Southeast Missouri Trip

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Top hotels in Southeast Missouri

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive Cape Girardeau MO
Fully refundableReserve now, pay when you stay
The price is ₹10,493 per night from 26 Jul to 27 Jul
₹10,493
₹11,839 total
26 Jul - 27 Jul
includes taxes & fees
9.6/10 Exceptional! (1,015 reviews)
"We really enjoy staying here. It's clean, beds are comfortable. Breakfast is very goods and lots of choices."

Reviewed on 7 Jul 2026

Drury Plaza Hotel Cape Girardeau Conference Center
Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO

2.5 out of 5
1625 W Columbia St Farmington MO
Fully refundableReserve now, pay when you stay
The price is ₹6,258 per night from 3 Aug to 4 Aug
₹6,258
₹6,812 total
3 Aug - 4 Aug
includes taxes & fees
8/10 Very good! (1,014 reviews)
"This is an Asian Indian owned property. They typically do not keep up their properties well"

Reviewed on 7 Jul 2026

Baymont Inn and Suites by Wyndham Farmington, MO
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
Fully refundableReserve now, pay when you stay
The price is ₹10,540 per night from 14 Jul to 15 Jul
₹10,540
₹12,119 total
14 Jul - 15 Jul
includes taxes & fees
9.6/10 Exceptional! (1,007 reviews)
"We had a very good visit here. The staff was so friendly and helpful. Our room was spacious and clean. The A/C was so cool in the room."

Reviewed on 7 Jul 2026

Drury Inn & Suites Sikeston, MO
See all 673 properties in Southeast Missouri
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Southeast Missouri attractions

A large, reddish-brown rock formation with a smooth, rounded surface and a unique, intertwined shape.
Photo by Pat Long
Open Photo by Pat Long

Elephant Rocks State Park

9.6/10 (98 reviews)
You can take time to visit Elephant Rocks State Park during your travels to Ironton. While you're in the area, wander around the parks.
See properties

Frequently asked questions

How much does a Southeast Missouri holiday package cost?
Cross off another part of the world with our Southeast Missouri holiday packages, which start from just . Select the flights and hotels that match your travel plans. Then, add on one or two tours or experiences for an unforgettable adventure.
How do I get a cheap travel package to Southeast Missouri?
Browse and book everything in the one place with our Southeast Missouri holiday packages. You'll find deals on flights, hotels, tours and more that'll keep your pocket happy and your adventurous spirit alive. And, with more than 550 partner airlines and 1,000,000 hotels around the world to select from, you'll have endless opportunities to mix and match your own way.
What are the top hotels in Southeast Missouri?
When it comes to properties in Cape Girardeau, Drury Plaza Hotel Cape Girardeau Conference Centre and Pear Tree Inn Cape Girardeau West are a couple of favourites. If you're considering heading to Ste Genevieve, City Place St. Louis Downtown and The Branson Hillside Hotel are waiting to welcome you.
How far in advance should I book my Southeast Missouri holiday?
It's tricky picking the perfect time for airfares, but we generally say the earlier, the better. Many international journeys on Expedia become available up to a year in advance. If you can't book ahead, don't worry. Cheap prices appear from time to time within a few weeks of departure dates.
What does an Expedia Southeast Missouri travel package include?
From hotels and flights to car rentals, Expedia can help you craft a Southeast Missouri package that fits you. Holidaying for a week or two? Look into a rental car, hotel and flight bundle. If you're taking a quick break, a hotel and airfare deal may suit you better. Experiences can also be added once you've made your booking. Our packages make it a breeze to plan and save.
What should I know before booking a Southeast Missouri travel package?
When you book your flights, hotels and car rentals together, you'll pick up terrific discounts. Whether you're planning a beach escape in a villa or prefer to stay in a comfortable hotel in the city, Expedia will help make it happen.
Can I choose my airline with a Southeast Missouri Expedia holiday package?
You can, and with over 550 airlines to pick from around the world, you're spoiled for choice. Have a look through the available options and see which airline best suits your budget and needs.
If I'm not able to travel, can I cancel my Southeast Missouri holiday package?
Because we understand life is full of surprises, the answer is yes. To learn more, head to our Customer Service Portal. But generally speaking, if you've booked your Southeast Missouri holiday package in the last 24 hours, you may be able to cancel or change it for no charge. Your hotel, airline or car rental company may charge a fee if your booking is older than that.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.