Midtown Travel Guide
St. Louis
Popular places to visit
St. Louis University
Explore the campus of St. Louis University during your stay in St. Louis. Wander around the area's picturesque gardens or experience its acclaimed theatre scene.
Scott Joplin House State Historic Site
Learn about the local history of St. Louis when you take a trip to Scott Joplin House State Historic Site. Experience the area's acclaimed theatre scene or attend a baseball game.
Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.
St. Louis Union Station
You can learn more about the history of St. Louis during your trip to a well-known site such as St. Louis Union Station. Experience the area's fascinating museums or attend a baseball game.
Gateway Arch
Visit the Museum of Westward Expansion, then ascend to the top of the tallest man-made monument in the US for breathtaking views of St. Louis.
St. Louis Zoo
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
Top hotels in Midtown
Residence Inn by Marriott St Louis Downtown
Yes
Reviewed on 24 Apr 2026
Element St. Louis Midtown
My expedia says check in at 3:00. Hotel says 4:00 and they were terrible at communicating when rooms were done amd we didn’t get in until 4:30. Parking was ridiculously expensive and they put two pending charges for $192.00 and $242.00 before they figured out the correct amount. Had to call back ...
Reviewed on 24 Apr 2026
Hyatt Regency St. Louis at The Arch
Great food, great staff!
Reviewed on 24 Apr 2026
Clayton Plaza Hotel & Extended Stay
Only reason picked was for the indoor pool and game room for kids but was closed. Would've been nice to no before booking it they have a no refund policy
Reviewed on 24 Apr 2026
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
The hotel is very average but ok for the price. The room had a very small bathroom and looked like it had been patched up all over. The shower did not drain. Would stay in a pinch but would probably look for something else
Reviewed on 24 Apr 2026
Hollywood Casino & Hotel St. Louis
We were looking for a nice easy and safe stay in the St Louis area. This place was it. Staff is great food choices excellent and at no point did I feel like I was going to be stabbed. My best trip to St Louis yet!
Reviewed on 23 Apr 2026
Other neighbourhoods around Midtown
The Gate
While The Gate may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like St. Louis Union Station and Busch Stadium.
Downtown West
While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and St. Louis Aquarium at Union Station.
Lafayette Square
The restaurants and shopping are a few reasons travellers visit Lafayette Square. Want to see more of the surrounding area? St. Louis Union Station and Busch Stadium are a few top sights nearby.
The Grove
While there might not be top attractions in The Grove, you can explore the larger area and discover places like St. Louis Zoo and St. Louis Science Center.
Shaw
Shaw might not have many top sights, but Missouri Botanical Gardens and Arboretum and St. Louis Science Center are two attractions nearby that you can check out.
Central West End
If you're looking for things to see and do in Central West End, ample dining options and lush forests are highlights. You might also check out World Chess Hall of Fame while you're visiting, and jump aboard the metro at Central West End Station to get around town.
