Search Hotels in East Side Pioneers, Rochester

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
12 Dec - 13 Dec
Tomorrow
13 Dec - 14 Dec
This weekend
12 Dec - 14 Dec
Next weekend
19 Dec - 21 Dec

Filter by

Guest rating
Guest rating
Star rating

Our top choices for East Side Pioneers hotels

Indoor pool, open 5:00 AM to 10:00 PM, pool loungers
Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area
3.5 star property
East Side Pioneers
9.6 out of 10, Exceptional, (543)
"Very courteous staff, loved the valet guy!"
United States
Jean
The price is ₹15,418
₹17,750 total
includes taxes & fees
27 Dec - 28 Dec
Hilton Rochester Mayo Clinic Area
Two-Bedroom Apartment - Mobility Accessible/Non-Smoking | In-room safe, individually furnished, desk, laptop workspace
Broadway Plaza, Trademark Collection by Wyndham

Broadway Plaza, Trademark Collection by Wyndham

Broadway Plaza, Trademark Collection by Wyndham
3.0 star property
East Side Pioneers
9.2 out of 10, Wonderful, (167)
"Great staff, clean room, spacious kitchen and living room."
United States
silvia
The price is ₹13,420
₹15,449 total
includes taxes & fees
27 Dec - 28 Dec
Broadway Plaza, Trademark Collection by Wyndham
Exterior
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG
3.5 star property
East Side Pioneers
8.8 out of 10, Excellent, (884)
"Great room and stay!"
United States
Trevor
The price is ₹6,868
₹7,907 total
includes taxes & fees
26 Dec - 27 Dec
Hotel Indigo Rochester – Mayo Clinic Area by IHG
View from property
Kahler Grand Hotel

Kahler Grand Hotel

Kahler Grand Hotel
3.0 star property
Downtown Rochester, 1.3 km from East Side Pioneers
8.4 out of 10, Very good, (1821)
"Staff was friendly and helpful! Will continue to stay here while at the Mayo, "
United States
Gayle
The price is ₹12,064
₹13,889 total
includes taxes & fees
27 Dec - 28 Dec
Kahler Grand Hotel
Serves lunch, dinner and happy hour
AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic
3.0 star property
3 km from East Side Pioneers
8.2 out of 10, Very good, (1131)
"Great location and value"
United States
Michelle
The price is ₹6,595
₹7,593 total
includes taxes & fees
26 Dec - 27 Dec
AmericInn by Wyndham Rochester Near Mayo Clinic
Free daily full breakfast
Econo Lodge Mayo Clinic Area

Econo Lodge Mayo Clinic Area

Econo Lodge Mayo Clinic Area
2.0 star property
3.4 km from East Side Pioneers
9.0 out of 10, Wonderful, (895)
"Good breakfast..shuttle service is excellent..super nice staff.."
United States
DALE K
The price is ₹5,703
₹6,566 total
includes taxes & fees
2 Jan - 3 Jan 2026
Econo Lodge Mayo Clinic Area
Front of property
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
3.0 star property
7.3 km from East Side Pioneers
7.2 out of 10, Good, (1018)
"Breakfast was good. The staff was great. "
United States
Kjirsta
The price is ₹6,477
₹7,457 total
includes taxes & fees
14 Dec - 15 Dec
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Courtyard
EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG
4.0 star property
Kutzky Park, 2.3 km from East Side Pioneers
9.4 out of 10, Exceptional, (956)
"Rooms are comfortable and staff was was so professional and helpful."
United States
William
The price is ₹9,141
₹10,704 total
includes taxes & fees
13 Dec - 14 Dec
EVEN Hotel Rochester - Mayo Clinic Area by IHG
BBQ/picnic Area
Aspen Suites

