What is Midtown like?

Travellers are sure to enjoy a stay in St. Louis's Midtown neighbourhood. Make sure that you visit Chaifetz Arena and Washington Avenue Historic District as part of your Midtown travel plans.

Where is the best place to stay in Midtown?

Based on Expedia customer reviews, Element St. Louis Midtown is the highest ranked property in Midtown. This hotel is a short 6-minute walk from St. Louis University, and it offers free breakfast and an indoor pool. Another top choice in the area is Residence Inn by Marriott St Louis Downtown .

How many hotels will I be able to find in the Midtown area?

If you're searching for places to stay in St. Louis, Expedia has something to meet your needs with 30 Midtown hotels and other accommodation options to choose from.

If I need to cancel my hotel reservation in Midtown, will I receive a refund?

Yes! Most hotel room reservations are refundable if you cancel before the hotel’s cancellation deadline, which often is within 24-48 hours of check in. If you have a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of booking. Add dates, click "Search", then use the filter option "fully refundable" to get top deals in Midtown.

What are the top things to see and do in Midtown?

Explore Midtown's landmarks such as Washington Avenue Historic District, Samuel Cupples House and Scott Joplin House State Historic Site and learn about the local history. Chaifetz Arena and Topgolf are also a couple of places to visit in the neighbourhood. Favourite places to visit in the surrounding area include St. Louis Union Station, Busch Stadium and Gateway Arch. While you're out sightseeing, .ZACK Theater and The MOTO Museum are a couple of additional sights to visit in St. Louis.

How can I get around Midtown and the greater St. Louis area?

Ready to get out and explore the city? Grand Station is the closest metro station.

The Best Hotels in Midtown, St. Louis - 2026 Updated Prices

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Our top choices for Midtown hotels

Element St. Louis Midtown

Midtown

Clare

₹14,361 total

includes taxes & fees

28 Jan - 29 Jan

Residence Inn by Marriott St Louis Downtown

Midtown

Christopher-Joi

₹12,334 total

includes taxes & fees

2 Feb - 3 Feb

Red Roof Inn St Louis - Troy, IL

29.4 km from Midtown

Fay

₹6,855 total

includes taxes & fees

15 Feb - 16 Feb

Holiday Inn Express Troy by IHG

29.4 km from Midtown

Tabatha

₹10,399 total

includes taxes & fees

25 Jan - 26 Jan

Super 8 by Wyndham Troy IL/St. Louis Area

29.2 km from Midtown

Kelley

₹6,432 total

includes taxes & fees

10 Feb - 11 Feb

Drury Inn & Suites St. Louis O'Fallon, IL

26.6 km from Midtown

Terry

₹11,184 total

includes taxes & fees

1 Feb - 2 Feb

Country Hearth Inn & Suites Edwardsville St. Louis

27.6 km from Midtown

James

₹9,519 total

includes taxes & fees

22 Jan - 23 Jan

Comfort Inn Edwardsville - St. Louis

24.2 km from Midtown

Carlos

₹10,016 total

includes taxes & fees

8 Feb - 9 Feb

Drury Inn & Suites St. Louis Collinsville

19.5 km from Midtown

Kyle

₹10,243 total

includes taxes & fees

15 Feb - 16 Feb

Room, 1 Queen Bed, Jetted Tub | Blackout curtains, free WiFi, bed sheets

Red Lion Inn & Suites Pontoon Beach

19.7 km from Midtown

Saulius

₹6,117 total

includes taxes & fees

25 Jan - 26 Jan

Best Western Plus Pontoon Beach

18.3 km from Midtown

Raeisha

₹8,631 total

includes taxes & fees

25 Jan - 26 Jan

Casino Queen Hotel

4.5 km from Midtown

Suzy

₹8,873 total

includes taxes & fees

10 Feb - 11 Feb

Indoor pool, open 6:00 AM to 10:00 PM, pool loungers

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Downtown St. Louis, 3.5 km from Midtown

Candi

₹10,380 total

includes taxes & fees

28 Jan - 29 Jan

Holiday Inn Express & Suites - O'Fallon /Shiloh by IHG

27.2 km from Midtown

Dale

₹10,899 total

includes taxes & fees

2 Feb - 3 Feb

Missouri Athletic Club

Downtown St. Louis, 3.4 km from Midtown

Annette

₹15,178 total

includes taxes & fees

29 Jan - 30 Jan

Drury Inn & Suites St. Louis Fairview Heights

21.2 km from Midtown

RANJITH

₹9,661 total

includes taxes & fees

26 Jan - 27 Jan

Hyatt Regency St. Louis at The Arch

Downtown St. Louis, 3.4 km from Midtown

Jennifer

₹15,987 total

includes taxes & fees

24 Jan - 25 Jan

Comfort Inn Collinsville near St. Louis

19.4 km from Midtown

Marcie

₹10,300 total

includes taxes & fees

1 Feb - 2 Feb

Hilton Pennywell St. Louis at the Arch

Downtown St. Louis, 3.4 km from Midtown

Dorris

₹11,501 total

includes taxes & fees

28 Jan - 29 Jan

Drury Plaza Hotel St. Louis at the Arch

Downtown St. Louis, 3.4 km from Midtown

Heather

₹13,934 total

includes taxes & fees

26 Jan - 27 Jan

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Where to stay in Midtown

Find the best Midtown areas for the activities you enjoy most.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Busch Stadium – discover Downtown St. Louis, a destination also famous for its historic sites.

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Berkeley

Visitors highly recommend Berkeley for its abundant dining options, and you can make a stop by James S. McDonnell Prologue Room while you're in town.

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Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

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Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

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