Midtown Travel Guide
St. Louis
Popular places to visit
St. Louis University
Explore the campus of St. Louis University during your stay in St. Louis. Wander around the area's picturesque gardens or experience its fascinating museums.
Scott Joplin House State Historic Site
Learn about the local history of St. Louis when you take a trip to Scott Joplin House State Historic Site. Experience the area's great live music or attend a baseball game.
St. Louis Union Station
You can learn more about the history of St. Louis during your trip to a well-known site such as St. Louis Union Station. Experience the area's great live music or attend a baseball game.
Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's fascinating museums or attend a baseball game.
Gateway Arch
Visit the Museum of Westward Expansion, then ascend to the top of the tallest man-made monument in the US for breathtaking views of St. Louis.
Enterprise Center
Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's fascinating museums or attend a baseball game.
Top hotels in Midtown
Element St. Louis Midtown
No hot tub and the pool was cold as hell but other than that nice place
Reviewed on 7 Mar 2026
Residence Inn by Marriott St Louis Downtown
Housekeepers and staff were very nice except for the girl in the front
Reviewed on 4 Mar 2026
Pear Tree Inn St. Louis Near Union Station
Good value for the money. The hotel was clean, looked well maintained, the rooms were good-sized and nicely furnished. The staff was friendly and helpful. Being among the lower priced hotels in the area, it did attract a somewhat low-to-moderate level clientele.
Reviewed on 8 Mar 2026
Clayton Plaza Hotel & Extended Stay
Shower with select a temp the best! Free breakfast was great! Only bummer was $10 to park!
Reviewed on 8 Mar 2026
21C Museum Hotel St Louis
Unique hotel, would stay again
Reviewed on 7 Mar 2026
Drury Plaza Hotel St. Louis at the Arch
Staff was very friendly, very clean hotel.
Reviewed on 6 Mar 2026
Other neighbourhoods around Midtown
The Gate
While The Gate may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like St. Louis Union Station and Busch Stadium.
Downtown West
While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and St. Louis Aquarium at Union Station.
Lafayette Square
The restaurants and shopping are a few reasons travellers visit Lafayette Square. Want to see more of the surrounding area? St. Louis Union Station and Busch Stadium are a few top sights nearby.
The Grove
While there might not be top attractions in The Grove, you can explore the larger area and discover places like St. Louis Science Center and Missouri Botanical Gardens and Arboretum.
Shaw
Shaw might not have many top sights, but Missouri Botanical Gardens and Arboretum and St. Louis Science Center are two attractions nearby that you can check out.
Central West End
If you're looking for things to see and do in Central West End, ample dining options and lush forests are highlights. You might also check out World Chess Hall of Fame while you're visiting, and jump aboard the metro at Central West End Station to get around town.
