𝗧𝗢𝗣 𝟭𝟬 𝗛𝗼𝘁𝗲𝗹𝘀 𝗶𝗻 Defiance (2026)

A rustic covered bridge with a wooden structure and red accents, surrounded by lush greenery and trees.

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Go beyond your typical stay in Defiance

Waterpark

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Hot tub

Pet friendly

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Our top choices for Defiance hotels

A hotel room with two beds, a desk with a chair, a television, and a window with curtains.

An indoor swimming pool with clear water, marked depth lines, and a lifeguard chair.

A hotel lobby with a seating area, a reception desk, and a flat-screen TV mounted on the wall.

A bathroom with a granite countertop sink, a mirror, a toilet, and two framed artworks on the wall.

1. Holiday Inn Express St. Louis West - O'Fallon by IHG

O'Fallon

David

₹9,637

₹11,366 total

includes taxes & fees

31 Aug - 1 Sept

A hotel room with a bed, a sofa, a coffee table, and wall art.

A hotel lobby with a reception desk, seating area, and a large potted plant.

An indoor swimming pool with a clear view of the outside, a metal ladder, and a ceiling with recessed lighting.

A Sleep Inn & Suites hotel with a modern brick facade, a covered entrance, and a parking lot.

2. Sleep Inn & Suites O'Fallon MO - Technology Drive

O'Fallon

Josh

₹8,248

₹9,729 total

includes taxes & fees

31 Aug - 1 Sept

A hotel with a prominent tower, a fountain in the courtyard, and a well-maintained garden.

A hotel room with a large bed, a bedside lamp, a telephone, a mirror, and a bathroom with a sink and towel rack.

A formal dining table set for six with a vase of white flowers, candles, and a view of buildings through large windows.

A modern bathroom with a large mirror, white vanity, and a bathtub.

3. The Wildwood Hotel

Wildwood

Hailey

₹7,574

₹8,823 total

includes taxes & fees

31 Aug - 1 Sept

A modern kitchen with a bar area, wooden cabinets, and pendant lighting.

A hotel room with two beds, a sofa, a small table, a lamp, and a framed abstract painting on the wall.

A hotel room with three computer workstations, each with a monitor, keyboard, and a lamp.

A swimming pool with a tiled deck, a sunlit room with a view, and a seating area with chairs.

4. Hyatt Place St. Louis/Chesterfield

Chesterfield

Taylor

₹11,154

₹12,937 total

includes taxes & fees

13 Sept - 14 Sept

An outdoor patio area with a stone fire pit, wicker furniture, and a covered seating area with a view of the building's interior.

A multi-story hotel with a brick facade, a covered outdoor seating area with a fire feature, and a sign indicating it is a Marriott property.

A modern kitchen with wooden cabinets, a stainless steel countertop, and various appliances including a coffee maker and a rice cooker.

A hotel room with a large bed, bedside lamps, a TV, a desk, and a bathroom.

5. TownePlace Suites by Marriott St. Louis Chesterfield

Chesterfield

Bobbi jo

₹12,213

₹14,333 total

includes taxes & fees

6 Sept - 7 Sept

A hotel room with two beds, a desk, a chair, a TV, and a large window.

A brick building with a sign reading "Comfort Inn & Suites."

A modern dining area with a brick fireplace, yellow and blue chairs, and a blue sofa.

A spacious lobby with a blue sofa set, a reception desk, and a modern chandelier.

6. Comfort Inn & Suites Chesterfield - St. Louis

Chesterfield

Joe

₹8,596

₹10,336 total

includes taxes & fees

30 Aug - 31 Aug

A spacious lobby with a high ceiling, a central seating area with sofas and a coffee table, and a large window providing natural light.

A shop with a variety of snacks and beverages, including a refrigerated section with drinks and a display of packaged snacks.

A hotel with a covered entrance, multiple flags, and a well-maintained lawn.

