Downtown South San Francisco Trip

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to ₹43,962 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Where to stay in Downtown South San Francisco

Find the best Downtown South San Francisco areas and neighborhoods for the activities you enjoy most. Learn more about Downtown South San Francisco
Union Square featuring a skyscraper and a city

Union Square

4/5(287 area reviews)

One of the biggest and most popular shopping plazas across the United States.

Find hotels in Union Square

Top hotels in Downtown South San Francisco

La Quinta Inn & Suites by Wyndham San Francisco Airport N

La Quinta Inn & Suites by Wyndham San Francisco Airport N

3 out of 5
20 Airport Blvd South San Francisco CA
Fully refundableReserve now, pay when you stay
The price is ₹8,729 per night from 13 Dec to 14 Dec
₹8,729
₹10,264 total
13 Dec - 14 Dec
includes taxes & fees
8/10 Very Good! (2,036 reviews)
Staff excellent, Location very good, rooms clean but some small damage.

Reviewed on 1 Dec 2025

La Quinta Inn & Suites by Wyndham San Francisco Airport N
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
Fully refundable
The price is ₹10,709 per night from 14 Dec to 15 Dec
₹10,709
₹12,604 total
14 Dec - 15 Dec
includes taxes & fees
8.8/10 Excellent! (4,928 reviews)
Easily accessible and I liked having the bar/restaurant in the lobby

Reviewed on 6 Dec 2025

Holiday Inn Golden Gateway by IHG
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is ₹11,611 per night from 18 Dec to 19 Dec
₹11,611
₹17,373 total
18 Dec - 19 Dec
includes taxes & fees
8.8/10 Excellent! (7,147 reviews)
room was clean and friendly staff

Reviewed on 3 Dec 2025

Hotel Riu Plaza Fisherman's Wharf
See all 4,768 properties in Downtown South San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Downtown South San Francisco holiday package cost?
From just . Yes, you read that right. Our Downtown South San Francisco holiday packages are a simple way to make your dollar go further. Combine your favourite hotels, flights and car rentals and get to know this popular destination.
How do I get a cheap travel package to Downtown South San Francisco?
Bundle your bookings with Expedia to save on your next big adventure. With more than 550 airlines and 1,000,000 properties globally, your Downtown South San Francisco holiday package can be tailored exactly to suit your travel style. With all those extra dollars, why not add one or two interesting tours and activities? It's an easy way to unlock even more bargains. That dream holiday to Downtown South San Francisco is much closer than you thought!
Where should I stay in Downtown South San Francisco?
A trip to Downtown South San Francisco wouldn't be complete without seeing South San Francisco Convention Centre, Sees Candies and K1 Speed San Francisco. Spend your nights close to these top attractions and make sightseeing easy.
What are the top hotels in Downtown South San Francisco?
Book a stay at Airport Inn. It's one of this area's most sought-after hotels. Another well-known option in Downtown South San Francisco is Rustic/modern Design, Oasis City Getaway.
How far in advance should I book my Downtown South San Francisco holiday?
Travellers are generally able to look up international airfares on Expedia up to a year in advance of departure. Booking at the last minute? With a stroke of luck, it's still possible to purchase a cheaper ticket only weeks before your journey.
What does an Expedia Downtown South San Francisco travel package include?
With Expedia, you can choose a combination of hotels, flights and car rentals to build your perfect Downtown South San Francisco travel package. Once you've made your booking, you can add on all the fun stuff like activities and tours. Don't forget, the more you bundle, the more cash you'll save!
What should I know before booking a Downtown South San Francisco travel package?
When you book your hotels, flights and car rentals together, you'll land great discounts. Whether you're organising an outdoor getaway in a chalet or prefer to stay in a ritzy city hotel, Expedia can help make it happen.
Can I choose my airline with a Downtown South San Francisco Expedia holiday package?
Definitely. Expedia has more than 550 airline partners to select from all over the world. With all that choice, finding the ideal carrier to whisk you away to Downtown South San Francisco will be a cinch.
If I'm not able to travel, can I cancel my Downtown South San Francisco holiday package?
It's impossible to predict what tomorrow might bring, so it's comforting to know that you can change or cancel your Downtown South San Francisco holiday package. If you booked in the last 24 hours, you may be entitled to a refund. If it's an older booking, your hotel, airline or car rental company may charge a fee. Visit our Customer Service Portal for more information.

Popular places to visit

Golden Gate Bridge featuring a suspension bridge or treetop walkway, night scenes and general coastal views

Golden Gate Bridge

Arguably the most famous and enduring icon of San Francisco which you can drive along or even explore on foot.

Golden Gate Bridge
Pier 39 featuring street scenes, a city and signage

Pier 39

Enjoy the street entertainment, the souvenir shops and the rides at this waterside attraction, where you can see sea lions playing.

Pier 39
Moscone Convention Center

Moscone Convention Center

During your trip, find out what's happening in Moscone Convention Center, a top convention centre in San Francisco. Discover the fascinating museums and shops in this vibrant area.

Moscone Convention Center
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.