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Top Luxury Central Iowa Hotels

Des Lux Hotel

800 Locust St Des Moines IA

1 hour drive from Iowa State University

Stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free Wi-Fi and a free airport shuttle. Our guests praise the breakfast and the bar ...

9.6/10 Exceptional! (1,035 reviews)

The front desk lady was very nice and helpful! This was one of my favorite places to stay. So thank you all.

Reviewed on 6 Feb 2026

Sonesta Essential Des Moines

4755 Merle Hay Road Des Moines IA

1 hour drive from Iowa State University

Stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the clean rooms in their reviews. Popular ...

7.4/10 Good! (1,000 reviews)

The room is clean and neat. Check in was a breeze. Clean decor and good staff makes this a good deal. I'd stay here again.

Reviewed on 26 Jan 2026

La Quinta Inn & Suites by Wyndham Des Moines West Clive

1390 Nw 118th St Clive IA

1 hour drive from Iowa State University

Stay at this family-friendly hotel in Clive. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in their ...

8.6/10 Excellent! (1,004 reviews)

Courteous daytime staff. The room was clean.

Reviewed on 2 Feb 2026

See all 1,601 properties in Central Iowa

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.