A spacious lobby with a fireplace, comfortable seating, a large painting, and a view of the kitchen area.

7. Hilton Garden Inn St. Louis/O'Fallon MO

O'Fallon

Kassie

₹11,658

₹13,823 total

includes taxes & fees

3 Sept - 4 Sept

A courtyard with a central seating area, surrounded by trees and a building with a pitched roof.

A modern hotel room with a large window, a desk with a flat-screen TV, a comfortable seating area, and a decorative wall piece.

A reception desk with a "WELCOME TO THE SHOW ME STATE" sign, a wooden counter, and a Hilton Honors sign.

A store interior with a 'Treats' sign, snack shelves, and a chalkboard with a welcome message.

8. Hampton Inn & Suites St. Louis/Chesterfield

Chesterfield

Karen E

₹10,484

₹12,199 total

includes taxes & fees

13 Sept - 14 Sept

An outdoor patio with a built-in grill, seating area, and stone walls.

A multi-story hotel with a parking lot in front.

An indoor swimming pool with clear glass walls, sunlit seating area, and lifeguard station.

A spacious lounge area with a stone fireplace, comfortable seating, and a large TV screen.

9. Residence Inn by Marriott St. Louis Chesterfield

Chesterfield

Tenisha

₹18,033

₹21,096 total

includes taxes & fees

3 Sept - 4 Sept

A spacious lobby with a high ceiling, a dining area, and a kitchen in the background.

A modern hotel lobby with a computer desk, a flat-screen TV, and a ceiling fan.

A hotel room with a bathroom, a bed, a nightstand, and a window.

A lobby with a checkered carpet, a marble coffee table, two armchairs with patterned cushions, a sofa, and a dining table with chairs.

10. Quality Inn Near Six Flags St. Louis

Pacific

Diane

₹9,880

₹11,310 total

includes taxes & fees

30 Aug - 31 Aug

A modern kitchen area with a breakfast bar, a coffee machine, and a refrigerator displaying menu options.

A hotel reception area with two reception desks, a modern wall design, and a person standing behind one of the desks.

An indoor swimming pool with clear lane markings, a pool lift, and a capacity sign indicating 47 users.

A modern hotel lobby with a seating area, a map mural, and a television.

11. Holiday Inn Express & Suites St. Louis - Chesterfield by IHG

Chesterfield

NEBAHAT

₹10,867

₹12,646 total

includes taxes & fees

30 Aug - 31 Aug

A spacious lobby with a central round table, two sofas, and a chandelier.

A buffet setup with various food items and a decorative vase of flowers.

A Drury Plaza hotel with a modern design, featuring a curved facade, large windows, and a Drury Plaza sign on the top.

An indoor swimming pool area with clear signage indicating a depth of 3 feet and a no diving warning.

12. Drury Plaza Hotel St. Louis Chesterfield

Chesterfield

Andrea T

₹12,403

₹14,386 total

includes taxes & fees

1 Sept - 2 Sept

A hotel reception area with a counter, coffee machines, a refrigerated display, and artwork on the wall.

A reception desk with a wooden finish, a clock, and a sign for Marriott Bonvoy.

A hotel room with a bed, desk, TV, and a view of the outdoors.

A snack bar with shelves of chips, candies, and bottled water.

13. Fairfield Inn & Suites by Marriott St. Louis Chesterfield

Chesterfield

Carl

₹10,219

₹11,852 total

includes taxes & fees

7 Sept - 8 Sept

A hotel lobby with a sectional sofa, a fireplace, a flat-screen TV, and framed artwork on the walls.

A multi-story hotel with a central entrance featuring a covered patio area.

A Staybridge Suites hotel sign with a modern building in the background.

A swimming pool with clear blue water, surrounded by a patio area with outdoor seating and a building with multiple windows in the background.

