A public park with a fountain featuring bronze sculptures of mythological figures, surrounded by trees and a large building in the background.

Search Spa Hotels in Downtown St. Louis

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Downtown St. Louis Spa Hotels

Our top choices for Downtown St. Louis hotels with a spa

A bathroom with a white sink, dark wooden door, and a shower area with striped glass walls.

1. Truitt Hotel

Truitt Hotel
2.0 star property
Lafayette Square
10.0 out of 10, Exceptional, (13 reviews)
The price is ₹16,097
₹19,541 total
includes taxes & fees
27 Sept - 28 Sept
Truitt Hotel
A reception desk with a wooden finish and the name "IDOL WOLF" on it.

2. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
4.5 star property
Downtown West
9.0 out of 10, Wonderful, (2,117 reviews)
  • cleanliness
    Discover spa services, a steam room, and an Olympic-sized indoor pool at this modern hotel, all designed for rejuvenating getaways.
The price is ₹13,764
₹16,573 total
includes taxes & fees
18 Oct - 19 Oct
21C Museum Hotel St Louis
A couple relaxing by a window overlooking a bridge and water.

3. Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
5.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1,001 reviews)
  • cleanliness
    Discover a tranquil haven with 12 treatment rooms, outdoor pool, and breathtaking views at this rejuvenating spa retreat.
The price is ₹35,931
₹42,014 total
includes taxes & fees
4 Oct - 5 Oct
Four Seasons Hotel St Louis
A modern kitchen with wooden cabinets, a central island, and framed artwork on the walls.

4. The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
5.0 star property
Clayton
9.2 out of 10, Wonderful, (586 reviews)
  • cleanliness
    Revel in a rejuvenating spa retreat with aromatherapy treatments and hot stone massages at this luxury St. Louis hotel.
The price is ₹61,265
₹71,520 total
includes taxes & fees
11 Oct - 12 Oct
The Ritz-Carlton, St. Louis
A modern spa with a curved reception desk, a large mirror, and a decorative water feature.

5. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.6 out of 10, Excellent, (1,061 reviews)
  • cleanliness
    Riverside wellness oasis offers full-service spa with aromatherapy and hydrotherapy for a restorative retreat.
The price is ₹14,301
₹18,302 total
includes taxes & fees
12 Oct - 13 Oct
Ameristar Casino Resort and Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Choose what matters most at spa hotels in Downtown St. Louis

Pool
Breakfast included

Top Downtown St. Louis Hotel Reviews

Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch

8/10 Good
"Recently had the pleasure of staying at the Pennywheel hotel. The staff was excellent, self parking and valet were readily available. The hotel is a 5-7 min walk from St Louis arch as well as Busch stadium. It is also centrally located near major highways so you can explore other parts if the city and state."
Gregory 4-night trip
Posted 7 hours ago
Hilton Pennywell St. Louis at the Arch

Frequently asked questions

Looking to holiday at a spa hotel in Downtown St. Louis?
Forget the stress of everyday life and book yourself a hotel with a spa. Travellers love the historical sites and restaurants in Downtown St. Louis. Make sure you pay a visit to the museums during your stay. Spa hotels are the perfect way to break out of your daily routine and add a layer of luxury to your holiday.
What is the best spa hotel in Downtown St. Louis?
Four Seasons Hotel St Louis is a top luxury spa hotel featuring a rooftop terrace, a 24-hour fitness centre, a hair salon and a bar. Enjoy a facial, body scrub or body wrap at the on-site spa.
How many spa hotels are there in Downtown St. Louis?
Among Expedia's 152 accommodation options in Downtown St. Louis, there is 1 spa hotel.
What's there to see and do in Downtown St. Louis?
Experience Downtown St. Louis and visit Gateway Arch, Gateway Arch National Park and Ballpark Village. If you have extra time while you're in the area, you might want to stop by Federal Reserve Bank of St. Louis and Gateway Arch Visitor Center.
What is a Downtown St. Louis spa hotel?
Spa hotels in Downtown St. Louis have on-site spas offering services such as massages and a choice of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are ideal if you are looking for some R&R during your holiday.

Explore a world of travel with Expedia