A public park with a fountain featuring bronze sculptures of mythological figures, surrounded by trees and a large building in the background.

Search Spa Hotels in Downtown St. Louis

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Downtown St. Louis Spa Hotels

This weekend
6 Nov - 8 Nov
Next weekend
13 Nov - 15 Nov

Our top choices for Downtown St. Louis hotels with a spa

A modern hotel lobby with a glass facade, seating area, and a staircase.

1. Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
5.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1,000 reviews)
"Exactly what you would expect from a four seasons hotel. Fantastic, all the way around!"
United States
JEFFREY
The price is ₹35,428
₹41,425 total
includes taxes & fees
8 Nov - 9 Nov
Four Seasons Hotel St Louis
A reception area with a wooden counter, a staircase with a colorful mural, and a sign reading 'Locust Street Athletic and Swim Club.'

2. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
4.5 star property
Downtown West, 1.4 km from Downtown St. Louis
9.0 out of 10, Wonderful, (2,148 reviews)
"Wonderful Stay!"
United States
A.R.
The price is ₹13,544
₹16,310 total
includes taxes & fees
15 Nov - 16 Nov
21C Museum Hotel St Louis
A well-lit lobby with a chandelier, potted plants, and a seating area.

3. Truitt Hotel

Truitt Hotel
2.0 star property
Lafayette Square, 2.7 km from Downtown St. Louis
9.8 out of 10, Exceptional, (27 reviews)
"Amazing stay, gorgeous rooms and buildings, perfect getaway"
United States
Gabrielle
The price is ₹15,872
₹19,267 total
includes taxes & fees
8 Nov - 9 Nov
Truitt Hotel
A hotel room with two beds, a framed picture on the wall, and a window with curtains.

4. The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
5.0 star property
12.6 km from Downtown St. Louis
9.2 out of 10, Wonderful, (587 reviews)
"Incredible stay! Loved the room, the staff were great, and the amenities were amazing! Definitely recommend staying here!"
United States
Kennedy
The price is ₹56,590
₹66,062 total
includes taxes & fees
13 Nov - 14 Nov
The Ritz-Carlton, St. Louis
A reception desk with a modern design, a large abstract wall, and a seating area with a chair.

5. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
30.2 km from Downtown St. Louis
8.6 out of 10, Excellent, (1,092 reviews)
"Great place"
United States
Samuel
The price is ₹15,040
₹19,145 total
includes taxes & fees
22 Nov - 23 Nov
Ameristar Casino Resort and Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Choose what matters most at spa hotels in Downtown St. Louis

Pool
Breakfast included

Top Downtown St. Louis Hotel Reviews

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

10/10 Excellent
"Use the pool at dinner time when children are not around... otherwise, do not use the pool. Breakfast was very good. Staff was friendly and helpful!!!"
Amy 1-night trip
Posted 17 hours ago
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Frequently asked questions

Looking to holiday at a spa hotel in Downtown St. Louis?
Forget the stress of everyday life and book yourself a hotel with a spa. Travellers love the historical sites and restaurants in Downtown St. Louis. Make sure you pay a visit to the museums during your stay. Spa hotels are the perfect way to break out of your daily routine and add a layer of luxury to your holiday.
What is the best spa hotel in Downtown St. Louis?
Four Seasons Hotel St Louis is a top luxury spa hotel featuring a rooftop terrace, a 24-hour fitness centre, a hair salon and a bar. Enjoy a facial, body scrub or body wrap at the on-site spa.
How many spa hotels are there in Downtown St. Louis?
Among Expedia's 150 accommodation options in Downtown St. Louis, there is 1 spa hotel.
What's there to see and do in Downtown St. Louis?
Experience Downtown St. Louis and visit Old Courthouse, Gateway Arch National Park and Ballpark Village. If you have extra time while you're in the area, you might want to stop by Gateway Arch and Federal Reserve Bank of St. Louis.
What is a Downtown St. Louis spa hotel?
Spa hotels in Downtown St. Louis have on-site spas offering services such as massages and a choice of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are ideal if you are looking for some R&R during your holiday.

Explore a world of travel with Expedia