14. Staybridge Suites O'Fallon Chesterfield by IHG

O'Fallon

Norman

₹10,591

₹12,492 total

includes taxes & fees

31 Aug - 1 Sept

A hotel named Sonesta ES Suites with a staircase leading to the entrance, surrounded by well-maintained greenery and red flowers.

A 'check in' sign in front of a building with a landscaped garden and a lamp post.

A compact kitchen with a refrigerator, microwave, stove, and a small dining table with two stools.

A hotel room with a living area, kitchenette, and a bedroom visible through a door.

15. Sonesta ES Suites St. Louis - Chesterfield

Chesterfield

Ernest L

₹9,489

₹11,005 total

includes taxes & fees

30 Aug - 31 Aug

An outdoor patio area with wicker furniture and a central fire feature.

A modern hotel lobby with a reception desk, seating area, and a television screen displaying a map.

A modern hotel lobby with a bar area, seating arrangements, and a reception desk.

A Courtyard Marriott hotel with a parking lot and a green shuttle service.

16. Courtyard by Marriott St. Louis Chesterfield

Chesterfield

Kelly

₹11,936

₹13,889 total

includes taxes & fees

13 Sept - 14 Sept

A spacious living room with a large painting, a fireplace, a staircase, and modern furniture.

An outdoor patio with a beige sofa set, two armchairs, and a table.

A hotel room with a large bed, two sofas, a desk, and a TV.

A swimming pool with tiled edges and a hot tub area, surrounded by windows and chairs.

17. Best Western Plus Washington Hotel

Washington

Michael Macumber

₹12,308

₹14,013 total

includes taxes & fees

30 Aug - 31 Aug

A spacious lobby with a high ceiling, a dining area, and a seating area with sofas and a coffee table.

A hotel room with a bed, a dresser, a nightstand with a lamp, a framed map on the wall, and a carpeted floor.

A spacious lobby with a blue sofa, round coffee table, and blue chairs. There is a reception desk and a seating area with a high ceiling and large windows.

An outdoor patio area with a table and chairs, a glass door entrance, and a visible interior with a dining area.

18. Drury Inn & Suites St. Louis St. Peters

St. Peters

Melanie

₹10,494

₹12,063 total

includes taxes & fees

6 Sept - 7 Sept

A spacious lobby with a stone fireplace, seating area, and a bar with high stools.

A modern living room with a fireplace, a flat-screen TV, a sofa, a coffee table, and a dining area.

A hotel pantry stocked with beverages and snacks, a refrigerated display case, and a sign reading "The Market".

A multi-story hotel with a central entrance, large windows, and a well-maintained lawn.

19. Residence Inn by Marriott O'Fallon

O'Fallon

Gerald

₹12,499

₹14,743 total

includes taxes & fees

13 Sept - 14 Sept

A spacious lobby with a staircase, a blue sofa, and a wooden table.

A gym with treadmills, weight machines, and a large potted plant.

A hotel reception desk with a blue water feature design, a sign reading "Quality by Choice Hotels," and a digital screen.

A modern interior with a large window, a flat-screen TV mounted on a wall, and a seating area with colorful stools.

20. Quality Inn Foristell

Foristell

Rebecca

₹7,814

₹8,827 total

includes taxes & fees

31 Aug - 1 Sept

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Stay near popular Defiance attractions

A wooden dock extending into a pond with lily pads, surrounded by lush greenery and a clear blue sky.

August A. Busch Memorial Conservation Area

8.6/10 (7 reviews)

This sprawling conservation area features over 30 lakes and historic WWII bunkers amid diverse habitats. Explore well-maintained trails while watching for migratory birds and wildlife in their natural environment.

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A glass of red wine on a wooden table with a vineyard in the background.

Chandler Hill Vineyards

7.8/10 (7 reviews)

This elegant Missouri winery showcases local and California wines from its hillside setting. Savour varietals on the expansive terrace while enjoying vineyard views and seasonal cuisine from their full-service kitchen.

