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Our top choices for Rome City Centre 5-star hotels

Sauna, steam room, Turkish bath/hammam, body treatments, aromatherapy
The Westin Excelsior, Rome

The Westin Excelsior, Rome

The Westin Excelsior, Rome
5.0 star property
Rome City Centre
8.2 out of 10, Very good, (745)
"Spacious rooms!!!"
United States
Milana
The price is ₹32,961
₹38,380 total
includes taxes & fees
14 Jan - 15 Jan 2026
The Westin Excelsior, Rome
Exterior
NH Collection Roma Palazzo Cinquecento

NH Collection Roma Palazzo Cinquecento

NH Collection Roma Palazzo Cinquecento
5.0 star property
Rome City Centre
9.0 out of 10, Wonderful, (1000)
"The hotel was the best location to be at. Amazing stay and so convenient."
United States
Jalin
The price is ₹26,249
₹30,997 total
includes taxes & fees
11 Jan - 12 Jan 2026
NH Collection Roma Palazzo Cinquecento
Restaurant
Sofitel Rome Villa Borghese

Sofitel Rome Villa Borghese

Sofitel Rome Villa Borghese
5.0 star property
Rome City Centre
9.2 out of 10, Wonderful, (968)
"Professional staff, luxurious surroundings, excellent location, very nice accommodations - all in all a great experience. "
Sweden
Daniel
The price is ₹36,043
₹41,770 total
includes taxes & fees
13 Jan - 14 Jan 2026
Sofitel Rome Villa Borghese
2 restaurants, Italian cuisine
Anantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World

Anantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World

Anantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World
5.0 star property
Rome City Centre
9.2 out of 10, Wonderful, (1002)
"incredible, no hotel compares to it. everything was perfect "
United States
Sana
The price is ₹56,372
₹64,132 total
includes taxes & fees
9 Jan - 10 Jan 2026
Anantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World
Exterior
InterContinental Rome Ambasciatori Palace by IHG

InterContinental Rome Ambasciatori Palace by IHG

InterContinental Rome Ambasciatori Palace by IHG
5.0 star property
Rome City Centre
9.6 out of 10, Exceptional, (157)
"Great Staff Great Location"
Canada
cristina
The price is ₹45,453
₹52,121 total
includes taxes & fees
10 Jan - 11 Jan 2026
InterContinental Rome Ambasciatori Palace by IHG
Property amenity
W Rome

W Rome

W Rome
5.0 star property
Rome City Centre
9.6 out of 10, Exceptional, (204)
"Amazing hotel, wonderful staff, convenience "
Canada
Anna
The price is ₹42,461
₹48,830 total
includes taxes & fees
5 Jan - 6 Jan 2026
W Rome
Exterior
Baglioni Hotel Regina - The Leading Hotels of the World

Baglioni Hotel Regina - The Leading Hotels of the World

Baglioni Hotel Regina - The Leading Hotels of the World
5.0 star property
Rome City Centre
9.0 out of 10, Wonderful, (500)
"Excellent hotel with great sraff"
United Kingdom
Gary
The price is ₹43,615
₹50,099 total
includes taxes & fees
7 Jan - 8 Jan 2026
Baglioni Hotel Regina - The Leading Hotels of the World
2 bars/lounges
Radisson Collection Hotel, Roma Antica

Radisson Collection Hotel, Roma Antica

Radisson Collection Hotel, Roma Antica
5.0 star property
Rome City Centre
9.6 out of 10, Exceptional, (147)
"Clean, good breakfast, walkable to major historical ruins"
Canada
Pam
The price is ₹22,099
₹26,432 total
includes taxes & fees
12 Jan - 13 Jan 2026
Radisson Collection Hotel, Roma Antica
Restaurant
Six Senses Rome

Six Senses Rome

Six Senses Rome
5.0 star property
Rome City Centre
9.6 out of 10, Exceptional, (58)
"Amazing staff, beautifully decorated hotel, super amenities. Truly wonderful find in the heart of Rome."
United States
Sergio Alfonso
The price is ₹106,153
₹118,891 total
includes taxes & fees
4 Jan - 5 Jan 2026
Six Senses Rome
Garden
Villa Agrippina Gran Meliá - The Leading Hotels of the World

