A coastal fortress with a stone wall and a tiled-roof building.

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Check availability on Syracuse Luxury Hotels

Tonight
2 Sept - 3 Sept
Tomorrow
3 Sept - 4 Sept
This weekend
4 Sept - 6 Sept
Next weekend
11 Sept - 13 Sept

Our top choices for Syracuse luxury hotels

1. Grand Hotel Des Ètrangers - The Leading Hotels of the World

Grand Hotel Des Ètrangers - The Leading Hotels of the World
Ortigia
  • Discover the epitome of Mediterranean luxury steps from Ortigia's coastline at this spa-focused retreat with poolside indulgence.
₹61,999
₹69,300 total
includes taxes & fees
14 Sept - 15 Sept
Grand Hotel Des Ètrangers - The Leading Hotels of the World

2. Ortea Palace Hotel, Sicily, Autograph Collection

Ortea Palace Hotel, Sicily, Autograph Collection
Ortigia
  • Mediterranean luxury awaits at this 5-star Syracuse hotel with spa, sauna, and two restaurants near Ortigia's beaches.
₹48,032
₹53,936 total
includes taxes & fees
4 Sept - 5 Sept
Ortea Palace Hotel, Sicily, Autograph Collection

3. Palazzo Artemide - VRetreats, SLH Collection

Palazzo Artemide - VRetreats, SLH Collection
Ortigia
  • Relax in a grand Beaux Arts hotel in Ortigia, where upscale comfort meets historic charm steps from Syracuse Cathedral.
₹52,159
₹58,475 total
includes taxes & fees
24 Sept - 25 Sept
Palazzo Artemide - VRetreats, SLH Collection

4. Minareto

Minareto
Syracuse
  • Syracuse seaside splendour offers indulgent relaxation with private beach access, beachfront dining, and Art Deco elegance.
₹39,470
₹44,523 total
includes taxes & fees
11 Sept - 12 Sept
Minareto

5. Wellness & Spa Hotel Principe di Fitalia

Wellness & Spa Hotel Principe di Fitalia
Syracuse
  • Sicilian spa escape boasts 2 outdoor pools and a serene full-service wellness centre.
₹44,803
₹50,384 total
includes taxes & fees
22 Sept - 23 Sept
Wellness & Spa Hotel Principe di Fitalia

6. Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa
Ortigia
  • Experience luxury at grand hotel with spa services, private beach, and seaside dining in Ortigia.
₹33,168
₹37,585 total
includes taxes & fees
7 Sept - 8 Sept
Grand Hotel Ortigia Siracusa

7. Dimora Caiammari Luxury Hotel & Spa

Dimora Caiammari Luxury Hotel & Spa
Syracuse
  • Coastal luxury awaits at this five-star retreat offering a full-service spa, two outdoor pools, and Mediterranean dining near Fanusa Beach.
₹31,701
₹35,972 total
includes taxes & fees
2 Oct - 3 Oct
Dimora Caiammari Luxury Hotel & Spa

8. Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel
Ortigia
  • Historic charm meets seaside luxury in Syracuse with private balconies, rainfall showers, and sea-view breakfast.
₹27,739
₹31,613 total
includes taxes & fees
3 Sept - 4 Sept
Algila' Ortigia Charme Hotel

9. Charme Hotel Henry's House

Charme Hotel Henry's House
Ortigia
  • Luxurious Mediterranean retreat offers memory foam beds, designer toiletries, and sea-view rooftop terrace in Ortigia.
₹29,492
₹33,542 total
includes taxes & fees
6 Sept - 7 Sept
Charme Hotel Henry's House

10. Caportigia Boutique Hotel

Caportigia Boutique Hotel
Santa Lucia
  • Elegant Mediterranean luxury, impeccable service, and fine dining near Ortigia await at this boutique Syracuse hotel.
₹20,013
₹23,116 total
includes taxes & fees
3 Sept - 4 Sept
Caportigia Boutique Hotel
View all properties

Top Syracuse Hotel Reviews

Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa

10/10 Excellent
"Old world Italian charm and great service. Would have preferred something more centrally located with a pool and better breakfast."
Karen 3-night trip
Posted 4 days ago
Grand Hotel Ortigia Siracusa
Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel

10/10 Excellent
"The hotel was very well located, offered 4 bicycles for use in town, andbfacilitatee seamless valet parking for our rented vehicle. The breakfasts"
Alfred 3-night trip
Posted 5 days ago
Algila' Ortigia Charme Hotel
 Palazzo Artemide - VRetreats, SLH Collection

Palazzo Artemide - VRetreats, SLH Collection

10/10 Excellent
"We liked the location and the high quality of the hotel. Bedroom a little small but not a major problem."
John and Stephanie 2-night trip
Posted 5 days ago
Palazzo Artemide - VRetreats, SLH Collection
Hotel Parco delle Fontane

Hotel Parco delle Fontane

10/10 Excellent
"Please clarify the specific procedures or instructions for gaining access to the facility, particularly regarding the address displayed at the gate."
Salvatore 1-night trip
Posted 8 days ago
Hotel Parco delle Fontane
Grande Albergo Alfeo

Grande Albergo Alfeo

10/10 Excellent
"Great spot in Siracusa and easy walk into Ortigia. The staff was friendly and Alessandro was a great help to us and answered our questions in English and Italian. Plus who can resist the refreshingly delicious free granita."
Elizabeth 3-night trip
Posted 8 days ago
Grande Albergo Alfeo

Frequently asked questions

Are you searching for a great accommodation for your luxury trip to Syracuse?
Travel to Catania (CTA-Fontanarossa) Airport or Comiso (CIY-Vincenzo Magliocco) Airport, and then treat yourself to a stay at one of 9 Syracuse luxury hotels. While you're visiting, you might want to think about enjoying the ruins and sightseeing, which Syracuse is known for.
What's the best luxury place to stay in Syracuse?
Ortea Palace Hotel, Sicily, Autograph Collection is a luxury hotel with 2 restaurants and a full-service spa, and it's a popular choice for Expedia travellers looking for an elegant place to stay. Grand Hotel Ortigia Siracusa and Grand Hotel Des Ètrangers - The Leading Hotels of the World are other upscale choices for your trip.
How many luxury hotels will I be able to find in Syracuse?
Lie in the lap of luxury during your getaway to Syracuse in one of Expedia's 9 luxury hotels.
When can I expect good weather in Syracuse?
Planning for the weather is a good way to make your trip to Syracuse relaxing and enjoyable, especially when you're splurging. The hottest months are usually August and July, with an average temperature of 25°C, while the coldest months are February and January, with an average of 14°C. Average annual precipitation for Syracuse is 653 mm.
What's there to see and do in Syracuse?
Experience all that Syracuse has to offer when you visit Temple of Apollo, Lungomare di Ortigia and Piazza del Duomo. If you have a little extra time during your trip, you might want to check out Cathedral of Syracuse and Porto Piccolo.
How can I get around Syracuse?
It's easier to get around town in style when you know your options. To venture out into the surrounding area, ride one of the trains from Syracuse Station or Targia Station.

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