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Top Luxury South Carolina Midlands Hotels

The Ballantyne, A Luxury Collection Hotel, Charlotte

10000 Ballantyne Commons Pkwy Charlotte NC

3 hours drive from Fort Jackson

Stay at this luxury hotel in Charlotte. Enjoy free Wi-Fi, 2 indoor pools and a full-service spa. Our guests praise the helpful staff and the property condition ...

9.2/10 Wonderful! (1,001 reviews)

Great place

Reviewed on 30 Jan 2026

The Willcox

100 Colleton Avenue SW Aiken SC

2 hours drive from Fort Jackson

Stay at this business-friendly hotel in Aiken. Enjoy free breakfast, free parking and a fitness centre. Popular attractions The Alley and Aiken County Historical ...

9.6/10 Exceptional! (148 reviews)

Pet friendly! They even brought up fluffy dog beds and treats. Staff was wonderful

Reviewed on 7 Jan 2026

The Mantissa Hotel

130 East Carolina Ave Hartsville SC

2 hours drive from Fort Jackson

Stay at this hotel in Hartsville. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular attractions ...

9/10 Wonderful! (274 reviews)

This was an outstanding hotel We will stay again when in town

Reviewed on 18 Jan 2026

See all 3,163 properties in South Carolina Midlands

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.