Plan, book, travel with confidence
Better together
Save up to ₹43,962 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place

Top Luxury Central Iowa Hotels

Des Lux Hotel

800 Locust St Des Moines IA

1 hour drive from Iowa State University

Stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free Wi-Fi and a free airport shuttle. Our guests praise the breakfast and the bar ...

9.6/10 Exceptional! (1,034 reviews)

Clean hotel; excellent customer service!

Reviewed on 12 Dec 2025

Sonesta Essential Des Moines

4755 Merle Hay Road Des Moines IA

1 hour drive from Iowa State University

Stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the clean rooms in their reviews. Popular ...

7.4/10 Good! (1,002 reviews)

🙂

Reviewed on 13 Dec 2025

La Quinta Inn & Suites by Wyndham Des Moines West Clive

1390 Nw 118th St Clive IA

1 hour drive from Iowa State University

Stay at this family-friendly hotel in Clive. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in their ...

8.6/10 Excellent! (1,001 reviews)

Room was very clean and the staff was amazing.

Reviewed on 9 Dec 2025

See all 1,587 properties in Central Iowa

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.