Southern Indiana Trip

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Where to stay in Southern Indiana

Find the best Southern Indiana areas and neighborhoods for the activities you enjoy most. Learn more about Southern Indiana
Louisville Science Center which includes outdoor art

West Main Historic District

A noteworthy feature of West Main Historic District is its fantastic nightlife. While you're in town, be sure to stop and check out Frazier International History Museum and Louisville Slugger Museum.

Find hotels in West Main Historic District

Top hotels in Southern Indiana

Radisson Hotel Louisville North

Radisson Hotel Louisville North

3 out of 5
505 Marriott Drive Clarksville IN
Fully refundableReserve now, pay when you stay
The price is ₹5,439 per night from 12 Apr to 13 Apr
₹5,439
₹6,146 total
12 Apr - 13 Apr
includes taxes & fees
7/10 Good! (2,828 reviews)
Clean quiet close to Louisville plenry of parking

Reviewed on 10 Mar 2026

Radisson Hotel Louisville North
Fairfield Inn By Marriott Evansville East

Fairfield Inn By Marriott Evansville East

3 out of 5
7879 Eagle Crest Blvd Evansville IN
Fully refundableReserve now, pay when you stay
The price is ₹7,745 per night from 22 Mar to 23 Mar
₹7,745
₹8,907 total
22 Mar - 23 Mar
includes taxes & fees
8.8/10 Excellent! (472 reviews)
Clean room and friendly staff. Older building but well maintained. Breakfast is the same pre-packaged eggs and meats as other hotel chains. It would be nice to see some fresh options available

Reviewed on 4 Mar 2026

Fairfield Inn By Marriott Evansville East
Derby Hotel & Suites

Derby Hotel & Suites

2 out of 5
505 K Marriot Dr Clarksville IN
Fully refundable
The price is ₹5,237 per night from 19 Mar to 20 Mar
₹5,237
₹5,917 total
19 Mar - 20 Mar
includes taxes & fees
Derby Hotel & Suites
See all 1,627 properties in Southern Indiana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Panorama Ohio River waterway riverboats and bridges leading to heart of downtown Louisville KY

KFC Yum Center

3/5(2 reviews)

Catch an event at KFC Yum Center during your trip to Louisville. Stroll along the riverfront or attend a sporting event in the area.

KFC Yum Center
Holiday World and Splashin\' Safari featuring a waterpark as well as a small group of people

Holiday World and Splashin' Safari

Every day is a holiday at this fun-filled combination theme park and water park, where visitors of all ages can explore roller coasters, raft rides and wave pools.

Holiday World and Splashin' Safari
A fun place to go for night life.

Fourth Street Live!

4/5(5 reviews)

You can do some window-shopping at Fourth Street Live! during your visit to Louisville. Experience the area's entertainment choices and lively festivals.

Fourth Street Live!

Frequently asked questions

Can I cancel my flight booking to Southern Indiana due to COVID-19?
Our handy Customer Service Portal is your one-stop shop for almost every travel question, including about flight changes and cancellations due to COVID-19. For more peace of mind, look over the terms and conditions of your fare before reserving a seat.
What's the best way to find cheap flights to Southern Indiana that have flexible change policies?
At Expedia, we've been channeling our inner yoga master to get you the most flexible fares around town. Simply check the "No change fee" box right underneath the "Flexible change policies" heading to find your perfect flight to Southern Indiana.
What are some of the general tips for travellers to Southern Indiana during the COVID-19 outbreak?
If it's your first time travelling during the COVID-19 pandemic, you'll notice a raft of new standards and rules in place. Take note of these tips and make your escape to Southern Indiana a smooth one:
  • Find out if any travel restrictions apply to your origin and destination before locking in a flight. Also check if there are any requirements you'll have to follow on arrival, such as proof of a negative COVID-19 test.
  • Keep your face mask on during airport screening. A TSA officer will require you to lower your mask temporarily for ID purposes.
  • To reduce the possibility of cross-contamination, position your boarding pass on the scanner yourself and then hold it up for inspection. Do not hand your boarding pass directly to a TSA employee.
  • One container of liquid hand sanitizer is now allowed in your carry-on luggage. It must be no larger than 12 oz (350 ml), and you'll have to remove it from your bag for scanning.
  • To reduce handling during the screening process, put items such as your belt, phone and wallet into your carry-on instead of the bins.
  • If you're planning to take food on board, place it in a clear plastic bag and then into a scanning bin. This reduces the likelihood that a TSA officer will need to handle your food container or carry-on bag for closer inspection.

Which airlines fly to Southern Indiana?
Let Delta take you there. This leading carrier schedules 121 flights per month to Evansville Regional Airport (EVV), a Southern Indiana gateway.
How can I find cheap tickets to Southern Indiana?
Start searching as early as possible, fly in or out of nearby airports, use miles or points — there's no shortage of ways! One more is to use Expedia's "flexible dates" function. Find your Southern Indiana flight, then compare the prices for nearby dates. In the last seven days, the best price for a flight to Southern Indiana was .
How much is a flight to Southern Indiana?
There were a lot of cheap fares up for grabs in the last seven days, with the price of a return ticket to Southern Indiana varying between and . Many lucky holiday makers purchased one-way flights from () for as low as .
What are the most popular airports to fly into in Southern Indiana?
Jet into Evansville Regional Airport (EVV) and experience all that Southern Indiana has to offer. As the region's primary entry point, roughly 381 flights land here every month.
When is the cheapest time to fly to Southern Indiana?
If you'd prefer to spend your holiday cash on having fun in Southern Indiana rather than on getting there, leave early in the week. The most economical day to travel is normally Tuesday, with Monday a close second. With many people travelling over the weekend, Saturday often has the costliest fares.
How much is a plane ticket to Southern Indiana?
Seats to Southern Indiana ranged from to in the last seven days. Usually, the sooner you make a reservation, the bigger the bargain.
Which airlines with flights to Southern Indiana employ COVID-19 cleanliness policies?
In response to the current pandemic, the majority of airlines have rolled out additional steps and actions to help everybody get back in the air. Here's what these carriers are doing:
  • American Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.
  • Delta - this airline is known for electrostatic cleaning and cleaning with disinfectant.
  • United Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.

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