Downtown South San Francisco Travel Guide

San Francisco

Aerial View of a Local High School and an Athletic Field in a Neighborhood in South San Francisco, California, USA
Aerial view of the South San Francisco area
Aerial view of downtown San Francisco and Financial District sky scrapers flying over South San Francisco The Industrial City inscription on San Bruno mountain circa 2015

Popular places to visit


Top hotels in Downtown South San Francisco

La Quinta Inn & Suites by Wyndham San Francisco Airport N

La Quinta Inn & Suites by Wyndham San Francisco Airport N

3 out of 5
20 Airport Blvd South San Francisco CA
The price is ₹9,161 per night from 31 May to 1 Jun
₹9,161
₹10,771 total
31 May - 1 Jun
includes taxes & fees
Stay at this business-friendly hotel in South San Francisco. Enjoy free breakfast, free Wi-Fi and a free airport shuttle. Our guests praise the breakfast and ...
8.2/10 Very Good! (1,972 reviews)
Very clean and wonderful staff

Reviewed on 6 May 2026

La Quinta Inn & Suites by Wyndham San Francisco Airport N
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
The price is ₹13,667 per night from 25 May to 26 May
₹13,667
₹19,969 total
25 May - 26 May
includes taxes & fees
Stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the ...
9/10 Wonderful! (7,469 reviews)
Overall the hotel was great. The staff are amazing and helpful. The breakfast is a buffet and has a variety of options. Pool is nice as well but too cold during this time. The rooms were clean tidy and decently spacious. Only issue is the wifi isn’t the greatest and at times slow.

Reviewed on 8 May 2026

Hotel Riu Plaza Fisherman's Wharf
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
The price is ₹12,417 per night from 25 May to 26 May
₹12,417
₹14,615 total
25 May - 26 May
includes taxes & fees
Stay at this business-friendly hotel in San Francisco. Enjoy free Wi-Fi, breakfast (surcharge) and a 24-hour fitness centre. Our guests praise the pool and the ...
9/10 Wonderful! (5,706 reviews)
Amazing!

Reviewed on 8 May 2026

Holiday Inn Golden Gateway by IHG
Handlery Union Square Hotel

Handlery Union Square Hotel

3.5 out of 5
351 Geary St San Francisco CA
The price is ₹15,004 per night from 25 May to 26 May
₹15,004
₹17,659 total
25 May - 26 May
includes taxes & fees
Stay at this family-friendly hotel in San Francisco. Enjoy free Wi-Fi, a fitness centre and valet parking (surcharge). Our guests praise the pool and the helpful ...
8.8/10 Excellent! (3,102 reviews)
We really enjoyed the stay here! The staff were super friendly and helpful. The retro vibe was fun, beds comfy and the sauna was a wonderful bonus! Lots of restaurants they partner with and the location is excellent. Easy walk from the BART and very close to the action. Would definitely stay here ...

Reviewed on 8 May 2026

Handlery Union Square Hotel
Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco

4 out of 5
424 Clay St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is ₹11,937 per night from 28 May to 29 May
₹11,937
₹14,049 total
28 May - 29 May
includes taxes & fees
Stay at this business-friendly hotel in San Francisco. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff and the ...
9/10 Wonderful! (3,120 reviews)
Good location and in a decent area. Staff was nice and friendly. Hotel was clean and rooms were clean. I recommend this place!

Reviewed on 8 May 2026

Club Quarters Hotel in San Francisco
Hyatt Regency San Francisco

Hyatt Regency San Francisco

4 out of 5
5 Embarcadero Center San Francisco CA
The price is ₹20,640 per night from 25 May to 26 May
₹20,640
₹28,625 total
25 May - 26 May
includes taxes & fees
Stay at this business-friendly hotel in San Francisco. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (2,219 reviews)
So, there are three Hyatt's in San Francisco. My reservation was for the Hyatt Regency San Francisco, at Embarcadero Center. There is also a Hyatt Regency San Francisco Airport, and Hyatt SOMA. I asked if there was a hotel shuttle from the airport, for Hyatt Regency San Francisco, and was told yes. ...

Reviewed on 6 May 2026

Hyatt Regency San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Downtown South San Francisco

Aerial View Of Urban Neighborhood

Noe Valley

Appreciated for its churches and architecture, you might consider exploring Noe Valley. Check out the variety of things to see and do like 22nd St Hill, and jump on the metro at Church St & Clipper St Stop or Church St & 24th St Stop to get around the city.

Noe Valley
Mission District

Mission District

3.5/5(11 area reviews)

You might enjoy the bars while in Mission District. San Francisco Public Library is a notable sight, and you can get around town at 16th Street Mission Station or 24th Street Mission Station to see more of the city.

Mission District
Potrero Hill

Potrero Hill

The live music and architecture are just a few things visitors like about Potrero Hill. San Francisco Bay and Museum of Craft & Design are worthwhile spots to check out, and you can hop on the metro at 20th Street Station or 23rd Street Station to get around the larger area.

Potrero Hill
Sunset District

Sunset District

3.5/5(6 area reviews)

Consider exploring the beaches in Sunset District. If sightseeing is on the list, Ocean Beach is a top attraction. Hop on the metro at Judah Street & Sunset Boulevard Station or Judah St & 34th Ave Stop to see more of the area.

Sunset District
South of Market

South of Market

3.5/5(115 area reviews)

Gourmet restaurants great entertainment and top sights from Oracle Park to San Francisco Bay – discover South of Market, a destination also famous for its shopping.

South of Market
 Japanese Tea Garden in Golden Gate Park reflecting in one of the koi ponds. San Fancisci, California

Golden Gate

If you're spending time in Golden Gate, check out sights like San Francisco Botanical Garden or Japanese Tea Garden and hop on the metro to see more of the city at Irving St & 9th Ave Stop or Irving St & 8th Ave Stop.

Golden Gate


Downtown South San Francisco Travel Guide