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Historic Daniel Boone Home and Heritage Center

9.6/10 (4 reviews)

Step into the limestone home where Daniel Boone's son Nathan crafted a frontier masterpiece with seven fireplaces. Explore the surrounding historic village for an authentic glimpse into 19th-century pioneer life.

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Sugar Creek Winery

8.0/10 (1 review)

Sip award-winning Missouri wines at this hillside vineyard along the scenic Katy Trail. Relax on covered decks with your own picnic while enjoying live weekend music and panoramic countryside views.

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Yellow Farmhouse Winery

This boutique winery in Defiance, Missouri was known for its distinctive unfiltered wines and relaxed atmosphere. Visitors could enjoy tastings with live music while picnicking on scenic grounds with vineyard views.

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Matson Hill Park Trailhead

Wander through 475 acres of rugged forest terrain with challenging hiking paths and gravity-flow mountain bike trails. The historic 1830s Hays Home offers a glimpse into pioneer life amid the natural splendour.

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Broemmelsiek Park

This 494-acre natural playground offers nine miles of trails through forests and around serene lakes. Attend a monthly stargazing event at the astronomy viewing area for a uniquely celestial park experience.

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Hamburg Trail Trailhead

This moderate 6.9-mile loop winds through the scenic Weldon Spring Conservation Area, connecting to the Katy Trail State Park. Spot native wildlife while traversing diverse landscapes of shaded woodlands and open fields.

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Learn more about Defiance

Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighbouring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

See all hotels in Defiance

Top Defiance Hotel Reviews

Best Western Plus St. Louis West-Westport

10/10 Excellent

"Friendly staff, clean rooms, great location."

The Wildwood Hotel

10/10 Excellent

"Absolutely BEAUTIFUL!! Small town, quiet, extremely friendly! Would recommend to everyone staying in the area!!"

Drury Inn & Suites Southwest St. Louis

10/10 Excellent

"This is always my first choice when staying in the High Ridge Vally Park Missouri area. They have the best staff. Excellent Rooms always very clean"

Hilton St. Louis Frontenac

10/10 Excellent

"The staff was very helpful"

Hampton Inn St. Charles St. Peters

10/10 Excellent

"We checked in a little early because we were there to attend a funeral, and the staff was able to accommodate us"

Holiday Inn St. Louis West Six Flags by IHG

8/10 Good

"Our room was not clean when we arrived. There were whiskers in and around the sink, and dead bugs in the shower."

Courtyard by Marriott St Louis Westport Plaza

10/10 Excellent

"Absolutely loved this place. Comfy beds. Spacious suites"

More cheap stays in Defiance

Days Inn and Suites by Wyndham St. Louis/Westport Plaza

1970 Craig Rd Maryland Heights MO

₹6,488

₹7,525 total

30 Aug - 31 Aug

includes taxes & fees

4.6/10 (1,002 reviews)

Sleep Inn & Suites O'Fallon MO - Technology Drive

1147 Technology Drive O'Fallon MO

₹8,248

₹9,729 total

31 Aug - 1 Sept

includes taxes & fees

Best Western Plus St. Louis West-Westport

12220 Dorsett Rd Maryland Heights MO

₹8,434

₹9,783 total

6 Sept - 7 Sept

includes taxes & fees

8/10 Very good! (1,095 reviews)

Hampton Inn St. Charles St. Peters

3720 W Clay St St. Charles MO

₹9,310

₹10,700 total

3 Sept - 4 Sept

includes taxes & fees

8/10 Very good! (1,000 reviews)

Best Western Plus Fenton

1680 Fenton Business Park Ct Fenton MO

₹9,463

₹10,929 total

30 Aug - 31 Aug

includes taxes & fees

Holiday Inn Express & Suites St. Louis - Chesterfield by IHG

11 Arnage Boulevard Chesterfield MO

₹10,867

₹12,646 total

30 Aug - 31 Aug

includes taxes & fees

9/10 Wonderful! (1,001 reviews)

Frequently asked questions

What's the best place to stay in Defiance?

