The Best Hotels in Santa Lucia, Syracuse - 2026 Updated Prices

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Property	Property class	Guest rating
Giuggiulena Villa	3.0 star property	10.0 Exceptional 129 reviews	View
Caportigia Boutique Hotel	5.0 star property	9.4 Exceptional 279 reviews	View
Fortuna Guest House	1.0 star property	9.2 Wonderful 18 reviews	View
Hotel Palazzo Cavalieri	4.0 star property	9.0 Wonderful 42 reviews	View
Nostos rooms & Apartments	3.0 star property	9.0 Wonderful 281 reviews	View

Where to stay in Santa Lucia

Find the best Santa Lucia areas for the activities you enjoy most.

Ortigia

Ortigia is popular for its seaside views, and if you're looking for more to see and do, you might think about a trip to Cathedral of Syracuse or Piazza del Duomo.

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Neapolis

While visiting Neapolis, you might make a stop by sights like Roman Amphitheatre of Syracuse and Archaeological Park of Neapolis.

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Grottasanta

Grottasanta is noteworthy for its historical sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.

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Acradina

You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry.

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Syracuse, panoramic phot of the Roman Amphitheatre at Syracuse (Siracusa), UNESCO World Heritage Site, Sicily, Italy, Europe

Tiche

Gardens and restaurants are notable features of Tiche. You might consider stopping by Ionian Sea while you're exploring the neighbourhood.

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Top Santa Lucia Hotel Reviews

Algila' Ortigia Charme Hotel

10/10 Excellent

"We are a family of four, have traveled extensively and absolutely loved this hotel! Perfect location, able to valet park, breakfast included, but what really made it truly amazing is how friendly the staff were, including: Denise-who even helped us with our luggage to our room, Sonia-who was a delight in the morning at breakfast, even bringing us freshly squeezed orange juice (definitely get this!) and I’m not sure of his name, but the gentleman who made us cappuccinos every morning-he was wonderful. They were all simply delightful! If you are a runner, I highly recommend running along the water each morning. My only suggestion would be to make sure everything is removed from your car, we left with one less 12V charger, not a big deal, just take all of your belongings. Will definitely come back one day!"

Grand Hotel Villa Politi

8/10 Good

"The hotel is situated in a wonderful location, with beautiful surroundings that made our stay particularly enjoyable. The breakfast was a little below our expectations, and some of the amenities could benefit from updating. However, these were minor issues, and overall we had a very pleasant stay and would happily return."

Mangia's Brucoli, Sicily, Autograph Collection

10/10 Excellent

"The pictures online do not give Mangia Brucoli justice. It is more beautiful in person. Our room had Mt. Etna views that were breathtaking. We had breakfast included and wow it’s amazing. We visited the adult , kids pool and the beach. All were great. Ate in town (Brucoli) and had delicious meals. Strong recommendation!!!"

VOI Arenella Resort

10/10 Excellent

"We spent four nights in a Superior Triple Room, all-inclusive, and had an incredible time. The resort is vast, the food is incredible and the staff are very helpful. There is a genuine effort to offer food that is fresh, varied as well producing local delicacies. Although there is a shuttle bus frequently to Syracuse, we chose to spend all of our time within the resort alternating our time from the two wonderful pools and the beach. We would come back in a heartbeat and are interested in what other VOI resorts are available. It's worth noting that their season truly begins from 1st June meaning there are more activities from this date nevertheless we still enjoyed children's entertainment din late May despite their official season not starting quite yet. It's also worth noting that food and drink from the beach facility is excluded even if you have chosen all inclusive. 10/10 would go again!!!"

Grand Hotel Ortigia Siracusa

10/10 Excellent

"This is a fabulous old style hotel brought up to date in a really good location for Ortigia. The rooftop restaurant and terrace have a beautiful view and breakfast has a very large choice and is very good. The staff are extremely attentive and all seem to have the freedom to chat to guests like human beings and not "5 star robots". A welcome change."

Frequently asked questions

What is Santa Lucia like?

Santa Lucia is a neighbourhood that people enjoy for its interesting historical sites. Are you looking for Santa Lucia travel tips? Make sure that you visit Porto Piccolo and Ionian Sea while you're in the neighbourhood.

Where is the best hotel for a stay in Santa Lucia?

Based on our traveller data, Grande Albergo Alfeo is one of the top choices for your stay in Santa Lucia. This hotel offers free breakfast and a restaurant. Other good choices for your stay in the area include Caportigia Boutique Hotel and Fortaleza Charme House.

How many hotels will I find in Santa Lucia?

Expedia has 309 hotels and other accommodation options in Santa Lucia to choose from, making this an ideal home base for exploring the greater Syracuse area.

If I need to cancel my hotel reservation in Santa Lucia, will I receive a refund?

Yes! You'll find that most hotel room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to review the best options available in Santa Lucia.

What are the top things to see and do in Santa Lucia?

Landmarks in Santa Lucia that you won't want to miss include Syracuse Forum Ruins and Santa Lucia Bridge. Porto Piccolo and Ionian Sea are some other stops worth a visit in the neighbourhood. A few places to visit in the area around Santa Lucia include Piazza Santa Lucia, Santa Lucia al Sepolcro Basilica and Madonna delle Lacrime. When you're sightseeing in Syracuse, Papyrus Museum and Museo Archeologico Regionale Paolo Orsi are also worth a stop.

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Our top choices for Santa Lucia hotels

B&B IL MORO

Nostos rooms & Apartments

B&B Nike

Melody rooms

B&B L'INFIORESCENZA

Caportigia Boutique Hotel

Lakkios

B&B Siracusa

Piccolo Hotel Casa Mia

Le Camere Luxsury Rooms

Isonzo Suites

AmaCasa Siracusa

Calafatari B&B

Hotel Mediterraneo

Eos Elegant Apartment & Suites

Hotel Palazzo Cavalieri

Fortaleza Charme House

Gymnasium

Populus

Grande Albergo Alfeo

Compare popular hotels in Santa Lucia

Where to stay in Santa Lucia

Ortigia

Neapolis

Grottasanta

Acradina

Tiche

Top Santa Lucia Hotel Reviews

Algila' Ortigia Charme Hotel

Frequently asked questions

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