Villa Agrippina Gran Meliá - The Leading Hotels of the World

Villa Agrippina Gran Meliá - The Leading Hotels of the World
5.0 star property
Rome City Centre
9.2 out of 10, Wonderful, (935)
"Beautiful hotel, very clean, staff so friendly and helpful Would definitely stay again!"
United Kingdom
debra jane
The price is ₹42,655
₹49,044 total
includes taxes & fees
8 Jan - 9 Jan 2026
Villa Agrippina Gran Meliá - The Leading Hotels of the World
View from property
Sina Bernini Bristol, Autograph Collection

Sina Bernini Bristol, Autograph Collection

Sina Bernini Bristol, Autograph Collection
5.0 star property
Rome City Centre
8.2 out of 10, Very good, (542)
"Amazing staff service and beautiful room "
United States
Samantha
The price is ₹33,100
₹38,534 total
includes taxes & fees
21 Dec - 22 Dec
Sina Bernini Bristol, Autograph Collection
Property entrance
Grand Hotel Palace

Grand Hotel Palace

Grand Hotel Palace
5.0 star property
Rome City Centre
9.0 out of 10, Wonderful, (1000)
"The location was amazing and the staff was really friendly. The restaurant in the hotel was really good too. "
United States
Anuj
The price is ₹19,301
₹23,354 total
includes taxes & fees
21 Dec - 22 Dec
Grand Hotel Palace
View from property
Palazzo Manfredi – Small Luxury Hotels of the World

Palazzo Manfredi – Small Luxury Hotels of the World

Palazzo Manfredi – Small Luxury Hotels of the World
5.0 star property
Rome City Centre
9.0 out of 10, Wonderful, (638)
"The rooftop restaurant for breakfast was amazing.. eat and enjoy the view of the coliseum, and archeological dig… Amazing food selection "
United States
Leslie
The price is ₹42,558
₹48,937 total
includes taxes & fees
7 Jan - 8 Jan 2026
Palazzo Manfredi – Small Luxury Hotels of the World
Terrace/patio
Hotel Raphaël – Relais & Châteaux

Hotel Raphaël – Relais & Châteaux

Hotel Raphaël – Relais & Châteaux
5.0 star property
Rome City Centre
9.2 out of 10, Wonderful, (1003)
"The staff, room, and amenities were all excellent."
United States
Jason
The price is ₹22,967
₹27,387 total
includes taxes & fees
22 Dec - 23 Dec
Hotel Raphaël – Relais & Châteaux
Terrace/patio
Hotel Locarno

Hotel Locarno

Hotel Locarno
5.0 star property
Rome City Centre
9.8 out of 10, Exceptional, (521)
"Great location Friendly "
United States
anthony yunchin
The price is ₹42,471
₹48,841 total
includes taxes & fees
15 Dec - 16 Dec
Hotel Locarno
Property amenity
Aleph Rome Hotel Curio Collection by Hilton

Aleph Rome Hotel Curio Collection by Hilton

Aleph Rome Hotel Curio Collection by Hilton
5.0 star property
Rome City Centre
9.4 out of 10, Exceptional, (464)
"Stunning property! "
United States
Kaitlin
The price is ₹32,811
₹38,215 total
includes taxes & fees
17 Dec - 18 Dec
Aleph Rome Hotel Curio Collection by Hilton
Restaurant
Palazzo Roma - The Leading Hotels of the World

Palazzo Roma - The Leading Hotels of the World

Palazzo Roma - The Leading Hotels of the World
5.0 star property
Rome City Centre
10.0 out of 10, Exceptional, (106)
"Great location, beautiful property, very well run and managed. "
United Kingdom
John
Palazzo Roma - The Leading Hotels of the World
Banquet hall
Hassler Roma

Hassler Roma

Hassler Roma
5.0 star property
Rome City Centre
9.6 out of 10, Exceptional, (154)
"We travel a lot one of the best hotels we’ve ever stayed in"
United States
Joel
The price is ₹129,294
₹144,347 total
includes taxes & fees
15 Dec - 16 Dec
Hassler Roma
Suite | Egyptian cotton sheets, premium bedding, down duvets, memory-foam beds
Palazzo Montemartini Rome, A Radisson Collection Hotel