Hollywood Casino & Hotel St. Louis, located 18.1 mi (29.2 km) from the heart of Defiance, is a top choice for your stay, based on our traveller data. Two other options for your visit to the area are Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham and Ameristar Casino Resort and Spa. See all available top hotels, or vacation rentals in Defiance.

If I need to cancel my hotel reservation in Defiance, will I receive a refund?

Yes! The majority of room reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Defiance.

What are some accommodation options with pools in Defiance?

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham: Offers an indoor pool, an outdoor pool and buffet. Ameristar Casino Resort and Spa and The Wildwood Hotel are two additional hotels with an on-site pool. View all hotels with pools in Defiance.

How is it staying in Defiance?

Visitors can enjoy all that Defiance has to offer, including the wineries and parks. Top sights in the area include St. Louis Union Station, Busch Stadium and Gateway Arch. In Defiance, there are 19 hotels and other accommodation options to choose from. Find out more about Defiance.

What should I do while I'm visiting Defiance?

Natural beauty is on display at August A. Busch Memorial Conservation Area, Missouri River and Matson Hill Park Trailhead. A couple of additional sights to add to your itinerary are Yellow Farmhouse Winery and Chandler Hill Vineyards. Take a look at what more there is to see and do in Expedia's Defiance guide.

What's the weather like in Defiance?

The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Defiance is 1228 mm.

Explore a world of travel with Expedia

Book Hotels in Defiance on Expedia.com

Defiance Hotels from ₹7,463

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Defiance

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Defiance hotels

1. Holiday Inn Express St. Louis West - O'Fallon by IHG

2. Sleep Inn & Suites O'Fallon MO - Technology Drive

3. The Wildwood Hotel

4. Hyatt Place St. Louis/Chesterfield

5. TownePlace Suites by Marriott St. Louis Chesterfield

6. Comfort Inn & Suites Chesterfield - St. Louis

7. Hilton Garden Inn St. Louis/O'Fallon MO

8. Hampton Inn & Suites St. Louis/Chesterfield

9. Residence Inn by Marriott St. Louis Chesterfield

10. Quality Inn Near Six Flags St. Louis

11. Holiday Inn Express & Suites St. Louis - Chesterfield by IHG

12. Drury Plaza Hotel St. Louis Chesterfield

13. Fairfield Inn & Suites by Marriott St. Louis Chesterfield

14. Staybridge Suites O'Fallon Chesterfield by IHG

15. Sonesta ES Suites St. Louis - Chesterfield

16. Courtyard by Marriott St. Louis Chesterfield

17. Best Western Plus Washington Hotel

18. Drury Inn & Suites St. Louis St. Peters

19. Residence Inn by Marriott O'Fallon

20. Quality Inn Foristell

Stay near popular Defiance attractions

August A. Busch Memorial Conservation Area

Chandler Hill Vineyards

Historic Daniel Boone Home and Heritage Center

Sugar Creek Winery

Yellow Farmhouse Winery

Matson Hill Park Trailhead

Broemmelsiek Park

Hamburg Trail Trailhead

Learn more about Defiance

Top Defiance Hotel Reviews

Best Western Plus St. Louis West-Westport

The Wildwood Hotel

Drury Inn & Suites Southwest St. Louis

Hilton St. Louis Frontenac

Hampton Inn St. Charles St. Peters

Holiday Inn St. Louis West Six Flags by IHG

Courtyard by Marriott St Louis Westport Plaza

More cheap stays in Defiance

Days Inn and Suites by Wyndham St. Louis/Westport Plaza

Sleep Inn & Suites O'Fallon MO - Technology Drive

Best Western Plus St. Louis West-Westport

Hampton Inn St. Charles St. Peters

Best Western Plus Fenton

Holiday Inn Express & Suites St. Louis - Chesterfield by IHG

Frequently asked questions

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