Aspen Suites

Aspen Suites
3.0 star property
2.6 km from East Side Pioneers
9.0 out of 10, Wonderful, (688)
"I always stay at this hotel , love it clean comfortable rooms, they gave us vouchers for 4 free meals for Thanksgiving dinner"
United States
Cindy
The price is ₹13,943
₹16,854 total
includes taxes & fees
9 Jan - 10 Jan 2026
Aspen Suites
In-room safe, desk, iron/ironing board, free cots/infant beds
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
2.0 star property
6.4 km from East Side Pioneers
7.8 out of 10, Good, (1001)
"Front staff are so kind and efficient. "
United States
Brenda
The price is ₹5,735
₹6,603 total
includes taxes & fees
27 Dec - 28 Dec
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
Indoor pool
Residence Inn by Marriott Rochester Mayo Clinic Area South

Residence Inn by Marriott Rochester Mayo Clinic Area South

Residence Inn by Marriott Rochester Mayo Clinic Area South
3.0 star property
3.4 km from East Side Pioneers
9.6 out of 10, Exceptional, (246)
"Very nice motel "
United States
Jim
The price is ₹9,678
₹11,142 total
includes taxes & fees
20 Dec - 21 Dec
Residence Inn by Marriott Rochester Mayo Clinic Area South
Free daily on-the-go breakfast
Super 8 by Wyndham Rochester Mayo Clinic Area

Super 8 by Wyndham Rochester Mayo Clinic Area

Super 8 by Wyndham Rochester Mayo Clinic Area
2.0 star property
3.7 km from East Side Pioneers
7.8 out of 10, Good, (1002)
"Great Stay"
United States
Aweng
The price is ₹4,588
₹5,282 total
includes taxes & fees
30 Dec - 31 Dec
Super 8 by Wyndham Rochester Mayo Clinic Area
Property entrance
Country Inn & Suites Rochester South Mayo Clinic

Country Inn & Suites Rochester South Mayo Clinic

Country Inn & Suites Rochester South Mayo Clinic
3.0 star property
5.8 km from East Side Pioneers
8.4 out of 10, Very good, (1003)
"Clean room, fun staff."
United States
Thomas
The price is ₹8,717
₹10,036 total
includes taxes & fees
12 Jan - 13 Jan 2026
Country Inn & Suites Rochester South Mayo Clinic
Lobby lounge
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
3.0 star property
Kutzky Park, 2.4 km from East Side Pioneers
8.6 out of 10, Excellent, (934)
"Room was comfortable and convenient.Staff was exceptional.I will stay here when I am next in town."
United States
Rachel
The price is ₹8,456
₹9,736 total
includes taxes & fees
27 Dec - 28 Dec
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
Reception
Spark by Hilton Rochester South

Spark by Hilton Rochester South

Spark by Hilton Rochester South
3.0 star property
7 km from East Side Pioneers
9.4 out of 10, Exceptional, (309)
"Great place"
United States
Abidemi
The price is ₹6,217
₹7,158 total
includes taxes & fees
4 Jan - 5 Jan 2026
Spark by Hilton Rochester South
Coffee service
Aspen Select

Aspen Select

Aspen Select
3.5 star property
2.6 km from East Side Pioneers
8.4 out of 10, Very good, (1001)
"Beds are very comfortable!"
United States
Laurie
Aspen Select
Coffee service
MainStay Suites Rochester South Mayo Clinic

MainStay Suites Rochester South Mayo Clinic

MainStay Suites Rochester South Mayo Clinic
2.5 star property
5.6 km from East Side Pioneers
7.0 out of 10, Good, (89)
"Staff is friendly "
United States
Merry
The price is ₹4,939
₹5,686 total
includes taxes & fees
15 Dec - 16 Dec
MainStay Suites Rochester South Mayo Clinic
Iron/ironing board, free cots/infant beds, free WiFi, bed sheets
Baymont by Wyndham Rochester Mayo Clinic Area

