South Main Travel Guide
Houston
Visit South Main
Popular places to visit
NRG Stadium
Catch an event at NRG Stadium during your trip to Houston. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
George R. Brown Convention Center
During your trip, find out what's happening in George R. Brown Convention Center, a top convention centre in Houston. Experience the entertainment choices and acclaimed art galleries in this vibrant area.
Daikin Park
Catch an event at Daikin Park during your trip to Houston. Experience the entertainment choices and lively festivals in this vibrant area.
Toyota Center
Catch an event at Toyota Center during your trip to Houston. Experience the acclaimed theatre scene and entertainment choices in this vibrant area.
NASA Johnson Space Center
After visiting NASA Johnson Space Center, make a plan to see the other sights and activities in Houston. Amble around the area's lakeside or attend a sporting event.
Space Center Houston
Visit the heart of the American space industry in the control centre that put man on the moon.
Top hotels in South Main
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
I was very disappointed in this Doubletree! The room had a musty smell and it desperately needs updating. The bathroom looked like it needed a deep cleaning. The bed was like sleeping on a brick. Don’t take a truck and try to park in the garage. The roof is so low it broke our antenna. We stayed ...
Reviewed on 15 Mar 2026
Hotel Zaza Houston Museum District
Although I had booked a Standard Room, 1 queen bed, I was placed in a petite queen. I must congratulate Hotel Zsa Zsa in providing me with the smallest hotel room that I have ever occupied. That includes many hotel rooms in Italy which has notoriously small rooms. If you have the slightest problem ...
Reviewed on 15 Mar 2026
The Royal Sonesta Houston Galleria
Staff was amazing. Facility was great.
Reviewed on 15 Mar 2026
Club Quarters Hotel Downtown, Houston
Staff very friendly and very convenient for the event I attended.
Reviewed on 15 Mar 2026
Blossom Hotel Houston, Curio Collection by Hilton
I got there early waited 3 hours to check in and then at check in time was told my room wasn’t ready so I had to wait another 9 hours I was not checked into my room til almost 10:30 at night
Reviewed on 15 Mar 2026
The Whitehall Houston
Great location, my room door didn’t close properly, it closed but it didn’t “seal” so I could all the noise from elevators. A/C super loud, bathtub handle were loose, empty soap container, Coffe machine broken with a used coffee pod inside. I won’t come back here
Reviewed on 15 Mar 2026
Other neighbourhoods around South Main
Astrodome
While you're in Astrodome, take in top sights like NRG Stadium or NRG Astrodome, and hop on the metro to see more of the city at Stadium Park/Astrodome Station or Smith Lands Station.
Texas Medical Center
Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.
Museum District
Known for its abundant dining options and interesting museums, there's plenty to explore in Museum District. Top attractions like Children's Museum of Houston and Houston Natural Science Museum are major draws, and you can catch the metro at Museum District Station or Hermann Park/Rice U Station to see more of the city.
Greenway Plaza-Upper Kirby
Greenway Plaza-Upper Kirby is known for its abundant dining options, and you can plan a trip to Richmond Avenue and Highland Village while you're in town.
South Central Houston
If you're spending time in South Central Houston, check out sights like Children's Museum of Houston or Houston Natural Science Museum and hop on the metro to see more of the city at Elgin/Third Ward Station or TSU/UH Athletics District Station.
Montrose
Unique features of Montrose include the theatres and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.
