Photo by Alice Burghart

Search Hotel Resorts in Cape Girardeau

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
26 Dec - 28 Dec
In two weeks
2 Jan - 4 Jan
In one month
16 Jan - 18 Jan
In two months
13 Feb - 15 Feb
No exact matches found, but these alternatives could be just right

Recommended hotels in Cape Girardeau

Lobby
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1004)
"Great place and staff, very accommodating!"
United States
Megan
The price is ₹8,165
₹9,210 total
includes taxes & fees
21 Dec - 22 Dec
Drury Plaza Hotel Cape Girardeau Conference Center
Lobby sitting area
The Riverview

The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (473)
"The room was clean and the mattress was extremely comfortable "
United States
Stacy
The price is ₹8,040
₹9,070 total
includes taxes & fees
18 Dec - 19 Dec
The Riverview
Lobby
Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (139)
"Nice hotel, clean and comfortable "
United States
Laura
The price is ₹7,984
₹9,008 total
includes taxes & fees
25 Dec - 26 Dec
Fairfield Inn & Suites by Marriott Cape Girardeau
Lobby
Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (468)
"The staff was very helpful and friendly. The rooms were modern and clean. The downtown location was perfect for us. "
United States
Deborah
The price is ₹10,489
₹11,885 total
includes taxes & fees
29 Dec - 30 Dec
Courtyard by Marriott Cape Girardeau Downtown
Lobby
Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1002)
"Nice place for a stay at a reasonable price."
United States
Arthur
The price is ₹6,329
₹7,140 total
includes taxes & fees
4 Jan - 5 Jan 2026
Pear Tree Inn Cape Girardeau Near the Medical Center
Room, 2 Queen Beds
Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (102)
"It was a nice stay"
United States
Douglas
The price is ₹7,912
₹9,005 total
includes taxes & fees
1 Jan - 2 Jan 2026
Tru By Hilton Cape Girardeau
Exterior
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1001)
"We like to stay at this hotel on our way to New Orleans and on our return trip to Wisconsin. It is convenient, clean, breakfast options are excellent and the 8 pm cookie time is always a hit. Staff are also very friendly. "
United States
Brian
The price is ₹8,620
₹9,724 total
includes taxes & fees
23 Dec - 24 Dec
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Business centre
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1003)
"Very friendly staff and great breakfast"
United States
Ray
The price is ₹8,165
₹9,210 total
includes taxes & fees
21 Dec - 22 Dec
Drury Inn & Suites Cape Girardeau
Courtyard
Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (784)
"Excellent stay"
United States
Christina
The price is ₹9,226
₹10,408 total
includes taxes & fees
23 Dec - 24 Dec
Hampton Inn Cape Girardeau I 55 East
Standard Room, 1 Queen Bed, Non Smoking, Garden View | Free WiFi
Rockwood Inn

Rockwood Inn

Rockwood Inn
2.0 star property
Cape Girardeau
10.0 out of 10, Exceptional, (18)
"We came into town for a concert and had a blast! The hotel was super comfy, and the staff were friendly. The rooms were very clean and the decor was beautiful! "
United States
Vanessa
The price is ₹12,546
₹14,153 total
includes taxes & fees
17 Dec - 18 Dec
Rockwood Inn
Lobby
Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
2.5 star property
Cape Girardeau
7.2 out of 10, Good, (683)
"Overall was wonderful customer service and breakfast"
United States
Stephanie
The price is ₹5,414
₹6,108 total
includes taxes & fees
1 Jan - 2 Jan 2026
Quality Inn Cape Girardeau North
Exterior
Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
2.5 star property
Cape Girardeau
8.2 out of 10, Very good, (882)
"Room was clean and spacious."
United States
George
The price is ₹6,351
₹7,664 total
includes taxes & fees
11 Jan - 12 Jan 2026
Candlewood Suites Cape Girardeau by IHG
Lobby
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1002)
"Great stay"
United States
Heather
The price is ₹6,329
₹7,140 total
includes taxes & fees
4 Jan - 5 Jan 2026
Pear Tree Inn Cape Girardeau West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Cape Girardeau Hotel Reviews

Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG

10/10 Excellent
"Room was clean and spacious."
George 1-night trip
Posted 1 day ago
Candlewood Suites Cape Girardeau by IHG

Find out more about Cape Girardeau

Cape Girardeau Resorts information

Number of reviews
8,549
Accommodation
0 Resorts
Lowest Price
₹6,108
Highest Price
₹14,153

Frequently asked questions

What is Cape Girardeau like for a resort holiday?
Expedia can help you browse resorts and other accommodation options that offer similar amenities and comforts. If you have trouble with finding a resort in Cape Girardeau that meets your needs, you can use the search filters to look for hotels, or search for properties with amenities such as swimming pools or all-inclusive rates. We make it easy to book great accommodation so you can move on to creating your trip itinerary.
What can I do in Cape Girardeau?
Travellers enjoy visiting the historic sites and other landmarks in Cape Girardeau, and have good things to say about activities such as shopping. If you've brought the kids, you can head to Cape Splash Family Aquatic Center or Cape Girardeau Conservation Nature Center for some family fun. Isle Casino Cape Girardeau and Show Me Center are a few additional attractions in the area that you might like.
What's the weather like in Cape Girardeau?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Cape Girardeau is 1495 mm.
What's the best way to get to and around Cape Girardeau?
Fly into Cape Girardeau, MO (CGI-Cape Girardeau Municipal), which is located 6 mi (9.7 km) from the city centre. Otherwise, look for flights into Cairo, IL (CIR-Cairo Regional), which is 23.4 mi (37.6 km) away. If you'd like to explore around the area, you may want a rental car for your journey.

Explore a world of travel with Expedia