Search Spa Hotels in Southeast Missouri
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on Southeast Missouri Spa Hotels
Tonight
21 Sept - 22 SeptTomorrow
22 Sept - 23 SeptThis weekend
25 Sept - 27 SeptNext weekend
2 Oct - 4 OctOur top choices for Southeast Missouri hotels with a spa
1. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
- Luxurious spa sanctuary awaits with full-service treatments and indoor pool in this centrally located hotel.
₹9,677
₹11,014 total
includes taxes & fees
4 Oct - 5 Oct
Top Southeast Missouri Hotel Reviews
Drury Inn & Suites Hayti Caruthersville
10/10 Excellent
"Great stay, clean rooms, excellent breakfast! Will stay again if we are in the area."
Drury Inn & Suites Poplar Bluff
10/10 Excellent
"Clean, great food, excellent staff."
Explore a world of travel with Expedia
- Advance Hotels
- Motels in Alley Spring
- Arcadia Hotels
- B&B in Benton
- Black Hotels
- Bunker Hotels
- Luxury Hotels in Caledonia
- Resorts in Cape Girardeau
- All-Inclusive Hotels in Cape Girardeau
- Cheap Hotels in Cape Girardeau
- Hotels with Breakfast in Cape Girardeau
- Motels in Cape Girardeau
- Cape Girardeau County Hotels
- Eminence Hotels
- Farmstay in French Village
- French Village Hotels
- Resorts in Greenville
- Cheap Hotels in Jackson
- Hotels Suites in Jackson
- Hotels near Mark Twain National Forest
- Hotels near Ozark National Scenic Riverways
- Hotels near Southeast Missouri State University
- Cheap Hotels in St Mary
- Castles in Ste Genevieve
- Ste Genevieve Hotels