes taxes & fees
10 Feb - 11 Feb
Wingate by Wyndham St. Louis/Fenton Route 66

Super 8 by Wyndham Washington

Super 8 by Wyndham Washington
2.0 star property
Washington
8.4 out of 10, Very good, (705 reviews)
"The staff was extremely nice & accommodating."
United States
Brenda
The price is ₹7,747
₹8,820 total
includes taxes & fees
1 Feb - 2 Feb
Super 8 by Wyndham Washington

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
3.0 star property
Maryland Heights
7.6 out of 10, Good, (1,003 reviews)
"The room was clean and spacious and the staff was really nice."
United States
D
The price is ₹5,899
₹6,843 total
includes taxes & fees
1 Feb - 2 Feb
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Drury Plaza Hotel St. Louis Chesterfield

Drury Plaza Hotel St. Louis Chesterfield
3.0 star property
Chesterfield
9.6 out of 10, Exceptional, (1,055 reviews)
"The staff was super nice. "
United States
Timothy
The price is ₹11,910
₹13,814 total
includes taxes & fees
1 Feb - 2 Feb
Drury Plaza Hotel St. Louis Chesterfield

Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis
2.5 star property
St. Charles
8.4 out of 10, Very good, (1,008 reviews)
"Great hotel for the money"
United States
Jere
The price is ₹6,915
₹7,947 total
includes taxes & fees
1 Feb - 2 Feb
Comfort Suites St Charles - St Louis

Hilton Garden Inn St. Louis/O'Fallon MO

Hilton Garden Inn St. Louis/O'Fallon MO
3.0 star property
O'Fallon
8.8 out of 10, Excellent, (723 reviews)
"Easy check in, decent stay. Not quite the cleanest, there were hairs in the bathroom "
United States
Devin
The price is ₹8,780
₹10,411 total
includes taxes & fees
8 Feb - 9 Feb
Hilton Garden Inn St. Louis/O'Fallon MO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Defiance attractions

Learn more about Defiance

Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighbouring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

A covered bridge at the Historic Daniel Boone Home Park in Defiance, Missouri

Top Defiance Hotel Reviews

More cheap stays in Defiance

Frequently asked questions

What's the best place to stay in Defiance?
Ameristar Casino Resort and Spa, located 18.3 mi (29.5 km) from the heart of Defiance, is a top choice for your stay, based on our traveller data. Two other options for your visit to the area are The Wildwood Hotel and La Quinta Inn & Suites by Wyndham St. Louis Westport. See all available top hotels, or vacation rentals in Defiance.
If I need to cancel my hotel reservation in Defiance, will I receive a refund?
Yes! The majority of room reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Defiance.
What are some accommodation options with pools in Defiance?
Ameristar Casino Resort and Spa: Hotel steps from Ameristar Casino St. Charles. Features 6 restaurants, a seasonal outdoor pool and a full-service spa. The Wildwood Hotel and La Quinta Inn & Suites by Wyndham St. Louis Westport are two additional hotels with an on-site pool. View all hotels with pools in Defiance.
How is it staying in Defiance?
Visitors can enjoy all that Defiance has to offer, including the wineries and parks. Top sights in the area include St. Louis Union Station, Busch Stadium and Gateway Arch. In Defiance, there are 19 hotels and other accommodation options to choose from. Find out more about Defiance.
What should I do while I'm visiting Defiance?
Natural beauty is on display at Matson Hill Park Trailhead, August A. Busch Memorial Conservation Area and Missouri River. A couple of additional sights to add to your itinerary are Yellow Farmhouse Winery and Chandler Hill Vineyards. Take a look at what more there is to see and do in Expedia's Defiance guide.
What's the weather like in Defiance?
The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Defiance is 1228 mm.

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