Cheap Flights from Des Moines (DSM) to Charleston (CHS)

Start packing your suitcase, because round-trip flights from Des Moines Intl. Airport (DSM) to CHS start from . That’s based on airfares available within the last 7 days on Expedia for flights departing within the next year. Prices can change quickly, so book today to get the best deal. Prices and availability are subject to change. Additional terms apply.

Most flights can be cancelled online, but every air carrier has its own set of terms and conditions. If you do need to cancel your flight, go to our Customer Service Portal and follow the instructions.

Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you’re searching for DSM to CHS flights, you’ll see a “no change fees” filter for you to select.

It’s around 1,550 kilometres from Des Moines to North Charleston, so expect to be flying for a while. Keep yourself occupied with things like your e-reader or a gripping book.

At present, no airlines offer direct flights from DSM to CHS. You’ll need to book a flight with one or more stops. To score the best connections and price, lock in your airfare well in advance.

Booking last minute from Des Moines Intl. Airport (DSM) to Charleston Intl. Airport can be hit-or-miss. You may be able to score a great bargain, but then again, you could miss out entirely! If you’d prefer to start planning early on, Expedia compares flight deals up to a year in advance. Just remember that not all airlines release their prices that far in advance. Our advice? Check back often as prices are updated regularly.