What is Midtown like?

Travellers are sure to enjoy a stay in St. Louis's Midtown neighbourhood. Make sure that you visit Chaifetz Arena and Washington Avenue Historic District as part of your Midtown travel plans.

Where is the best place to stay in Midtown?

Based on our traveller data, Element by Marriott St. Louis Midtown is one of the top choices for your stay in Midtown. This hotel is a short 6-minute walk from St. Louis University, and it offers free breakfast and an indoor pool.

How many hotels will I be able to find in the Midtown area?

If you're searching for places to stay in St. Louis, Expedia has something to meet your needs with 35 Midtown hotels and other accommodation options to choose from.

If I need to cancel my hotel reservation in Midtown, will I receive a refund?

Yes! Most hotel room reservations are refundable if you cancel before the hotel’s cancellation deadline, which often is within 24-48 hours of check in. If you have a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of booking. Add dates, click "Search", then use the filter option "fully refundable" to get top deals in Midtown.

What are the top things to see and do in Midtown?

Sights like Red Flag, Scott Joplin House State Historic Site and Museum of Contemporary Religious Art can be part of your cultural tour of Midtown. Chaifetz Arena and Washington Avenue Historic District are also a couple of places to visit in the neighbourhood. Favourite places to visit in the surrounding area include St. Louis Union Station, Enterprise Center and Gateway Arch. While you're out sightseeing, Hermann Stadium and .ZACK Theater are a couple of additional sights to visit in St. Louis.

How can I get around Midtown and the greater St. Louis area?

Ready to get out and explore the city? Grand Station is the closest metro station.

The Best Hotels in Midtown, St. Louis - 2026 Updated Prices

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Midtown hotels

1. Element by Marriott St. Louis Midtown

Midtown

Heather

₹14,811 total

includes taxes & fees

27 Sept - 28 Sept

2. Residence Inn by Marriott St Louis Downtown

Midtown

Patrick

₹12,554 total

includes taxes & fees

27 Sept - 28 Sept

3. Fairfield Inn & Suites by Marriott St. Louis Downtown

Downtown West, 1.3 km from Midtown

James

₹14,301 total

includes taxes & fees

4 Oct - 5 Oct

4. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

0.8 km from Midtown

Arturo

₹12,383 total

includes taxes & fees

27 Sept - 28 Sept

5. Pear Tree Inn St. Louis Near Union Station

Downtown West, 1.2 km from Midtown

Michael

₹13,072 total

includes taxes & fees

27 Sept - 28 Sept

6. Drury Plaza Hotel St. Louis Union Station

Downtown West, 1.5 km from Midtown

Katy

₹15,341 total

includes taxes & fees

21 Sept - 22 Sept

7. Courtyard by Marriott St. Louis Downtown West

Downtown West, 1.1 km from Midtown

Jonathan

₹13,027 total

includes taxes & fees

27 Sept - 28 Sept

8. Hampton Inn & Suites St. Louis at Forest Park

Dogtown, 4.8 km from Midtown

Jim

₹15,682 total

includes taxes & fees

30 Sept - 1 Oct

9. Embassy Suites by Hilton St. Louis Downtown

Downtown St. Louis, 3.1 km from Midtown

Andrew

₹13,008 total

includes taxes & fees

11 Oct - 12 Oct

10. Drury Plaza Hotel St. Louis at the Arch

Downtown St. Louis, 3.4 km from Midtown

Salvatore

₹15,147 total

includes taxes & fees

4 Oct - 5 Oct

11. Aloft by Marriott St Louis Central West End

Central West End, 2.2 km from Midtown

Changsuk

₹12,727 total

includes taxes & fees

28 Sept - 29 Sept

12. Hyatt Regency St. Louis at The Arch

Downtown St. Louis, 3.4 km from Midtown

Trevion

₹17,140 total

includes taxes & fees

1 Oct - 2 Oct

13. Tru By Hilton St. Louis Downtown

Downtown West, 2.5 km from Midtown

isabel

₹10,903 total

includes taxes & fees

27 Sept - 28 Sept

14. Home2 Suites by Hilton St. Louis Downtown

Downtown West, 2.5 km from Midtown

kaila

₹10,903 total

includes taxes & fees

27 Sept - 28 Sept

15. Courtyard by Marriott St. Louis Downtown/Convention Center

Downtown St. Louis, 2.9 km from Midtown

Kristy

₹12,514 total

includes taxes & fees

27 Sept - 28 Sept

16. Live by Loews - St.Louis

Downtown St. Louis, 3 km from Midtown

Judd

₹18,146 total

includes taxes & fees

27 Sept - 28 Sept

17. 21C Museum Hotel St Louis

Downtown West, 2.1 km from Midtown

Zane

₹16,529 total

includes taxes & fees

11 Oct - 12 Oct

Indoor pool, open 6:00 AM to 10:00 PM, pool loungers

18. Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Downtown St. Louis, 3.5 km from Midtown

Alexander

₹13,652 total

includes taxes & fees

26 Sept - 27 Sept

Premium bedding, down duvets, pillow-top beds, in-room safe

19. The Westin St. Louis

Downtown St. Louis, 2.9 km from Midtown

Joanne

₹15,206 total

includes taxes & fees

27 Sept - 28 Sept

In-room safe, desk, blackout curtains, iron/ironing board

20. DoubleTree by Hilton St. Louis Forest Park

Central West End, 3.1 km from Midtown

Morgan

₹17,869 total

includes taxes & fees

27 Sept - 28 Sept

View all properties

Where to stay in Midtown

Find the best Midtown areas for the activities you enjoy most.

The Gateway Arch in St. Louis, Missouri, with a well-maintained lawn and trees in the foreground.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Gateway Arch National Park – discover Downtown St. Louis, a destination also famous for its historic sites.

See properties

A gazebo by a calm pond with autumn foliage and clear skies.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

See properties

A street corner with a 'Drunken Fish' sushi restaurant and a 'Culpeppers' grill and bar.

Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

See properties

A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

See properties

A wooden bridge with metal trusses, surrounded by trees.

St. Charles Historic District

St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Missouri River while in the area.

See properties

Top Midtown Hotel Reviews

Pear Tree Inn St. Louis Airport

10/10 Excellent

"Everything was so clean and well maintained! The staff were excellent! They were friendly and helpful. They also seemed happy! We will definitely stay here again and highly recommend it!"