Palazzo Montemartini Rome, A Radisson Collection Hotel

Palazzo Montemartini Rome, A Radisson Collection Hotel
5.0 star property
Rome City Centre
8.8 out of 10, Excellent, (713)
"Room was amazing and the service was top notch. Staff was attentive and friendly. Lorenzo was an exceptional staff. He remembered us during our stay and constantly checked in on us when he was on shift. "
Singapore
Alvin
The price is ₹22,871
₹27,281 total
includes taxes & fees
10 Jan - 11 Jan 2026
Palazzo Montemartini Rome, A Radisson Collection Hotel
Terrace/patio
NH Collection Roma Fori Imperiali

NH Collection Roma Fori Imperiali

NH Collection Roma Fori Imperiali
5.0 star property
Rome City Centre
9.4 out of 10, Exceptional, (212)
"Location"
United States
Trevon
The price is ₹39,952
₹46,070 total
includes taxes & fees
18 Dec - 19 Dec
NH Collection Roma Fori Imperiali
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Rome City Centre.
Bettoja Hotel Mediterraneo

Bettoja Hotel Mediterraneo

Via Cavour 15 Rome RM
The price is ₹17,485 per night from 21 Dec to 22 Dec
₹17,485
₹20,825 total
21 Dec - 22 Dec
includes taxes & fees
8.6/10 Excellent! (995 reviews)
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Top Rome City Centre Hotel Reviews

Find out more about Rome City Centre

Stay in Luxury: 5 Star Hotels in Rome City Centre

There's nothing wrong with enjoying the finer things in life. Indulge your every desire on your upcoming leisure time. Treat yourself with a stay in a 5-star hotel during your Rome City Centre trip. You'll join the multitudes of holidaymakers who have made Rome City Centre so fashionable recently. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Don't wait any longer. Reserve one of our 5-star hotels in Rome City Centre and indulge in the finer things in life for a while.

5-Star Hotels in Rome City Centre

You'll have a wonderful time at one of these 5-star hotels. Exceptional customer care, luxurious bedding, and deeply relaxing spa offerings are waiting for you. You're sure to find exactly the accommodation you need. You can also expect excellent customer service from these hotels, so get ready for a wonderful adventure. What kind of amenities will make your stay a wonderful one? 24-hour room service, so you can order that berry tart in the wee hours of the morning? A body scrub that will leave you feeling refreshed and alive? Butler services? Whatever it is your heart desires, you're bound to find it here. Don't want to take our word for it? Explore our listings and pick the perfect accommodation for your needs. 

But you aren't going to spend your entire holiday in your room, of course. You're in luck. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Rome City Centre are waiting for you to relax after an exciting day.

Make Your Escape

The results are in, and Rome City Centre 5-star hotels are the place to be when you book your next holiday. If you've been dreaming about a holiday set here, then go ahead and book it. It's time to plan your next great escape -- this is a great time to find 5-star hotel deals in Rome City Centre! Choose one of our Rome City Centre 5-star hotels today and soothe yourself in luxe surroundings at your convenience.


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Frequently asked questions

How much does it cost to stay in a 5-star hotel in Rome City Centre?
There are many different pricing options for a 5-star hotel in Rome City Centre on Expedia. The amount you pay will depend on your travel dates, length of your trip and other factors. Compare available properties for your chosen dates and use our pricing and other filters to discover the perfect luxury stay.

  • Search for the lowest price per night from ₹15,605

What makes a hotel 5 stars in Rome City Centre?
In Rome City Centre, a hotel is required to offer a certain level of upscale conveniences to be rated 5 stars. These may include on-site gyms, gourmet restaurants, saunas and spas, premium bedding, complimentary luxury toiletries and more. What also sets 5-star hotels apart is their extraordinary standard of service. You'll enjoy things like in-room massages, nightly turn-down services and concierge services. Some may also offer thoughtful touches such as welcome gifts.
Are there any 5-star all-inclusive resorts in Rome City Centre?
Use our filters to find an upmarket retreat in Rome City Centre where everything you need is included in the price. Next, refine your results for resorts that have 5 stars and are deemed "All inclusive." The most important thing on the to-do list at these stays? Relaxation and indulgence.

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