Baymont by Wyndham Rochester Mayo Clinic Area

Baymont by Wyndham Rochester Mayo Clinic Area
2.5 star property
2.3 km from East Side Pioneers
7.2 out of 10, Good, (717)
"Spotless clean"
United States
Brit
The price is ₹5,353
₹6,162 total
includes taxes & fees
2 Jan - 3 Jan 2026
Baymont by Wyndham Rochester Mayo Clinic Area
Indoor pool, open 9:00 AM to 10:00 PM, pool umbrellas, pool loungers
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
2.5 star property
3.8 km from East Side Pioneers
8.2 out of 10, Very good, (785)
"Great place to stay. Freindly staff"
United States
joel
The price is ₹8,071
₹9,291 total
includes taxes & fees
2 Jan - 3 Jan 2026
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
City view from property
Marriott Rochester Mayo Clinic

Marriott Rochester Mayo Clinic

Marriott Rochester Mayo Clinic
3.5 star property
Downtown Rochester, 1.2 km from East Side Pioneers
8.4 out of 10, Very good, (523)
"it was a fantastic "
United States
Paul
The price is ₹15,272
₹17,582 total
includes taxes & fees
13 Dec - 14 Dec
Marriott Rochester Mayo Clinic
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in East Side Pioneers

Find the best East Side Pioneers areas for the activities you enjoy most.
Rochester showing skyline and a city
Photo by Howard Lower Photography
Open Photo by Howard Lower Photography

Downtown Rochester

If you're spending some time in Downtown Rochester, Mayo Civic Center and Rochester Civic Theater are top sights worth seeing.

Kutzky Park

While there might not be top attractions in Kutzky Park, you can explore the larger area and discover places like Soldiers Field Veterans Memorial and Mayo Civic Center.

Rochester which includes a river or creek and forests
Photo by Chad Johnson
Open Photo by Chad Johnson

Historic Southwest

While visiting Historic Southwest, you might make a stop by sights like Soldiers Field Veterans Memorial and Plummer House.

Slatterly Park

While Slatterly Park isn't home to many top sights, Rochester Art Center and Soldiers Field Veterans Memorial are some notable places to visit nearby.

Northrup

When in Northrup, you can plan a visit to Rochester Civic Theater and Mayo Civic Center, some noteworthy sights in the nearby area.

Top East Side Pioneers Hotel Reviews

Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

10/10 Excellent
"Staff was friendly and helpful. Clean room."
Matthew 7-night trip
Posted 2 days ago
Hyatt House Rochester/Mayo Clinic Area

Explore a world of travel with Expedia

Frequently asked questions

What's it like in East Side Pioneers?
Travellers are sure to enjoy a stay in Rochester's East Side Pioneers neighbourhood. Are you looking for East Side Pioneers travel tips? Make sure that you visit Rochester Art Center and Rochester Civic Theater while you're in the neighbourhood.
What's the best accommodation in East Side Pioneers?
Based on Expedia customer reviews, Hilton Rochester Mayo Clinic Area is the highest ranked property in East Side Pioneers. This hotel is a short 6-minute walk from Mayo Clinic, and it offers a full-service spa and 2 restaurants. Another favourite option in the neighbourhood is Hotel Indigo Rochester – Mayo Clinic Area by IHG.
How many hotels should I expect to find in East Side Pioneers?
If you're searching for places to stay in Rochester, choose from one of Expedia's 17 hotels and other accommodation options in East Side Pioneers.
If I need to cancel my hotel reservation in East Side Pioneers, will I receive a refund?
Yes! The majority of room reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of booking. Put your dates in and click on "Search", then use the filter option "fully refundable" to get the best deals in East Side Pioneers.
What can I see and do in this Rochester neighbourhood?
Spend some time exploring the natural setting of East Side Pioneers with a visit to Silver Lake Park and Mayo Park. You could also plan a visit to Rochester Art Center or Rochester Civic Theater while you're in the neighbourhood. A few places to visit in the area around East Side Pioneers include Mayo Civic Center, Rochester Public Library and Shops University Square. While you're out sightseeing, Plummer Building and Soldiers Field Veterans Memorial are a couple of additional sights to visit in Rochester.