Compare and book 5 Star hotels in Southern Maryland, Maryland
Change your mind
Be picky
Check availability on Southern Maryland 5 Star Hotels
Top Southern Maryland 5 Star Hotels

Swanendele Inn at St. Mary's Maryland
Swanendele Inn at St. Mary's Maryland

The Inn at Tacaro Estate
The Inn at Tacaro Estate
Explore similar 4-star hotels

Gaylord National Resort & Convention Center
Learn more about Southern Maryland
Explore the family-friendly area of Southern Maryland—a scenic waterfront, sports teams and sights from Running Hare Vineyard to Budds Motorcross Speedway.

Find out more about Southern Maryland
Find out more about Southern Maryland
Stay in Luxury: 5 Star Hotels in Southern Maryland
There's nothing wrong with enjoying the finer things in life. Indulge your every desire on your upcoming leisure time. Treat yourself with a stay in a 5-star hotel during your Southern Maryland trip. You'll join the multitudes of holidaymakers who have made Southern Maryland so fashionable recently. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Don't wait any longer. Reserve one of our 5-star hotels in Southern Maryland and indulge in the finer things in life for a while.
5-Star Hotels in Southern Maryland
You'll have a wonderful time at one of these 5-star hotels. Exceptional customer care, luxurious bedding, and deeply relaxing spa offerings are waiting for you. You're sure to find exactly the accommodation you need. You can also expect excellent customer service from these hotels, so get ready for a wonderful adventure. What kind of amenities will make your stay a wonderful one? 24-hour room service, so you can order that berry tart in the wee hours of the morning? A body scrub that will leave you feeling refreshed and alive? Butler services? Whatever it is your heart desires, you're bound to find it here. Don't want to take our word for it? Explore our listings and pick the perfect accommodation for your needs.
But you aren't going to spend your entire holiday in your room, of course. You're in luck. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Southern Maryland are waiting for you to relax after an exciting day.
Make Your Escape
The results are in, and Southern Maryland 5-star hotels are the place to be when you book your next holiday. If you've been dreaming about a holiday set here, then go ahead and book it. It's time to plan your next great escape -- this is a great time to find 5-star hotel deals in Southern Maryland! Choose one of our Southern Maryland 5-star hotels today and soothe yourself in luxe surroundings at your convenience.
Expedia India is rated 4 stars by Feefo based on 1038 reviews
Top Southern Maryland Hotel Reviews
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Hotels in Southern Maryland by Star Rating
Areas of Southern Maryland
Accommodation near Southern Maryland attractions
- Hotels near George Washington's Mount Vernon
- Hotels near St. Mary's College of Maryland
- Hotels near Maryland International Raceway
- Hotels near Budds Motorcross Speedway
- Hotels near Calvert Cliffs State Park
- Hotels near Breezy Point Beach
- Hotels near Chesapeake Beach Water Park
- Hotels near Prince George's Community College
- Hotels near Rod n Reel Charter Fishing
- Hotels near National Children's Museum
- Hotels near Elms Beach Park
- Hotels near Goose Bay Marina
- Hotels near Lake Presidential Golf Club
Choose Your Southern Maryland Hotel Style
- Beach Resorts & Hotels in Southern Maryland
- Business Hotels in Southern Maryland
- Cheap Hotels in Southern Maryland
- Family-Friendly Hotels in Southern Maryland
- Golf Hotels in Southern Maryland
- Historic Hotels in Southern Maryland
- Hotels Suites in Southern Maryland
- Hotels near Museums in Southern Maryland
- Hotels with Air Conditioning in Southern Maryland
- Hotels with Balcony in Southern Maryland
- Hotels with Breakfast in Southern Maryland
- Hotels with Connecting Rooms in Southern Maryland
- Hotels with Entertainment in Southern Maryland
- Hotels with Gym in Southern Maryland
- Hotels with Hot Tubs in Southern Maryland
- Hotels with Indoor Pools in Southern Maryland
- Hotels with Laundry Service in Southern Maryland
- Hotels with Parking in Southern Maryland
- Hotels with Parking in Southern Maryland
- Hotels with Restaurant in Southern Maryland
- Hotels with Swimming Pool in Southern Maryland
- Hotels with Views in Southern Maryland
- Hotels with Wifi in Southern Maryland
- Hotels with a Bar in Southern Maryland
- Luxury Hotels in Southern Maryland
- Marina Hotels in Southern Maryland
- Pet-Friendly Hotels in Southern Maryland
- Romantic Hotels in Southern Maryland
- Shopping Hotels in Southern Maryland
- Spa Hotels in Southern Maryland
- Sports Hotels in Southern Maryland
- Wedding Hotels in Southern Maryland
Explore more hotels
- La Quinta Inn & Suites by Wyndham Lexington Park - Patuxent
- Executive Inn And Suites
- Quality Suites
- Best Western La Plata Inn
- Motel 6 Camp Springs, DC - South Camp Springs
- Sleep Inn & Suites Near Joint Base Andrews - Washington Area
- Holiday Inn Express Waldorf by IHG
- Rod 'N' Reel Resort
- Quality Inn Near Joint Base Andrews - Washington Area
- SureStay by Best Western Prince Frederick
- Quality Inn Solomons - Beacon Marina
- Hilton Garden Inn Solomons
- Red Carpet Inn Indian Head
- Springhill Suites by Marriott Prince Frederick
- Holiday Inn Express Prince Frederick by IHG
More ways to book
Expedia's Latest Trends
- Visit White Mountains
- Visit Long Island
- Visit Silicon Valley
- Visit Oahu
- Visit Wine Country
- Visit Southeast Florida
- Visit National Harbor
- Visit Capitol Hill
- Visit Northern Arkansas
- Visit Bethesda
- Visit Arlington
- Visit Plantation Key
- Visit Downtown Washington D.C.
- Visit Bay Area
- Visit Dallas-Fort Worth Metroplex DFW
- Visit Hawaii Island
- Visit Coachella Valley